Dom G et al. |
5-aza-2'-deoxycytidine has minor effects on differentiation in human thyroid cancer cell lines, but modulates genes that are involved in adaptation in vitro. |
2013 |
Thyroid |
pmid:23167291
|
Soriano FX et al. |
SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites. |
2013 |
J. Neurochem. |
pmid:23083128
|
Chen J et al. |
Prevention of cytotoxicity of nickel by quercetin: the role of reactive oxygen species and histone acetylation. |
2013 |
Toxicol Ind Health |
pmid:22294440
|
Poplineau M et al. |
Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells. |
2013 |
Cell Prolif. |
pmid:23510467
|
Ding SZ et al. |
Epithelial-mesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cells. |
2013 |
Toxicol. Appl. Pharmacol. |
pmid:23518002
|
Azechi T et al. |
Trichostatin A, an HDAC class I/II inhibitor, promotes Pi-induced vascular calcification via up-regulation of the expression of alkaline phosphatase. |
2013 |
J. Atheroscler. Thromb. |
pmid:23518467
|
Shah RR et al. |
Regulation of primitive hematopoiesis by class I histone deacetylases. |
2013 |
Dev. Dyn. |
pmid:23184530
|
Gao SM et al. |
Histone deacetylases inhibitor sodium butyrate inhibits JAK2/STAT signaling through upregulation of SOCS1 and SOCS3 mediated by HDAC8 inhibition in myeloproliferative neoplasms. |
2013 |
Exp. Hematol. |
pmid:23111066
|
Liu RF et al. |
Down-regulation of miR-517a and miR-517c promotes proliferation of hepatocellular carcinoma cells via targeting Pyk2. |
2013 |
Cancer Lett. |
pmid:23142219
|
Liu S et al. |
Up-regulation of miR-182 expression after epigenetic modulation of human melanoma cells. |
2013 |
Ann. Surg. Oncol. |
pmid:22752337
|
Ononye SN et al. |
Tropolones as lead-like natural products: the development of potent and selective histone deacetylase inhibitors. |
2013 |
ACS Med Chem Lett |
pmid:24900743
|
Piazza R et al. |
Epigenetic silencing of the proapoptotic gene BIM in anaplastic large cell lymphoma through an MeCP2/SIN3a deacetylating complex. |
2013 |
Neoplasia |
pmid:23633923
|
Camolotto SA et al. |
PSG gene expression is up-regulated by lysine acetylation involving histone and nonhistone proteins. |
2013 |
PLoS ONE |
pmid:23418492
|
Viñuelas J et al. |
Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts. |
2013 |
BMC Biol. |
pmid:23442824
|
Chachadi VB et al. |
Prostatic cell-specific regulation of the synthesis of MUC1-associated sialyl Lewis a. |
2013 |
PLoS ONE |
pmid:23451223
|
Kim YJ et al. |
HDAC inhibitors induce transcriptional repression of high copy number genes in breast cancer through elongation blockade. |
2013 |
Oncogene |
pmid:23435418
|
Moreaux J et al. |
Gene expression-based prediction of myeloma cell sensitivity to histone deacetylase inhibitors. |
2013 |
Br. J. Cancer |
pmid:23868005
|
Matsushita Y et al. |
HDAC inhibitors restore C-fibre sensitivity in experimental neuropathic pain model. |
2013 |
Br. J. Pharmacol. |
pmid:24032674
|
Singh RK et al. |
Kinetic and thermodynamic rationale for suberoylanilide hydroxamic acid being a preferential human histone deacetylase 8 inhibitor as compared to the structurally similar ligand, trichostatin a. |
2013 |
Biochemistry |
pmid:24079912
|
Day JA and Cohen SM |
Investigating the selectivity of metalloenzyme inhibitors. |
2013 |
J. Med. Chem. |
pmid:24074025
|
Fan J et al. |
Inhibition of HDAC2 protects the retina from ischemic injury. |
2013 |
Invest. Ophthalmol. Vis. Sci. |
pmid:23696608
|
Li M et al. |
Upregulation of Toll-like receptor 2 gene expression by acetylation of AP-2 alpha in THP-1 cells, a human monocytic cell line. |
2013 |
Int. J. Biochem. Cell Biol. |
pmid:23680675
|
Zhang Z et al. |
Stemness and inducing differentiation of small cell lung cancer NCI-H446 cells. |
2013 |
Cell Death Dis |
pmid:23681228
|
Kannan V et al. |
Histone deacetylase inhibitors suppress immune activation in primary mouse microglia. |
2013 |
J. Neurosci. Res. |
pmid:23686642
|
Murko C et al. |
Histone deacetylase inhibitor Trichostatin A induces neural tube defects and promotes neural crest specification in the chicken neural tube. |
2013 |
Differentiation |
pmid:23328540
|
Algamas-Dimantov A et al. |
Epigenetic control of HNF-4α in colon carcinoma cells affects MUC4 expression and malignancy. |
2013 |
Cell Oncol (Dordr) |
pmid:23307400
|
Johnson D and Walmsley R |
Histone-deacetylase inhibitors produce positive results in the GADD45a-GFP GreenScreen HC assay. |
2013 |
Mutat. Res. |
pmid:23340162
|
Zhou G et al. |
HSV carrying WT REST establishes latency but reactivates only if the synthesis of REST is suppressed. |
2013 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:23341636
|
Sharifulina SA et al. |
Epigenetic regulation of death of crayfish glial cells but not neurons induced by photodynamic impact. |
2014 |
Brain Res. Bull. |
pmid:24502940
|
Nieto-Pelegrin E et al. |
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector. |
2014 |
Cell Adh Migr |
pmid:25482634
|
Lv W et al. |
Histone deacetylase 1 and 3 regulate the mesodermal lineage commitment of mouse embryonic stem cells. |
2014 |
PLoS ONE |
pmid:25412078
|
Lu HK et al. |
Ex vivo response to histone deacetylase (HDAC) inhibitors of the HIV long terminal repeat (LTR) derived from HIV-infected patients on antiretroviral therapy. |
2014 |
PLoS ONE |
pmid:25409334
|
Yang W et al. |
Effect of trichostatin A on gelsolin levels, proteolysis of amyloid precursor protein, and amyloid beta-protein load in the brain of transgenic mouse model of Alzheimer's disease. |
2014 |
Curr Alzheimer Res |
pmid:25387339
|
Lu HG et al. |
TET1 partially mediates HDAC inhibitor-induced suppression of breast cancer invasion. |
2014 |
Mol Med Rep |
pmid:25175940
|
Zohre S et al. |
Trichostatin A-induced apoptosis is mediated by Kruppel-like factor 4 in ovarian and lung cancer. |
2014 |
Asian Pac. J. Cancer Prev. |
pmid:25169491
|
Saini M et al. |
Trichostatin A alters the expression of cell cycle controlling genes and microRNAs in donor cells and subsequently improves the yield and quality of cloned bovine embryos in vitro. |
2014 |
Theriogenology |
pmid:25151601
|
Tomioka T et al. |
The histone deacetylase inhibitor trichostatin A induces neurite outgrowth in PC12 cells via the epigenetically regulated expression of the nur77 gene. |
2014 |
Neurosci. Res. |
pmid:25128386
|
Zhang Q et al. |
Interferon regulatory factor 8 functions as a tumor suppressor in renal cell carcinoma and its promoter methylation is associated with patient poor prognosis. |
2014 |
Cancer Lett. |
pmid:25109451
|
Helm D et al. |
Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics. |
2014 |
Mol. Cell Proteomics |
pmid:25106551
|
Yoshida T et al. |
Kruppel-like factor 4 protein regulates isoproterenol-induced cardiac hypertrophy by modulating myocardin expression and activity. |
2014 |
J. Biol. Chem. |
pmid:25100730
|
Dubois-Pot-Schneider H et al. |
Inflammatory cytokines promote the retrodifferentiation of tumor-derived hepatocyte-like cells to progenitor cells. |
2014 |
Hepatology |
pmid:25098666
|
Wu TH et al. |
Melatonin prevents neonatal dexamethasone induced programmed hypertension: histone deacetylase inhibition. |
2014 |
J. Steroid Biochem. Mol. Biol. |
pmid:25090636
|
Shi Q et al. |
[Inhibitory effect of trichostatin A on HepG2 cell proliferation and the mechanisms]. |
2014 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:25057056
|
Tsuji M et al. |
Epigenetic regulation of resistance to emotional stress: possible involvement of 5-HT1A receptor-mediated histone acetylation. |
2014 |
J. Pharmacol. Sci. |
pmid:25048113
|
Charni Chaabane S et al. |
PDGF-D expression is down-regulated by TGFβ in fibroblasts. |
2014 |
PLoS ONE |
pmid:25280005
|
Knobloch J et al. |
Resveratrol attenuates the release of inflammatory cytokines from human bronchial smooth muscle cells exposed to lipoteichoic acid in chronic obstructive pulmonary disease. |
2014 |
Basic Clin. Pharmacol. Toxicol. |
pmid:23981542
|
Choi DC et al. |
MicroRNA-7 protects against 1-methyl-4-phenylpyridinium-induced cell death by targeting RelA. |
2014 |
J. Neurosci. |
pmid:25232110
|
Vorrink SU et al. |
Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126). |
2014 |
Int J Mol Sci |
pmid:25116688
|
Scholpa NE et al. |
Epigenetic changes in p21 expression in renal cells after exposure to bromate. |
2014 |
Toxicol. Sci. |
pmid:25015661
|
Bartling TR et al. |
Redox-sensitive gene-regulatory events controlling aberrant matrix metalloproteinase-1 expression. |
2014 |
Free Radic. Biol. Med. |
pmid:24973648
|
Busbee PB et al. |
Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression. |
2014 |
Toxicol. Appl. Pharmacol. |
pmid:24200994
|
Poljak M et al. |
Class I to III histone deacetylases differentially regulate inflammation-induced matrix metalloproteinase 9 expression in primary amnion cells. |
2014 |
Reprod Sci |
pmid:24429678
|
Shin HJ et al. |
Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation. |
2014 |
J. Virol. |
pmid:24227836
|
Unland R et al. |
Epigenetic repression of the dopamine receptor D4 in pediatric tumors of the central nervous system. |
2014 |
J. Neurooncol. |
pmid:24264533
|
Yang DH et al. |
Dynamic rearrangement of F-actin is required to maintain the antitumor effect of trichostatin A. |
2014 |
PLoS ONE |
pmid:24846135
|
Sun DF et al. |
Inhibition of mTOR signalling potentiates the effects of trichostatin A in human gastric cancer cell lines by promoting histone acetylation. |
2014 |
Cell Biol. Int. |
pmid:24030871
|
Kumafuji M et al. |
Mediator MED18 subunit plays a negative role in transcription via the CDK/cyclin module. |
2014 |
Genes Cells |
pmid:24840924
|
Skoge RH et al. |
Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels. |
2014 |
DNA Repair (Amst.) |
pmid:24814981
|
Smirnova L et al. |
MicroRNA profiling as tool for in vitro developmental neurotoxicity testing: the case of sodium valproate. |
2014 |
PLoS ONE |
pmid:24896083
|
Meier BC and Wagner BK |
Inhibition of HDAC3 as a strategy for developing novel diabetes therapeutics. |
2014 |
Epigenomics |
pmid:24811789
|
Motevalli A et al. |
The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines. |
2014 |
Breast Cancer Res. Treat. |
pmid:24807106
|
Guo W et al. |
Aberrant methylation and decreased expression of the TGF-β/Smad target gene FBXO32 in esophageal squamous cell carcinoma. |
2014 |
Cancer |
pmid:24798237
|
Palii CG et al. |
Trichostatin A enhances vascular repair by injected human endothelial progenitors through increasing the expression of TAL1-dependent genes. |
2014 |
Cell Stem Cell |
pmid:24792117
|
Soler E and Grosveld F |
Targeting epigenetics to speed up repair. |
2014 |
Cell Stem Cell |
pmid:24792110
|
Poplutz MK et al. |
Regulation of the Interleukin-6 gene expression during monocytic differentiation of HL-60 cells by chromatin remodeling and methylation. |
2014 |
Immunobiology |
pmid:24746556
|
Rafehi H et al. |
Vascular histone deacetylation by pharmacological HDAC inhibition. |
2014 |
Genome Res. |
pmid:24732587
|
Deng Y et al. |
[Expression of neprilysin gene is associated with methylation and histone modification on promoter in mouse neuroblastoma Neuro-2a cells]. |
2014 |
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi |
pmid:25108432
|
Fang J et al. |
Epigenetic modulation of neuronal apoptosis and cognitive functions in sepsis-associated encephalopathy. |
2014 |
Neurol. Sci. |
pmid:23925573
|
Xie L et al. |
Histone deacetylase inhibitors trichostatin A and vorinostat inhibit TGFβ2-induced lens epithelial-to-mesenchymal cell transition. |
2014 |
Invest. Ophthalmol. Vis. Sci. |
pmid:24994865
|
Michalak P |
Evidence for maternal imprinting of 45S ribosomal RNA genes in Xenopus hybrids. |
2014 |
Dev. Genes Evol. |
pmid:24477594
|
Uhlenbrock F et al. |
The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway. |
2014 |
J. Immunol. |
pmid:25024379
|
Sassi Fde A et al. |
Inhibitory activities of trichostatin a in U87 glioblastoma cells and tumorsphere-derived cells. |
2014 |
J. Mol. Neurosci. |
pmid:24464841
|
Li H et al. |
The histone deacetylase inhibitor trichostatin a promotes totipotency in the male gametophyte. |
2014 |
Plant Cell |
pmid:24464291
|
Xiao W et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial-mesenchymal transition in retinal pigment epithelium cells. |
2014 |
J. Cell. Mol. Med. |
pmid:24456602
|
Oride A et al. |
Trichostatin A specifically stimulates gonadotropin FSHβ gene expression in gonadotroph LβT2 cells. |
2014 |
Endocr. J. |
pmid:24430728
|
Sugimoto K et al. |
Improving allogeneic islet transplantation by suppressing Th17 and enhancing Treg with histone deacetylase inhibitors. |
2014 |
Transpl. Int. |
pmid:24410777
|
Zhu M et al. |
Histone decacetylase inhibitors prevent mitochondrial fragmentation and elicit early neuroprotection against MPP+. |
2014 |
CNS Neurosci Ther |
pmid:24351065
|
Xu S et al. |
Cytostatic and apoptotic effects of DNMT and HDAC inhibitors in endometrial cancer cells. |
2014 |
Curr. Pharm. Des. |
pmid:23888960
|
Liu J et al. |
DNA promoter and histone H3 methylation downregulate NGX6 in gastric cancer cells. |
2014 |
Med. Oncol. |
pmid:24338274
|
Al-Rayyan N et al. |
5-Aza-2-deoxycytidine and trichostatin A increase COUP-TFII expression in antiestrogen-resistant breast cancer cell lines. |
2014 |
Cancer Lett. |
pmid:24513177
|
Yang W et al. |
Trichostatin A increases the levels of plasma gelsolin and amyloid beta-protein in a transgenic mouse model of Alzheimer's disease. |
2014 |
Life Sci. |
pmid:24486299
|
Brglez V et al. |
Secreted phospholipases Aâ‚‚are differentially expressed and epigenetically silenced in human breast cancer cells. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:24508801
|
Smith S et al. |
Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity. |
2014 |
PLoS ONE |
pmid:24466340
|
Chen HY et al. |
Histone deacetylase inhibitors trichostatin A and suberoylanilide hydroxamic acid attenuate ventilator-induced lung injury. |
2014 |
Pharmazie |
pmid:24601225
|
Kilinc V et al. |
Do iron chelators increase the antiproliferative effect of trichostatin A through a glucose-regulated protein 78 mediated mechanism? |
2014 |
Tumour Biol. |
pmid:24622883
|
Bezecny P |
Histone deacetylase inhibitors in glioblastoma: pre-clinical and clinical experience. |
2014 |
Med. Oncol. |
pmid:24838514
|
Kizuka Y et al. |
Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers. |
2014 |
J. Biol. Chem. |
pmid:24619417
|
Kumar P et al. |
Histone deacetylase inhibitors modulate the transcriptional regulation of guanylyl cyclase/natriuretic peptide receptor-a gene: interactive roles of modified histones, histone acetyltransferase, p300, AND Sp1. |
2014 |
J. Biol. Chem. |
pmid:24451378
|
Sathe A et al. |
MicroRNA let-7f: a novel regulator of innate immune response in human endocervical cells. |
2014 |
Am. J. Reprod. Immunol. |
pmid:24405266
|
Varol N et al. |
The epigenetically regulated effects of Wnt antagonists on the expression of genes in the apoptosis pathway in human bladder cancer cell line (T24). |
2014 |
DNA Cell Biol. |
pmid:24665856
|
Kondo Y et al. |
Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. |
2014 |
PLoS ONE |
pmid:25084468
|
Wisnieski F et al. |
Differential expression of histone deacetylase and acetyltransferase genes in gastric cancer and their modulation by trichostatin A. |
2014 |
Tumour Biol. |
pmid:24668547
|
Yan YE et al. |
Prenatal nicotinic exposure suppresses fetal adrenal steroidogenesis via steroidogenic factor 1 (SF-1) deacetylation. |
2014 |
Toxicol. Appl. Pharmacol. |
pmid:24709674
|
Karki P et al. |
Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. |
2014 |
Mol. Cell. Biol. |
pmid:24469401
|
Alsarraf O et al. |
Acetylation: a lysine modification with neuroprotective effects in ischemic retinal degeneration. |
2014 |
Exp. Eye Res. |
pmid:25064603
|
Kanski R et al. |
Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network. |
2014 |
J. Cell. Sci. |
pmid:25128567
|
Hennig D et al. |
Novel insights into appropriate encapsulation methods for bioactive compounds into polymers: a study with peptides and HDAC inhibitors. |
2014 |
Macromol Biosci |
pmid:23966296
|
Mahmud N et al. |
Differential effects of epigenetic modifiers on the expansion and maintenance of human cord blood stem/progenitor cells. |
2014 |
Biol. Blood Marrow Transplant. |
pmid:24374212
|
Holownia A et al. |
Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1. |
2014 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:24287576
|
Green BB and Kerr DE |
Epigenetic contribution to individual variation in response to lipopolysaccharide in bovine dermal fibroblasts. |
2014 |
Vet. Immunol. Immunopathol. |
pmid:24268632
|