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Haploinsufficient prostate tumor suppression by Nkx3.1: a role for chromatin accessibility in dosage-sensitive gene regulation. |
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Inhibition of trichostatin A-induced antiangiogenesis by small-interfering RNA for thrombospondin-1. |
2007 |
Exp. Mol. Med. |
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CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A. |
2007 |
Neoplasia |
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Requirement of histone deacetylase activity for the expression of critical photoreceptor genes. |
2007 |
BMC Dev. Biol. |
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Histone deacetylase 4 is required for TGFbeta1-induced myofibroblastic differentiation. |
2007 |
Biochim. Biophys. Acta |
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Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica. |
2007 |
BMC Genomics |
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The HDAC inhibitor trichostatin A inhibits growth of small cell lung cancer cells. |
2007 |
J. Surg. Res. |
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Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression. |
2007 |
Biochem. Cell Biol. |
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Effects of chromatin-modifying agents on CD34+ cells from patients with idiopathic myelofibrosis. |
2007 |
Cancer Res. |
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A functional link between rhythmic changes in chromatin structure and the Arabidopsis biological clock. |
2007 |
Plant Cell |
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Roles of histone acetylation modification in basal and inducible expression of hsp26 gene in D. melanogaster. |
2007 |
Mol. Cell. Biochem. |
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Design, synthesis and biological evaluation of 1,4-benzodiazepine-2,5-dione-based HDAC inhibitors. |
2007 |
Bioorg. Med. Chem. Lett. |
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Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells. |
2007 |
Leukemia |
pmid:17625602
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Bu Y and Gelman IH |
v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex. |
2007 |
J. Biol. Chem. |
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Steroids and histone deacetylase in ventilation-induced gene transcription. |
2007 |
Eur. Respir. J. |
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Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-alpha is rescued by HDAC inhibitor trichostatin A. |
2007 |
Am. J. Physiol., Cell Physiol. |
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Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro. |
2007 |
J. Parasitol. |
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Acetylation of histone H3 and adrenergic-regulated gene transcription in rat pinealocytes. |
2007 |
Endocrinology |
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HDAC3 is linked to cell cycle machinery in MiaPaCa2 cells by regulating transcription of skp2. |
2007 |
Cell Prolif. |
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Bode KA et al. |
Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. |
2007 |
Immunology |
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Inhibition of histone deacetylase activates side population cells in kidney and partially reverses chronic renal injury. |
2007 |
Stem Cells |
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Global epiproteomic signatures distinguish embryonic stem cells from differentiated cells. |
2007 |
Stem Cells |
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Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. |
2007 |
Nat. Chem. Biol. |
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Splicing factor SF3b as a target of the antitumor natural product pladienolide. |
2007 |
Nat. Chem. Biol. |
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BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3. |
2007 |
J. Biol. Chem. |
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Trichostatin A, a histone deacetylase inhibitor, attenuates invasiveness and reactivates E-cadherin expression in immortalized endometriotic cells. |
2007 |
Reprod Sci |
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[Experimental study on the effect of trichostatin A on differentiation of human lung carcinoma cell]. |
2007 |
Zhonghua Yi Xue Za Zhi |
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Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis. |
2008 |
Oncogene |
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The histone deacetylase inhibitor sodium butyrate inhibits baculovirus-mediated transgene expression in Sf9 cells. |
2007 |
J. Biotechnol. |
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Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells. |
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Pharm. Res. |
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[Impact of trichostatin A on gastric carcinoma cell line SGC-7901]. |
2007 |
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The zinc finger repressor, ZBP-89, recruits histone deacetylase 1 to repress vimentin gene expression. |
2007 |
Genes Cells |
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Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis. |
2007 |
Arthritis Rheum. |
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The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model. |
2007 |
Br. J. Cancer |
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Inhibition of telomerase activity and human telomerase reverse transcriptase gene expression by histone deacetylase inhibitor in human brain cancer cells. |
2007 |
Mutat. Res. |
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Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2. |
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Biochim. Biophys. Acta |
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The combination of the histone-deacetylase inhibitor trichostatin A and gemcitabine induces inhibition of proliferation and increased apoptosis in pancreatic carcinoma cells. |
2007 |
Int. J. Oncol. |
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Epigenetic regulation of CD20 protein expression in a novel B-cell lymphoma cell line, RRBL1, established from a patient treated repeatedly with rituximab-containing chemotherapy. |
2007 |
Int. J. Hematol. |
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Histone deacetylase inhibitors suppress TF-kappaB-dependent agonist-driven tissue factor expression in endothelial cells and monocytes. |
2007 |
J. Biol. Chem. |
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The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake. |
2007 |
Cancer Biother. Radiopharm. |
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Telomerase expression and cell proliferation in ovarian cancer cells induced by histone deacetylase inhibitors. |
2008 |
Arch. Gynecol. Obstet. |
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[The relationship of mTOR signaling pathway and histone acetylation in human gastric cancer cell lines]. |
2007 |
Zhonghua Yi Xue Yi Chuan Xue Za Zhi |
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The interferon-alpha responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma. |
2007 |
Cancer Genet. Cytogenet. |
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Class II-selective histone deacetylase inhibitors. Part 2: alignment-independent GRIND 3-D QSAR, homology and docking studies. |
2008 |
Eur J Med Chem |
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Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. |
2007 |
Blood |
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Differential regulation of thrombospondin-1 expression and antiangiogenesis of ECV304 cells by trichostatin A and helixor A. |
2007 |
Anticancer Drugs |
pmid:17704650
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Byers J and Eichinger D |
Acetylation of the Entamoeba histone H4 N-terminal domain is influenced by short-chain fatty acids that enter trophozoites in a pH-dependent manner. |
2008 |
Int. J. Parasitol. |
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Insulin-like Growth Factor Binding Protein-3 expression in the human corneal epithelium. |
2007 |
Exp. Eye Res. |
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Histone deacetylase inhibitors reduce steroidogenesis through SCF-mediated ubiquitination and degradation of steroidogenic factor 1 (NR5A1). |
2007 |
Mol. Cell. Biol. |
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Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes. |
2007 |
Mol. Cell. Biol. |
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Suppression of lipopolysaccharide- and tumour necrosis factor-alpha-induced interleukin (IL)-8 expression by glucocorticoids involves changes in IL-8 promoter acetylation. |
2007 |
Clin. Exp. Immunol. |
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Histone deacetylase inhibitors preferentially augment transient transgene expression in human dermal fibroblasts. |
2007 |
Br. J. Dermatol. |
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Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. |
2007 |
PLoS ONE |
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Adcock IM et al. |
Epigenetic regulation of airway inflammation. |
2007 |
Curr. Opin. Immunol. |
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Attenuated DNA damage repair by trichostatin A through BRCA1 suppression. |
2007 |
Radiat. Res. |
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The histone deacetylase inhibitor trichostatin A induces GADD45 gamma expression via Oct and NF-Y binding sites. |
2008 |
Oncogene |
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Manning J et al. |
Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours. |
2008 |
Immunology |
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Site-specific acetylation of ISWI by GCN5. |
2007 |
BMC Mol. Biol. |
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Dynamic reprogramming of histone acetylation and methylation in the first cell cycle of cloned mouse embryos. |
2007 |
Biol. Reprod. |
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TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
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Spatial distribution of histone methylation during MHC class II expression. |
2008 |
Mol. Immunol. |
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Relaxed repression of herpes simplex virus type 1 genomes in Murine trigeminal neurons. |
2007 |
J. Virol. |
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Trichostatin-A induces differential changes in histone protein dynamics and expression in HeLa cells. |
2007 |
Biochem. Biophys. Res. Commun. |
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Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion. |
2007 |
J. Biol. Chem. |
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Molecular design of histone deacetylase inhibitors by aromatic ring shifting in chlamydocin framework. |
2007 |
Bioorg. Med. Chem. |
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Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury. |
2007 |
Cardiovasc. Res. |
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Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR. |
2008 |
Breast Cancer Res. Treat. |
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[Role of human telomerase reverse transcriptase in apoptosis of human umbilical vein endothelial cells induced by trichostatin A]. |
2007 |
Zhonghua Zhong Liu Za Zhi |
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Downregulation of microRNAs-143 and -145 in B-cell malignancies. |
2007 |
Cancer Sci. |
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Global chromatin compaction limits the strength of the DNA damage response. |
2007 |
J. Cell Biol. |
pmid:17893239
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The histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes. |
2007 |
Biochim. Biophys. Acta |
pmid:17894944
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Papillomavirus binding factor binds to SAP30 and represses transcription via recruitment of the HDAC1 co-repressor complex. |
2007 |
Arch. Biochem. Biophys. |
pmid:17897615
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Antiproliferative activities of a library of hybrids between indanones and HDAC inhibitor SAHA and MS-275 analogues. |
2007 |
Bioorg. Med. Chem. Lett. |
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Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides. |
2008 |
Bioorg. Med. Chem. |
pmid:17900911
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Lattal KM et al. |
Systemic or intrahippocampal delivery of histone deacetylase inhibitors facilitates fear extinction. |
2007 |
Behav. Neurosci. |
pmid:17907845
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Zhang Y et al. |
An epigenetic modifier results in improved in vitro blastocyst production after somatic cell nuclear transfer. |
2007 |
Cloning Stem Cells |
pmid:17907946
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Noro R et al. |
PTEN inactivation in lung cancer cells and the effect of its recovery on treatment with epidermal growth factor receptor tyrosine kinase inhibitors. |
2007 |
Int. J. Oncol. |
pmid:17912443
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Hämäläinen M et al. |
Inhibition of iNOS expression and NO production by anti-inflammatory steroids. Reversal by histone deacetylase inhibitors. |
2008 |
Pulm Pharmacol Ther |
pmid:17913526
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Li T and Chiang JY |
A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene. |
2007 |
Gastroenterology |
pmid:17920062
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Tao R et al. |
Deacetylase inhibition promotes the generation and function of regulatory T cells. |
2007 |
Nat. Med. |
pmid:17922010
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Qi J et al. |
[The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. |
2007 |
Zhonghua Yi Xue Za Zhi |
pmid:17923031
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Pulukuri SM et al. |
Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator. |
2007 |
J. Biol. Chem. |
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Itoh Y et al. |
Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. |
2007 |
J. Med. Chem. |
pmid:17929798
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Pluemsampant S et al. |
Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors. |
2008 |
Int. J. Cancer |
pmid:17935135
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Pourebrahim R et al. |
ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations. |
2007 |
FEBS Lett. |
pmid:17936758
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Carén H et al. |
Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours. |
2007 |
Br. J. Cancer |
pmid:17940511
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Schauber J et al. |
Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. |
2008 |
J. Invest. Dermatol. |
pmid:17943182
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Oshima M et al. |
Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17949687
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Kuljaca S et al. |
Enhancing the anti-angiogenic action of histone deacetylase inhibitors. |
2007 |
Mol. Cancer |
pmid:17958916
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Chen J et al. |
Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis. |
2008 |
Chem. Biol. Interact. |
pmid:17961528
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Kim EJ et al. |
Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. |
2007 |
Mol. Cell |
pmid:17964266
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Shen L et al. |
Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. |
2007 |
PLoS Genet. |
pmid:17967063
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Putnik J et al. |
The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60. |
2007 |
Biochim. Biophys. Acta |
pmid:17980166
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Su RC et al. |
Epigenetic regulation of established human type 1 versus type 2 cytokine responses. |
2008 |
J. Allergy Clin. Immunol. |
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Stapnes C et al. |
Functional characteristics and gene expression profiles of primary acute myeloid leukaemia cells identify patient subgroups that differ in susceptibility to histone deacetylase inhibitors. |
2007 |
Int. J. Oncol. |
pmid:17982680
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Honda H et al. |
Regulation of the CLDN3 gene in ovarian cancer cells. |
2007 |
Cancer Biol. Ther. |
pmid:17986852
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Renthal W et al. |
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. |
2007 |
Neuron |
pmid:17988634
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Gan Y et al. |
Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:17996726
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Ramirez T et al. |
Sodium arsenite modulates histone acetylation, histone deacetylase activity and HMGN protein dynamics in human cells. |
2008 |
Chromosoma |
pmid:17999076
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Malinen M et al. |
Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to Trichostatin A and 1alpha,25-dihydroxyvitamin D3. |
2008 |
Nucleic Acids Res. |
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