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Alleviation of osteoarthritis by Trichostatin A, a histone deacetylase inhibitor, in experimental osteoarthritis. |
2010 |
Mol. Biol. Rep. |
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Urbinati G et al. |
Liposomes loaded with histone deacetylase inhibitors for breast cancer therapy. |
2010 |
Int J Pharm |
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Sharma P et al. |
Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells. |
2010 |
Mol. Cancer |
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Repouskou A et al. |
The circadian expression of c-MYC is modulated by the histone deacetylase inhibitor trichostatin A in synchronized murine neuroblastoma cells. |
2010 |
Chronobiol. Int. |
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Tessema M et al. |
Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis. |
2010 |
Oncogene |
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Kashiwagi Y et al. |
Trichostatin A-induced TGF-beta type II receptor expression in retinoblastoma cell lines. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
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Kaimori A et al. |
Histone deacetylase inhibition suppresses the transforming growth factor beta1-induced epithelial-to-mesenchymal transition in hepatocytes. |
2010 |
Hepatology |
pmid:20564330
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Awe S and Renkawitz-Pohl R |
Histone H4 acetylation is essential to proceed from a histone- to a protamine-based chromatin structure in spermatid nuclei of Drosophila melanogaster. |
2010 |
Syst Biol Reprod Med |
pmid:20170286
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Jichan Nie SW et al. |
Promoter hypermethylation of progesterone receptor isoform B (PR-B) in adenomyosis and its rectification by a histone deacetylase inhibitor and a demethylation agent. |
2010 |
Reprod Sci |
pmid:20697142
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Akiba Y et al. |
Histone deacetylase inhibitors de-repress tyrosine hydroxylase expression in the olfactory bulb and rostral migratory stream. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20170631
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Costa-Borges N et al. |
Comparison between the effects of valproic acid and trichostatin A on the in vitro development, blastocyst quality, and full-term development of mouse somatic cell nuclear transfer embryos. |
2010 |
Cell Reprogram |
pmid:20698782
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Angst E et al. |
Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells. |
2010 |
Pancreas |
pmid:20173668
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Lee HS et al. |
Enhanced histone acetylation in somatic cells induced by a histone deacetylase inhibitor improved inter-generic cloned leopard cat blastocysts. |
2010 |
Theriogenology |
pmid:20708232
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Zhang L et al. |
Histone deacetylase inhibitors attenuate acute lung injury during cecal ligation and puncture-induced polymicrobial sepsis. |
2010 |
World J Surg |
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Tokoro M et al. |
Deposition of acetylated histones by RNAP II promoter clearance may occur at onset of zygotic gene activation in preimplantation mouse embryos. |
2010 |
J. Reprod. Dev. |
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Peng CY et al. |
Growth-inhibiting effects of arsenic trioxide plus epigenetic therapeutic agents on leukemia cell lines. |
2010 |
Leuk. Lymphoma |
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Li RJ et al. |
Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance. |
2010 |
Ann. Oncol. |
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Nordén R et al. |
Inhibition of protein deacetylation augments herpes simplex virus type 1-activated transcription of host fucosyltransferase genes associated with virus-induced sLex expression. |
2010 |
Arch. Virol. |
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Wang X et al. |
Sequential treatment of CD34+ cells from patients with primary myelofibrosis with chromatin-modifying agents eliminate JAK2V617F-positive NOD/SCID marrow repopulating cells. |
2010 |
Blood |
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[Cellular aspects of regulation of nuclear factor kappaB (NF-kappabeta) transcriptional activity in sensory neurons in vitro]. |
2010 |
Morfologiia |
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HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability. |
2010 |
Oncogene |
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Histone H1 subtype preferences of DFF40 and possible nuclear localization of DFF40/45 in normal and trichostatin A-treated NB4 leukemic cells. |
2010 |
Apoptosis |
pmid:19882353
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Hui KF and Chiang AK |
Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein-Barr virus-positive epithelial malignancies and mediates enhanced cell death. |
2010 |
Int. J. Cancer |
pmid:19816947
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Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation. |
2009 May-Jun |
Photochem. Photobiol. |
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BCL11A represses HBG transcription in K562 cells. |
2009 Mar-Apr |
Blood Cells Mol. Dis. |
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Using histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance. |
2009 Mar-Apr |
Immunol. Cell Biol. |
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Endothelin-1 reverses the histone deacetylase inhibitor-induced increase in glial glutamate transporter transcription without affecting histone acetylation levels. |
2009 Jul-Aug |
Neurochem. Int. |
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Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. |
2009 |
Proteomics |
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Enhancement of histone acetylation by trichostatin A during in vitro fertilization of bovine oocytes affects cell number of the inner cell mass of the resulting blastocysts. |
2009 |
Zygote |
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Morita K et al. |
Histone deacetylase inhibitors promote neurosteroid-mediated cell differentiation and enhance serotonin-stimulated brain-derived neurotrophic factor gene expression in rat C6 glioma cells. |
2009 |
J. Neurosci. Res. |
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von Burstin J et al. |
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. |
2009 |
Gastroenterology |
pmid:19362090
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Yang X et al. |
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. |
2009 |
PLoS ONE |
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Epigenetic influences on sensory regeneration: histone deacetylases regulate supporting cell proliferation in the avian utricle. |
2009 |
J. Assoc. Res. Otolaryngol. |
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Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. |
2009 |
Clin. Cancer Res. |
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Lu SC et al. |
The essential role of Oct-2 in LPS-induced expression of iNOS in RAW 264.7 macrophages and its regulation by trichostatin A. |
2009 |
Am. J. Physiol., Cell Physiol. |
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Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells. |
2009 |
Toxicol. Appl. Pharmacol. |
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N-Hydroxy-(4-oxime)-cinnamide: a versatile scaffold for the synthesis of novel histone deacetylase [correction of deacetilase] (HDAC) inhibitors. |
2009 |
Bioorg. Med. Chem. Lett. |
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[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells]. |
2009 |
Zhonghua Wei Chang Wai Ke Za Zhi |
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Conserved responses to trichostatin A in rodent lungs exposed to endotoxin or stretch. |
2009 |
Pulm Pharmacol Ther |
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Dandrea M et al. |
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines. |
2009 |
Nucleic Acids Res. |
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Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation. |
2009 |
Biochim. Biophys. Acta |
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Trichostatin A affects histone acetylation and gene expression in porcine somatic cell nucleus transfer embryos. |
2009 |
Theriogenology |
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Demonstration of all-or-none loss of imprinting in mRNA expression in single cells. |
2009 |
Nucleic Acids Res. |
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Histone deacetylase inhibitor trichostatin A modulates cell cycles in A2780 human ovarian cancer cell lines. |
2009 |
Eur. J. Gynaecol. Oncol. |
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Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition. |
2009 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
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Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea. |
2009 |
J. Neurochem. |
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Zhao W et al. |
Histone deacetylase inhibitor, trichostatin A, affects gene expression patterns during morphogenesis of chicken limb buds in vivo. |
2009 |
Cells Tissues Organs (Print) |
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Tubulin acetylation favors Hsp90 recruitment to microtubules and stimulates the signaling function of the Hsp90 clients Akt/PKB and p53. |
2009 |
Cell. Signal. |
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3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment. |
2009 |
Eur J Med Chem |
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Cowell RM et al. |
Identification of novel targets for PGC-1alpha and histone deacetylase inhibitors in neuroblastoma cells. |
2009 |
Biochem. Biophys. Res. Commun. |
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Wiesen JL and Tomasi TB |
Dicer is regulated by cellular stresses and interferons. |
2009 |
Mol. Immunol. |
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Togi S et al. |
HDAC3 influences phosphorylation of STAT3 at serine 727 by interacting with PP2A. |
2009 |
Biochem. Biophys. Res. Commun. |
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Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. |
2009 |
Arterioscler. Thromb. Vasc. Biol. |
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Mavis CK et al. |
Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors. |
2009 |
Prostate |
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The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation. |
2009 |
Free Radic. Biol. Med. |
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Gavin DP et al. |
Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. |
2009 |
J Psychiatry Neurosci |
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Histone acetylation characterizes chromatin presetting by NF1 and Oct1 and enhances glucocorticoid receptor binding to the MMTV promoter. |
2009 |
Exp. Cell Res. |
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Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases. |
2009 |
Bioorg. Med. Chem. Lett. |
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Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. |
2009 |
Clin. Cancer Res. |
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Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes. |
2009 |
Clin. Cancer Res. |
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Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression. |
2009 |
BMC Cancer |
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Histone deacetylase inhibition improves meiotic competence but not developmental competence in growing pig oocytes. |
2009 |
Zygote |
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Dubois F et al. |
Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni. |
2009 |
Mol. Biochem. Parasitol. |
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[Construction of anti-sense cDNA library of human breast cancer cells during apoptosis induced by trichostatin A and preliminary screening of essential genes]. |
2009 |
Zhonghua Yi Xue Za Zhi |
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Use of epigenetic modification to induce FOXP3 expression in naïve T cells. |
2009 |
Transplant. Proc. |
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15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. |
2009 |
Clin. Cancer Res. |
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Rahim R and Strobl JS |
Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells. |
2009 |
Anticancer Drugs |
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Nadasi E et al. |
Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells. |
2009 |
Anticancer Res. |
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Basal endothelial nitric oxide synthase (eNOS) phosphorylation on Ser(1177) occurs in a stable microtubule- and tubulin acetylation-dependent manner. |
2009 |
Exp. Cell Res. |
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The improvement of adenovirus vector production by increased expression of coxsackie adenovirus receptor. |
2009 |
Biotechnol. Lett. |
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Hollosi P et al. |
Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells. |
2009 |
Int. J. Cancer |
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Chen J et al. |
E1A has no effect on LPS-induced IL-6 secretion in rat alveolar epithelial cells. |
2009 |
Respiration |
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Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. |
2009 |
Nat. Chem. Biol. |
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Effect of trychostatin A treatment on gene expression in cloned mouse embryos. |
2009 |
Theriogenology |
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Cunneen TS et al. |
In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells. |
2009 |
Arch. Ophthalmol. |
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Synthesis and modeling of new benzofuranone histone deacetylase inhibitors that stimulate tumor suppressor gene expression. |
2009 |
J. Med. Chem. |
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Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells. |
2009 |
Anticancer Res. |
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Åuczak MW and JagodziÅ„ski PP |
Trichostatin A down-regulates CYP19 transcript and protein levels in MCF-7 breast cancer cells. |
2009 |
Biomed. Pharmacother. |
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Puca R et al. |
HIPK2 modulates p53 activity towards pro-apoptotic transcription. |
2009 |
Mol. Cancer |
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Röhrs S et al. |
Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia. |
2009 |
Mol. Cancer |
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HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. |
2009 |
Neurosci. Lett. |
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Mastitskaya S and Denecke B |
Human spongiosa mesenchymal stem cells fail to generate cardiomyocytes in vitro. |
2009 |
J Negat Results Biomed |
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Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells. |
2009 |
Mol. Cancer Ther. |
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Koh HS et al. |
Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells. |
2009 |
Mol. Cells |
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Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. |
2009 |
Breast Cancer Res. Treat. |
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Sharma A et al. |
Trichostatin a inhibits corneal haze in vitro and in vivo. |
2009 |
Invest. Ophthalmol. Vis. Sci. |
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Zubia A et al. |
Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity. |
2009 |
Oncogene |
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Meng Q et al. |
Live birth of somatic cell-cloned rabbits following trichostatin A treatment and cotransfer of parthenogenetic embryos. |
2009 |
Cloning Stem Cells |
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Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications. |
2009 |
Eur. J. Cancer |
pmid:19818596
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Zhang F et al. |
Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells. |
2009 |
Cancer Biol. Ther. |
pmid:19270532
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Hara D et al. |
Persistent BDNF exon I-IX mRNA expression following the withdrawal of neuronal activity in neurons. |
2009 |
Biochem. Biophys. Res. Commun. |
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Tan HH and Porter AG |
p21(WAF1) negatively regulates DNMT1 expression in mammalian cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19275888
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Li C et al. |
Induction of myelogenous leukemia cells with histone deacetylase inhibitors through down-regulating the Daxx protein expression. |
2009 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
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Gavin DP et al. |
Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population. |
2009 |
J Psychiatr Res |
pmid:19187942
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Liberatore RA et al. |
NF-kappaB activity is constitutively elevated in c-Abl null fibroblasts. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805123
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Sasaki K et al. |
Real-time imaging of histone H4 hyperacetylation in living cells. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805290
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Gibbs A et al. |
Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805354
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Popova EY et al. |
Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. |
2009 |
Chromosome Res. |
pmid:19172406
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Tsuji Y et al. |
The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2'-deoxycytidine. |
2009 |
Zygote |
pmid:19175955
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Lee JH et al. |
Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway. |
2009 |
Mol. Cancer Res. |
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