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The mouse tumor cell lines EL4 and RMA display mosaic expression of NK-related and certain other surface molecules and appear to have a common origin. |
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IGF-II and IL-2 act synergistically to alter HDAC1 expression following treatments with trichostatin a. |
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Cytokine |
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Cancer Res. |
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Cancer Res. |
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A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
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Mao C and Shapiro DJ |
A histone deacetylase inhibitor potentiates estrogen receptor activation of a stably integrated vitellogenin promoter in HepG2 cells. |
2000 |
Endocrinology |
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BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. |
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Mol. Cell. Biol. |
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Endocrinology |
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Improved recombinant retroviral titers utilizing trichostatin A. |
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BioTechniques |
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ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain. |
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Mol. Cell. Biol. |
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Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. |
2001 |
Cancer Chemother. Pharmacol. |
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The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases. |
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Mol. Endocrinol. |
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The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells. |
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Involvement of histone H4 acetylation in the epigenetic inheritance of different activity states of maternally and paternally derived genomes in the mealybug Planococcus citri. |
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Chromosoma |
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Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures. |
2001 |
Haematologica |
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DNA methylation regulates placental lactogen I gene expression. |
2001 |
Endocrinology |
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Trichostatin A inhibits beta-casein expression in mammary epithelial cells. |
2001 |
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2001 |
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Trichostatin A, an inhibitor of histone deacetylase, inhibits hypoxia-induced angiogenesis. |
2001 |
Expert Opin Investig Drugs |
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Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
2001 |
Nucleic Acids Res. |
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Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
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Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells. |
2001 |
Biochem. Pharmacol. |
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Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development. |
2001 |
Zygote |
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Genes modulated by histone acetylation as new effectors of butyrate activity. |
2001 |
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J. Immunol. |
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Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. |
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Mol. Cell. Biol. |
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In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice. |
2001 |
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Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain. |
2001 |
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Cell type-specific roles of histone deacetylase in TR ligand-independent transcriptional repression. |
2001 |
Mol. Cell. Endocrinol. |
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Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity. |
2001 |
Cancer Res. |
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DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. |
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Cancer Res. |
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Loss of PU.1 expression following inhibition of histone deacetylases. |
2001 |
J. Immunol. |
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