Jung M |
Inhibitors of histone deacetylase as new anticancer agents. |
2001 |
Curr. Med. Chem. |
pmid:11562279
|
Ashburner BP et al. |
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. |
2001 |
Mol. Cell. Biol. |
pmid:11564889
|
Sachs LM et al. |
Involvement of histone deacetylase at two distinct steps in gene regulation during intestinal development in Xenopus laevis. |
2001 |
Dev. Dyn. |
pmid:11668605
|
Amann JM et al. |
ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain. |
2001 |
Mol. Cell. Biol. |
pmid:11533236
|
Plant KE et al. |
Intergenic transcription in the human beta-globin gene cluster. |
2001 |
Mol. Cell. Biol. |
pmid:11533239
|
Chen Lf W et al. |
Duration of nuclear NF-kappaB action regulated by reversible acetylation. |
2001 |
Science |
pmid:11533489
|
Vinatzer U et al. |
The leukaemia-associated transcription factors EVI-1 and MDS1/EVI1 repress transcription and interact with histone deacetylase. |
2001 |
Br. J. Haematol. |
pmid:11552981
|
Sekimata M et al. |
Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2. |
2001 |
J. Biol. Chem. |
pmid:11553631
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad. |
2001 |
Brain Tumor Pathol |
pmid:11908866
|
Benjamin D and Jost JP |
Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
2001 |
Nucleic Acids Res. |
pmid:11522830
|
Seth KA and Majzoub JA |
Repressor element silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) can act as an enhancer as well as a repressor of corticotropin-releasing hormone gene transcription. |
2001 |
J. Biol. Chem. |
pmid:11278361
|
Matsuda E et al. |
Targeting of Krüppel-associated box-containing zinc finger proteins to centromeric heterochromatin. Implication for the gene silencing mechanisms. |
2001 |
J. Biol. Chem. |
pmid:11278721
|
Kim MS et al. |
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. |
2001 |
Nat. Med. |
pmid:11283670
|
Vigushin DM et al. |
Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo. |
2001 |
Clin. Cancer Res. |
pmid:11309348
|
Magdinier F and Wolffe AP |
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11309512
|
Grande A et al. |
A functionally active RARalpha nuclear receptor is expressed in retinoic acid non responsive early myeloblastic cell lines. |
2001 |
Cell Death Differ. |
pmid:11313705
|
Wu Y et al. |
Negative regulation of bcl-2 expression by p53 in hematopoietic cells. |
2001 |
Oncogene |
pmid:11313951
|
Greenberg VL et al. |
Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells. |
2001 |
Thyroid |
pmid:11349829
|
Lea MA et al. |
Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate. |
2001 |
Int. J. Cancer |
pmid:11351296
|
Rashid SF et al. |
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. |
2001 |
Oncogene |
pmid:11313934
|
Osborne A et al. |
Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. |
2001 |
Mol. Cell. Biol. |
pmid:11533238
|
Arthur JL et al. |
Herpes simplex virus type 1 promoter activity during latency establishment, maintenance, and reactivation in primary dorsal root neurons in vitro. |
2001 |
J. Virol. |
pmid:11264377
|
Kuusisto E et al. |
Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11162503
|
Grandjean V et al. |
Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain. |
2001 |
FEBS Lett. |
pmid:11163765
|
Lizcano F et al. |
Cell type-specific roles of histone deacetylase in TR ligand-independent transcriptional repression. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11165035
|
Nervi C et al. |
Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity. |
2001 |
Cancer Res. |
pmid:11245412
|
Zhu WG et al. |
DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. |
2001 |
Cancer Res. |
pmid:11245429
|
Muth V et al. |
Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription. |
2001 |
EMBO J. |
pmid:11250901
|
Laribee RN and Klemsz MJ |
Loss of PU.1 expression following inhibition of histone deacetylases. |
2001 |
J. Immunol. |
pmid:11673528
|
Rombouts K et al. |
Trichostatin A, lead compound for development of antifibrogenic drugs. |
2001 Jul-Sep |
Acta Gastroenterol. Belg. |
pmid:11680040
|
McGuinness MC et al. |
Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. |
2001 Sep-Oct |
Mol. Genet. Metab. |
pmid:11592822
|
Rombouts K et al. |
Actin filament formation, reorganization and migration are impaired in hepatic stellate cells under influence of trichostatin A, a histone deacetylase inhibitor. |
2002 |
J. Hepatol. |
pmid:12445420
|
Guo WH et al. |
Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor. |
2002 |
Oncogene |
pmid:12447699
|
Marin-Husstege M et al. |
Histone deacetylase activity is necessary for oligodendrocyte lineage progression. |
2002 |
J. Neurosci. |
pmid:12451133
|
Wang ZM et al. |
Trichostatin A inhibits proliferation and induces expression of p21WAF and p27 in human brain tumor cell lines. |
2002 |
Ai Zheng |
pmid:12508652
|
Heltweg B and Jung M |
A microplate reader-based nonisotopic histone deacetylase activity assay. |
2002 |
Anal. Biochem. |
pmid:11878795
|
Kamitani H et al. |
Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced. |
2002 |
Neuro-oncology |
pmid:11916500
|
Kishikawa S et al. |
Roles of histone acetylation in the Dnmt1 gene expression. |
2002 |
Nucleic Acids Res. Suppl. |
pmid:12903179
|
Yu Z et al. |
Histone deacetylases augment cytokine induction of the iNOS gene. |
2002 |
J. Am. Soc. Nephrol. |
pmid:12138131
|
Li J et al. |
Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. |
2002 |
Mol. Cell. Biol. |
pmid:12138181
|
Aapola U et al. |
Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity. |
2002 |
Nucleic Acids Res. |
pmid:12177302
|
Chang TH and Szabo E |
Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. |
2002 |
Clin. Cancer Res. |
pmid:11948134
|
Ventura A et al. |
The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter. |
2002 |
J. Biol. Chem. |
pmid:11948181
|
Wang XQ et al. |
Histone deacetylase inhibition results in decreased macrophage CD9 expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12056820
|
Rahmani M et al. |
The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process. |
2002 |
Exp. Cell Res. |
pmid:12061815
|
Woo SH et al. |
Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors. |
2002 |
J. Med. Chem. |
pmid:12061890
|
Chen Y et al. |
On the epigenetic regulation of the human reelin promoter. |
2002 |
Nucleic Acids Res. |
pmid:12087179
|
Zhang Y and Dufau ML |
Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex. |
2002 |
J. Biol. Chem. |
pmid:12091390
|
Gong XQ and Li L |
Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation. |
2002 |
J. Biol. Chem. |
pmid:11809751
|
Rössig L et al. |
Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis. |
2002 |
Circ. Res. |
pmid:12411399
|