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Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad. |
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Brain Tumor Pathol |
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Targeting of Krüppel-associated box-containing zinc finger proteins to centromeric heterochromatin. Implication for the gene silencing mechanisms. |
2001 |
J. Biol. Chem. |
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2001 |
Nat. Med. |
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Design and synthesis of a novel class of histone deacetylase inhibitors. |
2001 |
Bioorg. Med. Chem. Lett. |
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Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts. |
2001 |
Cell Death Differ. |
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Histone deacetylase activity is required for the induction of the MyoD muscle cell lineage in Xenopus. |
2000 Sep-Oct |
Biol. Chem. |
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Promoter specific sensitivity to inhibition of histone deacetylases: implications for hormonal gene control, cellular differentiation and cancer. |
2000 Mar-Apr |
Anticancer Res. |
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Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor. |
2000 |
J. Biol. Chem. |
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Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. |
2000 |
Cell |
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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. |
2000 |
J. Biol. Chem. |
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The mouse tumor cell lines EL4 and RMA display mosaic expression of NK-related and certain other surface molecules and appear to have a common origin. |
2000 |
J. Immunol. |
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Long-term silencing of retroviral vectors is resistant to reversal by trichostatin A and 5-azacytidine. |
2000 |
Gene Ther. |
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Histone acetylation is a checkpoint in FGF-stimulated mesoderm induction. |
2000 |
Dev. Dyn. |
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IGF-II and IL-2 act synergistically to alter HDAC1 expression following treatments with trichostatin a. |
2000 |
Cytokine |
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A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library. |
2000 |
Cancer Res. |
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2000 |
Cancer Res. |
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Human Slug is a repressor that localizes to sites of active transcription. |
2000 |
Mol. Cell. Biol. |
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BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. |
2000 |
Mol. Cell. Biol. |
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Allele-specific histone acetylation accompanies genomic imprinting of the insulin-like growth factor II receptor gene. |
2000 |
Endocrinology |
pmid:11108251
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Improved recombinant retroviral titers utilizing trichostatin A. |
2000 |
BioTechniques |
pmid:11056820
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