Kikuno N et al. |
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. |
2008 |
Int. J. Cancer |
pmid:18431742
|
Zhang HJ et al. |
Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. |
2008 |
Placenta |
pmid:18440631
|
Xu LN et al. |
Effect of histone deacetylase inhibitor on proliferation of biliary tract cancer cell lines. |
2008 |
World J. Gastroenterol. |
pmid:18442209
|
Yu C et al. |
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. |
2008 |
Neuro-oncology |
pmid:18445700
|
Jensen TJ et al. |
Epigenetic remodeling during arsenical-induced malignant transformation. |
2008 |
Carcinogenesis |
pmid:18448484
|
van West P et al. |
Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. |
2008 |
Microbiology (Reading, Engl.) |
pmid:18451057
|
Geli J et al. |
Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma. |
2008 |
Int. J. Cancer |
pmid:18452173
|
Moynihan AT et al. |
Histone deacetylase inhibitors and a functional potent inhibitory effect on human uterine contractility. |
2008 |
Am. J. Obstet. Gynecol. |
pmid:18455134
|
Mackay CL et al. |
Sensitive, specific, and quantitative FTICR mass spectrometry of combinatorial post-translational modifications in intact histone H4. |
2008 |
Anal. Chem. |
pmid:18457408
|
Hishikawa K and Fujita T |
[Kidney regeneration update]. |
2008 |
Nippon Rinsho |
pmid:18464514
|
Dalgard CL et al. |
Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma. |
2008 |
Clin. Cancer Res. |
pmid:18483379
|
Egler V et al. |
Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death. |
2008 |
Clin. Cancer Res. |
pmid:18483381
|
Chu F et al. |
Cellular conditioning with trichostatin A enhances the anti-stress response through up-regulation of HDAC4 and down-regulation of the IGF/Akt pathway. |
2008 |
Aging Cell |
pmid:18489729
|
Chen Y et al. |
A series of potent and selective, triazolylphenyl-based histone deacetylases inhibitors with activity against pancreatic cancer cells and Plasmodium falciparum. |
2008 |
J. Med. Chem. |
pmid:18494463
|
Sun C and Zhou J |
Trichostatin A improves insulin stimulated glucose utilization and insulin signaling transduction through the repression of HDAC2. |
2008 |
Biochem. Pharmacol. |
pmid:18495085
|
Ma P and Schultz RM |
Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos. |
2008 |
Dev. Biol. |
pmid:18501342
|
Cao W et al. |
Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling. |
2008 |
J. Exp. Med. |
pmid:18504304
|
Pan J et al. |
TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells. |
2008 |
Mol. Cancer Res. |
pmid:18505930
|
Hou J et al. |
Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and its relationship with DNA methylation. |
2008 |
BMC Dev. Biol. |
pmid:18507869
|
Chung KS et al. |
Fission yeast-based screening to identify putative HDAC inhibitors using a telomeric reporter strain. |
2008 |
Mol. Cells |
pmid:18525239
|
Makki MS et al. |
TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels. |
2008 |
Nucleic Acids Res. |
pmid:18535006
|
Hoffmann K et al. |
Increase in antiepileptic efficacy during prolonged treatment with valproic acid: role of inhibition of histone deacetylases? |
2008 |
Epilepsy Res. |
pmid:18538545
|
Jiang X et al. |
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. |
2008 |
Cancer Cell |
pmid:18538736
|
Gavin DP et al. |
Reduced baseline acetylated histone 3 levels, and a blunted response to HDAC inhibition in lymphocyte cultures from schizophrenia subjects. |
2008 |
Schizophr. Res. |
pmid:18539439
|
Lecona E et al. |
Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase. |
2008 |
Mol. Cell. Biol. |
pmid:18541673
|
Marengo E et al. |
Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies. |
2008 |
J. Proteome Res. |
pmid:18543959
|
Zhu X et al. |
Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. |
2008 |
J. Clin. Endocrinol. Metab. |
pmid:18544619
|
Gaviraghi M et al. |
Identification of a candidate alternative promoter region of the human Bcl2L11 (Bim) gene. |
2008 |
BMC Mol. Biol. |
pmid:18549468
|
Mühlethaler-Mottet A et al. |
Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells. |
2008 |
Mol. Cancer |
pmid:18549473
|
Kim B et al. |
Clinically relevant concentrations of valproic acid modulate melatonin MT(1) receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18550052
|
Tavera-Mendoza LE et al. |
Incorporation of histone deacetylase inhibition into the structure of a nuclear receptor agonist. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18550844
|
Chan DW et al. |
Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells. |
2008 |
Int. J. Cancer |
pmid:18553387
|
Ding X et al. |
Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A. |
2008 |
Theriogenology |
pmid:18556056
|
Jia J and Chen J |
Histone hyperacetylation is involved in the quercetin-induced human leukemia cell death. |
2008 |
Pharmazie |
pmid:18557424
|
Muscolini M et al. |
Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells. |
2008 |
Mol. Cancer Ther. |
pmid:18566213
|
Bieliauskas AV and Pflum MK |
Isoform-selective histone deacetylase inhibitors. |
2008 |
Chem Soc Rev |
pmid:18568166
|
Li J et al. |
High in vitro development after somatic cell nuclear transfer and trichostatin A treatment of reconstructed porcine embryos. |
2008 |
Theriogenology |
pmid:18573521
|
Liu Z et al. |
Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. |
2008 |
Oncol. Rep. |
pmid:18575731
|
Plouffe D et al. |
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18579783
|
Sun Y et al. |
Modulation of transcription parameters in glucocorticoid receptor-mediated repression. |
2008 |
Mol. Cell. Endocrinol. |
pmid:18583028
|
Ree AH et al. |
HDAC2 deficiency and histone acetylation. |
2008 |
Nat. Genet. |
pmid:18583969
|
Liu Y et al. |
Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines. |
2008 |
Cancer Invest. |
pmid:18584348
|
Kato A et al. |
Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions. |
2008 |
Exp. Cell Res. |
pmid:18588874
|
Chen CJ et al. |
Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18590721
|
Zhang Y et al. |
Unlocking repression of the human luteinizing hormone receptor gene by trichostatin A-induced cell-specific phosphatase release. |
2008 |
J. Biol. Chem. |
pmid:18596044
|
Åuczak MW and JagodziÅ„ski PP |
Trichostatin A down-regulates CYP19 transcript and protein levels in MCF-7 breast cancer cells. |
2009 |
Biomed. Pharmacother. |
pmid:18602794
|
Northrop JK et al. |
Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells. |
2008 |
J. Immunol. |
pmid:18606637
|
Schmeck B et al. |
Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression. |
2008 |
J. Immunol. |
pmid:18606645
|
Miyanaga A et al. |
Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model. |
2008 |
Mol. Cancer Ther. |
pmid:18606719
|
Tischler JL et al. |
Simple inhibitors of histone deacetylase activity that combine features of short-chain fatty acid and hydroxamic acid inhibitors. |
2008 |
J Enzyme Inhib Med Chem |
pmid:18608778
|
Auer D et al. |
Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. |
2009 |
Breast Cancer Res. Treat. |
pmid:18618240
|
Hayakawa F et al. |
Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis. |
2008 |
J. Biol. Chem. |
pmid:18621739
|
Wu JY et al. |
Enhancement of glutamate uptake in 1-methyl-4-phenylpyridinium-treated astrocytes by trichostatin A. |
2008 |
Neuroreport |
pmid:18628666
|
Shakèd M et al. |
Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling. |
2008 |
PLoS ONE |
pmid:18628975
|
Kawamura T et al. |
Inhibitory effects of short-chain fatty acids on matrix metalloproteinase secretion from human colonic subepithelial myofibroblasts. |
2009 |
Dig. Dis. Sci. |
pmid:18629644
|
Fontán-Lozano A et al. |
Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice. |
2008 |
Mol. Cell. Neurosci. |
pmid:18638560
|
Fabre C et al. |
A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts. |
2008 |
Cell Cycle |
pmid:18641459
|
Kozikowski AP et al. |
Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6. |
2008 |
J. Med. Chem. |
pmid:18642892
|
Dow GS et al. |
Antimalarial activity of phenylthiazolyl-bearing hydroxamate-based histone deacetylase inhibitors. |
2008 |
Antimicrob. Agents Chemother. |
pmid:18644969
|
Liu PY et al. |
Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells. |
2008 |
Mol. Cancer Res. |
pmid:18644983
|
Roy S et al. |
Array-based analysis of the effects of trichostatin A and CG-1521 on cell cycle and cell death in LNCaP prostate cancer cells. |
2008 |
Mol. Cancer Ther. |
pmid:18645003
|
Reilly CM et al. |
The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. |
2008 |
J. Autoimmun. |
pmid:18650065
|
Law AY et al. |
Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. |
2008 |
Exp. Cell Res. |
pmid:18652825
|
Nishikiori N et al. |
Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9. |
2008 May-Jun |
Jpn. J. Ophthalmol. |
pmid:18661270
|
Narver HL et al. |
Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition. |
2008 |
Ann. Neurol. |
pmid:18661558
|
Peng DF et al. |
DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. |
2009 |
Gut |
pmid:18664505
|
Yu J et al. |
Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. |
2008 |
Hepatology |
pmid:18666234
|
Lee TB et al. |
Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy. |
2008 |
BMC Gastroenterol |
pmid:18673531
|
Xiang N et al. |
Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells. |
2008 |
Carcinogenesis |
pmid:18676679
|
Duan H et al. |
Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells. |
2008 |
Oncogene |
pmid:18695675
|
Iacobazzi V et al. |
Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18706393
|
Falk M et al. |
Chromatin structure influences the sensitivity of DNA to gamma-radiation. |
2008 |
Biochim. Biophys. Acta |
pmid:18706456
|
Zhang XH et al. |
Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer. |
2008 |
Cancer Biol. Ther. |
pmid:18708766
|
Lu MC et al. |
Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A. |
2009 |
Arch. Toxicol. |
pmid:18709356
|
Yang YN et al. |
[Effects of trichostatin A and paclitaxel on apoptosis and mitochondrial membrane potential of human endometrial carcinoma Ark2 cells]. |
2008 |
Ai Zheng |
pmid:18710614
|
Obrdlik A et al. |
The histone acetyltransferase PCAF associates with actin and hnRNP U for RNA polymerase II transcription. |
2008 |
Mol. Cell. Biol. |
pmid:18710935
|
Haumaitre C et al. |
Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors. |
2008 |
Mol. Cell. Biol. |
pmid:18710955
|
Yang L et al. |
[Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. |
2008 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:18718068
|
Zou XM et al. |
Gastric cancer cell lines induced by trichostatin A. |
2008 |
World J. Gastroenterol. |
pmid:18720545
|
Miyoshi M et al. |
Short-chain fatty acids and trichostatin A alter tight junction permeability in human umbilical vein endothelial cells. |
2008 Nov-Dec |
Nutrition |
pmid:18723323
|
Codd R et al. |
Zn(II)-dependent histone deacetylase inhibitors: suberoylanilide hydroxamic acid and trichostatin A. |
2009 |
Int. J. Biochem. Cell Biol. |
pmid:18725319
|
Kim M et al. |
LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer. |
2008 |
Cancer Res. |
pmid:18757430
|
Ma Y et al. |
Inhibition of protein deacetylation by trichostatin A impairs microtubule-kinetochore attachment. |
2008 |
Cell. Mol. Life Sci. |
pmid:18759129
|
Bosisio D et al. |
Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. |
2008 |
J. Leukoc. Biol. |
pmid:18780875
|
Li M et al. |
Upregulation of human with-no-lysine kinase-4 gene expression by GATA-1 acetylation. |
2009 |
Int. J. Biochem. Cell Biol. |
pmid:18793746
|
Björkman M et al. |
Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer. |
2008 |
Int. J. Cancer |
pmid:18798265
|
Romieu P et al. |
Histone deacetylase inhibitors decrease cocaine but not sucrose self-administration in rats. |
2008 |
J. Neurosci. |
pmid:18799668
|
Yoshioka H et al. |
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. |
2008 |
J. Biol. Chem. |
pmid:18801729
|
Bonazzi VF et al. |
Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma. |
2009 |
Genes Chromosomes Cancer |
pmid:18803327
|
Lee EJ et al. |
Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. |
2008 |
Int. J. Oncol. |
pmid:18813790
|
Van Wagoner DR and Nattel S |
Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy. |
2008 |
J. Mol. Cell. Cardiol. |
pmid:18817781
|
Hoebeeck J et al. |
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. |
2009 |
Cancer Lett. |
pmid:18819746
|
Han JQ et al. |
[Effects of trichostatin A on the interaction between HBx and histone deacetylase protein 1]. |
2008 |
Zhonghua Gan Zang Bing Za Zhi |
pmid:18822204
|
Fraczek J et al. |
Screening of amide analogues of Trichostatin A in cultures of primary rat hepatocytes: search for potent and safe HDAC inhibitors. |
2009 |
Invest New Drugs |
pmid:18825314
|
Pellicciotta I et al. |
Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition. |
2008 |
Cancer Res. |
pmid:18829567
|
Demircan B et al. |
Comparative epigenomics of human and mouse mammary tumors. |
2009 |
Genes Chromosomes Cancer |
pmid:18836996
|
Smetana K et al. |
To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A. |
2008 Jul-Sep |
Eur J Histochem |
pmid:18840553
|
Hitchler MJ et al. |
Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells. |
2008 |
Free Radic. Biol. Med. |
pmid:18845242
|
Lee SH et al. |
Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells. |
2009 |
Oncogene |
pmid:18850007
|
Wu X et al. |
Trichostatin A improved epigenetic modifications of transfected cells but did not improve subsequent cloned embryo development. |
2008 |
Anim. Biotechnol. |
pmid:18855246
|