Mukhopadhyay NK et al. |
Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer. |
2006 |
Ann. Thorac. Surg. |
pmid:16488717
|
Swanson S |
Invited commentary. |
2006 |
Ann. Thorac. Surg. |
pmid:16488718
|
Song YF et al. |
High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma. |
2006 |
J. Clin. Pathol. |
pmid:16489177
|
Rokhlin OW et al. |
Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells. |
2006 |
Mol. Cancer Res. |
pmid:16513842
|
Endo T et al. |
Activities of maturation-promoting factor (MPF) and mitogen-activated protein kinase (MAPK) are not required for the global histone deacetylation observed after germinal vesicle breakdown (GVBD) in porcine oocytes. |
2006 |
Reproduction |
pmid:16514187
|
Hansen KR et al. |
Evolutionary-conserved telomere-linked helicase genes of fission yeast are repressed by silencing factors, RNAi components and the telomere-binding protein Taz1. |
2006 |
Nucleic Acids Res. |
pmid:16407326
|
Fischer S et al. |
Histone acetylation dependent allelic expression imbalance of BAPX1 in patients with the oculo-auriculo-vertebral spectrum. |
2006 |
Hum. Mol. Genet. |
pmid:16407370
|
Bieler A et al. |
Novel three-pronged strategy to enhance cancer cell killing in glioblastoma cell lines: histone deacetylase inhibitor, chemotherapy, and oncolytic adenovirus dl520. |
2006 |
Hum. Gene Ther. |
pmid:16409125
|
Lo PK et al. |
Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer. |
2006 |
Cancer Biol. Ther. |
pmid:16410723
|
Williams SA et al. |
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. |
2006 |
EMBO J. |
pmid:16319923
|
ChuÄkin IA et al. |
[Anti-proliferative effect of histone deacetylase inhibitors on murine embryonic stem cells]. |
2006 |
Tsitologiia |
pmid:17147260
|
Zou B et al. |
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. |
2006 |
Gastroenterology |
pmid:17087954
|
Anderson I |
Deacetylase inhibitors aid recovery in muscular dystrophy. |
2006 |
Lancet Neurol |
pmid:17089447
|
Kiefer J et al. |
Mixtures of SCFA, composed according to physiologically available concentrations in the gut lumen, modulate histone acetylation in human HT29 colon cancer cells. |
2006 |
Br. J. Nutr. |
pmid:17092367
|
Kishigami S et al. |
Epigenetic abnormalities of the mouse paternal zygotic genome associated with microinsemination of round spermatids. |
2006 |
Dev. Biol. |
pmid:16325170
|
Mogal A and Abdulkadir SA |
Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes. |
2006 |
Mol. Cell. Probes |
pmid:16326072
|
Gan Y et al. |
Dual effects of histone deacetylase inhibition by trichostatin A on endothelial nitric oxide synthase expression in endothelial cells. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16338217
|
Nishiyama A et al. |
Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatin. |
2006 |
Mol. Biol. Cell |
pmid:16339075
|
Trapp J et al. |
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. |
2006 |
J. Med. Chem. |
pmid:17149860
|
Baradari V et al. |
Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells. |
2006 |
Endocr. Relat. Cancer |
pmid:17158768
|
Taghiyev AF et al. |
TSA-induced cell death in prostate cancer cell lines is caspase-2 dependent and involves the PIDDosome. |
2006 |
Cancer Biol. Ther. |
pmid:17110788
|
Tada Y et al. |
Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer. |
2006 |
J. Natl. Cancer Inst. |
pmid:16537832
|
Bishop CL et al. |
Role for centromeric heterochromatin and PML nuclear bodies in the cellular response to foreign DNA. |
2006 |
Mol. Cell. Biol. |
pmid:16537904
|
Gagnon JF et al. |
Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer. |
2006 |
Clin. Cancer Res. |
pmid:16551870
|
Rebbaa A et al. |
The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis. |
2006 |
Cell Death Differ. |
pmid:16557274
|
Suuronen T et al. |
Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia. |
2006 |
Neurochem. Int. |
pmid:16797784
|
Krishnan M et al. |
Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. |
2006 |
FASEB J. |
pmid:16246867
|
Wallace DM et al. |
Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:16799012
|
Pampalakis G and Sotiropoulou G |
Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. |
2006 |
Biol. Chem. |
pmid:16800739
|
Wang Y et al. |
Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. |
2006 |
Arthritis Rheum. |
pmid:16802366
|
Morinobu A et al. |
Trichostatin A cooperates with Fas-mediated signal to induce apoptosis in rheumatoid arthritis synovial fibroblasts. |
2006 |
J. Rheumatol. |
pmid:16755652
|
Son YO et al. |
Involvement of caspase activation and mitochondrial stress in trichostatin A-induced apoptosis of Burkitt's lymphoma cell line, Akata. |
2006 |
J. Cell. Biochem. |
pmid:16817225
|
Lau QC et al. |
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. |
2006 |
Cancer Res. |
pmid:16818622
|
Yamada N et al. |
MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer. |
2006 |
Int. J. Cancer |
pmid:16721789
|
Kim Y et al. |
Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation. |
2006 |
J. Steroid Biochem. Mol. Biol. |
pmid:16723222
|
Santander VS et al. |
Tubulin must be acetylated in order to form a complex with membrane Na(+),K (+)-ATPase and to inhibit its enzyme activity. |
2006 |
Mol. Cell. Biochem. |
pmid:16733802
|
Kong Y et al. |
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. |
2006 |
Circulation |
pmid:16735673
|
Dannenberg LO et al. |
Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. |
2006 |
Alcohol. Clin. Exp. Res. |
pmid:16737450
|
Cabrero JR et al. |
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. |
2006 |
Mol. Biol. Cell |
pmid:16738306
|
Vulcano F et al. |
HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers. |
2006 |
Exp. Cell Res. |
pmid:16739251
|
Qi H and Ratnam M |
Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. |
2006 |
Cancer Res. |
pmid:16740727
|
Nusinzon I and Horvath CM |
Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation. |
2006 |
Mol. Cell. Biol. |
pmid:16581785
|
Ibanez de Caceres I et al. |
Identification of novel target genes by an epigenetic reactivation screen of renal cancer. |
2006 |
Cancer Res. |
pmid:16707423
|
Imre G et al. |
Histone deacetylase inhibitors suppress the inducibility of nuclear factor-kappaB by tumor necrosis factor-alpha receptor-1 down-regulation. |
2006 |
Cancer Res. |
pmid:16707469
|
Jaalouk DE et al. |
Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors. |
2006 |
Virol. J. |
pmid:16603064
|
Kim MY et al. |
Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. |
2006 |
Mol. Endocrinol. |
pmid:16497729
|
Leng Y and Chuang DM |
Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. |
2006 |
J. Neurosci. |
pmid:16837598
|
Scott SA et al. |
5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation. |
2006 |
Leuk. Res. |
pmid:16043219
|
Hofmann A et al. |
Epigenetic regulation of lentiviral transgene vectors in a large animal model. |
2006 |
Mol. Ther. |
pmid:16140581
|
Aung HT et al. |
LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression. |
2006 |
FASEB J. |
pmid:16816106
|
Clem BF and Clark BJ |
Association of the mSin3A-histone deacetylase 1/2 corepressor complex with the mouse steroidogenic acute regulatory protein gene. |
2006 |
Mol. Endocrinol. |
pmid:16109738
|
Mai A et al. |
Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. |
2006 |
J. Med. Chem. |
pmid:17004718
|
Yao J et al. |
NF-kappaB signaling pathway is involved in growth inhibition, G2/M arrest and apoptosis induced by Trichostatin A in human tongue carcinoma cells. |
2006 |
Pharmacol. Res. |
pmid:17005413
|
Inoue K et al. |
Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. |
2006 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17008592
|
Baqir S and Smith LC |
Inhibitors of histone deacetylases and DNA methyltransferases alter imprinted gene regulation in embryonic stem cells. |
2006 |
Cloning Stem Cells |
pmid:17009896
|
Hong ZY et al. |
[Mechanism of apoptosis induced by trichostatin A in leukemia Molt-4 cells analyzed by microarray]. |
2006 |
Ai Zheng |
pmid:16965673
|
Banwell CM et al. |
Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. |
2006 |
Clin. Cancer Res. |
pmid:16609009
|
Jung JW et al. |
Effects of the histone deacetylases inhibitors sodium butyrate and trichostatin A on the inhibition of gap junctional intercellular communication by H2O2- and 12-O-tetradecanoylphorbol-13-acetate in rat liver epithelial cells. |
2006 |
Cancer Lett. |
pmid:16337085
|
Tyson-Capper AJ et al. |
Characterization of cellular retinoid-binding proteins in human myometrium during pregnancy. |
2006 |
Mol. Hum. Reprod. |
pmid:16959971
|
Chen J et al. |
Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells. |
2006 |
Pharmazie |
pmid:16964716
|
Kim MY et al. |
A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16924111
|
Mühlethaler-Mottet A et al. |
Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. |
2006 |
BMC Cancer |
pmid:16930472
|
Suzuki T et al. |
Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. |
2006 |
J. Med. Chem. |
pmid:16884291
|
Kim TY et al. |
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. |
2006 |
Cancer Res. |
pmid:16885346
|
Kimura N et al. |
Alteration of developmental program in Paramecium by treatment with trichostatin a: a possible involvement of histone modification. |
2006 |
Protist |
pmid:16839811
|
Monte M et al. |
MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16847267
|
Zaveri NT et al. |
Regulation of the prepronociceptin gene and its effect on neuronal differentiation. |
2006 |
Gene |
pmid:16935438
|
Dokras A et al. |
Epigenetic regulation of maspin expression in the human placenta. |
2006 |
Mol. Hum. Reprod. |
pmid:16936308
|
Yamamura K et al. |
Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis. |
2006 |
Br. J. Haematol. |
pmid:16939493
|
Deng G et al. |
Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. |
2006 |
Int. J. Cancer |
pmid:16425274
|
Huang L et al. |
Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression. |
2006 |
Neurosci. Lett. |
pmid:16426753
|
Kim IA et al. |
Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53. |
2006 |
Clin. Cancer Res. |
pmid:16467109
|
Osborn NK et al. |
Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia. |
2006 |
Clin. Gastroenterol. Hepatol. |
pmid:16469682
|
Baraz L et al. |
Tumor suppressor p53 regulates heparanase gene expression. |
2006 |
Oncogene |
pmid:16474844
|
Gialitakis M et al. |
Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. |
2006 |
Nucleic Acids Res. |
pmid:16452299
|
Kwon HS et al. |
Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression. |
2006 Mar-Apr |
Biochim. Biophys. Acta |
pmid:16757381
|
Hosseinkhani M et al. |
Trichostatin A induces myocardial differentiation of monkey ES cells. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17368572
|
Kim HJ et al. |
Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17371805
|
Kitamura H et al. |
Down-regulation of HLA class I antigens in prostate cancer tissues and up-regulation by histone deacetylase inhibition. |
2007 |
J. Urol. |
pmid:17574613
|
Hellebrekers DM et al. |
Identification of epigenetically silenced genes in tumor endothelial cells. |
2007 |
Cancer Res. |
pmid:17483324
|
Yi T et al. |
Trichostatin A-mediated upregulation of p21(WAF1) contributes to osteoclast apoptosis. |
2007 |
Exp. Mol. Med. |
pmid:17464183
|
Wong CM et al. |
Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma. |
2007 |
Hepatology |
pmid:17464989
|
Chen Y et al. |
Homeobox gene HOP has a potential tumor suppressive activity in human lung cancer. |
2007 |
Int. J. Cancer |
pmid:17417779
|
Berg T et al. |
Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines. |
2007 |
Leuk. Res. |
pmid:17056112
|
Sato N et al. |
RhoB is frequently downregulated in non-small-cell lung cancer and resides in the 2p24 homozygous deletion region of a lung cancer cell line. |
2007 |
Int. J. Cancer |
pmid:17096327
|
Wu Y et al. |
The zinc finger repressor, ZBP-89, recruits histone deacetylase 1 to repress vimentin gene expression. |
2007 |
Genes Cells |
pmid:17663720
|
Schneider G et al. |
HDAC3 is linked to cell cycle machinery in MiaPaCa2 cells by regulating transcription of skp2. |
2007 |
Cell Prolif. |
pmid:17635519
|
Bode KA et al. |
Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. |
2007 |
Immunology |
pmid:17635610
|
Zhang L et al. |
Small molecule regulators of autophagy identified by an image-based high-throughput screen. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18024584
|
Park JJ et al. |
Functional interaction of the human cytomegalovirus IE2 protein with histone deacetylase 2 in infected human fibroblasts. |
2007 |
J. Gen. Virol. |
pmid:18024889
|
Moiseeva EP et al. |
Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells. |
2007 |
Mol. Cancer Ther. |
pmid:18025290
|
Mazzarelli P et al. |
Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation? |
2007 |
Cancer Biol. Ther. |
pmid:18253084
|
Feng W et al. |
Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer. |
2007 |
Int. J. Cancer |
pmid:17230502
|
Karam JA et al. |
The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy. |
2007 |
Int. J. Cancer |
pmid:17230511
|
Ghosh AK et al. |
Trichostatin A blocks TGF-beta-induced collagen gene expression in skin fibroblasts: involvement of Sp1. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17234156
|
Wang F et al. |
Dynamic reprogramming of histone acetylation and methylation in the first cell cycle of cloned mouse embryos. |
2007 |
Biol. Reprod. |
pmid:17823087
|
De los Santos M et al. |
Combined effects of retinoic acid and histone deacetylase inhibitors on human neuroblastoma SH-SY5Y cells. |
2007 |
Mol. Cancer Ther. |
pmid:17431121
|
Qi J et al. |
[Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor]. |
2007 |
Zhonghua Zhong Liu Za Zhi |
pmid:18396643
|
Qi J et al. |
[The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor]. |
2007 |
Zhonghua Yi Xue Za Zhi |
pmid:17923031
|
Pulukuri SM et al. |
Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator. |
2007 |
J. Biol. Chem. |
pmid:17923479
|