Foubister V |
Anticancer drug shows promise against lupus. |
2003 |
Drug Discov. Today |
pmid:12681930
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Park WH et al. |
Trichostatin inhibits the growth of ACHN renal cell carcinoma cells via cell cycle arrest in association with p27, or apoptosis. |
2003 |
Int. J. Oncol. |
pmid:12684681
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Schauber J et al. |
Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. |
2003 |
Gut |
pmid:12692061
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Rambhatla L et al. |
Generation of hepatocyte-like cells from human embryonic stem cells. |
2003 |
Cell Transplant |
pmid:12693659
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Lee SC et al. |
Activation of terminal B cell differentiation by inhibition of histone deacetylation. |
2003 |
Mol. Immunol. |
pmid:12695118
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Zika E et al. |
Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation. |
2003 |
Mol. Cell. Biol. |
pmid:12697811
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Mihaylova VT et al. |
Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. |
2003 |
Mol. Cell. Biol. |
pmid:12697826
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Valenta T et al. |
HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells. |
2003 |
Nucleic Acids Res. |
pmid:12711682
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Arora T et al. |
PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4. |
2003 |
J. Biol. Chem. |
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Yasui W et al. |
Histone acetylation and gastrointestinal carcinogenesis. |
2003 |
Ann. N. Y. Acad. Sci. |
pmid:12724227
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Jedrusik MA and Schulze E |
Telomeric position effect variegation in Saccharomyces cerevisiae by Caenorhabditis elegans linker histones suggests a mechanistic connection between germ line and telomeric silencing. |
2003 |
Mol. Cell. Biol. |
pmid:12724425
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Farhan H et al. |
Genistein inhibits vitamin D hydroxylases CYP24 and CYP27B1 expression in prostate cells. |
2003 |
J. Steroid Biochem. Mol. Biol. |
pmid:12732287
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Chambers AE et al. |
Histone acetylation-mediated regulation of genes in leukaemic cells. |
2003 |
Eur. J. Cancer |
pmid:12736119
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Hoever G et al. |
The mechanism of 3'-azido-2',3'-dideoxythymidine resistance to human lymphoid cells. |
2003 |
Int. J. Mol. Med. |
pmid:12736716
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Swank RA et al. |
The histone deacetylase inhibitor, trichostatin A, reactivates the developmentally silenced gamma globin expression in somatic cell hybrids and induces gamma gene expression in adult BFUe cultures. |
2003 May-Jun |
Blood Cells Mol. Dis. |
pmid:12737942
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Craig JM et al. |
Centromeric chromatin pliability and memory at a human neocentromere. |
2003 |
EMBO J. |
pmid:12743043
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Enright BP et al. |
Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2'-deoxycytidine. |
2003 |
Biol. Reprod. |
pmid:12748129
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Van Ommeslaeghe K et al. |
Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12749885
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Zhao S et al. |
Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor beta Type II receptor expression in human pancreatic cancer cells. |
2003 |
Cancer Res. |
pmid:12750289
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Klisovic DD et al. |
Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines. |
2003 |
Invest. Ophthalmol. Vis. Sci. |
pmid:12766035
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Génin P et al. |
Impairment of interferon-induced IRF-7 gene expression due to inhibition of ISGF3 formation by trichostatin A. |
2003 |
J. Virol. |
pmid:12768031
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Bartoli A et al. |
Effect of trichostatin a and 5'-azacytidine on transgene reactivation in U937 transduced cells. |
2003 |
Pharmacol. Res. |
pmid:12770523
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Koeller KM et al. |
Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation. |
2003 |
Chem. Biol. |
pmid:12770822
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Agoulnik IU et al. |
Repressors of androgen and progesterone receptor action. |
2003 |
J. Biol. Chem. |
pmid:12771131
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Kang J et al. |
Nickel-induced histone hypoacetylation: the role of reactive oxygen species. |
2003 |
Toxicol. Sci. |
pmid:12773760
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Maatouk DM and Resnick JL |
Continuing primordial germ cell differentiation in the mouse embryo is a cell-intrinsic program sensitive to DNA methylation. |
2003 |
Dev. Biol. |
pmid:12781693
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Ju R and Muller MT |
Histone deacetylase inhibitors activate p21(WAF1) expression via ATM. |
2003 |
Cancer Res. |
pmid:12782595
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Chua YL et al. |
The transcriptional enhancer of the pea plastocyanin gene associates with the nuclear matrix and regulates gene expression through histone acetylation. |
2003 |
Plant Cell |
pmid:12782737
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Cecconi D et al. |
Proteomic profiling of pancreatic ductal carcinoma cell lines treated with trichostatin-A. |
2003 |
Electrophoresis |
pmid:12783462
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Park KK et al. |
Modulation of Sp1-dependent transcription by a cis-acting E2F element in dhfr promoter. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12788094
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Marks J et al. |
Two functionally divergent p53-responsive elements in the rat bradykinin B2 receptor promoter. |
2003 |
J. Biol. Chem. |
pmid:12791684
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Valls E et al. |
The SV40 T antigen modulates CBP histone acetyltransferase activity. |
2003 |
Nucleic Acids Res. |
pmid:12799439
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Ferguson M et al. |
Histone deacetylase inhibition is associated with transcriptional repression of the Hmga2 gene. |
2003 |
Nucleic Acids Res. |
pmid:12799440
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Ji Y et al. |
A multistep mechanism for the activation of rearrangement in the immune system. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12802019
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Nemajerová A et al. |
Trichostatin A suppresses transformation by the v-myb oncogene in BM2 cells. |
2003 |
J. Hematother. Stem Cell Res. |
pmid:12804181
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Park PH et al. |
Acetylation of histone H3 at lysine 9 by ethanol in rat hepatocytes. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12804592
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Méndez-Pertuz M et al. |
The thyroid hormone receptor antagonizes CREB-mediated transcription. |
2003 |
EMBO J. |
pmid:12805224
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Illi B et al. |
Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression. |
2003 |
Circ. Res. |
pmid:12805238
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Bhakat KK and Mitra S |
CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration. |
2003 |
Carcinogenesis |
pmid:12807730
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Lopatina NG et al. |
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12810068
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Liu LT et al. |
Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. |
2003 |
Cancer Res. |
pmid:12810630
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Shin HJ et al. |
Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation. |
2003 |
Oncogene |
pmid:12813458
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Kim TY et al. |
Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells. |
2003 |
Oncogene |
pmid:12813468
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Kim H et al. |
The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12816733
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Klan N et al. |
Trichostatin A and structurally related histone deacetylase inhibitors induce 5-lipoxygenase promoter activity. |
2003 |
Biol. Chem. |
pmid:12817474
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Yamada Y et al. |
Aberrant methylation of the vascular endothelial growth factor receptor-1 gene in prostate cancer. |
2003 |
Cancer Sci. |
pmid:12824880
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Kim JM et al. |
Changes in histone acetylation during mouse oocyte meiosis. |
2003 |
J. Cell Biol. |
pmid:12835313
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Ammanamanchi S et al. |
Acetylated sp3 is a transcriptional activator. |
2003 |
J. Biol. Chem. |
pmid:12837748
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James SY et al. |
Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells. |
2003 |
Cancer Res. |
pmid:12839938
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Krämer OH et al. |
The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2. |
2003 |
EMBO J. |
pmid:12840003
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Cho B et al. |
Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12849980
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Pivot-Pajot C et al. |
Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. |
2003 |
Mol. Cell. Biol. |
pmid:12861021
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Grassi G et al. |
Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87. |
2003 |
Carcinogenesis |
pmid:12869421
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Marshall S et al. |
Enhanced expression of uridine diphosphate-N-acetylglucosaminyl transferase (OGT) in a stable, tetracycline-inducible HeLa cell line using histone deacetylase inhibitors: kinetics of cytosolic OGT accumulation and nuclear translocation. |
2003 |
Anal. Biochem. |
pmid:12871726
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Koch A et al. |
Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages. |
2004 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12871851
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McGhee L et al. |
Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism. |
2003 |
J. Cell. Biochem. |
pmid:12874834
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Chun AC and Jin DY |
Transcriptional regulation of mitotic checkpoint gene MAD1 by p53. |
2003 |
J. Biol. Chem. |
pmid:12876282
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Grisolano JL et al. |
An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12881486
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Konduri SD et al. |
Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells. |
2003 |
Oncogene |
pmid:12881707
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Condon JC et al. |
A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12886011
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Ryu JR and Arnosti DN |
Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities. |
2003 |
Nucleic Acids Res. |
pmid:12888527
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Mulholland NM et al. |
Inhibition of MMTV transcription by HDAC inhibitors occurs independent of changes in chromatin remodeling and increased histone acetylation. |
2003 |
Oncogene |
pmid:12894222
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Banwell CM et al. |
Antiproliferative signalling by 1,25(OH)2D3 in prostate and breast cancer is suppressed by a mechanism involving histone deacetylation. |
2003 |
Recent Results Cancer Res. |
pmid:12899515
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Yan Y et al. |
Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure. |
2003 |
Toxicol. Appl. Pharmacol. |
pmid:12902198
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Augenlicht L et al. |
Repression of MUC2 gene expression by butyrate, a physiological regulator of intestinal cell maturation. |
2003 |
Oncogene |
pmid:12902981
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Kishikawa S et al. |
Roles of histone acetylation in the Dnmt1 gene expression. |
2002 |
Nucleic Acids Res. Suppl. |
pmid:12903179
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Massillon D et al. |
Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. |
2003 |
J. Biol. Chem. |
pmid:12915406
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Hong CY et al. |
Expression of MIS in the testis is downregulated by tumor necrosis factor alpha through the negative regulation of SF-1 transactivation by NF-kappa B. |
2003 |
Mol. Cell. Biol. |
pmid:12917325
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Le Masson I et al. |
Yaf9, a novel NuA4 histone acetyltransferase subunit, is required for the cellular response to spindle stress in yeast. |
2003 |
Mol. Cell. Biol. |
pmid:12917332
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Adam E et al. |
Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha. |
2003 |
Mol. Cell. Biol. |
pmid:12917341
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Zhong S et al. |
Phosphorylation at serine 28 and acetylation at lysine 9 of histone H3 induced by trichostatin A. |
2003 |
Oncogene |
pmid:12917630
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Cao H et al. |
Induction of human gamma globin gene expression by histone deacetylase inhibitors. |
2004 |
Blood |
pmid:12920038
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Nakajima M et al. |
Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells. |
2003 |
Toxicol. Lett. |
pmid:12927368
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Papeleu P et al. |
Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes. |
2003 |
J. Hepatol. |
pmid:12927923
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Senawong T et al. |
Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression. |
2003 |
J. Biol. Chem. |
pmid:12930829
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Fass DM et al. |
Deacetylase activity is required for cAMP activation of a subset of CREB target genes. |
2003 |
J. Biol. Chem. |
pmid:12939274
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Zhao C et al. |
A composite motif of the Drosophila morphogenetic protein bicoid critical to transcription control. |
2003 |
J. Biol. Chem. |
pmid:12939280
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Hinoi T et al. |
Silencing of CDX2 expression in colon cancer via a dominant repression pathway. |
2003 |
J. Biol. Chem. |
pmid:12947088
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Nakano M et al. |
Epigenetic assembly of centromeric chromatin at ectopic alpha-satellite sites on human chromosomes. |
2003 |
J. Cell. Sci. |
pmid:12953060
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Kim EJ et al. |
Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML. |
2003 |
Nucleic Acids Res. |
pmid:12954772
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Brugarolas JB et al. |
TSC2 regulates VEGF through mTOR-dependent and -independent pathways. |
2003 |
Cancer Cell |
pmid:12957289
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Fukuoka M et al. |
Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation. |
2003 |
Int. J. Mol. Med. |
pmid:12964026
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Vanommeslaeghe K et al. |
Ab initio study of the binding of Trichostatin A (TSA) in the active site of histone deacetylase like protein (HDLP). |
2003 |
Org. Biomol. Chem. |
pmid:12968347
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Huang H et al. |
[HDAC1 expression and effect of TSA on proliferation and apoptosis of A549 cells]. |
2003 |
Ai Zheng |
pmid:12969522
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Ohike N et al. |
Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas. |
2003 |
Cancer Lett. |
pmid:12969792
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Cimini D et al. |
Histone hyperacetylation in mitosis prevents sister chromatid separation and produces chromosome segregation defects. |
2003 |
Mol. Biol. Cell |
pmid:12972566
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Schuettengruber B et al. |
Autoregulation of mouse histone deacetylase 1 expression. |
2003 |
Mol. Cell. Biol. |
pmid:12972616
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Yang Y et al. |
The histone code regulating expression of the imprinted mouse Igf2r gene. |
2003 |
Endocrinology |
pmid:12975326
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Hu E et al. |
Identification of novel isoform-selective inhibitors within class I histone deacetylases. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12975486
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Xu Y et al. |
SHP-1 sensitizes MCF-7 cells to trichostatin A-induced apoptosis by modulating PI3K-dependent events. |
2003 |
Cell Death Differ. |
pmid:14502244
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Donadelli M et al. |
Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cells. |
2003 |
Mol. Carcinog. |
pmid:14502645
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Tominaga K et al. |
MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner. |
2003 |
J. Biol. Chem. |
pmid:14506250
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Kawai H et al. |
Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor alpha. |
2003 |
Int. J. Cancer |
pmid:14506733
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Kishikawa S et al. |
Control elements of Dnmt1 gene are regulated in cell-cycle dependent manner. |
2003 |
Nucleic Acids Res. Suppl. |
pmid:14510503
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Wegener D et al. |
Improved fluorogenic histone deacetylase assay for high-throughput-screening applications. |
2003 |
Anal. Biochem. |
pmid:14511685
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Remiszewski SW et al. |
N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824). |
2003 |
J. Med. Chem. |
pmid:14521422
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Noh EJ and Lee JS |
Functional interplay between modulation of histone deacetylase activity and its regulatory role in G2-M transition. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14521905
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Li C et al. |
Effect and comparison of sodium butyrate and trichostatin A on the proliferation/differentiation of K562. |
2003 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:14526425
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Margueron R et al. |
Oestrogen receptor alpha increases p21(WAF1/CIP1) gene expression and the antiproliferative activity of histone deacetylase inhibitors in human breast cancer cells. |
2003 |
J. Endocrinol. |
pmid:14529564
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Kagoshima M et al. |
How signaling pathways interact with gene transcription. |
2003 Jan-Mar |
Monaldi Arch Chest Dis |
pmid:14533280
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