Pampalakis G and Sotiropoulou G |
Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. |
2006 |
Biol. Chem. |
pmid:16800739
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Wang Y et al. |
Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. |
2006 |
Arthritis Rheum. |
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Zampetaki A et al. |
TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications. |
2006 |
Biochem. Biophys. Res. Commun. |
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LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression. |
2006 |
FASEB J. |
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Involvement of caspase activation and mitochondrial stress in trichostatin A-induced apoptosis of Burkitt's lymphoma cell line, Akata. |
2006 |
J. Cell. Biochem. |
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RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. |
2006 |
Cancer Res. |
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Foltz G et al. |
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. |
2006 |
Cancer Res. |
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Mori T et al. |
Estrogen receptor-alpha methylation predicts melanoma progression. |
2006 |
Cancer Res. |
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Sato K et al. |
Deficient expression of the DPD gene is caused by epigenetic modification in biliary tract cancer cells, and induces high sensitivity to 5-FU treatment. |
2006 |
Int. J. Oncol. |
pmid:16820886
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Leng Y and Chuang DM |
Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. |
2006 |
J. Neurosci. |
pmid:16837598
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Kimura N et al. |
Alteration of developmental program in Paramecium by treatment with trichostatin a: a possible involvement of histone modification. |
2006 |
Protist |
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Monte M et al. |
MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
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Das PM et al. |
Methylation mediated silencing of TMS1/ASC gene in prostate cancer. |
2006 |
Mol. Cancer |
pmid:16848908
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Puppin C et al. |
HEX expression and localization in normal mammary gland and breast carcinoma. |
2006 |
BMC Cancer |
pmid:16854221
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Dannenberg LO and Edenberg HJ |
Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation. |
2006 |
BMC Genomics |
pmid:16854234
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Bell CW et al. |
The extracellular release of HMGB1 during apoptotic cell death. |
2006 |
Am. J. Physiol., Cell Physiol. |
pmid:16855214
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Olaharski AJ et al. |
The histone deacetylase inhibitor trichostatin a has genotoxic effects in human lymphoblasts in vitro. |
2006 |
Toxicol. Sci. |
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Androgen receptor regulates nuclear trafficking and nuclear domain residency of corepressor HDAC7 in a ligand-dependent fashion. |
2006 |
Exp. Cell Res. |
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Wagner S et al. |
SET-mediated promoter hypoacetylation is a prerequisite for coactivation of the estrogen-responsive pS2 gene by PRMT1. |
2006 |
J. Biol. Chem. |
pmid:16861234
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Zhang X et al. |
Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines. |
2006 |
Oncol. Rep. |
pmid:16865256
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Histone deacetylase 3 represses HTLV-1 tax transcription. |
2006 |
Oncol. Rep. |
pmid:16865259
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van den Boom J et al. |
Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcription-polymerase chain reaction. |
2006 |
Int. J. Cancer |
pmid:16865689
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Gaymes TJ et al. |
Histone deacetylase inhibitors (HDI) cause DNA damage in leukemia cells: a mechanism for leukemia-specific HDI-dependent apoptosis? |
2006 |
Mol. Cancer Res. |
pmid:16877702
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Suzuki T et al. |
Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. |
2006 |
J. Med. Chem. |
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Kim TY et al. |
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. |
2006 |
Cancer Res. |
pmid:16885346
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Liu L and Clipstone NA |
Prostaglandin F2alpha inhibits adipocyte differentiation via a G alpha q-calcium-calcineurin-dependent signaling pathway. |
2007 |
J. Cell. Biochem. |
pmid:16888802
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Hishikawa K and Fujita T |
[Basic research for renal regeneration]. |
2006 |
Nippon Rinsho |
pmid:16895225
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Meisel A et al. |
Inhibition of histone deacetylation protects wild-type but not gelsolin-deficient neurons from oxygen/glucose deprivation. |
2006 |
J. Neurochem. |
pmid:16895577
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Bai J et al. |
Histone deacetylase inhibitor trichostatin A and proteasome inhibitor PS-341 synergistically induce apoptosis in pancreatic cancer cells. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16904634
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Synthesis of rigid trichostatin A analogs as HDAC inhibitors. |
2006 |
Bioorg. Med. Chem. Lett. |
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Okamoto H et al. |
Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1). |
2006 |
J. Atheroscler. Thromb. |
pmid:16908950
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B29 gene silencing in pituitary cells is regulated by its 3' enhancer. |
2006 |
J. Mol. Biol. |
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Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. |
2006 |
Nat. Chem. Biol. |
pmid:16921367
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Wang LG et al. |
Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer. |
2007 |
Mol. Carcinog. |
pmid:16921492
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Kim MY et al. |
A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16924111
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Mühlethaler-Mottet A et al. |
Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. |
2006 |
BMC Cancer |
pmid:16930472
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Ondrousková E et al. |
A proteomic analysis of protein variations during differentiation of v-myb-transformed monoblasts. |
2007 |
Leuk. Res. |
pmid:16930693
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Zaveri NT et al. |
Regulation of the prepronociceptin gene and its effect on neuronal differentiation. |
2006 |
Gene |
pmid:16935438
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Dokras A et al. |
Epigenetic regulation of maspin expression in the human placenta. |
2006 |
Mol. Hum. Reprod. |
pmid:16936308
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Yamamura K et al. |
Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis. |
2006 |
Br. J. Haematol. |
pmid:16939493
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Zhang Y et al. |
Phosphatidylinositol 3-kinase/protein kinase Czeta-induced phosphorylation of Sp1 and p107 repressor release have a critical role in histone deacetylase inhibitor-mediated derepression [corrected] of transcription of the luteinizing hormone receptor gene. |
2006 |
Mol. Cell. Biol. |
pmid:16943418
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Dynamic regulation of histone modifications in Xenopus oocytes through histone exchange. |
2006 |
Mol. Cell. Biol. |
pmid:16943430
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Topark-Ngarm A et al. |
CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene. |
2006 |
J. Biol. Chem. |
pmid:16950772
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Kogai T et al. |
Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. |
2006 |
Endocr. Relat. Cancer |
pmid:16954431
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Tyson-Capper AJ et al. |
Characterization of cellular retinoid-binding proteins in human myometrium during pregnancy. |
2006 |
Mol. Hum. Reprod. |
pmid:16959971
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Chen J et al. |
Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells. |
2006 |
Pharmazie |
pmid:16964716
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Hong ZY et al. |
[Mechanism of apoptosis induced by trichostatin A in leukemia Molt-4 cells analyzed by microarray]. |
2006 |
Ai Zheng |
pmid:16965673
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Wang Q et al. |
Histone phosphorylation and pericentromeric histone modifications in oocyte meiosis. |
2006 |
Cell Cycle |
pmid:16969090
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Yang H et al. |
Dexamethasone-induced protein degradation in cultured myotubes is p300/HAT dependent. |
2007 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:16973938
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A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. |
2006 |
Genes Dev. |
pmid:16980585
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Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors. |
2006 |
Nat. Med. |
pmid:16980968
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[Therapeutic strategies for patients with relapsed acute promyelocytic leukemia]. |
2006 |
Rinsho Ketsueki |
pmid:16986710
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Liu T et al. |
Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells. |
2007 |
Carcinogenesis |
pmid:16990345
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Claus R et al. |
Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression. |
2006 |
J. Leukoc. Biol. |
pmid:17000900
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Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. |
2006 |
J. Med. Chem. |
pmid:17004718
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Yao J et al. |
NF-kappaB signaling pathway is involved in growth inhibition, G2/M arrest and apoptosis induced by Trichostatin A in human tongue carcinoma cells. |
2006 |
Pharmacol. Res. |
pmid:17005413
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Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. |
2006 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17008592
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Baqir S and Smith LC |
Inhibitors of histone deacetylases and DNA methyltransferases alter imprinted gene regulation in embryonic stem cells. |
2006 |
Cloning Stem Cells |
pmid:17009896
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Sah NK et al. |
Effect of downregulation of survivin expression on radiosensitivity of human epidermoid carcinoma cells. |
2006 |
Int. J. Radiat. Oncol. Biol. Phys. |
pmid:17011457
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Kumar KS et al. |
Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells. |
2006 |
Oncol. Rep. |
pmid:17016591
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Alao JP et al. |
Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells. |
2006 |
Mol. Cancer |
pmid:17018141
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An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis. |
2006 |
Cancer Res. |
pmid:17018599
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Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity. |
2007 |
Int. J. Cancer |
pmid:17019711
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Ooi L et al. |
BRG1 chromatin remodeling activity is required for efficient chromatin binding by repressor element 1-silencing transcription factor (REST) and facilitates REST-mediated repression. |
2006 |
J. Biol. Chem. |
pmid:17023429
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Epigenetic allele silencing unveils recessive RYR1 mutations in core myopathies. |
2006 |
Am. J. Hum. Genet. |
pmid:17033962
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Zhong S et al. |
Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer. |
2007 |
Oncogene |
pmid:17043644
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Berg T et al. |
Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines. |
2007 |
Leuk. Res. |
pmid:17056112
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Uchida H et al. |
Histone deacetylase inhibitors stimulate cell migration in human endometrial adenocarcinoma cells through up-regulation of glycodelin. |
2007 |
Endocrinology |
pmid:17068141
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Kishigami S et al. |
Successful mouse cloning of an outbred strain by trichostatin A treatment after somatic nuclear transfer. |
2007 |
J. Reprod. Dev. |
pmid:17077581
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Balasubramaniyan V et al. |
Effects of histone deacetylation inhibition on neuronal differentiation of embryonic mouse neural stem cells. |
2006 |
Neuroscience |
pmid:17084985
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Zou B et al. |
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. |
2006 |
Gastroenterology |
pmid:17087954
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Anderson I |
Deacetylase inhibitors aid recovery in muscular dystrophy. |
2006 |
Lancet Neurol |
pmid:17089447
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Kiefer J et al. |
Mixtures of SCFA, composed according to physiologically available concentrations in the gut lumen, modulate histone acetylation in human HT29 colon cancer cells. |
2006 |
Br. J. Nutr. |
pmid:17092367
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Sato N et al. |
RhoB is frequently downregulated in non-small-cell lung cancer and resides in the 2p24 homozygous deletion region of a lung cancer cell line. |
2007 |
Int. J. Cancer |
pmid:17096327
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Zhang R et al. |
HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells. |
2007 |
Mol. Cell. Biol. |
pmid:17101789
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Taghiyev AF et al. |
TSA-induced cell death in prostate cancer cell lines is caspase-2 dependent and involves the PIDDosome. |
2006 |
Cancer Biol. Ther. |
pmid:17110788
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Sestáková B and Vachtenheim J |
Distinct co-regulation of endogenous versus transfected MITF-dependent tyrosinase promoter. |
2006 |
Folia Biol. (Praha) |
pmid:17116288
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Roy S and Tenniswood M |
Site-specific acetylation of p53 directs selective transcription complex assembly. |
2007 |
J. Biol. Chem. |
pmid:17121856
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Dowdy SC et al. |
Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells. |
2006 |
Mol. Cancer Ther. |
pmid:17121923
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Saunders LR and Verdin E |
Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors. |
2006 |
Mol. Cancer Ther. |
pmid:17121924
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Henkens T et al. |
Trichostatin A, a critical factor in maintaining the functional differentiation of primary cultured rat hepatocytes. |
2007 |
Toxicol. Appl. Pharmacol. |
pmid:17125810
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Yoshikawa M et al. |
Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-beta1 in human renal epithelial cells. |
2007 |
J. Am. Soc. Nephrol. |
pmid:17135397
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Reddy RM et al. |
Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor Trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade. |
2007 |
Apoptosis |
pmid:17136498
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Fang S et al. |
Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. |
2007 |
Mol. Cell. Biol. |
pmid:17145766
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ChuÄkin IA et al. |
[Anti-proliferative effect of histone deacetylase inhibitors on murine embryonic stem cells]. |
2006 |
Tsitologiia |
pmid:17147260
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Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. |
2006 |
J. Med. Chem. |
pmid:17149860
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Long JE and Cai X |
Igf-2r expression regulated by epigenetic modification and the locus of gene imprinting disrupted in cloned cattle. |
2007 |
Gene |
pmid:17150312
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Baradari V et al. |
Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells. |
2006 |
Endocr. Relat. Cancer |
pmid:17158768
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Liu TX et al. |
Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation. |
2007 |
Nat. Med. |
pmid:17159988
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Lee JH et al. |
Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells. |
2006 |
Mol. Cancer Ther. |
pmid:17172411
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Shimazu T et al. |
Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing. |
2007 |
J. Biol. Chem. |
pmid:17172643
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Januchowski R and Jagodzinski PP |
Trichostatin A down-regulates ZAP-70, LAT and SLP-76 content in Jurkat T cells. |
2007 |
Int. Immunopharmacol. |
pmid:17178387
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Araki H et al. |
Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential. |
2007 |
Blood |
pmid:17185465
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Lee EL et al. |
Impaired activity of volume-sensitive Cl- channel is involved in cisplatin resistance of cancer cells. |
2007 |
J. Cell. Physiol. |
pmid:17186499
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Koh E et al. |
Trichostatin A and 5-aza-2'-deoxycytidine switch S1P from an inhibitor to a stimulator of motility through epigenetic regulation of S1P receptors. |
2007 |
Cancer Lett. |
pmid:17189669
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Kovács P and Csaba G |
The effect of histone deacetylase inhibitor trichostatin A (TSA) on the incorporation of 32P (Pi) and 3H-palmitic acid into the phospholipids of Tetrahymena. |
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Cell Biochem. Funct. |
pmid:17191269
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Bazhin AV et al. |
Expression of GAGE family proteins in malignant melanoma. |
2007 |
Cancer Lett. |
pmid:17194529
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Markova NG et al. |
Inhibition of histone deacetylation promotes abnormal epidermal differentiation and specifically suppresses the expression of the late differentiation marker profilaggrin. |
2007 |
J. Invest. Dermatol. |
pmid:17195011
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Fujita Y et al. |
Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. |
2007 |
Dev. Cell |
pmid:17199038
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Katz RA et al. |
High-frequency epigenetic repression and silencing of retroviruses can be antagonized by histone deacetylase inhibitors and transcriptional activators, but uniform reactivation in cell clones is restricted by additional mechanisms. |
2007 |
J. Virol. |
pmid:17202206
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