Sanyal S et al. |
Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. |
2002 |
J. Biol. Chem. |
pmid:11705994
|
Inoue H et al. |
Histone deacetylase inhibitors sensitize human colonic adenocarcinoma cell lines to TNF-related apoptosis inducing ligand-mediated apoptosis. |
2002 |
Int. J. Mol. Med. |
pmid:11956660
|
Galasinski SC et al. |
Global regulation of post-translational modifications on core histones. |
2002 |
J. Biol. Chem. |
pmid:11709551
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A inhibit vascular endothelial growth factor (VEGF) secretion from human glioblastoma cells. |
2002 |
Brain Tumor Pathol |
pmid:12622137
|
Suzuki-Mizushima Y et al. |
Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells. |
2002 |
Brain Res. |
pmid:12270499
|
Boutillier AL et al. |
Constitutive repression of E2F1 transcriptional activity through HDAC proteins is essential for neuronal survival. |
2002 |
Ann. N. Y. Acad. Sci. |
pmid:12485907
|
Zarnegar R et al. |
Increasing the effectiveness of radioactive iodine therapy in the treatment of thyroid cancer using Trichostatin A, a histone deacetylase inhibitor. |
2002 |
Surgery |
pmid:12490845
|
Chen T et al. |
Histone acetylation is involved in hsp70 gene transcription regulation in Drosophila melanogaster. |
2002 |
Arch. Biochem. Biophys. |
pmid:12464268
|
Rombouts K et al. |
Actin filament formation, reorganization and migration are impaired in hepatic stellate cells under influence of trichostatin A, a histone deacetylase inhibitor. |
2002 |
J. Hepatol. |
pmid:12445420
|
Guo WH et al. |
Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor. |
2002 |
Oncogene |
pmid:12447699
|
Marin-Husstege M et al. |
Histone deacetylase activity is necessary for oligodendrocyte lineage progression. |
2002 |
J. Neurosci. |
pmid:12451133
|
Wang ZM et al. |
Trichostatin A inhibits proliferation and induces expression of p21WAF and p27 in human brain tumor cell lines. |
2002 |
Ai Zheng |
pmid:12508652
|
Duharcourt S and Yao MC |
Role of histone deacetylation in developmentally programmed DNA rearrangements in Tetrahymena thermophila. |
2002 |
Eukaryotic Cell |
pmid:12455963
|
Strait KA et al. |
Cell cycle blockade and differentiation of ovarian cancer cells by the histone deacetylase inhibitor trichostatin A are associated with changes in p21, Rb, and Id proteins. |
2002 |
Mol. Cancer Ther. |
pmid:12479699
|
Blagosklonny MV et al. |
Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity. |
2002 |
Mol. Cancer Ther. |
pmid:12481415
|
Drewell RA et al. |
Methylation-dependent silencing at the H19 imprinting control region by MeCP2. |
2002 |
Nucleic Acids Res. |
pmid:11861904
|
Murphy JC et al. |
Control of cytomegalovirus lytic gene expression by histone acetylation. |
2002 |
EMBO J. |
pmid:11867539
|
Kim JY et al. |
Probing lysine acetylation with a modification-specific marker ion using high-performance liquid chromatography/electrospray-mass spectrometry with collision-induced dissociation. |
2002 |
Anal. Chem. |
pmid:12433071
|
Elaut G et al. |
Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes. |
2002 |
Drug Metab. Dispos. |
pmid:12433798
|
Yáñez RJ and Porter AC |
A chromosomal position effect on gene targeting in human cells. |
2002 |
Nucleic Acids Res. |
pmid:12433992
|
Herold C et al. |
The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells. |
2002 |
J. Hepatol. |
pmid:11830335
|
Zhou DC et al. |
Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo. |
2002 |
Blood |
pmid:11830487
|
Valapour M et al. |
Histone deacetylation inhibits IL4 gene expression in T cells. |
2002 |
J. Allergy Clin. Immunol. |
pmid:11842291
|
McBurney MW et al. |
Evidence for repeat-induced gene silencing in cultured Mammalian cells: inactivation of tandem repeats of transfected genes. |
2002 |
Exp. Cell Res. |
pmid:11855851
|
Hou M et al. |
The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells. |
2002 |
Exp. Cell Res. |
pmid:11855854
|
Remiszewski SW et al. |
Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates. |
2002 |
J. Med. Chem. |
pmid:11831887
|
Kiefer SM et al. |
Murine Sall1 represses transcription by recruiting a histone deacetylase complex. |
2002 |
J. Biol. Chem. |
pmid:11836251
|
Roddie PH et al. |
Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1. |
2002 |
Leukemia |
pmid:11840267
|
Taniura S et al. |
Transcriptional regulation of cyclooxygenase-1 by histone deacetylase inhibitors in normal human astrocyte cells. |
2002 |
J. Biol. Chem. |
pmid:11877441
|
Heltweg B and Jung M |
A microplate reader-based nonisotopic histone deacetylase activity assay. |
2002 |
Anal. Biochem. |
pmid:11878795
|
Kamitani H et al. |
Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced. |
2002 |
Neuro-oncology |
pmid:11916500
|
Kishikawa S et al. |
Roles of histone acetylation in the Dnmt1 gene expression. |
2002 |
Nucleic Acids Res. Suppl. |
pmid:12903179
|
Ginjala V et al. |
Multiple cis elements within the Igf2/H19 insulator domain organize a distance-dependent silencer. A cautionary note. |
2002 |
J. Biol. Chem. |
pmid:11777900
|
Cabral AL et al. |
Regulation of the cellular prion protein gene expression depends on chromatin conformation. |
2002 |
J. Biol. Chem. |
pmid:11739375
|
Park SH et al. |
Transcriptional regulation of the transforming growth factor beta type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells. |
2002 |
J. Biol. Chem. |
pmid:11744689
|
Suenaga M et al. |
Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells. |
2002 |
Int. J. Cancer |
pmid:11807787
|
Gurova KV et al. |
Expression of prostate specific antigen (PSA) is negatively regulated by p53. |
2002 |
Oncogene |
pmid:11791186
|
Maeda Y et al. |
Repression of hepatocyte nuclear factor 4alpha tumor suppressor p53: involvement of the ligand-binding domain and histone deacetylase activity. |
2002 |
Mol. Endocrinol. |
pmid:11818510
|
Singal R et al. |
Methylation of promoter proximal-transcribed sequences of an embryonic globin gene inhibits transcription in primary erythroid cells and promotes formation of a cell type-specific methyl cytosine binding complex. |
2002 |
J. Biol. Chem. |
pmid:11684679
|
Mikkelsen IM et al. |
Activation of the gamma-glutamyltransferase promoter 2 in the rat colon carcinoma cell line CC531 by histone deacetylase inhibitors is mediated through the Sp1 binding motif. |
2002 |
Biochem. Pharmacol. |
pmid:12123752
|
Petti MC et al. |
Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies. |
2002 |
Blood |
pmid:12130525
|
Avram D et al. |
COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein. |
2002 |
Biochem. J. |
pmid:12196208
|
Guo Y et al. |
Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion. |
2002 |
J. Biol. Chem. |
pmid:12198113
|
Wittich S et al. |
Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells. |
2002 |
J. Med. Chem. |
pmid:12109913
|
Toyooka S et al. |
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures. |
2002 |
Clin. Cancer Res. |
pmid:12114433
|
Choi HS et al. |
Trichostatin A, a histone deacetylase inhibitor, activates the IGFBP-3 promoter by upregulating Sp1 activity in hepatoma cells: alteration of the Sp1/Sp3/HDAC1 multiprotein complex. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12200149
|
Maecker HL et al. |
Epigenetic changes in tumor Fas levels determine immune escape and response to therapy. |
2002 |
Cancer Cell |
pmid:12204534
|
Fang D et al. |
Selective down-regulation of tyrosinase family gene TYRP1 by inhibition of the activity of melanocyte transcription factor, MITF. |
2002 |
Nucleic Acids Res. |
pmid:12136092
|
Zschocke J et al. |
Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells. |
2002 |
J. Biol. Chem. |
pmid:12138116
|
Yu Z et al. |
Histone deacetylases augment cytokine induction of the iNOS gene. |
2002 |
J. Am. Soc. Nephrol. |
pmid:12138131
|
Li J et al. |
Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. |
2002 |
Mol. Cell. Biol. |
pmid:12138181
|
Aapola U et al. |
Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity. |
2002 |
Nucleic Acids Res. |
pmid:12177302
|
Chang TH and Szabo E |
Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. |
2002 |
Clin. Cancer Res. |
pmid:11948134
|
Ventura A et al. |
The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter. |
2002 |
J. Biol. Chem. |
pmid:11948181
|
Gradoville L et al. |
Protein kinase C-independent activation of the Epstein-Barr virus lytic cycle. |
2002 |
J. Virol. |
pmid:11991990
|
Uesato S et al. |
Novel histone deacetylase inhibitors: N-hydroxycarboxamides possessing a terminal bicyclic aryl group. |
2002 |
Bioorg. Med. Chem. Lett. |
pmid:11992774
|
Nambiar MP et al. |
Effect of trichostatin A on human T cells resembles signaling abnormalities in T cells of patients with systemic lupus erythematosus: a new mechanism for TCR zeta chain deficiency and abnormal signaling. |
2002 |
J. Cell. Biochem. |
pmid:11967985
|
Fu M et al. |
Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. |
2002 |
Mol. Cell. Biol. |
pmid:11971970
|
Sirchia SM et al. |
Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer. |
2002 |
Cancer Res. |
pmid:11980632
|
Milutinovic S et al. |
Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification. |
2002 |
J. Biol. Chem. |
pmid:11929879
|
Williams RS et al. |
A common mechanism of action for three mood-stabilizing drugs. |
2002 |
Nature |
pmid:12015604
|
Veilleux S and Boissonneault G |
Dynamics of reporter gene stimulation by HMG box proteins. |
2002 |
DNA Cell Biol. |
pmid:12015897
|
Huang HC et al. |
Geldanamycin inhibits trichostatin A-induced cell death and histone H4 hyperacetylation in COS-7 cells. |
2002 |
Life Sci. |
pmid:12002521
|
Chiocca S et al. |
Histone deacetylase 1 inactivation by an adenovirus early gene product. |
2002 |
Curr. Biol. |
pmid:11937030
|
Weston AD et al. |
Requirement for RAR-mediated gene repression in skeletal progenitor differentiation. |
2002 |
J. Cell Biol. |
pmid:12105181
|
Toyooka S et al. |
Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. |
2002 |
Oncogene |
pmid:12082623
|
Maehara K et al. |
Effects of histone acetylation on transcriptional regulation of manganese superoxide dismutase gene. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12083788
|
Iezzi S et al. |
Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12032356
|
Nielsen J |
Combinatorial synthesis of natural products. |
2002 |
Curr Opin Chem Biol |
pmid:12023109
|
Mikkelsen IM et al. |
The expression of gamma-glutamyltransferase in rat colon carcinoma cells is distinctly regulated during differentiation and oxidative stress. |
2002 |
Mol. Cell. Biochem. |
pmid:12030384
|
Bharadwaj S and Prasad GL |
Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. |
2002 |
Cancer Lett. |
pmid:12065096
|
Ito K et al. |
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12070353
|
Katula KS et al. |
Cell cycle specific changes in the human cyclin B1 gene regulatory region as revealed by response to trichostatin A. |
2002 |
Arch. Biochem. Biophys. |
pmid:12054478
|
Wang XQ et al. |
Histone deacetylase inhibition results in decreased macrophage CD9 expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12056820
|
Rahmani M et al. |
The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process. |
2002 |
Exp. Cell Res. |
pmid:12061815
|
Woo SH et al. |
Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors. |
2002 |
J. Med. Chem. |
pmid:12061890
|
Chen Y et al. |
On the epigenetic regulation of the human reelin promoter. |
2002 |
Nucleic Acids Res. |
pmid:12087179
|
Zhang Y and Dufau ML |
Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex. |
2002 |
J. Biol. Chem. |
pmid:12091390
|
Danbara M et al. |
DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines. |
2002 |
Mol. Immunol. |
pmid:12044782
|
Lin HM et al. |
Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors. |
2002 |
J. Biol. Chem. |
pmid:12048199
|
Scott GK et al. |
Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen. |
2002 |
Mol. Cancer Ther. |
pmid:12477051
|
Quivy V et al. |
Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies. |
2002 |
J. Virol. |
pmid:12368351
|
Smith WL and Edlind TD |
Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation. |
2002 |
Antimicrob. Agents Chemother. |
pmid:12384361
|
Harada K et al. |
Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. |
2002 |
Cancer Res. |
pmid:12384554
|
Im H et al. |
Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain. |
2002 |
Biochemistry |
pmid:12484752
|
Zhang J et al. |
Establishment of transcriptional competence in early and late S phase. |
2002 |
Nature |
pmid:12432398
|
Gong XQ and Li L |
Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation. |
2002 |
J. Biol. Chem. |
pmid:11809751
|
Kostyniuk CL et al. |
The ubiquitous and tissue specific promoters of the human SRC gene are repressed by inhibitors of histone deacetylases. |
2002 |
Oncogene |
pmid:12214274
|
Rössig L et al. |
Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis. |
2002 |
Circ. Res. |
pmid:12411399
|
Hall IM et al. |
Establishment and maintenance of a heterochromatin domain. |
2002 |
Science |
pmid:12215653
|
Lynch CA et al. |
Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. |
2002 |
Mol. Cancer |
pmid:12234381
|
Bereshchenko OR et al. |
Acetylation inactivates the transcriptional repressor BCL6. |
2002 |
Nat. Genet. |
pmid:12402037
|
Hauser C et al. |
Activation of the mouse histone deacetylase 1 gene by cooperative histone phosphorylation and acetylation. |
2002 |
Mol. Cell. Biol. |
pmid:12391151
|
Westendorf JJ et al. |
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. |
2002 |
Mol. Cell. Biol. |
pmid:12391164
|
Hoshimoto A et al. |
Caprylic acid and medium-chain triglycerides inhibit IL-8 gene transcription in Caco-2 cells: comparison with the potent histone deacetylase inhibitor trichostatin A. |
2002 |
Br. J. Pharmacol. |
pmid:12010777
|
McGuinness MC et al. |
Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. |
2001 Sep-Oct |
Mol. Genet. Metab. |
pmid:11592822
|
Rombouts K et al. |
Trichostatin A, lead compound for development of antifibrogenic drugs. |
2001 Jul-Sep |
Acta Gastroenterol. Belg. |
pmid:11680040
|
Yin L et al. |
Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. |
2001 |
J. Biol. Chem. |
pmid:11572859
|
Zelivianski S et al. |
Multipathways for transdifferentiation of human prostate cancer cells into neuroendocrine-like phenotype. |
2001 |
Biochim. Biophys. Acta |
pmid:11389966
|
Chang YC et al. |
Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. |
2001 |
Mol. Cell. Biol. |
pmid:11158299
|