Abderrahmani A et al. |
The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1). |
2001 |
Mol. Cell. Biol. |
pmid:11585908
|
Yoshida M et al. |
Histone deacetylase as a new target for cancer chemotherapy. |
2001 |
Cancer Chemother. Pharmacol. |
pmid:11587361
|
Jung M |
Inhibitors of histone deacetylase as new anticancer agents. |
2001 |
Curr. Med. Chem. |
pmid:11562279
|
Ashburner BP et al. |
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. |
2001 |
Mol. Cell. Biol. |
pmid:11564889
|
Sachs LM et al. |
Involvement of histone deacetylase at two distinct steps in gene regulation during intestinal development in Xenopus laevis. |
2001 |
Dev. Dyn. |
pmid:11668605
|
Amann JM et al. |
ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain. |
2001 |
Mol. Cell. Biol. |
pmid:11533236
|
Sourlingas TG et al. |
Histone deacetylase inhibitors induce apoptosis in peripheral blood lymphocytes along with histone H4 acetylation and the expression of the linker histone variant, H1 degrees. |
2001 |
Eur. J. Cell Biol. |
pmid:11824792
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A induce apoptosis through an increase of the bcl-2-related protein Bad. |
2001 |
Brain Tumor Pathol |
pmid:11908866
|
Benjamin D and Jost JP |
Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
2001 |
Nucleic Acids Res. |
pmid:11522830
|
Hatama S et al. |
Reactivation of feline foamy virus from a chronically infected feline renal cell line by trichostatin A. |
2001 |
Virology |
pmid:11336556
|
Viollet B et al. |
Embryonic but not postnatal reexpression of hepatocyte nuclear factor 1alpha (HNF1alpha) can reactivate the silent phenylalanine hydroxylase gene in HNF1alpha-deficient hepatocytes. |
2001 |
Mol. Cell. Biol. |
pmid:11340160
|
Nakamura M et al. |
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor. |
2001 |
J. Cell. Physiol. |
pmid:11319763
|
Xu D et al. |
Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11274400
|
Seth KA and Majzoub JA |
Repressor element silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) can act as an enhancer as well as a repressor of corticotropin-releasing hormone gene transcription. |
2001 |
J. Biol. Chem. |
pmid:11278361
|
Matsuda E et al. |
Targeting of Krüppel-associated box-containing zinc finger proteins to centromeric heterochromatin. Implication for the gene silencing mechanisms. |
2001 |
J. Biol. Chem. |
pmid:11278721
|
Kim MS et al. |
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. |
2001 |
Nat. Med. |
pmid:11283670
|
Vigushin DM et al. |
Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo. |
2001 |
Clin. Cancer Res. |
pmid:11309348
|
Magdinier F and Wolffe AP |
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11309512
|
Rashid SF et al. |
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. |
2001 |
Oncogene |
pmid:11313934
|
Osborne A et al. |
Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. |
2001 |
Mol. Cell. Biol. |
pmid:11533238
|
Chen C et al. |
Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites. |
2001 |
J. Biol. Chem. |
pmid:11013250
|
Ullerås E et al. |
Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer. |
2001 |
Exp. Cell Res. |
pmid:11640883
|
Shestakova E et al. |
Inhibition of histone deacetylation induces constitutive derepression of the beta interferon promoter and confers antiviral activity. |
2001 |
J. Virol. |
pmid:11238870
|
Kuwahara K et al. |
The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. |
2001 |
Mol. Cell. Biol. |
pmid:11238943
|
Meier JL |
Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator. |
2001 |
J. Virol. |
pmid:11160656
|
Kuusisto E et al. |
Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11162503
|
Grandjean V et al. |
Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain. |
2001 |
FEBS Lett. |
pmid:11163765
|
Lizcano F et al. |
Cell type-specific roles of histone deacetylase in TR ligand-independent transcriptional repression. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11165035
|
Nervi C et al. |
Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity. |
2001 |
Cancer Res. |
pmid:11245412
|
Rombouts K et al. |
Trichostatin A, lead compound for development of antifibrogenic drugs. |
2001 Jul-Sep |
Acta Gastroenterol. Belg. |
pmid:11680040
|
McGuinness MC et al. |
Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. |
2001 Sep-Oct |
Mol. Genet. Metab. |
pmid:11592822
|
Sanyal S et al. |
Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. |
2002 |
J. Biol. Chem. |
pmid:11705994
|
Galasinski SC et al. |
Global regulation of post-translational modifications on core histones. |
2002 |
J. Biol. Chem. |
pmid:11709551
|
Zarnegar R et al. |
Increasing the effectiveness of radioactive iodine therapy in the treatment of thyroid cancer using Trichostatin A, a histone deacetylase inhibitor. |
2002 |
Surgery |
pmid:12490845
|
Chen T et al. |
Histone acetylation is involved in hsp70 gene transcription regulation in Drosophila melanogaster. |
2002 |
Arch. Biochem. Biophys. |
pmid:12464268
|
Rombouts K et al. |
Actin filament formation, reorganization and migration are impaired in hepatic stellate cells under influence of trichostatin A, a histone deacetylase inhibitor. |
2002 |
J. Hepatol. |
pmid:12445420
|
Guo WH et al. |
Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor. |
2002 |
Oncogene |
pmid:12447699
|
Marin-Husstege M et al. |
Histone deacetylase activity is necessary for oligodendrocyte lineage progression. |
2002 |
J. Neurosci. |
pmid:12451133
|
Wang ZM et al. |
Trichostatin A inhibits proliferation and induces expression of p21WAF and p27 in human brain tumor cell lines. |
2002 |
Ai Zheng |
pmid:12508652
|
Duharcourt S and Yao MC |
Role of histone deacetylation in developmentally programmed DNA rearrangements in Tetrahymena thermophila. |
2002 |
Eukaryotic Cell |
pmid:12455963
|
Strait KA et al. |
Cell cycle blockade and differentiation of ovarian cancer cells by the histone deacetylase inhibitor trichostatin A are associated with changes in p21, Rb, and Id proteins. |
2002 |
Mol. Cancer Ther. |
pmid:12479699
|
Blagosklonny MV et al. |
Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity. |
2002 |
Mol. Cancer Ther. |
pmid:12481415
|
Drewell RA et al. |
Methylation-dependent silencing at the H19 imprinting control region by MeCP2. |
2002 |
Nucleic Acids Res. |
pmid:11861904
|
Murphy JC et al. |
Control of cytomegalovirus lytic gene expression by histone acetylation. |
2002 |
EMBO J. |
pmid:11867539
|
Kim JY et al. |
Probing lysine acetylation with a modification-specific marker ion using high-performance liquid chromatography/electrospray-mass spectrometry with collision-induced dissociation. |
2002 |
Anal. Chem. |
pmid:12433071
|
Elaut G et al. |
Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes. |
2002 |
Drug Metab. Dispos. |
pmid:12433798
|
Remiszewski SW et al. |
Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates. |
2002 |
J. Med. Chem. |
pmid:11831887
|
Kiefer SM et al. |
Murine Sall1 represses transcription by recruiting a histone deacetylase complex. |
2002 |
J. Biol. Chem. |
pmid:11836251
|
Roddie PH et al. |
Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1. |
2002 |
Leukemia |
pmid:11840267
|
Taniura S et al. |
Transcriptional regulation of cyclooxygenase-1 by histone deacetylase inhibitors in normal human astrocyte cells. |
2002 |
J. Biol. Chem. |
pmid:11877441
|
Heltweg B and Jung M |
A microplate reader-based nonisotopic histone deacetylase activity assay. |
2002 |
Anal. Biochem. |
pmid:11878795
|
Kamitani H et al. |
Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced. |
2002 |
Neuro-oncology |
pmid:11916500
|
Kishikawa S et al. |
Roles of histone acetylation in the Dnmt1 gene expression. |
2002 |
Nucleic Acids Res. Suppl. |
pmid:12903179
|
Ginjala V et al. |
Multiple cis elements within the Igf2/H19 insulator domain organize a distance-dependent silencer. A cautionary note. |
2002 |
J. Biol. Chem. |
pmid:11777900
|
Cabral AL et al. |
Regulation of the cellular prion protein gene expression depends on chromatin conformation. |
2002 |
J. Biol. Chem. |
pmid:11739375
|
Park SH et al. |
Transcriptional regulation of the transforming growth factor beta type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells. |
2002 |
J. Biol. Chem. |
pmid:11744689
|
Suenaga M et al. |
Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells. |
2002 |
Int. J. Cancer |
pmid:11807787
|
Gurova KV et al. |
Expression of prostate specific antigen (PSA) is negatively regulated by p53. |
2002 |
Oncogene |
pmid:11791186
|
Maeda Y et al. |
Repression of hepatocyte nuclear factor 4alpha tumor suppressor p53: involvement of the ligand-binding domain and histone deacetylase activity. |
2002 |
Mol. Endocrinol. |
pmid:11818510
|
Singal R et al. |
Methylation of promoter proximal-transcribed sequences of an embryonic globin gene inhibits transcription in primary erythroid cells and promotes formation of a cell type-specific methyl cytosine binding complex. |
2002 |
J. Biol. Chem. |
pmid:11684679
|
Choi HS et al. |
Trichostatin A, a histone deacetylase inhibitor, activates the IGFBP-3 promoter by upregulating Sp1 activity in hepatoma cells: alteration of the Sp1/Sp3/HDAC1 multiprotein complex. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12200149
|
Maecker HL et al. |
Epigenetic changes in tumor Fas levels determine immune escape and response to therapy. |
2002 |
Cancer Cell |
pmid:12204534
|
Fang D et al. |
Selective down-regulation of tyrosinase family gene TYRP1 by inhibition of the activity of melanocyte transcription factor, MITF. |
2002 |
Nucleic Acids Res. |
pmid:12136092
|
Zschocke J et al. |
Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells. |
2002 |
J. Biol. Chem. |
pmid:12138116
|
Yu Z et al. |
Histone deacetylases augment cytokine induction of the iNOS gene. |
2002 |
J. Am. Soc. Nephrol. |
pmid:12138131
|
Li J et al. |
Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. |
2002 |
Mol. Cell. Biol. |
pmid:12138181
|
Aapola U et al. |
Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity. |
2002 |
Nucleic Acids Res. |
pmid:12177302
|
Chang TH and Szabo E |
Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. |
2002 |
Clin. Cancer Res. |
pmid:11948134
|
Ventura A et al. |
The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter. |
2002 |
J. Biol. Chem. |
pmid:11948181
|
Gradoville L et al. |
Protein kinase C-independent activation of the Epstein-Barr virus lytic cycle. |
2002 |
J. Virol. |
pmid:11991990
|
Uesato S et al. |
Novel histone deacetylase inhibitors: N-hydroxycarboxamides possessing a terminal bicyclic aryl group. |
2002 |
Bioorg. Med. Chem. Lett. |
pmid:11992774
|
Nambiar MP et al. |
Effect of trichostatin A on human T cells resembles signaling abnormalities in T cells of patients with systemic lupus erythematosus: a new mechanism for TCR zeta chain deficiency and abnormal signaling. |
2002 |
J. Cell. Biochem. |
pmid:11967985
|
Fu M et al. |
Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. |
2002 |
Mol. Cell. Biol. |
pmid:11971970
|
Sirchia SM et al. |
Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer. |
2002 |
Cancer Res. |
pmid:11980632
|
Milutinovic S et al. |
Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification. |
2002 |
J. Biol. Chem. |
pmid:11929879
|
Williams RS et al. |
A common mechanism of action for three mood-stabilizing drugs. |
2002 |
Nature |
pmid:12015604
|
Veilleux S and Boissonneault G |
Dynamics of reporter gene stimulation by HMG box proteins. |
2002 |
DNA Cell Biol. |
pmid:12015897
|
Huang HC et al. |
Geldanamycin inhibits trichostatin A-induced cell death and histone H4 hyperacetylation in COS-7 cells. |
2002 |
Life Sci. |
pmid:12002521
|
Mikkelsen IM et al. |
The expression of gamma-glutamyltransferase in rat colon carcinoma cells is distinctly regulated during differentiation and oxidative stress. |
2002 |
Mol. Cell. Biochem. |
pmid:12030384
|
Bharadwaj S and Prasad GL |
Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. |
2002 |
Cancer Lett. |
pmid:12065096
|
Ito K et al. |
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12070353
|
Katula KS et al. |
Cell cycle specific changes in the human cyclin B1 gene regulatory region as revealed by response to trichostatin A. |
2002 |
Arch. Biochem. Biophys. |
pmid:12054478
|
Wang XQ et al. |
Histone deacetylase inhibition results in decreased macrophage CD9 expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12056820
|
Rahmani M et al. |
The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process. |
2002 |
Exp. Cell Res. |
pmid:12061815
|
Woo SH et al. |
Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors. |
2002 |
J. Med. Chem. |
pmid:12061890
|
Chen Y et al. |
On the epigenetic regulation of the human reelin promoter. |
2002 |
Nucleic Acids Res. |
pmid:12087179
|
Zhang Y and Dufau ML |
Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex. |
2002 |
J. Biol. Chem. |
pmid:12091390
|
Danbara M et al. |
DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines. |
2002 |
Mol. Immunol. |
pmid:12044782
|
Lin HM et al. |
Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors. |
2002 |
J. Biol. Chem. |
pmid:12048199
|
Quivy V et al. |
Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies. |
2002 |
J. Virol. |
pmid:12368351
|
Smith WL and Edlind TD |
Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation. |
2002 |
Antimicrob. Agents Chemother. |
pmid:12384361
|
Harada K et al. |
Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. |
2002 |
Cancer Res. |
pmid:12384554
|
Im H et al. |
Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain. |
2002 |
Biochemistry |
pmid:12484752
|
Zhang J et al. |
Establishment of transcriptional competence in early and late S phase. |
2002 |
Nature |
pmid:12432398
|
Gong XQ and Li L |
Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation. |
2002 |
J. Biol. Chem. |
pmid:11809751
|
Kostyniuk CL et al. |
The ubiquitous and tissue specific promoters of the human SRC gene are repressed by inhibitors of histone deacetylases. |
2002 |
Oncogene |
pmid:12214274
|
Rössig L et al. |
Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis. |
2002 |
Circ. Res. |
pmid:12411399
|
Hall IM et al. |
Establishment and maintenance of a heterochromatin domain. |
2002 |
Science |
pmid:12215653
|
Lynch CA et al. |
Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. |
2002 |
Mol. Cancer |
pmid:12234381
|
Bereshchenko OR et al. |
Acetylation inactivates the transcriptional repressor BCL6. |
2002 |
Nat. Genet. |
pmid:12402037
|