Kotantaki P and Mosialos G |
The expression of tumor suppressor gene Cyld is upregulated by histone deacetylace inhibitors in human hepatocellular carcinoma cell lines. |
2016 |
Cell Biochem. Funct. |
pmid:27570065
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DÃaz-Núñez M et al. |
Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity. |
2016 |
BMC Cancer |
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Sugiyama KI et al. |
Epigenetic mutagen as histone modulator can be detected by yeast flocculation. |
2016 |
Mutagenesis |
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Zhang XF et al. |
Trichostatin A Enhances the Apoptotic Potential of Palladium Nanoparticles in Human Cervical Cancer Cells. |
2016 |
Int J Mol Sci |
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Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer. |
2016 |
Chem. Biol. Interact. |
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Huang H et al. |
Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function. |
2016 |
Cell. Mol. Immunol. |
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Histone deacetylase inhibitor-induced cell death in bladder cancer is associated with chromatin modification and modifying protein expression: A proteomic approach. |
2016 |
Int. J. Oncol. |
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Duclot F et al. |
Trichostatin A (TSA) facilitates formation of partner preference in male prairie voles (Microtus ochrogaster). |
2016 |
Horm Behav |
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Toki S et al. |
The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation. |
2016 |
Thorax |
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Chen J et al. |
Histone Deacetylase Inhibitors Trichostatin A and MCP30 Relieve Benzene-Induced Hematotoxicity via Restoring Topoisomerase IIα. |
2016 |
PLoS ONE |
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Histone Acetylation Induced Transformation of B-DNA to Z-DNA in Cells Probed through FT-IR Spectroscopy. |
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Anal. Chem. |
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Transient resistance to DNA damaging agents is associated with expression of microRNAs-135b and -196b in human leukemia cell lines. |
2016 |
Int J Biochem Mol Biol |
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Methylation of tumor suppressor gene CDH13 and SHP1 promoters and their epigenetic regulation by the UHRF1/PRMT5 complex in endometrial carcinoma. |
2016 |
Gynecol. Oncol. |
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Yeh BW et al. |
Histone deacetylase inhibitor trichostatin A resensitizes gemcitabine resistant urothelial carcinoma cells via suppression of TG-interacting factor. |
2016 |
Toxicol. Appl. Pharmacol. |
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Asgar MA et al. |
Synergistic anticancer effects of cisplatin and histone deacetylase inhibitors (SAHA and TSA) on cholangiocarcinoma cell lines. |
2016 |
Int. J. Oncol. |
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Histone deacetylase–mediated silencing of AMWAP expression contributes to cisplatin nephrotoxicity. |
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Kidney Int. |
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Buffalo (Bubalus bubalis) SCNT embryos produced from somatic cells isolated from frozen-thawed semen: effect of trichostatin A on the in vitro and in vivo developmental potential, quality and epigenetic status. |
2016 |
Zygote |
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Han Y et al. |
Murine hematopoietic stem cell dormancy controlled by induction of a novel short form of PSF1 by histone deacetylase inhibitors. |
2015 |
Exp. Cell Res. |
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Identification of Critical Elements for Regulation of Inorganic Pyrophosphatase (PPA1) in MCF7 Breast Cancer Cells. |
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PLoS ONE |
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SCL/TAL1-mediated transcriptional network enhances megakaryocytic specification of human embryonic stem cells. |
2015 |
Mol. Ther. |
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A traditional Chinese medicine, Lujiao prescription, as a potential therapy for hypertrophic cardiomyocytes by acting on histone acetylation. |
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J Chin Med Assoc |
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IL-4 Modulates Macrophage Polarization in Ankylosing Spondylitis. |
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Cell. Physiol. Biochem. |
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Identification of novel pathways and molecules able to down-regulate PHOX2B gene expression by in vitro drug screening approaches in neuroblastoma cells. |
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Exp. Cell Res. |
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DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells. |
2015 |
BMC Cancer |
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Trichostatin A-mediated epigenetic transformation of adult bone marrow-derived mesenchymal stem cells biases the in vitro developmental capability, quality, and pluripotency extent of porcine cloned embryos. |
2015 |
Biomed Res Int |
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Hou H et al. |
Influence of intra-articular administration of trichostatin a on autologous osteochondral transplantation in a rabbit model. |
2015 |
Biomed Res Int |
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Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men. |
2015 |
Epigenetics |
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Ganatra DA et al. |
Association of histone acetylation at the ACTA2 promoter region with epithelial mesenchymal transition of lens epithelial cells. |
2015 |
Eye (Lond) |
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Role of epigenetic reprogramming in hematopoietic stem cell function. |
2015 |
Curr. Opin. Hematol. |
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Brainstem brain-derived neurotrophic factor signaling is required for histone deacetylase inhibitor-induced pain relief. |
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Mol. Pharmacol. |
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AtEAF1 is a potential platform protein for Arabidopsis NuA4 acetyltransferase complex. |
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BMC Plant Biol. |
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Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue. |
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Neuropsychopharmacology |
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PTPRD is homozygously deleted and epigenetically downregulated in human hepatocellular carcinomas. |
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OMICS |
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Prolonged re-expression of the hypermethylated gene EPB41L3 using artificial transcription factors and epigenetic drugs. |
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Epigenetics |
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Lactogenic hormone stimulation and epigenetic control of L-amino acid oxidase expression in lactating mammary glands. |
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Potential role of adolescent alcohol exposure-induced amygdaloid histone modifications in anxiety and alcohol intake during adulthood. |
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Postmitotic Expression of SOD1(G93A) Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation. |
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Mediators Inflamm. |
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Generation of cloned mice from adult neurons by direct nuclear transfer. |
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Biol. Reprod. |
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Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and promotes apoptosis of esophageal squamous cell lines. |
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Mol Med Rep |
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Impact of viral activators and epigenetic regulators on HIV-1 LTRs containing naturally occurring single nucleotide polymorphisms. |
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Biomed Res Int |
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Trichostatin A Protects Against Experimental Acute-on-Chronic Liver Failure in Rats Through Regulating the Acetylation of Nuclear Factor-κB. |
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Inflammation |
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Assessment of the effect of trichostatin A on HeLa cells through FT-IR spectroscopy. |
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Anal. Chem. |
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Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth. |
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Cell Death Differ. |
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RASSF5A, a candidate tumor suppressor, is epigenetically inactivated in esophageal squamous cell carcinoma. |
2015 |
Clin. Exp. Metastasis |
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Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells. |
2015 |
Pituitary |
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Post-training, intrahippocampal HDAC inhibition differentially impacts neural circuits underlying spatial memory in adult and aged mice. |
2015 |
Hippocampus |
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Dual roles of histone H3 lysine 9 acetylation in human embryonic stem cell pluripotency and neural differentiation. |
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J. Biol. Chem. |
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Downregulation of the microRNA-1/133a cluster enhances cancer cell migration and invasion in lung-squamous cell carcinoma via regulation of Coronin1C. |
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Trichostatin A modulates intracellular reactive oxygen species through SOD2 and FOXO1 in human bone marrow-mesenchymal stem cells. |
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Cell Biochem. Funct. |
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Histone deacetylase regulates trypsin activation, inflammation, and tissue damage in acute pancreatitis in mice. |
2015 |
Dig. Dis. Sci. |
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Changes of spontaneous parthenogenetic activation and development potential of golden hamster oocytes during the aging process. |
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Acta Histochem. |
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HDAC4 degradation mediates HDAC inhibition-induced protective effects against hypoxia/reoxygenation injury. |
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J. Cell. Physiol. |
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Increased Histone Deacetylase Activity Involved in the Suppressed Invasion of Cancer Cells Survived from ALA-Mediated Photodynamic Treatment. |
2015 |
Int J Mol Sci |
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Ex vivo expansion of human mobilized peripheral blood stem cells using epigenetic modifiers. |
2015 |
Transfusion |
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Effect of epigenetic modification with trichostatin A and S-adenosylhomocysteine on developmental competence and POU5F1-EGFP expression of interspecies cloned embryos in dog. |
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Zygote |
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Trichostatin A affects the secretion pathways of beta and intestinal endocrine cells. |
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Exp. Cell Res. |
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A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. |
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Arch. Toxicol. |
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Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling. |
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Neurotoxicology |
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Schlörmann W et al. |
Influence of miRNA-106b and miRNA-135a on butyrate-regulated expression of p21 and Cyclin D2 in human colon adenoma cells. |
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Genes Nutr |
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Acetylation-dependent function of human single-stranded DNA binding protein 1. |
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Nucleic Acids Res. |
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Arsenic exposure causes epigenetic dysregulation of IL-8 expression leading to proneoplastic changes in kidney cells. |
2015 |
Toxicol. Lett. |
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Histone deacetylase inhibitor attenuates neurotoxicity of clioquinol in PC12 cells. |
2015 |
Toxicology |
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Deacetylase inhibitors repress STAT5-mediated transcription by interfering with bromodomain and extra-terminal (BET) protein function. |
2015 |
Nucleic Acids Res. |
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Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases. |
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Chem. Biol. |
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Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts. |
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Cardiovasc. Res. |
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Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells. |
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Biomolecules |
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HDAC inhibitors induce epithelial-mesenchymal transition in colon carcinoma cells. |
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Oncol. Rep. |
pmid:25813246
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Histone deacetylases inhibitors effects on Cryptococcus neoformans major virulence phenotypes. |
2015 |
Virulence |
pmid:26103530
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Sugimoto H et al. |
Production of somatic cell nuclear transfer embryos using in vitro-grown and in vitro-matured oocytes in rabbits. |
2015 |
Zygote |
pmid:24666637
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Li Z et al. |
DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer. |
2015 |
Gastric Cancer |
pmid:24481854
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The effects of histone deacetylase inhibitors on glioblastoma-derived stem cells. |
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J. Mol. Neurosci. |
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Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. |
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J. Cell. Biochem. |
pmid:25510910
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Ma L et al. |
HDAC5-mTORC1 Interaction in Differential Regulation of Ghrelin and Nucleobindin 2 (NUCB2)/Nesfatin-1. |
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Mol. Endocrinol. |
pmid:26357899
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Histone deacetylase inhibitors relieve morphine resistance in neuropathic pain after peripheral nerve injury. |
2015 |
J. Pharmacol. Sci. |
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Effect of histone deacetylase on prostate carcinoma. |
2015 |
Int J Clin Exp Pathol |
pmid:26823840
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Uchida H and Ito S |
Differential regulation of expression of RNA-editing enzymes, ADAR1 and ADAR2, by 5-aza-2'-deoxycytidine and trichostatin A in human neuronal SH-SY5Y cells. |
2015 |
Neuroreport |
pmid:26485095
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Barr MP et al. |
VEGF-mediated cell survival in non-small-cell lung cancer: implications for epigenetic targeting of VEGF receptors as a therapeutic approach. |
2015 |
Epigenomics |
pmid:26479311
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Liu J and Li Y |
Trichostatin A and Tamoxifen inhibit breast cancer cell growth by miR-204 and ERα reducing AKT/mTOR pathway. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:26436206
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Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis. |
2015 |
Arthritis Res. Ther. |
pmid:26408027
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Rolando M et al. |
Contractile actin cables induced by Bacillus anthracis lethal toxin depend on the histone acetylation machinery. |
2015 |
Cytoskeleton (Hoboken) |
pmid:26403219
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Feng W et al. |
Combination of HDAC inhibitor TSA and silibinin induces cell cycle arrest and apoptosis by targeting survivin and cyclinB1/Cdk1 in pancreatic cancer cells. |
2015 |
Biomed. Pharmacother. |
pmid:26349994
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Li YL et al. |
Downregulation of growth differentiation factor-15 in trichostatin A-induced apoptosis could play a role in progression of gastric cancer. |
2015 |
Int J Clin Exp Pathol |
pmid:26339382
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Histone Deacetylase Inhibitors Inhibit the Proliferation of Gallbladder Carcinoma Cells by Suppressing AKT/mTOR Signaling. |
2015 |
PLoS ONE |
pmid:26287365
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Perez-Janices N et al. |
Differential involvement of RASSF2 hypermethylation in breast cancer subtypes and their prognosis. |
2015 |
Oncotarget |
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Histone acetylation regulates prostate ductal morphogenesis through a bone morphogenetic protein-dependent mechanism. |
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Dev. Dyn. |
pmid:26283270
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Analysis of an independent tumor suppressor locus telomeric to Tp53 suggested Inpp5k and Myo1c as novel tumor suppressor gene candidates in this region. |
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BMC Genet. |
pmid:26170120
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[Association of irradiation-induced hippocampal neurogenesis impairment with histone H3 acetylation]. |
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Zhonghua Yi Xue Za Zhi |
pmid:26168675
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Dnmt3l-knockout donor cells improve somatic cell nuclear transfer reprogramming efficiency. |
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Reproduction |
pmid:26159833
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MYCNOS functions as an antisense RNA regulating MYCN. |
2015 |
RNA Biol |
pmid:26156430
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Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo. |
2015 |
Exp. Lung Res. |
pmid:26151196
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Evaluation of Epigenetic Drug Targeting of Heterogenous Tumor Cell Fractions Using Potential Biomarkers of Response in Ovarian Cancer. |
2015 |
Clin. Cancer Res. |
pmid:26130461
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Extracellularly secreted APE1/Ref-1 triggers apoptosis in triple-negative breast cancer cells via RAGE binding, which is mediated through acetylation. |
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Oncotarget |
pmid:26125438
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Thangavel J et al. |
Epigenetic modifiers reduce inflammation and modulate macrophage phenotype during endotoxemia-induced acute lung injury. |
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J. Cell. Sci. |
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Trichostatin A reduces GnRH mRNA expression with a concomitant increase in retinaldehyde dehydrogenase in GnRH-producing neurons. |
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Mol. Cell. Endocrinol. |
pmid:26116234
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Trichostatin A, a histone deacetylase inhibitor, modulates unloaded-induced skeletal muscle atrophy. |
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J. Appl. Physiol. |
pmid:26112243
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Liu J et al. |
Trichostatin A suppresses lung adenocarcinoma development in Grg1 overexpressing transgenic mice. |
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Biochem. Biophys. Res. Commun. |
pmid:26086099
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Huang J et al. |
Trichostatin A reduces cisplatin-induced ototoxicity through the STAT6 signaling pathway. |
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Int. J. Mol. Med. |
pmid:26080623
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Huan Y et al. |
Epigenetic Modification Agents Improve Gene-Specific Methylation Reprogramming in Porcine Cloned Embryos. |
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PLoS ONE |
pmid:26068219
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Huan Y et al. |
Epigenetic Modification of Cloned Embryos Improves Nanog Reprogramming in Pigs. |
2015 |
Cell Reprogram |
pmid:26053519
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Optimization of histone deacetylase inhibitor activity in non-secosteroidal vitamin D-receptor agonist hybrids. |
2015 |
Bioorg. Med. Chem. |
pmid:26048026
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