Arany I et al. |
Epigenetic modifiers exert renal toxicity through induction of p66shc. |
2011 |
Anticancer Res. |
pmid:21965735
|
Majumdar G et al. |
Panhistone deacetylase inhibitors inhibit proinflammatory signaling pathways to ameliorate interleukin-18-induced cardiac hypertrophy. |
2011 |
Physiol. Genomics |
pmid:21954451
|
Tsai KW et al. |
Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer. |
2011 |
Int. J. Cancer |
pmid:21960261
|
Ohtani K et al. |
Epigenetic regulation of endothelial lineage committed genes in pro-angiogenic hematopoietic and endothelial progenitor cells. |
2011 |
Circ. Res. |
pmid:21980126
|
Hagiwara H et al. |
Histone deacetylase inhibitor trichostatin A enhances myogenesis by coordinating muscle regulatory factors and myogenic repressors. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:22019851
|
Jafari S et al. |
Epigenetic modification does not determine the time of POU5F1 transcription activation in cloned bovine embryos. |
2011 |
J. Assist. Reprod. Genet. |
pmid:22020531
|
Tseng AS et al. |
HDAC activity is required during Xenopus tail regeneration. |
2011 |
PLoS ONE |
pmid:22022609
|
Rajak H et al. |
2,5-Disubstituted-1,3,4-oxadiazoles/thiadiazole as surface recognition moiety: design and synthesis of novel hydroxamic acid based histone deacetylase inhibitors. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21875796
|
He HM et al. |
[The effects of a histone deacetylase (HDAC) inhibitor on endotoxin-induced endothelial cell injury]. |
2011 |
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue |
pmid:22005560
|
Pichugin A et al. |
Ring-like distribution of constitutive heterochromatin in bovine senescent cells. |
2011 |
PLoS ONE |
pmid:22132080
|
Sanders YY et al. |
Epigenetic regulation of thy-1 by histone deacetylase inhibitor in rat lung fibroblasts. |
2011 |
Am. J. Respir. Cell Mol. Biol. |
pmid:20724553
|
Wang JP et al. |
Trichostatin A inhibits TGF-β1 induced in vitro chondrogenesis of hMSCs through Sp1 suppression. |
2011 |
Differentiation |
pmid:21074928
|
Oyer JA et al. |
Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation. |
2011 |
Mutat. Res. |
pmid:21035468
|
Pabba C et al. |
Design and synthesis of aryl ether and sulfone hydroxamic acids as potent histone deacetylase (HDAC) inhibitors. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21109435
|
Vrzal R et al. |
Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: a possible cause of valproic acid-induced osteomalacia? |
2011 |
Toxicol. Lett. |
pmid:21115105
|
Johansson AS et al. |
Valproic acid phase shifts the rhythmic expression of Period2::Luciferase. |
2011 |
J. Biol. Rhythms |
pmid:22215612
|
Zhou S et al. |
Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction. |
2011 |
Circ. Res. |
pmid:21778425
|
Yoo YE and Ko CP |
Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis. |
2011 |
Exp. Neurol. |
pmid:21712032
|
Sar P et al. |
3, 3'5 Triiodo L thyronine induces apoptosis in human breast cancer MCF-7 cells, repressing SMP30 expression through negative thyroid response elements. |
2011 |
PLoS ONE |
pmid:21687737
|
Cosner CC and Helquist P |
Concise, convergent syntheses of (±)-trichostatin A utilizing a Pd-catalyzed ketone enolate α-alkenylation reaction. |
2011 |
Org. Lett. |
pmid:21688856
|
Kojima S et al. |
Asymmetric leaves2 and Elongator, a histone acetyltransferase complex, mediate the establishment of polarity in leaves of Arabidopsis thaliana. |
2011 |
Plant Cell Physiol. |
pmid:21700721
|
Chik CL et al. |
Histone modifications on the adrenergic induction of type II deiodinase in rat pinealocytes. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21704117
|
Zhang L et al. |
ABA treatment of germinating maize seeds induces VP1 gene expression and selective promoter-associated histone acetylation. |
2011 |
Physiol Plant |
pmid:21679193
|
Lin S et al. |
HIV-1 reactivation induced by apicidin involves histone modification in latently infected cells. |
2011 |
Curr. HIV Res. |
pmid:21631428
|
Jugová A et al. |
Effects of epigenetic-based anti-cancer drugs in leukaemia and multiple myeloma cells. |
2011 |
Cell Biol. Int. |
pmid:21635225
|
Wong CY et al. |
Epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells. |
2011 |
J. Biol. Chem. |
pmid:21636851
|
Hayashi-Takanaka Y et al. |
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling. |
2011 |
Nucleic Acids Res. |
pmid:21576221
|
Bouquet F et al. |
A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia. |
2011 |
J. Cell. Sci. |
pmid:21576354
|
Hawk JD et al. |
Post-training intrahippocampal inhibition of class I histone deacetylases enhances long-term object-location memory. |
2011 |
Learn. Mem. |
pmid:21576516
|
Dong X et al. |
Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells. |
2011 |
Endocr. Relat. Cancer |
pmid:21367844
|
Zhu QY et al. |
C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo. |
2011 |
Cell Death Dis |
pmid:21368888
|
Hsu YF et al. |
p53 in trichostatin A induced C6 glioma cell death. |
2011 |
Biochim. Biophys. Acta |
pmid:21376104
|
Ryhänen T et al. |
Influence of Hsp90 and HDAC inhibition and tubulin acetylation on perinuclear protein aggregation in human retinal pigment epithelial cells. |
2011 |
J. Biomed. Biotechnol. |
pmid:20981255
|
Briggs B et al. |
Photosensitization by iodinated DNA minor groove binding ligands: Evaluation of DNA double-strand break induction and repair. |
2011 |
J. Photochem. Photobiol. B, Biol. |
pmid:21440453
|
Xiao J et al. |
Discovery, synthesis, and biological evaluation of novel SMN protein modulators. |
2011 |
J. Med. Chem. |
pmid:21819082
|
Patel T et al. |
Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice. |
2011 |
Immunol. Cell Biol. |
pmid:21321581
|
Shi G et al. |
The regulatory role of histone deacetylase inhibitors in Fgf4 expression is dependent on the differentiation state of pluripotent stem cells. |
2011 |
J. Cell. Physiol. |
pmid:21321941
|
Furuta K et al. |
The CKH2/PKL chromatin remodeling factor negatively regulates cytokinin responses in Arabidopsis calli. |
2011 |
Plant Cell Physiol. |
pmid:21357580
|
Fan Y et al. |
Derivation of cloned human blastocysts by histone deacetylase inhibitor treatment after somatic cell nuclear transfer with β-thalassemia fibroblasts. |
2011 |
Stem Cells Dev. |
pmid:21322785
|
Kim YJ et al. |
Comparison of potency between histone deacetylase inhibitors trichostatin A and valproic acid on enhancing in vitro development of porcine somatic cell nuclear transfer embryos. |
2011 |
In Vitro Cell. Dev. Biol. Anim. |
pmid:21359816
|
Jang ER et al. |
Different effect of protein kinase B/Akt and extracellular signal-regulated kinase inhibition on trichostatin A-induced apoptosis in epithelial ovarian carcinoma cell lines. |
2011 |
Mol. Cell. Biochem. |
pmid:21380726
|
Fan T et al. |
EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression. |
2011 |
Mol. Cancer Res. |
pmid:21383005
|
Yang J et al. |
[Study of RASSF1A expression and promoter demethylation in Hep-2 cell line]. |
2011 |
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi |
pmid:21473137
|
Cui XS et al. |
Trichostatin A modulates apoptotic-related gene expression and improves embryo viability in cloned bovine embryos. |
2011 |
Cell Reprogram |
pmid:21473694
|
Chen X et al. |
Design, synthesis and biological evaluation of hydroxamic acid derivatives as potential high density lipoprotein (HDL) receptor CLA-1 up-regulating agents. |
2011 |
Molecules |
pmid:22048700
|
Sun JY et al. |
Histone deacetylase inhibitors demonstrate significant preclinical activity as single agents, and in combination with bortezomib in Waldenström's macroglobulinemia. |
2011 |
Clin Lymphoma Myeloma Leuk |
pmid:21454220
|
Kong QR et al. |
[TSA improve transgenic porcine cloned embryo development and transgene expression]. |
2011 |
Yi Chuan |
pmid:22049689
|
Min XJ et al. |
Dysfunction of volume-sensitive chloride channels contributes to cisplatin resistance in human lung adenocarcinoma cells. |
2011 |
Exp. Biol. Med. (Maywood) |
pmid:21454376
|
Belakavadi M et al. |
Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21458529
|
Dávalos-Salas M et al. |
Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter. |
2011 |
BMC Cancer |
pmid:21663659
|
El-Serafi AT et al. |
Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A. |
2011 |
Differentiation |
pmid:20970916
|
Zelko IN et al. |
Histone acetylation regulates the cell-specific and interferon-γ-inducible expression of extracellular superoxide dismutase in human pulmonary arteries. |
2011 |
Am. J. Respir. Cell Mol. Biol. |
pmid:21493784
|
Zhang FQ et al. |
Cell-cycle-dependent variations in the FTIR spectroscopy of HeLa cells treated with trichostatin A. |
2011 |
Guang Pu Xue Yu Guang Pu Fen Xi |
pmid:22007388
|
da Costa Prando E et al. |
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines. |
2011 |
Epigenetics |
pmid:22139571
|
Nagamine MK et al. |
In vitro inhibitory effect of trichostatin A on canine grade 3 mast cell tumor. |
2011 |
Vet. Res. Commun. |
pmid:21472452
|
Kretzner L et al. |
Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels. |
2011 |
Cancer Res. |
pmid:21502403
|
Maruoka H et al. |
Low-molecular-weight compounds having neurotrophic activity in cultured PC12 cells and neurons. |
2011 |
J. Biochem. |
pmid:21908547
|
Poplineau M et al. |
Raman microspectroscopy detects epigenetic modifications in living Jurkat leukemic cells. |
2011 |
Epigenomics |
pmid:22126296
|
Qiu GH et al. |
Recognition and suppression of transfected plasmids by protein ZNF511-PRAP1, a potential molecular barrier to transgene expression. |
2011 |
Mol. Ther. |
pmid:21540836
|
Kong Q et al. |
Effect of trichostatin A and 5-Aza-2'-deoxycytidine on transgene reactivation and epigenetic modification in transgenic pig fibroblast cells. |
2011 |
Mol. Cell. Biochem. |
pmid:21541675
|
Wang QS et al. |
[Silence mechanism of WT1 gene in leukemic cell line U937]. |
2011 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:22040952
|
Park JW et al. |
Microbial transformation of trichostatin A to 2,3-dihydrotrichostatin A. |
2011 |
J. Nat. Prod. |
pmid:21504214
|
Matoba S et al. |
RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22065773
|
Bolleyn J et al. |
Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes. |
2011 |
Toxicol In Vitro |
pmid:21513791
|
Rajasingh J et al. |
Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells. |
2011 |
PLoS ONE |
pmid:21799893
|
Ramsey MR et al. |
Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma. |
2011 |
Cancer Res. |
pmid:21527555
|
Klawitter M et al. |
Human MMP28 expression is unresponsive to inflammatory stimuli and does not correlate to the grade of intervertebral disc degeneration. |
2011 |
J Negat Results Biomed |
pmid:21801383
|
Akagi S et al. |
Treatment with a histone deacetylase inhibitor after nuclear transfer improves the preimplantation development of cloned bovine embryos. |
2011 |
J. Reprod. Dev. |
pmid:20962457
|
Fu S et al. |
Involvement of histone acetylation of Sox17 and Foxa2 promoters during mouse definitive endoderm differentiation revealed by microRNA profiling. |
2011 |
PLoS ONE |
pmid:22132182
|
Mayor R et al. |
Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells. |
2011 |
Epigenetics |
pmid:21852760
|
Kumar A et al. |
γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines. |
2011 |
Int. J. Radiat. Biol. |
pmid:21815748
|
Tan L et al. |
Trichostatin A restores Apaf-1 function in chemoresistant ovarian cancer cells. |
2011 |
Cancer |
pmid:20925046
|
Jackson K et al. |
Epigenetic silencing of somatostatin in gastric cancer. |
2011 |
Dig. Dis. Sci. |
pmid:20927589
|
Sahu GK and Cloyd MW |
Latent HIV in primary T lymphocytes is unresponsive to histone deacetylase inhibitors. |
2011 |
Virol. J. |
pmid:21838863
|
Yu D et al. |
Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21840716
|
Atanackovic D et al. |
Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia. |
2011 |
Am. J. Hematol. |
pmid:21898529
|
Paterson S et al. |
Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells. |
2011 |
Drug Metab. Dispos. |
pmid:20870783
|
Wang JP et al. |
Recapitulation of fibromatosis nodule by multipotential stem cells in immunodeficient mice. |
2011 |
PLoS ONE |
pmid:21901157
|
Nakaya Y et al. |
Epigenetic regulation on the 5'-proximal CpG island of human porcine endogenous retrovirus subgroup A receptor 2/GPR172B. |
2011 |
Microbes Infect. |
pmid:20951222
|
Robers MB et al. |
Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology. |
2011 |
Mol Biosyst |
pmid:20931131
|
Hsu YF et al. |
MAPK phosphatase-1 contributes to trichostatin A inhibition of cyclooxygenase-2 expression in human umbilical vascular endothelial cells exposed to lipopolysaccharide. |
2011 |
Biochim. Biophys. Acta |
pmid:21911040
|
Crandall JE et al. |
Retinoic acid influences neuronal migration from the ganglionic eminence to the cerebral cortex. |
2011 |
J. Neurochem. |
pmid:21895658
|
Jafarpour F et al. |
Somatic cell-induced hyperacetylation, but not hypomethylation, positively and reversibly affects the efficiency of in vitro cloned blastocyst production in cattle. |
2011 |
Cell Reprogram |
pmid:21919704
|
Chen MY et al. |
Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy. |
2011 |
Cancer |
pmid:21491416
|
Ma AN et al. |
Histone deacetylation directs DNA methylation in survivin gene silencing. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21130077
|
Pianta A et al. |
Nucleophosmin delocalization in thyroid tumour cells. |
2011 |
Endocr. Pathol. |
pmid:21258971
|
Whitehead L et al. |
Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors. |
2011 |
Bioorg. Med. Chem. |
pmid:21723733
|
Yin H et al. |
Histonedeacetylase inhibitor Oxamflatin increase HIV-1 transcription by inducing histone modification in latently infected cells. |
2011 |
Mol. Biol. Rep. |
pmid:21181272
|
Stoppani E et al. |
Point mutated caveolin-3 form (P104L) impairs myoblast differentiation via Akt and p38 signalling reduction, leading to an immature cell signature. |
2011 |
Biochim. Biophys. Acta |
pmid:21182936
|
Puppin C et al. |
Histone deacetylase inhibitors control the transcription and alternative splicing of prohibitin in thyroid tumor cells. |
2011 |
Oncol. Rep. |
pmid:21152868
|
Tsai PF et al. |
Interplay between PKCδ and Sp1 on histone deacetylase inhibitor-mediated Epstein-Barr virus reactivation. |
2011 |
J. Virol. |
pmid:21159880
|
Nandakumar V et al. |
(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells. |
2011 |
Carcinogenesis |
pmid:21209038
|
Kang H and Roh S |
Extended exposure to trichostatin A after activation alters the expression of genes important for early development in nuclear transfer murine embryos. |
2011 |
J. Vet. Med. Sci. |
pmid:21187677
|
Mitmaker EJ et al. |
Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines using demethylating agents and histone deacetylase inhibitors. |
2011 |
Surgery |
pmid:21193210
|
Liao M et al. |
Coactivator function of positive cofactor 4 (PC4) in Sp1-directed luteinizing hormone receptor (LHR) gene transcription. |
2011 |
J. Biol. Chem. |
pmid:21193408
|
Erb TM et al. |
Paracrine and epigenetic control of trophectoderm differentiation from human embryonic stem cells: the role of bone morphogenic protein 4 and histone deacetylases. |
2011 |
Stem Cells Dev. |
pmid:21204619
|
Farinas B and Mas P |
Functional implication of the MYB transcription factor RVE8/LCL5 in the circadian control of histone acetylation. |
2011 |
Plant J. |
pmid:21205033
|
Host L et al. |
Cocaine self-administration alters the expression of chromatin-remodelling proteins; modulation by histone deacetylase inhibition. |
2011 |
J. Psychopharmacol. (Oxford) |
pmid:19939859
|
Muralidhar SA et al. |
Histone deacetylase 9 activates gamma-globin gene expression in primary erythroid cells. |
2011 |
J. Biol. Chem. |
pmid:21078662
|
Chakravarty G et al. |
Cytoplasmic compartmentalization of SOX9 abrogates the growth arrest response of breast cancer cells that can be rescued by trichostatin A treatment. |
2011 |
Cancer Biol. Ther. |
pmid:21084857
|