Chen Z et al. |
BCL11A represses HBG transcription in K562 cells. |
2009 Mar-Apr |
Blood Cells Mol. Dis. |
pmid:19153051
|
Wang L et al. |
Using histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance. |
2009 Mar-Apr |
Immunol. Cell Biol. |
pmid:19172156
|
Pollack BP et al. |
Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation. |
2009 May-Jun |
Photochem. Photobiol. |
pmid:19076306
|
Schuhmann NK et al. |
Gene transfer into human cord blood-derived CD34(+) cells by adeno-associated viral vectors. |
2010 |
Exp. Hematol. |
pmid:20447441
|
Zhang D et al. |
[Effects of trichostatin A on human lung cancer cell strains A549]. |
2010 |
Zhongguo Yi Xue Ke Xue Yuan Xue Bao |
pmid:20450546
|
Ju ZH et al. |
[Effects of 5-Aza-2'-deoxycitydine and trichostatin A on expression and apoptosis of ALDH1a2 gene in human bladder cancer cell lines]. |
2010 |
Zhonghua Wai Ke Za Zhi |
pmid:20450613
|
Urbinati G et al. |
Liposomes loaded with histone deacetylase inhibitors for breast cancer therapy. |
2010 |
Int J Pharm |
pmid:20603204
|
Sharma P et al. |
Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells. |
2010 |
Mol. Cancer |
pmid:20609221
|
Mizutani H et al. |
Romidepsin (FK228), a potent histone deacetylase inhibitor, induces apoptosis through the generation of hydrogen peroxide. |
2010 |
Cancer Sci. |
pmid:20624163
|
Yang J et al. |
A novel mechanism involving coordinated regulation of nuclear levels and acetylation of NF-YA and Bcl6 activates RGS4 transcription. |
2010 |
J. Biol. Chem. |
pmid:20630860
|
Wang XH et al. |
S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer. |
2010 |
Am. J. Pathol. |
pmid:20581057
|
Terhune SS et al. |
Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA. |
2010 |
PLoS Pathog. |
pmid:20585571
|
Luo W et al. |
Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer. |
2010 |
Cancer Res. |
pmid:20587525
|
Zaman MS et al. |
The functional significance of microRNA-145 in prostate cancer. |
2010 |
Br. J. Cancer |
pmid:20588276
|
Shu ST et al. |
Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells. |
2010 |
Anticancer Res. |
pmid:20651337
|
Paddock MN et al. |
The BRCT domain of PARP-1 is required for immunoglobulin gene conversion. |
2010 |
PLoS Biol. |
pmid:20652015
|
Mossman D et al. |
Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists. |
2010 |
BMC Cancer |
pmid:20618997
|
Ma J et al. |
Promoter hypermethylation and histone hypoacetylation contribute to pancreatic-duodenal homeobox 1 silencing in gastric cancer. |
2010 |
Carcinogenesis |
pmid:20622005
|
Oliveira CS et al. |
Effects of histone hyperacetylation on the preimplantation development of male and female bovine embryos. |
2010 |
Reprod. Fertil. Dev. |
pmid:20591338
|
Suo L et al. |
Changes in acetylation on lysine 12 of histone H4 (acH4K12) of murine oocytes during maternal aging may affect fertilization and subsequent embryo development. |
2010 |
Fertil. Steril. |
pmid:19285668
|
Xia J et al. |
Epigenetic modification of vomeronasal (V2r) precursor neurons by histone deacetylation. |
2010 |
Neuroscience |
pmid:20594945
|
Obier N and Müller AM |
Chromatin flow cytometry identifies changes in epigenetic cell states. |
2010 |
Cells Tissues Organs (Print) |
pmid:19776550
|
Fan J et al. |
Expression and function of CD9 in melanoma cells. |
2010 |
Mol. Carcinog. |
pmid:19777564
|
Tessema M et al. |
Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis. |
2010 |
Oncogene |
pmid:20562917
|
Kaimori A et al. |
Histone deacetylase inhibition suppresses the transforming growth factor beta1-induced epithelial-to-mesenchymal transition in hepatocytes. |
2010 |
Hepatology |
pmid:20564330
|
Dai X et al. |
Somatic nucleus reprogramming is significantly improved by m-carboxycinnamic acid bishydroxamide, a histone deacetylase inhibitor. |
2010 |
J. Biol. Chem. |
pmid:20566633
|
Sudo H and Baas PW |
Acetylation of microtubules influences their sensitivity to severing by katanin in neurons and fibroblasts. |
2010 |
J. Neurosci. |
pmid:20505088
|
Bui HT et al. |
Effect of trichostatin A on chromatin remodeling, histone modifications, DNA replication, and transcriptional activity in cloned mouse embryos. |
2010 |
Biol. Reprod. |
pmid:20505166
|
Kim IA et al. |
HDAC inhibitor-mediated radiosensitization in human carcinoma cells: a general phenomenon? |
2010 |
J. Radiat. Res. |
pmid:20505264
|
Chen J et al. |
Interplay of bromodomain and histone acetylation in the regulation of p300-dependent genes. |
2010 |
Epigenetics |
pmid:20505343
|
Liu YW et al. |
Inhibition of LPS-induced C/EBP delta by trichostatin A has a positive effect on LPS-induced cyclooxygenase 2 expression in RAW264.7 cells. |
2010 |
J. Cell. Biochem. |
pmid:20506344
|
Kitamoto S et al. |
Promoter hypomethylation contributes to the expression of MUC3A in cancer cells. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20510874
|
Liang Q et al. |
The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers. |
2010 |
Int. J. Cancer |
pmid:20112338
|
Beedanagari SR et al. |
Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines. |
2010 |
Toxicol. Lett. |
pmid:20116417
|
Lu Y et al. |
Trichostatin A, a histone deacetylase inhibitor, reduces lesion growth and hyperalgesia in experimentally induced endometriosis in mice. |
2010 |
Hum. Reprod. |
pmid:20118114
|
Hajji N et al. |
Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide. |
2010 |
Oncogene |
pmid:20118981
|
Das ZC et al. |
Lyophilized somatic cells direct embryonic development after whole cell intracytoplasmic injection into pig oocytes. |
2010 |
Cryobiology |
pmid:20691649
|
Heier CR et al. |
Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice. |
2010 |
Hum. Mol. Genet. |
pmid:20693262
|
Gay S et al. |
Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions. |
2010 |
EMBO Rep. |
pmid:20671737
|
Angst E et al. |
Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells. |
2010 |
Pancreas |
pmid:20173668
|
Zhang L et al. |
Histone deacetylase inhibitors attenuate acute lung injury during cecal ligation and puncture-induced polymicrobial sepsis. |
2010 |
World J Surg |
pmid:20177680
|
Wu Y et al. |
Constitutive and tumor necrosis factor-alpha-stimulated activation of nuclear factor-kappaB in immortalized endometriotic cells and their suppression by trichostatin A. |
2010 |
Gynecol. Obstet. Invest. |
pmid:20130413
|
Zhao J et al. |
Histone deacetylase inhibitors improve in vitro and in vivo developmental competence of somatic cell nuclear transfer porcine embryos. |
2010 |
Cell Reprogram |
pmid:20132015
|
Martinez-Diaz MA et al. |
Pre- and postimplantation development of swine-cloned embryos derived from fibroblasts and bone marrow cells after inhibition of histone deacetylases. |
2010 |
Cell Reprogram |
pmid:20132016
|
Host L et al. |
Inhibition of histone deacetylases in rats self-administering cocaine regulates lissencephaly gene-1 and reelin gene expression, as revealed by microarray technique. |
2010 |
J. Neurochem. |
pmid:20132486
|
Wu Y et al. |
Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. |
2010 |
BMC Cancer |
pmid:20132554
|
Aoyama M et al. |
Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways. |
2010 |
Nutrition |
pmid:20004081
|
Nunes MJ et al. |
Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription. |
2010 |
J. Neurochem. |
pmid:20096088
|
Aizawa S and Yamamuro Y |
Involvement of histone acetylation in the regulation of choline acetyltransferase gene in NG108-15 neuronal cells. |
2010 |
Neurochem. Int. |
pmid:20100532
|
Wu J et al. |
Trichostatin A sensitizes cisplatin-resistant A549 cells to apoptosis by up-regulating death-associated protein kinase. |
2010 |
Acta Pharmacol. Sin. |
pmid:20048748
|
Hebbel RP et al. |
The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice. |
2010 |
Blood |
pmid:20053759
|
He R et al. |
Synthesis and biological evaluation of triazol-4-ylphenyl-bearing histone deacetylase inhibitors as anticancer agents. |
2010 |
J. Med. Chem. |
pmid:20055418
|
Nicodeme E et al. |
Suppression of inflammation by a synthetic histone mimic. |
2010 |
Nature |
pmid:21068722
|
Ajiro K et al. |
Reciprocal epigenetic modification of histone H2B occurs in chromatin during apoptosis in vitro and in vivo. |
2010 |
Cell Death Differ. |
pmid:20057502
|
Auzzas L et al. |
Non-natural macrocyclic inhibitors of histone deacetylases: design, synthesis, and activity. |
2010 |
J. Med. Chem. |
pmid:21073160
|
Su Y et al. |
Human RecQL4 helicase plays critical roles in prostate carcinogenesis. |
2010 |
Cancer Res. |
pmid:21045146
|
Giles KE et al. |
Chromatin boundaries, insulators, and long-range interactions in the nucleus. |
2010 |
Cold Spring Harb. Symp. Quant. Biol. |
pmid:21047907
|
Bayles R et al. |
Histone modifications regulate the norepinephrine transporter gene. |
2010 |
Cell Cycle |
pmid:21088495
|
Li RJ et al. |
Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance. |
2010 |
Ann. Oncol. |
pmid:20038517
|
Nordén R et al. |
Inhibition of protein deacetylation augments herpes simplex virus type 1-activated transcription of host fucosyltransferase genes associated with virus-induced sLex expression. |
2010 |
Arch. Virol. |
pmid:20039087
|
Emonds E et al. |
Molecular determinants of the antitumor effects of trichostatin A in pancreatic cancer cells. |
2010 |
World J. Gastroenterol. |
pmid:20419833
|
Bao BY et al. |
Down-regulation of NF-kappaB signals is involved in loss of 1alpha,25-dihydroxyvitamin D3 responsiveness. |
2010 |
J. Steroid Biochem. Mol. Biol. |
pmid:20206692
|
Eskeland R et al. |
Histone acetylation and the maintenance of chromatin compaction by Polycomb repressive complexes. |
2010 |
Cold Spring Harb. Symp. Quant. Biol. |
pmid:21502416
|
Shiau RJ et al. |
Genistein and beta-carotene enhance the growth-inhibitory effect of trichostatin A in A549 cells. |
2010 |
Eur J Nutr |
pmid:19639378
|
Simboeck E et al. |
A phosphorylation switch regulates the transcriptional activation of cell cycle regulator p21 by histone deacetylase inhibitors. |
2010 |
J. Biol. Chem. |
pmid:20952396
|
Robertson DM et al. |
C-terminal cleavage of DeltaNp63alpha is associated with TSA-induced apoptosis in immortalized corneal epithelial cells. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
pmid:20375332
|
Halili MA et al. |
Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. |
2010 |
J. Leukoc. Biol. |
pmid:20200406
|
Karagiannis TC et al. |
Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes. |
2010 |
Aging (Albany NY) |
pmid:20930262
|
Reichrath S et al. |
Notch- and vitamin D signaling in 1,25(OH)2D3-resistant glioblastoma multiforme (GBM) cell lines. |
2010 |
J. Steroid Biochem. Mol. Biol. |
pmid:20206691
|
Milagre I et al. |
Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination. |
2010 |
J. Alzheimers Dis. |
pmid:20930312
|
Bertrand P |
Inside HDAC with HDAC inhibitors. |
2010 |
Eur J Med Chem |
pmid:20223566
|
Gao A et al. |
Methylation of PARP-1 promoter involved in the regulation of benzene-induced decrease of PARP-1 mRNA expression. |
2010 |
Toxicol. Lett. |
pmid:20230882
|
Majid S et al. |
Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer. |
2010 |
Cancer Res. |
pmid:20332239
|
Khobta A et al. |
Gene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region. |
2010 |
Nucleic Acids Res. |
pmid:20338881
|
Kim SH et al. |
Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein. |
2010 |
Breast Cancer Res. |
pmid:20388208
|
Kongruttanachok N et al. |
Replication independent DNA double-strand break retention may prevent genomic instability. |
2010 |
Mol. Cancer |
pmid:20356374
|
Terracciano S et al. |
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222. |
2010 |
Bioorg. Med. Chem. |
pmid:20381359
|
Zhang LX et al. |
Targeted deletion of NF-kappaB p50 diminishes the cardioprotection of histone deacetylase inhibition. |
2010 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:20382965
|
Pan L et al. |
HDAC4 inhibits the transcriptional activation of mda-7/IL-24 induced by Sp1. |
2010 |
Cell. Mol. Immunol. |
pmid:20383178
|
Kim HB et al. |
Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors. |
2010 |
Mol. Cell. Biol. |
pmid:20385772
|
Kitano A et al. |
Therapeutic potential of trichostatin A to control inflammatory and fibrogenic disorders of the ocular surface. |
2010 |
Mol. Vis. |
pmid:21203344
|
Sponziello M et al. |
Regulation of sodium/iodide symporter and lactoperoxidase expression in four human breast cancer cell lines. |
2010 |
J. Endocrinol. Invest. |
pmid:19794300
|
Himaki T et al. |
Effects of trichostatin A on in vitro development and transgene function in somatic cell nuclear transfer embryos derived from transgenic Clawn miniature pig cells. |
2010 |
Anim. Sci. J. |
pmid:20887307
|
Wu P et al. |
Ubiquitin B: an essential mediator of trichostatin A-induced tumor-selective killing in human cancer cells. |
2010 |
Cell Death Differ. |
pmid:19798105
|
Peidis P et al. |
HDAC pharmacological inhibition promotes cell death through the eIF2α kinases PKR and GCN2. |
2010 |
Aging (Albany NY) |
pmid:21076179
|
Di Renzo F et al. |
VPA-related axial skeletal defects and apoptosis: a proposed event cascade. |
2010 |
Reprod. Toxicol. |
pmid:19850124
|
Patil V et al. |
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group. |
2010 |
Bioorg. Med. Chem. |
pmid:19914074
|
Choi JH et al. |
TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:19914212
|
Dong G et al. |
Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells. |
2010 |
Am. J. Physiol. Renal Physiol. |
pmid:19889954
|
Bhuiyan MM et al. |
Production of Sei whale (Balaenoptera borealis) cloned embryos by inter- and intra-species somatic cell nuclear transfer. |
2010 |
J. Reprod. Dev. |
pmid:19893277
|
Ellis JK et al. |
Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes. |
2010 |
J. Proteome Res. |
pmid:19894772
|
Wang N and Tilly JL |
Epigenetic status determines germ cell meiotic commitment in embryonic and postnatal mammalian gonads. |
2010 |
Cell Cycle |
pmid:20009537
|
Law AY and Wong CK |
Stanniocalcin-2 is a HIF-1 target gene that promotes cell proliferation in hypoxia. |
2010 |
Exp. Cell Res. |
pmid:19786016
|
Estiu G et al. |
On the inhibition of histone deacetylase 8. |
2010 |
Bioorg. Med. Chem. |
pmid:20472442
|
Kobori A et al. |
Butyrate stimulates IL-32alpha expression in human intestinal epithelial cell lines. |
2010 |
World J. Gastroenterol. |
pmid:20480520
|
Kiyokawa S et al. |
New orally bioavailable 2-aminobenzamide-type histone deacetylase inhibitor possessing a (2-hydroxyethyl)(4-(thiophen-2-yl)benzyl)amino group. |
2010 |
Bioorg. Med. Chem. |
pmid:20452226
|
Barua S and Rege K |
The influence of mediators of intracellular trafficking on transgene expression efficacy of polymer-plasmid DNA complexes. |
2010 |
Biomaterials |
pmid:20452664
|
Marshall H et al. |
Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice. |
2010 |
BMC Mol. Biol. |
pmid:20429939
|
Zhao TC et al. |
gp-91 mediates histone deacetylase inhibition-induced cardioprotection. |
2010 |
Biochim. Biophys. Acta |
pmid:20433879
|
Jeon HW and Lee YM |
Inhibition of histone deacetylase attenuates hypoxia-induced migration and invasion of cancer cells via the restoration of RECK expression. |
2010 |
Mol. Cancer Ther. |
pmid:20442303
|