Kagoshima M et al. |
How signaling pathways interact with gene transcription. |
2003 Jan-Mar |
Monaldi Arch Chest Dis |
pmid:14533280
|
Kao HH et al. |
Genomic structure, gene expression, and promoter analysis of human multidrug resistance-associated protein 7. |
2003 Jan-Feb |
J. Biomed. Sci. |
pmid:12566991
|
Henderson C et al. |
Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA). |
2003 |
J. Biol. Chem. |
pmid:12556448
|
Palazzo A et al. |
Cell biology: Tubulin acetylation and cell motility. |
2003 |
Nature |
pmid:12529632
|
Fernandes I et al. |
Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms. |
2003 |
Mol. Cell |
pmid:12535528
|
Cheutin T et al. |
Maintenance of stable heterochromatin domains by dynamic HP1 binding. |
2003 |
Science |
pmid:12560555
|
Boutillier AL et al. |
Selective E2F-dependent gene transcription is controlled by histone deacetylase activity during neuronal apoptosis. |
2003 |
J. Neurochem. |
pmid:12562525
|
Tomita K et al. |
The effect of oxidative stress on histone acetylation and IL-8 release. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12565901
|
Kim Y et al. |
Decreased syndecan-2 expression correlates with trichostatin-A induced-morphological changes and reduced tumorigenic activity in colon carcinoma cells. |
2003 |
Oncogene |
pmid:12584561
|
Mishra N et al. |
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse. |
2003 |
J. Clin. Invest. |
pmid:12588892
|
Glaser KB et al. |
Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines. |
2003 |
Mol. Cancer Ther. |
pmid:12589032
|
Ailenberg M and Silverman M |
Differential effects of trichostatin A on gelatinase A expression in 3T3 fibroblasts and HT-1080 fibrosarcoma cells: implications for use of TSA in cancer therapy. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12604329
|
Sakai N et al. |
Involvement of histone acetylation in ovarian steroid-induced decidualization of human endometrial stromal cells. |
2003 |
J. Biol. Chem. |
pmid:12609987
|
Kim SY et al. |
Glial cell-specific regulation of the JC virus early promoter by histone deacetylase inhibitors. |
2003 |
J. Virol. |
pmid:12610114
|
Wang S and Zhu J |
Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter. |
2003 |
J. Biol. Chem. |
pmid:12611896
|
Shaker S et al. |
Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells. |
2003 |
Leuk. Res. |
pmid:12620295
|
Rahman MM et al. |
Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages. |
2003 |
Blood |
pmid:12511413
|
Musikacharoen T et al. |
Histone acetylation and activation of cAMP-response element-binding protein regulate transcriptional activation of MKP-M in lipopolysaccharide-stimulated macrophages. |
2003 |
J. Biol. Chem. |
pmid:12511574
|
Gusterson RJ et al. |
The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity. |
2003 |
J. Biol. Chem. |
pmid:12477714
|
Kondo Y et al. |
Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. |
2003 |
Mol. Cell. Biol. |
pmid:12482974
|
James SY et al. |
Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells. |
2003 |
Cancer Res. |
pmid:12839938
|
Ding Z et al. |
Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain. |
2003 |
Mol. Cell. Biol. |
pmid:12482978
|
Haggarty SJ et al. |
Small molecule modulation of the human chromatid decatenation checkpoint. |
2003 |
Chem. Biol. |
pmid:14700634
|
Kim DK et al. |
Synthesis and biological evaluation of 3-(4-substituted-phenyl)-N-hydroxy-2-propenamides, a new class of histone deacetylase inhibitors. |
2003 |
J. Med. Chem. |
pmid:14667227
|
Huang H et al. |
Expression of P53, P21 in human lung adenocarcinoma A549 cell strains under hypoxia conditions and the effect of TSA on their expression. |
2003 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:15015635
|
Obata T et al. |
Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer. |
2003 |
Clin. Cancer Res. |
pmid:14695142
|
Terui T et al. |
Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors. |
2003 |
Cancer Res. |
pmid:14695212
|
Liu A et al. |
Oligodendrocyte process outgrowth in vitro is modulated by epigenetic regulation of cytoskeletal severing proteins. |
2003 |
Glia |
pmid:14603467
|
Moreira JM et al. |
The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses. |
2003 |
BMC Cancer |
pmid:14606959
|
Remiszewski SW et al. |
N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824). |
2003 |
J. Med. Chem. |
pmid:14521422
|
Massillon D et al. |
Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. |
2003 |
J. Biol. Chem. |
pmid:12915406
|
Noh EJ and Lee JS |
Functional interplay between modulation of histone deacetylase activity and its regulatory role in G2-M transition. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14521905
|
Hong CY et al. |
Expression of MIS in the testis is downregulated by tumor necrosis factor alpha through the negative regulation of SF-1 transactivation by NF-kappa B. |
2003 |
Mol. Cell. Biol. |
pmid:12917325
|
Li C et al. |
Effect and comparison of sodium butyrate and trichostatin A on the proliferation/differentiation of K562. |
2003 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:14526425
|
Le Masson I et al. |
Yaf9, a novel NuA4 histone acetyltransferase subunit, is required for the cellular response to spindle stress in yeast. |
2003 |
Mol. Cell. Biol. |
pmid:12917332
|
Zhong S et al. |
Phosphorylation at serine 28 and acetylation at lysine 9 of histone H3 induced by trichostatin A. |
2003 |
Oncogene |
pmid:12917630
|
Condon JC et al. |
A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12886011
|
Ryu JR and Arnosti DN |
Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities. |
2003 |
Nucleic Acids Res. |
pmid:12888527
|
Pivot-Pajot C et al. |
Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. |
2003 |
Mol. Cell. Biol. |
pmid:12861021
|
Grassi G et al. |
Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87. |
2003 |
Carcinogenesis |
pmid:12869421
|
Ammanamanchi S et al. |
Acetylated sp3 is a transcriptional activator. |
2003 |
J. Biol. Chem. |
pmid:12837748
|
Krämer OH et al. |
The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2. |
2003 |
EMBO J. |
pmid:12840003
|
Tominaga K et al. |
MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner. |
2003 |
J. Biol. Chem. |
pmid:14506250
|
Kawai H et al. |
Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor alpha. |
2003 |
Int. J. Cancer |
pmid:14506733
|
Kishikawa S et al. |
Control elements of Dnmt1 gene are regulated in cell-cycle dependent manner. |
2003 |
Nucleic Acids Res. Suppl. |
pmid:14510503
|
Wegener D et al. |
Improved fluorogenic histone deacetylase assay for high-throughput-screening applications. |
2003 |
Anal. Biochem. |
pmid:14511685
|
Kim MS et al. |
Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. |
2003 |
Cancer Res. |
pmid:14612526
|
Miller TA et al. |
Histone deacetylase inhibitors. |
2003 |
J. Med. Chem. |
pmid:14613312
|
Hitomi T et al. |
p15(INK4b) in HDAC inhibitor-induced growth arrest. |
2003 |
FEBS Lett. |
pmid:14623092
|
Zhang Q et al. |
Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A. |
2003 |
Toxicol. Appl. Pharmacol. |
pmid:14575637
|
Usenko T et al. |
Transient expression of E1A and Ras oncogenes causes downregulation of c-fos gene transcription in nontransformed REF52 cells. |
2003 |
Oncogene |
pmid:14576829
|
Vasudevan A et al. |
Heterocyclic ketones as inhibitors of histone deacetylase. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:14592473
|
Chung YL et al. |
A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis. |
2003 |
Mol. Ther. |
pmid:14599803
|
Bhakat KK and Mitra S |
CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration. |
2003 |
Carcinogenesis |
pmid:12807730
|
Lu F et al. |
Chromatin remodeling of the Kaposi's sarcoma-associated herpesvirus ORF50 promoter correlates with reactivation from latency. |
2003 |
J. Virol. |
pmid:14557628
|
Lopatina NG et al. |
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12810068
|
Siddiqui H et al. |
Histone deacetylation of RB-responsive promoters: requisite for specific gene repression but dispensable for cell cycle inhibition. |
2003 |
Mol. Cell. Biol. |
pmid:14560017
|
Liu LT et al. |
Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. |
2003 |
Cancer Res. |
pmid:12810630
|
Shin HJ et al. |
Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation. |
2003 |
Oncogene |
pmid:12813458
|
Kim TY et al. |
Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells. |
2003 |
Oncogene |
pmid:12813468
|
Kim JM et al. |
Changes in histone acetylation during mouse oocyte meiosis. |
2003 |
J. Cell Biol. |
pmid:12835313
|
Camarero N et al. |
Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site. |
2003 |
Nucleic Acids Res. |
pmid:12626711
|
Park KK et al. |
Modulation of Sp1-dependent transcription by a cis-acting E2F element in dhfr promoter. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12788094
|
Marks J et al. |
Two functionally divergent p53-responsive elements in the rat bradykinin B2 receptor promoter. |
2003 |
J. Biol. Chem. |
pmid:12791684
|
Valls E et al. |
The SV40 T antigen modulates CBP histone acetyltransferase activity. |
2003 |
Nucleic Acids Res. |
pmid:12799439
|
Ferguson M et al. |
Histone deacetylase inhibition is associated with transcriptional repression of the Hmga2 gene. |
2003 |
Nucleic Acids Res. |
pmid:12799440
|
Ji Y et al. |
A multistep mechanism for the activation of rearrangement in the immune system. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12802019
|
Nemajerová A et al. |
Trichostatin A suppresses transformation by the v-myb oncogene in BM2 cells. |
2003 |
J. Hematother. Stem Cell Res. |
pmid:12804181
|
Park PH et al. |
Acetylation of histone H3 at lysine 9 by ethanol in rat hepatocytes. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12804592
|
Kim H et al. |
The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12816733
|
Shteper PJ et al. |
Role of promoter methylation in regulation of the mammalian heparanase gene. |
2003 |
Oncogene |
pmid:14586400
|
Klan N et al. |
Trichostatin A and structurally related histone deacetylase inhibitors induce 5-lipoxygenase promoter activity. |
2003 |
Biol. Chem. |
pmid:12817474
|
Hirose T et al. |
p53-independent induction of Gadd45 by histone deacetylase inhibitor: coordinate regulation by transcription factors Oct-1 and NF-Y. |
2003 |
Oncogene |
pmid:14586402
|
Yamada Y et al. |
Aberrant methylation of the vascular endothelial growth factor receptor-1 gene in prostate cancer. |
2003 |
Cancer Sci. |
pmid:12824880
|
Shi W et al. |
Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos. |
2003 |
Biol. Reprod. |
pmid:12646489
|
Murumägi A et al. |
Characterization of regulatory elements and methylation pattern of the autoimmune regulator (AIRE) promoter. |
2003 |
J. Biol. Chem. |
pmid:12651856
|
Kang J et al. |
Nickel-induced histone hypoacetylation: the role of reactive oxygen species. |
2003 |
Toxicol. Sci. |
pmid:12773760
|
Kim EJ et al. |
Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML. |
2003 |
Nucleic Acids Res. |
pmid:12954772
|
Brugarolas JB et al. |
TSC2 regulates VEGF through mTOR-dependent and -independent pathways. |
2003 |
Cancer Cell |
pmid:12957289
|
Cimini D et al. |
Histone hyperacetylation in mitosis prevents sister chromatid separation and produces chromosome segregation defects. |
2003 |
Mol. Biol. Cell |
pmid:12972566
|
Schuettengruber B et al. |
Autoregulation of mouse histone deacetylase 1 expression. |
2003 |
Mol. Cell. Biol. |
pmid:12972616
|
Yang Y et al. |
The histone code regulating expression of the imprinted mouse Igf2r gene. |
2003 |
Endocrinology |
pmid:12975326
|
Hu E et al. |
Identification of novel isoform-selective inhibitors within class I histone deacetylases. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12975486
|
Craig JM et al. |
Centromeric chromatin pliability and memory at a human neocentromere. |
2003 |
EMBO J. |
pmid:12743043
|
Enright BP et al. |
Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2'-deoxycytidine. |
2003 |
Biol. Reprod. |
pmid:12748129
|
Van Ommeslaeghe K et al. |
Amide analogues of TSA: synthesis, binding mode analysis and HDAC inhibition. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12749885
|
Zhao S et al. |
Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor beta Type II receptor expression in human pancreatic cancer cells. |
2003 |
Cancer Res. |
pmid:12750289
|
Schauber J et al. |
Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. |
2003 |
Gut |
pmid:12692061
|
Rambhatla L et al. |
Generation of hepatocyte-like cells from human embryonic stem cells. |
2003 |
Cell Transplant |
pmid:12693659
|
Lee SC et al. |
Activation of terminal B cell differentiation by inhibition of histone deacetylation. |
2003 |
Mol. Immunol. |
pmid:12695118
|
Chandler SP et al. |
Fragile X (CGG)n repeats induce a transcriptional repression in cis upon a linked promoter: evidence for a chromatin mediated effect. |
2003 |
BMC Mol. Biol. |
pmid:12659659
|
Zika E et al. |
Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation. |
2003 |
Mol. Cell. Biol. |
pmid:12697811
|
Mihaylova VT et al. |
Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. |
2003 |
Mol. Cell. Biol. |
pmid:12697826
|
Kao GD et al. |
Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. |
2003 |
J. Cell Biol. |
pmid:12668657
|
Yasui W et al. |
Histone acetylation and gastrointestinal carcinogenesis. |
2003 |
Ann. N. Y. Acad. Sci. |
pmid:12724227
|
Jedrusik MA and Schulze E |
Telomeric position effect variegation in Saccharomyces cerevisiae by Caenorhabditis elegans linker histones suggests a mechanistic connection between germ line and telomeric silencing. |
2003 |
Mol. Cell. Biol. |
pmid:12724425
|
Jang IC et al. |
Structure and expression of the rice class-I type histone deacetylase genes OsHDAC1-3: OsHDAC1 overexpression in transgenic plants leads to increased growth rate and altered architecture. |
2003 |
Plant J. |
pmid:12581311
|
Bouchain G et al. |
Development of potential antitumor agents. Synthesis and biological evaluation of a new set of sulfonamide derivatives as histone deacetylase inhibitors. |
2003 |
J. Med. Chem. |
pmid:12593661
|
Castro-Galache MD et al. |
Susceptibility of multidrug resistance tumor cells to apoptosis induction by histone deacetylase inhibitors. |
2003 |
Int. J. Cancer |
pmid:12594812
|
Teyssier C et al. |
Receptor-interacting protein 140 binds c-Jun and inhibits estradiol-induced activator protein-1 activity by reversing glucocorticoid receptor-interacting protein 1 effect. |
2003 |
Mol. Endocrinol. |
pmid:12554755
|