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Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. |
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Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures. |
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Haematologica |
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DNA methylation regulates placental lactogen I gene expression. |
2001 |
Endocrinology |
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Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. |
2001 |
Endocrinology |
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Trichostatin A inhibits beta-casein expression in mammary epithelial cells. |
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Trichostatin A, an inhibitor of histone deacetylase, inhibits hypoxia-induced angiogenesis. |
2001 |
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Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
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Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. |
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Reactivation of feline foamy virus from a chronically infected feline renal cell line by trichostatin A. |
2001 |
Virology |
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Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells. |
2001 |
Thyroid |
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Induction of histone acetylation in mouse erythroleukemia cells by some organosulfur compounds including allyl isothiocyanate. |
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Int. J. Cancer |
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The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. |
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EMBO J. |
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Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. |
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Oncogene |
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Increased transcription levels induce higher mutation rates in a hypermutating cell line. |
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Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells. |
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Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells. |
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Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development. |
2001 |
Zygote |
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Genes modulated by histone acetylation as new effectors of butyrate activity. |
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FEBS Lett. |
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Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. |
2001 |
Science |
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A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. |
2001 |
Genetics |
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3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. |
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Evidence for gene silencing in Haemophilus influenzae. |
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Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. |
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Cancer Res. |
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Telomere position effect in human cells. |
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Science |
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Multipathways for transdifferentiation of human prostate cancer cells into neuroendocrine-like phenotype. |
2001 |
Biochim. Biophys. Acta |
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Position effects are influenced by the orientation of a transgene with respect to flanking chromatin. |
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A hematopoietic-specific transmembrane protein, Art-1, is possibly regulated by AML1. |
2001 |
Biochem. Biophys. Res. Commun. |
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Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter. |
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Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation. |
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Mol. Cell. Biol. |
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Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice. |
2001 |
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Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
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Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. |
2001 |
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Mechanisms involved in the homologous down-regulation of transcription of the follicle-stimulating hormone receptor gene in Sertoli cells. |
2001 |
Mol. Cell. Endocrinol. |
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Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. |
2001 |
Mol. Cell. Biol. |
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The CpG island promoter of the human proopiomelanocortin gene is methylated in nonexpressing normal tissue and tumors and represses expression. |
2001 |
Mol. Endocrinol. |
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Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma. |
2001 |
Carcinogenesis |
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Inhibition of histone deacetylation induces constitutive derepression of the beta interferon promoter and confers antiviral activity. |
2001 |
J. Virol. |
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The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. |
2001 |
Mol. Cell. Biol. |
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Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator. |
2001 |
J. Virol. |
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Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. |
2001 |
Biochem. Biophys. Res. Commun. |
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Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain. |
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FEBS Lett. |
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Cell type-specific roles of histone deacetylase in TR ligand-independent transcriptional repression. |
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Mol. Cell. Endocrinol. |
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Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity. |
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DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. |
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Cancer Res. |
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Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription. |
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EMBO J. |
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Loss of PU.1 expression following inhibition of histone deacetylases. |
2001 |
J. Immunol. |
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Chemical agents that promote chromatin compaction radiosensitize tumour cells. |
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