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Bsr, a nuclear-retained RNA with monoallelic expression. |
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Mol. Biol. Cell |
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Histone deacetylase as therapeutic target in a rodent model of hemorrhagic shock: effect of different resuscitation strategies on lung and liver. |
2007 |
Surgery |
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ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate. |
2007 |
Biochem. Biophys. Res. Commun. |
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Changes in histone acetylation during postovulatory aging of mouse oocyte. |
2007 |
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Design, synthesis, and evaluation of isoindolinone-hydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors. |
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Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. |
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Prostaglandin F2alpha inhibits adipocyte differentiation via a G alpha q-calcium-calcineurin-dependent signaling pathway. |
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Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells. |
2007 |
Leukemia |
pmid:17625602
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Bu Y and Gelman IH |
v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex. |
2007 |
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Steroids and histone deacetylase in ventilation-induced gene transcription. |
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2007 |
Am. J. Physiol., Cell Physiol. |
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The combination of the histone-deacetylase inhibitor trichostatin A and gemcitabine induces inhibition of proliferation and increased apoptosis in pancreatic carcinoma cells. |
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Epigenetic regulation of CD20 protein expression in a novel B-cell lymphoma cell line, RRBL1, established from a patient treated repeatedly with rituximab-containing chemotherapy. |
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Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica. |
2007 |
BMC Genomics |
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Haploinsufficient prostate tumor suppression by Nkx3.1: a role for chromatin accessibility in dosage-sensitive gene regulation. |
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Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis. |
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Arthritis Rheum. |
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Differentiation of eosinophilic leukemia EoL-1 cells into eosinophils induced by histone deacetylase inhibitors. |
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Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity. |
2007 |
Neuron |
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Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma. |
2007 |
Neuro-oncology |
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Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression. |
2007 |
Cancer |
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Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. |
2007 |
Blood |
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Differential regulation of thrombospondin-1 expression and antiangiogenesis of ECV304 cells by trichostatin A and helixor A. |
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Anticancer Drugs |
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Insulin-like Growth Factor Binding Protein-3 expression in the human corneal epithelium. |
2007 |
Exp. Eye Res. |
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Histone deacetylase inhibitors reduce steroidogenesis through SCF-mediated ubiquitination and degradation of steroidogenic factor 1 (NR5A1). |
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Am. J. Physiol. Lung Cell Mol. Physiol. |
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Expression of GAGE family proteins in malignant melanoma. |
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Dev. Cell |
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HDAC inhibitors TSA and sodium butyrate enhanced the human IL-5 expression by altering histone acetylation status at its promoter region. |
2007 |
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Cancer Sci. |
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The histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes. |
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Biochim. Biophys. Acta |
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2007 |
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Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor. |
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Mol. Cancer |
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PLoS Genet. |
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Reproduction |
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Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression. |
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Biochim. Biophys. Acta |
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High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma. |
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Mol. Cancer Res. |
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Activities of maturation-promoting factor (MPF) and mitogen-activated protein kinase (MAPK) are not required for the global histone deacetylation observed after germinal vesicle breakdown (GVBD) in porcine oocytes. |
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Reproduction |
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Effect of downregulation of survivin expression on radiosensitivity of human epidermoid carcinoma cells. |
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Int. J. Radiat. Oncol. Biol. Phys. |
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NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. |
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Mixtures of SCFA, composed according to physiologically available concentrations in the gut lumen, modulate histone acetylation in human HT29 colon cancer cells. |
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Dev. Biol. |
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Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes. |
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Mol. Cell. Probes |
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2006 |
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Mol. Biol. Cell |
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Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells. |
2006 |
Endocr. Relat. Cancer |
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TSA-induced cell death in prostate cancer cell lines is caspase-2 dependent and involves the PIDDosome. |
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Cancer Biol. Ther. |
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Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia. |
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Neurochem. Int. |
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Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. |
2006 |
FASEB J. |
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Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
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Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. |
2006 |
Biol. Chem. |
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Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. |
2006 |
Arthritis Rheum. |
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Trichostatin A cooperates with Fas-mediated signal to induce apoptosis in rheumatoid arthritis synovial fibroblasts. |
2006 |
J. Rheumatol. |
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Involvement of caspase activation and mitochondrial stress in trichostatin A-induced apoptosis of Burkitt's lymphoma cell line, Akata. |
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RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. |
2006 |
Cancer Res. |
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Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. |
2006 |
Cancer Res. |
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Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. |
2006 |
Mol. Biol. Cell |
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HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers. |
2006 |
Exp. Cell Res. |
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Qi H and Ratnam M |
Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. |
2006 |
Cancer Res. |
pmid:16740727
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Nusinzon I and Horvath CM |
Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation. |
2006 |
Mol. Cell. Biol. |
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Identification of novel target genes by an epigenetic reactivation screen of renal cancer. |
2006 |
Cancer Res. |
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Histone deacetylase inhibitors suppress the inducibility of nuclear factor-kappaB by tumor necrosis factor-alpha receptor-1 down-regulation. |
2006 |
Cancer Res. |
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Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors. |
2006 |
Virol. J. |
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E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer. |
2006 |
Oncogene |
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Kim MY et al. |
Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. |
2006 |
Mol. Endocrinol. |
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Leng Y and Chuang DM |
Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. |
2006 |
J. Neurosci. |
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LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression. |
2006 |
FASEB J. |
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Clem BF and Clark BJ |
Association of the mSin3A-histone deacetylase 1/2 corepressor complex with the mouse steroidogenic acute regulatory protein gene. |
2006 |
Mol. Endocrinol. |
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Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. |
2006 |
Arterioscler. Thromb. Vasc. Biol. |
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Inhibitors of histone deacetylases and DNA methyltransferases alter imprinted gene regulation in embryonic stem cells. |
2006 |
Cloning Stem Cells |
pmid:17009896
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[Mechanism of apoptosis induced by trichostatin A in leukemia Molt-4 cells analyzed by microarray]. |
2006 |
Ai Zheng |
pmid:16965673
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Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. |
2006 |
Clin. Cancer Res. |
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Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. |
2006 |
J. Med. Chem. |
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Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. |
2006 |
Cancer Res. |
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Alteration of developmental program in Paramecium by treatment with trichostatin a: a possible involvement of histone modification. |
2006 |
Protist |
pmid:16839811
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Monte M et al. |
MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16847267
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Zaveri NT et al. |
Regulation of the prepronociceptin gene and its effect on neuronal differentiation. |
2006 |
Gene |
pmid:16935438
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Dokras A et al. |
Epigenetic regulation of maspin expression in the human placenta. |
2006 |
Mol. Hum. Reprod. |
pmid:16936308
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Yamamura K et al. |
Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis. |
2006 |
Br. J. Haematol. |
pmid:16939493
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Baraz L et al. |
Tumor suppressor p53 regulates heparanase gene expression. |
2006 |
Oncogene |
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Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. |
2006 |
Nucleic Acids Res. |
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