Huang W et al. |
Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex. |
2005 |
J. Biol. Chem. |
pmid:15647279
|
Place RF et al. |
HDACs and the senescent phenotype of WI-38 cells. |
2005 |
BMC Cell Biol. |
pmid:16250917
|
Lee JH et al. |
Interactions with p300 enhance transcriptional activation by the PDZ-domain coactivator Bridge-1. |
2005 |
J. Endocrinol. |
pmid:16293776
|
Hazzalin CA and Mahadevan LC |
Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: analysis at c-fos and c-jun. |
2005 |
PLoS Biol. |
pmid:16262446
|
Lin KT et al. |
Epigenetic activation of alpha4, beta2 and beta6 integrins involved in cell migration in trichostatin A-treated Hep3B cells. |
2005 |
J. Biomed. Sci. |
pmid:16132114
|
Smardová J et al. |
CBP sensitizes v-myb-transformed monoblasts to differentiation inducers. |
2005 |
Differentiation |
pmid:16026544
|
Fandy TE et al. |
Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma. |
2005 |
Neoplasia |
pmid:16026644
|
Korutla L et al. |
The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal-like cultures. |
2005 |
J. Neurochem. |
pmid:16033423
|
Shindo N et al. |
The ESC-E(Z) complex participates in the hedgehog signaling pathway. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15652519
|
Galfi P et al. |
Divergent effects of resveratrol, a polyphenolic phytostilbene, on free radical levels and type of cell death induced by the histone deacetylase inhibitors butyrate and trichostatin A. |
2005 |
J. Steroid Biochem. Mol. Biol. |
pmid:15862948
|
Choi KH et al. |
Activation of CMV promoter-controlled glycosyltransferase and beta -galactosidase glycogenes by butyrate, tricostatin A, and 5-aza-2'-deoxycytidine. |
2005 |
Glycoconj. J. |
pmid:15864436
|
Wooten LG and Ogretmen B |
Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide. |
2005 |
J. Biol. Chem. |
pmid:15951564
|
Malago JJ et al. |
Anti-inflammatory properties of heat shock protein 70 and butyrate on Salmonella-induced interleukin-8 secretion in enterocyte-like Caco-2 cells. |
2005 |
Clin. Exp. Immunol. |
pmid:15958071
|
Whang YM et al. |
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells. |
2005 |
Cancer Chemother. Pharmacol. |
pmid:15959780
|
Gunin AG et al. |
Effects of histone deacetylase inhibitors on estradiol-induced proliferation and hyperplasia formation in the mouse uterus. |
2005 |
J. Endocrinol. |
pmid:15930180
|
Wittich S et al. |
Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines. |
2005 |
Anticancer Drugs |
pmid:15930892
|
Fishel ML et al. |
Effect of cell cycle inhibition on Cisplatin-induced cytotoxicity. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15304523
|
Wagner S and Roemer K |
Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf. |
2005 |
Biochem. Pharmacol. |
pmid:15763542
|
Kawamura T et al. |
Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes. |
2005 |
J. Biol. Chem. |
pmid:15764815
|
Xiong Y et al. |
Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells. |
2005 |
Cancer Res. |
pmid:15805266
|
Kumakura S et al. |
Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells. |
2005 |
Cancer Res. |
pmid:15805278
|
Fujisawa K et al. |
Epigenetic status and aberrant expression of the maspin gene in human hepato-biliary tract carcinomas. |
2005 |
Lab. Invest. |
pmid:15608662
|
Bottardi S et al. |
Onset and inheritance of abnormal epigenetic regulation in hematopoietic cells. |
2005 |
Hum. Mol. Genet. |
pmid:15615768
|
Ezzat S et al. |
The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility. |
2005 |
Mol. Endocrinol. |
pmid:15618287
|
Kawano T et al. |
Depsipeptide enhances imatinib mesylate-induced apoptosis of Bcr-Abl-positive cells and ectopic expression of cyclin D1, c-Myc or active MEK abrogates this effect. |
2004 Sep-Oct |
Anticancer Res. |
pmid:15517875
|
Fenic I et al. |
In vivo effects of histone-deacetylase inhibitor trichostatin-A on murine spermatogenesis. |
2004 Sep-Oct |
J. Androl. |
pmid:15292114
|
Emionite L et al. |
Histone deacetylase inhibitors enhance retinoid response in human breast cancer cell lines. |
2004 Nov-Dec |
Anticancer Res. |
pmid:15736447
|
Karasawa Y and Okisaka S |
Inhibition of histone deacetylation by butyrate induces morphological changes in Y79 retinoblastoma cells. |
2004 Nov-Dec |
Jpn. J. Ophthalmol. |
pmid:15592778
|
Flørenes VA et al. |
Deacetylase inhibition in malignant melanomas: impact on cell cycle regulation and survival. |
2004 |
Melanoma Res. |
pmid:15179185
|
Ahn MR et al. |
Trichostatin A, a histone deacetylase inhibitor stimulate CYP3A4 proximal promoter activity in Hepa-I cells. |
2004 |
Arch. Pharm. Res. |
pmid:15180307
|
Vanhaecke T et al. |
Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view. |
2004 |
Curr. Med. Chem. |
pmid:15180568
|
Kato N et al. |
Regulation of Chk2 gene expression in lymphoid malignancies: involvement of epigenetic mechanisms in Hodgkin's lymphoma cell lines. |
2004 |
Cell Death Differ. |
pmid:15153943
|
Ramakrishnan G et al. |
Histone acetyltransferases and deacetylase in Entamoeba histolytica. |
2004 |
Mol. Biochem. Parasitol. |
pmid:15555732
|
Zoumpoulidou G et al. |
Convergence of interferon-gamma and progesterone signaling pathways in human endometrium: role of PIASy (protein inhibitor of activated signal transducer and activator of transcription-y). |
2004 |
Mol. Endocrinol. |
pmid:15155784
|
Wang LG et al. |
Androgen receptor level controlled by a suppressor complex lost in an androgen-independent prostate cancer cell line. |
2004 |
Oncogene |
pmid:15156193
|
Romanski A et al. |
Use of a novel histone deacetylase inhibitor to induce apoptosis in cell lines of acute lymphoblastic leukemia. |
2004 |
Haematologica |
pmid:15075075
|
Bayart E et al. |
A major role for mitotic CDC2 kinase inactivation in the establishment of the mitotic DNA damage checkpoint. |
2004 |
Cancer Res. |
pmid:15604258
|
Ahmed S et al. |
A novel protein with similarities to Rb binding protein 2 compensates for loss of Chk1 function and affects histone modification in fission yeast. |
2004 |
Mol. Cell. Biol. |
pmid:15082762
|
Amor DJ et al. |
Human centromere repositioning "in progress". |
2004 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:15084747
|
Tani M et al. |
Correlation between histone acetylation and expression of the MYO18B gene in human lung cancer cells. |
2004 |
Genes Chromosomes Cancer |
pmid:15101048
|
Lasa A et al. |
MEIS 1 expression is downregulated through promoter hypermethylation in AML1-ETO acute myeloid leukemias. |
2004 |
Leukemia |
pmid:15103390
|
Yokota T et al. |
Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter. |
2004 |
Oncogene |
pmid:15107822
|
Chang HC et al. |
Involvement of histone deacetylation in ras-induced down-regulation of the metastasis suppressor RECK. |
2004 |
Cell. Signal. |
pmid:15093608
|
Nishino N et al. |
Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15109626
|
Marson CM et al. |
Stereodefined and polyunsaturated inhibitors of histone deacetylase based on (2E,4E)-5-arylpenta-2,4-dienoic acid hydroxyamides. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15109636
|
Arapshian A et al. |
Epigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancer. |
2004 |
Mol. Cancer |
pmid:15113415
|
Mizukami T et al. |
Effects of trichostatin a, a histone deacetylase inhibitor, on mouse gonadal development in vitro. |
2004 |
J. Reprod. Dev. |
pmid:15118250
|
Ganslmayer M et al. |
A quadruple therapy synergistically blocks proliferation and promotes apoptosis of hepatoma cells. |
2004 |
Oncol. Rep. |
pmid:15069530
|
Margueron R et al. |
Histone deacetylase inhibition and estrogen receptor alpha levels modulate the transcriptional activity of partial antiestrogens. |
2004 |
J. Mol. Endocrinol. |
pmid:15072561
|
Reifenberger J et al. |
Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas. |
2004 |
Int. J. Cancer |
pmid:14961576
|
Sugimoto S et al. |
Expression and regulation of tumor suppressor gene maspin in human bladder cancer. |
2004 |
Cancer Lett. |
pmid:14732229
|
Vaisburg A et al. |
(2-amino-phenyl)-amides of omega-substituted alkanoic acids as new histone deacetylase inhibitors. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:14684344
|
Lu XC et al. |
[Effect of inhibitors for demethylation and histone deacetylase on proliferation of cell line K562 and expression of tumor related genes]. |
2004 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:14989767
|
Nojima H et al. |
Increase in DNA methylation downregulates conceptus interferon-tau gene expression. |
2004 |
Mol. Reprod. Dev. |
pmid:14991730
|
Leu TH et al. |
Participation of p97Eps8 in Src-mediated transformation. |
2004 |
J. Biol. Chem. |
pmid:14699156
|
Chua YL et al. |
Microarray analysis of chromatin-immunoprecipitated DNA identifies specific regions of tobacco genes associated with acetylated histones. |
2004 |
Plant J. |
pmid:14996214
|
Khan AN et al. |
An epigenetically altered tumor cell vaccine. |
2004 |
Cancer Immunol. Immunother. |
pmid:14997346
|
Pagans S et al. |
Repression by TTK69 of GAGA-mediated activation occurs in the absence of TTK69 binding to DNA and solely requires the contribution of the POZ/BTB domain of TTK69. |
2004 |
J. Biol. Chem. |
pmid:14701830
|
Ragno R et al. |
3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies. |
2004 |
J. Med. Chem. |
pmid:14998325
|
Hwang CK et al. |
Transcriptional regulation of mouse mu opioid receptor gene by PU.1. |
2004 |
J. Biol. Chem. |
pmid:14998994
|
Gray SG et al. |
Microarray profiling of the effects of histone deacetylase inhibitors on gene expression in cancer cell lines. |
2004 |
Int. J. Oncol. |
pmid:15010814
|
Aapola U et al. |
Epigenetic modifications affect Dnmt3L expression. |
2004 |
Biochem. J. |
pmid:15015937
|
Burton GR et al. |
Microarray analysis of differentiation-specific gene expression during 3T3-L1 adipogenesis. |
2004 |
Gene |
pmid:15033539
|
Elaut G et al. |
Rat hepatocyte suspensions as a suitable in vitro model for studying the biotransformation of histone deacetylase inhibitors. |
2004 |
Altern Lab Anim |
pmid:23577441
|
Ladd PD et al. |
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus. |
2004 |
Gene |
pmid:15474314
|
Li H and Wu X |
Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15474507
|
Spenger A et al. |
Influence of promoter choice and trichostatin A treatment on expression of baculovirus delivered genes in mammalian cells. |
2004 |
Protein Expr. Purif. |
pmid:15477077
|
Yee SB et al. |
Trichostatin A induces apoptosis of p815 mastocytoma cells in histone acetylation- and mitochondria-dependent fashion. |
2004 |
Int. J. Oncol. |
pmid:15492835
|
Young JC et al. |
Inhibitors of histone deacetylases promote hematopoietic stem cell self-renewal. |
2004 |
Cytotherapy |
pmid:16146885
|
Um SJ et al. |
In vitro antitumor potential of 4-BPRE, a butyryl aminophenyl ester of retinoic acid: role of the butyryl group. |
2004 |
Oncol. Rep. |
pmid:14767528
|
Fan X et al. |
Regulation of RANKL promoter activity is associated with histone remodeling in murine bone stromal cells. |
2004 |
J. Cell. Biochem. |
pmid:15389882
|
Chen YX et al. |
Histone acetylation regulates p21WAF1 expression in human colon cancer cell lines. |
2004 |
World J. Gastroenterol. |
pmid:15309711
|
Heltweg B et al. |
Subtype selective substrates for histone deacetylases. |
2004 |
J. Med. Chem. |
pmid:15456267
|
Alikhani-Koopaei R et al. |
Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. |
2004 |
J. Clin. Invest. |
pmid:15489962
|
Marsili G et al. |
Role of acetylases and deacetylase inhibitors in IRF-1-mediated HIV-1 long terminal repeat transcription. |
2004 |
Ann. N. Y. Acad. Sci. |
pmid:15659847
|
Keen JC et al. |
Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells. |
2004 |
Cancer Biol. Ther. |
pmid:15662126
|
Jang ER et al. |
The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor alpha-negative breast cancer cells to tamoxifen. |
2004 |
Oncogene |
pmid:14676837
|
Thelen P et al. |
Expressional changes after histone deacetylase inhibition by valproic acid in LNCaP human prostate cancer cells. |
2004 |
Int. J. Oncol. |
pmid:14654937
|
Kramps C et al. |
E2F and Sp1/Sp3 Synergize but are not sufficient to activate the MYCN gene in neuroblastomas. |
2004 |
J. Biol. Chem. |
pmid:14645238
|
Chaturvedi V et al. |
Resistance to UV-induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53. |
2004 |
J. Cell. Physiol. |
pmid:14584049
|
Laeng P et al. |
The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cells. |
2004 |
J. Neurochem. |
pmid:15379904
|
Gaudier E et al. |
Butyrate specifically modulates MUC gene expression in intestinal epithelial goblet cells deprived of glucose. |
2004 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:15308471
|
Schultz BE et al. |
Kinetics and comparative reactivity of human class I and class IIb histone deacetylases. |
2004 |
Biochemistry |
pmid:15323567
|
Tao D et al. |
Trichostatin A extends the lifespan of Drosophila melanogaster by elevating hsp22 expression. |
2004 |
Acta Biochim. Biophys. Sin. (Shanghai) |
pmid:15346199
|
Korkmaz CG et al. |
Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation--rescue of transcriptionally compromised mutants. |
2004 |
J. Endocrinol. |
pmid:15350180
|
Akimoto T |
[Potentiation of radiation-induced cell killing by histone deacetylase inhibitor]. |
2004 |
Nippon Rinsho |
pmid:15283155
|
Joung KE et al. |
Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells. |
2004 |
Arch. Pharm. Res. |
pmid:15283467
|
Kang J et al. |
Synergistic killing of human leukemia cells by antioxidants and trichostatin A. |
2004 |
Cancer Chemother. Pharmacol. |
pmid:15248029
|
Jin B and Ryu DY |
Regulation of CYP1A2 by histone deacetylase inhibitors in mouse hepatocytes. |
2004 |
J. Biochem. Mol. Toxicol. |
pmid:15252868
|
Gilchrist S et al. |
Nuclear organization of centromeric domains is not perturbed by inhibition of histone deacetylases. |
2004 |
Chromosome Res. |
pmid:15254368
|
Aggarwal BD and Calvi BR |
Chromatin regulates origin activity in Drosophila follicle cells. |
2004 |
Nature |
pmid:15254542
|
Sanderson L et al. |
Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice. |
2004 |
Drug Metab. Dispos. |
pmid:15269190
|
Levenson JM et al. |
Regulation of histone acetylation during memory formation in the hippocampus. |
2004 |
J. Biol. Chem. |
pmid:15273246
|
Li X et al. |
Regulation of histone acetylation and apoptosis by trichostatin in HL-60 cells. |
2004 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:15791844
|
Liu C and Xu D |
Inhibition of histone deacetylases. |
2004 |
Methods Mol. Biol. |
pmid:15273406
|
Garfinkel MD et al. |
Multigenerational selection and detection of altered histone acetylation and methylation patterns: toward a quantitative epigenetics in Drosophila. |
2004 |
Methods Mol. Biol. |
pmid:15273410
|
Vanhaecke T et al. |
Effect of the histone deacetylase inhibitor trichostatin A on spontaneous apoptosis in various types of adult rat hepatocyte cultures. |
2004 |
Biochem. Pharmacol. |
pmid:15276083
|
ChuÄkin IA et al. |
[Transcription of c-fos gene and DNA binding activity of transcription factor AP-1 increase upon differentiation of mouse F9 teratocarcinoma cells]. |
2004 |
Tsitologiia |
pmid:15747838
|
Sumer H et al. |
Effects of scaffold/matrix alteration on centromeric function and gene expression. |
2004 |
J. Biol. Chem. |
pmid:15220334
|
Lee YJ et al. |
Mechanism of transcriptional repression by TEL/RUNX1 fusion protein. |
2004 |
Mol. Cells |
pmid:15179033
|