Vilar E et al. |
Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. |
2009 |
Clin. Cancer Res. |
pmid:19351759
|
Lu SC et al. |
The essential role of Oct-2 in LPS-induced expression of iNOS in RAW 264.7 macrophages and its regulation by trichostatin A. |
2009 |
Am. J. Physiol., Cell Physiol. |
pmid:19279235
|
Diplas AI et al. |
Demonstration of all-or-none loss of imprinting in mRNA expression in single cells. |
2009 |
Nucleic Acids Res. |
pmid:19767614
|
Ma XX et al. |
Histone deacetylase inhibitor trichostatin A modulates cell cycles in A2780 human ovarian cancer cell lines. |
2009 |
Eur. J. Gynaecol. Oncol. |
pmid:19697617
|
Wiesen JL and Tomasi TB |
Dicer is regulated by cellular stresses and interferons. |
2009 |
Mol. Immunol. |
pmid:19118902
|
Togi S et al. |
HDAC3 influences phosphorylation of STAT3 at serine 727 by interacting with PP2A. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19121623
|
Woodfield GW et al. |
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. |
2009 |
Clin. Cancer Res. |
pmid:19458056
|
Hauswald S et al. |
Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes. |
2009 |
Clin. Cancer Res. |
pmid:19458058
|
Rahim R and Strobl JS |
Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells. |
2009 |
Anticancer Drugs |
pmid:19584707
|
Nadasi E et al. |
Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells. |
2009 |
Anticancer Res. |
pmid:19528494
|
Charrier C et al. |
Synthesis and modeling of new benzofuranone histone deacetylase inhibitors that stimulate tumor suppressor gene expression. |
2009 |
J. Med. Chem. |
pmid:19385600
|
Yap OW et al. |
Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells. |
2009 |
Anticancer Res. |
pmid:19331143
|
Popova EY et al. |
Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. |
2009 |
Chromosome Res. |
pmid:19172406
|
Lee JH et al. |
Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway. |
2009 |
Mol. Cancer Res. |
pmid:19808903
|
Susick L et al. |
Regulatory roles for histone deacetylation in IL-1beta-induced nitric oxide release in pancreatic beta-cells. |
2008 Sep-Oct |
J. Cell. Mol. Med. |
pmid:18053091
|
Li X and Bai XZ |
[NF-kappaB modulates activation of the BMP-2 gene by trichostatin A]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
pmid:19140318
|
Kir'ianov GI et al. |
[Nucleosome positioning within neomycinphosphotransferase gene (NPTII) on yeast plasmid in repressed and active state]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
pmid:19140324
|
Miyoshi M et al. |
Short-chain fatty acids and trichostatin A alter tight junction permeability in human umbilical vein endothelial cells. |
2008 Nov-Dec |
Nutrition |
pmid:18723323
|
Nishikiori N et al. |
Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9. |
2008 May-Jun |
Jpn. J. Ophthalmol. |
pmid:18661270
|
Fenic I et al. |
In vivo application of histone deacetylase inhibitor trichostatin-a impairs murine male meiosis. |
2008 Mar-Apr |
J. Androl. |
pmid:18046049
|
Smetana K et al. |
To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A. |
2008 Jul-Sep |
Eur J Histochem |
pmid:18840553
|
Kovács P and Csaba G |
The effect of histone deacetylase inhibitor trichostatin A (TSA) on the incorporation of 32P (Pi) and 3H-palmitic acid into the phospholipids of Tetrahymena. |
2008 Jan-Feb |
Cell Biochem. Funct. |
pmid:17191269
|
Dowling DP et al. |
Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. |
2008 |
Biochemistry |
pmid:19053282
|
Ishii T et al. |
[Epigenetic regulation in alcohol-related brain damage]. |
2008 |
Nihon Arukoru Yakubutsu Igakkai Zasshi |
pmid:19068777
|
Gray SG et al. |
Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells. |
2008 |
Clin Lung Cancer |
pmid:19073520
|
Zhu K et al. |
Telomerase expression and cell proliferation in ovarian cancer cells induced by histone deacetylase inhibitors. |
2008 |
Arch. Gynecol. Obstet. |
pmid:17680259
|
Nair S et al. |
Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells. |
2008 |
Pharm. Res. |
pmid:17657594
|
Zhou Q et al. |
Histone deacetylase inhibitors blocked activation and caused senescence of corneal stromal cells. |
2008 |
Mol. Vis. |
pmid:19122829
|
Meng CF et al. |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP]. |
2008 |
Ai Zheng |
pmid:19079988
|
Usami M et al. |
Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. |
2008 |
Nutr Res |
pmid:19083427
|
Krämer OH et al. |
Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis. |
2008 |
Oncogene |
pmid:17653085
|
Tanaka M et al. |
The Arabidopsis histone deacetylases HDA6 and HDA19 contribute to the repression of embryonic properties after germination. |
2008 |
Plant Physiol. |
pmid:18024558
|
Arany I et al. |
Restoration of CREB function ameliorates cisplatin cytotoxicity in renal tubular cells. |
2008 |
Am. J. Physiol. Renal Physiol. |
pmid:18094030
|
Jiemjit A et al. |
p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. |
2008 |
Oncogene |
pmid:18223691
|
Nasu Y et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model. |
2008 |
Osteoarthr. Cartil. |
pmid:18226559
|
Lim HG et al. |
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro. |
2008 |
Mol. Ther. |
pmid:18227841
|
Ruau D et al. |
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. |
2008 |
Stem Cells |
pmid:18203677
|
Serrano E et al. |
Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias. |
2008 |
Leuk. Res. |
pmid:18206229
|
Hamner JB et al. |
The efficacy of combination therapy using adeno-associated virus--interferon beta and trichostatin A in vitro and in a murine model of neuroblastoma. |
2008 |
J. Pediatr. Surg. |
pmid:18206478
|
Duhamel M et al. |
Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells. |
2008 |
FEBS Lett. |
pmid:18206652
|
Joseph RA et al. |
Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking. |
2008 |
Hepatology |
pmid:18161881
|
Shi LH et al. |
Trichostatin A and nuclear reprogramming of cloned rabbit embryos. |
2008 |
J. Anim. Sci. |
pmid:18245503
|
Paris M et al. |
Histone deacetylase inhibitors: from bench to clinic. |
2008 |
J. Med. Chem. |
pmid:18247554
|
Byers J and Eichinger D |
Acetylation of the Entamoeba histone H4 N-terminal domain is influenced by short-chain fatty acids that enter trophozoites in a pH-dependent manner. |
2008 |
Int. J. Parasitol. |
pmid:17706222
|
Campanero MR et al. |
The histone deacetylase inhibitor trichostatin A induces GADD45 gamma expression via Oct and NF-Y binding sites. |
2008 |
Oncogene |
pmid:17724474
|
Manning J et al. |
Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours. |
2008 |
Immunology |
pmid:17725605
|
Pan J et al. |
TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells. |
2008 |
Mol. Cancer Res. |
pmid:18505930
|
Hou J et al. |
Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and its relationship with DNA methylation. |
2008 |
BMC Dev. Biol. |
pmid:18507869
|
Dalgard CL et al. |
Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma. |
2008 |
Clin. Cancer Res. |
pmid:18483379
|
Oliva J et al. |
Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. |
2008 |
Exp. Mol. Pathol. |
pmid:18280469
|
Nakamura C et al. |
Anti-arthritic effects of combined treatment with histone deacetylase inhibitor and low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells. |
2008 |
Rheumatology (Oxford) |
pmid:18281366
|
Yu WP et al. |
Induction of ID1 expression and apoptosis by the histone deacetylase inhibitor (trichostatin A) in human acute myeloid leukaemic cells. |
2008 |
Cell Prolif. |
pmid:18211287
|
Kikuno N et al. |
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. |
2008 |
Int. J. Cancer |
pmid:18431742
|
van West P et al. |
Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. |
2008 |
Microbiology (Reading, Engl.) |
pmid:18451057
|
Zhang HJ et al. |
Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease. |
2008 |
Placenta |
pmid:18440631
|
Liu Z et al. |
Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. |
2008 |
Oncol. Rep. |
pmid:18575731
|
Meja KK et al. |
Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. |
2008 |
Am. J. Respir. Cell Mol. Biol. |
pmid:18421014
|
Plouffe D et al. |
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18579783
|
Sebastián C et al. |
Deacetylase activity is required for STAT5-dependent GM-CSF functional activity in macrophages and differentiation to dendritic cells. |
2008 |
J. Immunol. |
pmid:18424709
|
Sun Y et al. |
Modulation of transcription parameters in glucocorticoid receptor-mediated repression. |
2008 |
Mol. Cell. Endocrinol. |
pmid:18583028
|
Tshuikina M et al. |
Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma. |
2008 |
Exp. Hematol. |
pmid:18922617
|
Biacsi R et al. |
SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome. |
2008 |
PLoS Genet. |
pmid:18369442
|
Hishikawa K and Fujita T |
[Kidney regeneration update]. |
2008 |
Nippon Rinsho |
pmid:18464514
|
Wu X et al. |
Trichostatin A improved epigenetic modifications of transfected cells but did not improve subsequent cloned embryo development. |
2008 |
Anim. Biotechnol. |
pmid:18855246
|
Lindström TM et al. |
Histone deacetylase inhibitors exert time-dependent effects on nuclear factor-kappaB but consistently suppress the expression of proinflammatory genes in human myometrial cells. |
2008 |
Mol. Pharmacol. |
pmid:18375836
|
Kato A et al. |
Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions. |
2008 |
Exp. Cell Res. |
pmid:18588874
|
Li J et al. |
High in vitro development after somatic cell nuclear transfer and trichostatin A treatment of reconstructed porcine embryos. |
2008 |
Theriogenology |
pmid:18573521
|
Xu ZM et al. |
The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage. |
2008 |
BMB Rep |
pmid:18377727
|
Chen CJ et al. |
Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18590721
|
Karantzali E et al. |
Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis. |
2008 |
Genome Biol. |
pmid:18394158
|
Marengo E et al. |
Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies. |
2008 |
J. Proteome Res. |
pmid:18543959
|
Galiová G et al. |
Chromatin changes induced by lamin A/C deficiency and the histone deacetylase inhibitor trichostatin A. |
2008 |
Eur. J. Cell Biol. |
pmid:18396346
|
Zhu X et al. |
Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells. |
2008 |
J. Clin. Endocrinol. Metab. |
pmid:18544619
|
Gaviraghi M et al. |
Identification of a candidate alternative promoter region of the human Bcl2L11 (Bim) gene. |
2008 |
BMC Mol. Biol. |
pmid:18549468
|
Mühlethaler-Mottet A et al. |
Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells. |
2008 |
Mol. Cancer |
pmid:18549473
|
Kim B et al. |
Clinically relevant concentrations of valproic acid modulate melatonin MT(1) receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells. |
2008 |
Eur. J. Pharmacol. |
pmid:18550052
|
Tavera-Mendoza LE et al. |
Incorporation of histone deacetylase inhibition into the structure of a nuclear receptor agonist. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18550844
|
Lee TB et al. |
Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy. |
2008 |
BMC Gastroenterol |
pmid:18673531
|
Liu TC et al. |
Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. |
2008 |
Mol. Ther. |
pmid:18388912
|
Pluemsampant S et al. |
Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors. |
2008 |
Int. J. Cancer |
pmid:17935135
|
Law AY et al. |
Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. |
2008 |
Exp. Cell Res. |
pmid:18652825
|
Bosisio D et al. |
Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. |
2008 |
J. Leukoc. Biol. |
pmid:18780875
|
Yang L et al. |
[Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. |
2008 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:18718068
|
Zou XM et al. |
Gastric cancer cell lines induced by trichostatin A. |
2008 |
World J. Gastroenterol. |
pmid:18720545
|
Nishino N et al. |
Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides. |
2008 |
Bioorg. Med. Chem. |
pmid:17900911
|
Duan H et al. |
Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells. |
2008 |
Oncogene |
pmid:18695675
|
Ding X et al. |
Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A. |
2008 |
Theriogenology |
pmid:18556056
|
Jia J and Chen J |
Histone hyperacetylation is involved in the quercetin-induced human leukemia cell death. |
2008 |
Pharmazie |
pmid:18557424
|
Narver HL et al. |
Sustained improvement of spinal muscular atrophy mice treated with trichostatin A plus nutrition. |
2008 |
Ann. Neurol. |
pmid:18661558
|
Yu J et al. |
Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. |
2008 |
Hepatology |
pmid:18666234
|
Iacobazzi V et al. |
Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18706393
|
Liu F et al. |
Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin. |
2008 |
J. Mol. Cell. Cardiol. |
pmid:18926829
|
Gu Z et al. |
Promoter hypermethylation is not the major mechanism for inactivation of the FBXW7 beta-form in human gliomas. |
2008 |
Genes Genet. Syst. |
pmid:18931460
|
Yoshioka H et al. |
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. |
2008 |
J. Biol. Chem. |
pmid:18801729
|
Wu Y and Guo SW |
Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells. |
2008 |
Eur. J. Obstet. Gynecol. Reprod. Biol. |
pmid:17376583
|
Han JQ et al. |
[Effects of trichostatin A on the interaction between HBx and histone deacetylase protein 1]. |
2008 |
Zhonghua Gan Zang Bing Za Zhi |
pmid:18822204
|
Lee EJ et al. |
Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. |
2008 |
Int. J. Oncol. |
pmid:18813790
|
Van Wagoner DR and Nattel S |
Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy. |
2008 |
J. Mol. Cell. Cardiol. |
pmid:18817781
|
Pellicciotta I et al. |
Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition. |
2008 |
Cancer Res. |
pmid:18829567
|
Hitchler MJ et al. |
Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells. |
2008 |
Free Radic. Biol. Med. |
pmid:18845242
|