Wallace DM and Cotter TG |
Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661W cells and the retina. |
2009 |
J. Neurosci. Res. |
pmid:18951482
|
Li M et al. |
Upregulation of human with-no-lysine kinase-4 gene expression by GATA-1 acetylation. |
2009 |
Int. J. Biochem. Cell Biol. |
pmid:18793746
|
Patel V et al. |
Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum. |
2009 |
J. Med. Chem. |
pmid:19317450
|
GarcÃa-Villegas R et al. |
Identification and functional characterization of the promoter of the mouse sodium-activated sodium channel Na(x) gene (Scn7a). |
2009 |
J. Neurosci. Res. |
pmid:19326446
|
Seo J et al. |
Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19289100
|
Cecconi D et al. |
Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. |
2009 |
Proteomics |
pmid:19294695
|
Ikeda S et al. |
Enhancement of histone acetylation by trichostatin A during in vitro fertilization of bovine oocytes affects cell number of the inner cell mass of the resulting blastocysts. |
2009 |
Zygote |
pmid:19356267
|
Morita K et al. |
Histone deacetylase inhibitors promote neurosteroid-mediated cell differentiation and enhance serotonin-stimulated brain-derived neurotrophic factor gene expression in rat C6 glioma cells. |
2009 |
J. Neurosci. Res. |
pmid:19360904
|
von Burstin J et al. |
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. |
2009 |
Gastroenterology |
pmid:19362090
|
Yang X et al. |
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. |
2009 |
PLoS ONE |
pmid:19340297
|
Slattery EL et al. |
Epigenetic influences on sensory regeneration: histone deacetylases regulate supporting cell proliferation in the avian utricle. |
2009 |
J. Assoc. Res. Otolaryngol. |
pmid:19340485
|
Beebe LF et al. |
Cytochalasin B and trichostatin a treatment postactivation improves in vitro development of porcine somatic cell nuclear transfer embryos. |
2009 |
Cloning Stem Cells |
pmid:19780698
|
Olsen CA and Ghadiri MR |
Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic alpha3beta-tetrapeptides. |
2009 |
J. Med. Chem. |
pmid:19705846
|
Kee HJ and Kook H |
Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy. |
2009 |
J. Mol. Cell. Cardiol. |
pmid:19729022
|
Ong DC et al. |
LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer. |
2009 |
Oncogene |
pmid:19734946
|
Alao JP et al. |
Inhibition of type I histone deacetylase increases resistance of checkpoint-deficient cells to genotoxic agents through mitotic delay. |
2009 |
Mol. Cancer Ther. |
pmid:19723888
|
Bennett KL et al. |
AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma. |
2009 |
PLoS ONE |
pmid:19742317
|
Meng CF et al. |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells]. |
2009 |
Zhonghua Wei Chang Wai Ke Za Zhi |
pmid:19742343
|
Dombrowsky H et al. |
Conserved responses to trichostatin A in rodent lungs exposed to endotoxin or stretch. |
2009 |
Pulm Pharmacol Ther |
pmid:19744573
|
Dandrea M et al. |
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines. |
2009 |
Nucleic Acids Res. |
pmid:19745053
|
Lugrin J et al. |
Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation. |
2009 |
Biochim. Biophys. Acta |
pmid:19747950
|
Cervera RP et al. |
Trichostatin A affects histone acetylation and gene expression in porcine somatic cell nucleus transfer embryos. |
2009 |
Theriogenology |
pmid:19765811
|
Chen FQ et al. |
Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea. |
2009 |
J. Neurochem. |
pmid:19141081
|
Zhao W et al. |
Histone deacetylase inhibitor, trichostatin A, affects gene expression patterns during morphogenesis of chicken limb buds in vivo. |
2009 |
Cells Tissues Organs (Print) |
pmid:19147985
|
Giustiniani J et al. |
Tubulin acetylation favors Hsp90 recruitment to microtubules and stimulates the signaling function of the Hsp90 clients Akt/PKB and p53. |
2009 |
Cell. Signal. |
pmid:19136058
|
Chen Y et al. |
3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment. |
2009 |
Eur J Med Chem |
pmid:19136179
|
Cowell RM et al. |
Identification of novel targets for PGC-1alpha and histone deacetylase inhibitors in neuroblastoma cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19118529
|
Sutcliffe EL et al. |
Dynamic histone variant exchange accompanies gene induction in T cells. |
2009 |
Mol. Cell. Biol. |
pmid:19158270
|
Bagui TK et al. |
Inhibition of p27Kip1 gene transcription by mitogens. |
2009 |
Cell Cycle |
pmid:19158484
|
Wang X et al. |
Inhibition of histone deacetylases antagonized FGF2 and IL-1beta effects on MMP expression in human articular chondrocytes. |
2009 |
Growth Factors |
pmid:19107653
|
Cao Y et al. |
Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19966229
|
Trunzer M et al. |
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation. |
2009 |
J. Med. Chem. |
pmid:19108654
|
Smil DV et al. |
Novel HDAC6 isoform selective chiral small molecule histone deacetylase inhibitors. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19111466
|
Azzi A et al. |
Schistosoma mansoni: developmental arrest of miracidia treated with histone deacetylase inhibitors. |
2009 |
Exp. Parasitol. |
pmid:19094990
|
Hambach L et al. |
Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. |
2009 |
Blood |
pmid:19096014
|
Mavis CK et al. |
Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors. |
2009 |
Prostate |
pmid:19444856
|
Samuni Y et al. |
The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation. |
2009 |
Free Radic. Biol. Med. |
pmid:19447172
|
Gavin DP et al. |
Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. |
2009 |
J Psychiatry Neurosci |
pmid:19448855
|
Astrand C et al. |
Histone acetylation characterizes chromatin presetting by NF1 and Oct1 and enhances glucocorticoid receptor binding to the MMTV promoter. |
2009 |
Exp. Cell Res. |
pmid:19463811
|
Riester D et al. |
Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19457659
|
Gan YH and Zhang S |
PTEN/AKT pathway involved in histone deacetylases inhibitor induced cell growth inhibition and apoptosis of oral squamous cell carcinoma cells. |
2009 |
Oral Oncol. |
pmid:19574087
|
Wang XX and Fu L |
[Recent advances in DNA demethylation in tumor therapy]. |
2009 |
Zhonghua Bing Li Xue Za Zhi |
pmid:19575888
|
Soriano FX et al. |
Role of histone acetylation in the activity-dependent regulation of sulfiredoxin and sestrin 2. |
2009 |
Epigenetics |
pmid:19430206
|
Sawarkar R et al. |
Histone deacetylases regulate multicellular development in the social amoeba Dictyostelium discoideum. |
2009 |
J. Mol. Biol. |
pmid:19576222
|
Hsu PY et al. |
Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells. |
2009 |
Cancer Res. |
pmid:19549897
|
Noh H et al. |
Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury. |
2009 |
Am. J. Physiol. Renal Physiol. |
pmid:19553350
|
Jonsen MD et al. |
The 26-amino acid beta-motif of the Pit-1beta transcription factor is a dominant and independent repressor domain. |
2009 |
Mol. Endocrinol. |
pmid:19556346
|
Link PA et al. |
Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells. |
2009 |
Mol. Cancer Res. |
pmid:19531572
|
Chen IH et al. |
Cytotoxic triterpenoids from the stems of Microtropis japonica. |
2009 |
J. Nat. Prod. |
pmid:19534471
|
Casero RA and Woster PM |
Recent advances in the development of polyamine analogues as antitumor agents. |
2009 |
J. Med. Chem. |
pmid:19534534
|
Dubois F et al. |
Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni. |
2009 |
Mol. Biochem. Parasitol. |
pmid:19538992
|
Ma XL et al. |
[Construction of anti-sense cDNA library of human breast cancer cells during apoptosis induced by trichostatin A and preliminary screening of essential genes]. |
2009 |
Zhonghua Yi Xue Za Zhi |
pmid:19567099
|
Moon C et al. |
Use of epigenetic modification to induce FOXP3 expression in naïve T cells. |
2009 |
Transplant. Proc. |
pmid:19545742
|
Thiel A et al. |
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. |
2009 |
Clin. Cancer Res. |
pmid:19584167
|
Kim SN et al. |
Regulation of adipocyte differentiation by histone deacetylase inhibitors. |
2009 |
Arch. Pharm. Res. |
pmid:19407971
|
Hirose N et al. |
ATF-2 regulates lipopolysaccharide-induced transcription in macrophage cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19422799
|
Park SJ et al. |
Trichostatin A sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by down-regulation of c-FLIPL via inhibition of EGFR pathway. |
2009 |
Biochem. Pharmacol. |
pmid:19426671
|
Piotrowska H and Jagodzinski PP |
Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells. |
2009 |
Arch. Med. Res. |
pmid:19427965
|
López-Soto A et al. |
HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: potential implications for the immunosurveillance of cancer. |
2009 |
Oncogene |
pmid:19430493
|
Kim W et al. |
Histone acetyltransferase GCN5 interferes with the miRNA pathway in Arabidopsis. |
2009 |
Cell Res. |
pmid:19436261
|
Yoshida M |
Chemical genomics: a key to the epigenome - an interview with Minoru Yoshida. Interview by Saadi Khochbin. |
2009 |
Int. J. Dev. Biol. |
pmid:19412886
|
Han DW et al. |
Epigenetic hierarchy governing Nestin expression. |
2009 |
Stem Cells |
pmid:19415779
|
Derks S et al. |
Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. |
2009 |
Carcinogenesis |
pmid:19329758
|
Liu X et al. |
The improvement of adenovirus vector production by increased expression of coxsackie adenovirus receptor. |
2009 |
Biotechnol. Lett. |
pmid:19330491
|
Hollosi P et al. |
Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells. |
2009 |
Int. J. Cancer |
pmid:19330836
|
Chen J et al. |
E1A has no effect on LPS-induced IL-6 secretion in rat alveolar epithelial cells. |
2009 |
Respiration |
pmid:19299891
|
Yeh JR et al. |
Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. |
2009 |
Nat. Chem. Biol. |
pmid:19172146
|
Shao GB et al. |
Effect of trychostatin A treatment on gene expression in cloned mouse embryos. |
2009 |
Theriogenology |
pmid:19246084
|
Cunneen TS et al. |
In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells. |
2009 |
Arch. Ophthalmol. |
pmid:19365017
|
Åuczak MW and JagodziÅ„ski PP |
Trichostatin A down-regulates CYP19 transcript and protein levels in MCF-7 breast cancer cells. |
2009 |
Biomed. Pharmacother. |
pmid:18602794
|
Kusakabe M et al. |
Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19878646
|
Ma X et al. |
Identification of LIV1, a putative zinc transporter gene responsible for HDACi-induced apoptosis, using a functional gene screen approach. |
2009 |
Mol. Cancer Ther. |
pmid:19887557
|
Puca R et al. |
HIPK2 modulates p53 activity towards pro-apoptotic transcription. |
2009 |
Mol. Cancer |
pmid:19828042
|
Röhrs S et al. |
Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia. |
2009 |
Mol. Cancer |
pmid:19835597
|
Wang Y et al. |
HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. |
2009 |
Neurosci. Lett. |
pmid:19835929
|
Mastitskaya S and Denecke B |
Human spongiosa mesenchymal stem cells fail to generate cardiomyocytes in vitro. |
2009 |
J Negat Results Biomed |
pmid:19903342
|
Kawamura T et al. |
Inhibitory effects of short-chain fatty acids on matrix metalloproteinase secretion from human colonic subepithelial myofibroblasts. |
2009 |
Dig. Dis. Sci. |
pmid:18629644
|
Auer D et al. |
Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. |
2009 |
Breast Cancer Res. Treat. |
pmid:18618240
|
Kakihana M et al. |
Induction of E-cadherin in lung cancer and interaction with growth suppression by histone deacetylase inhibition. |
2009 |
J Thorac Oncol |
pmid:20009910
|
O'Leary DA et al. |
Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening. |
2009 |
PLoS ONE |
pmid:20020055
|
Halaban R et al. |
Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. |
2009 |
PLoS ONE |
pmid:19234609
|
Maalouf WE et al. |
Trichostatin A treatment of cloned mouse embryos improves constitutive heterochromatin remodeling as well as developmental potential to term. |
2009 |
BMC Dev. Biol. |
pmid:19210795
|
Sakurai T et al. |
Induction of endogenous interferon tau gene transcription by CDX2 and high acetylation in bovine nontrophoblast cells. |
2009 |
Biol. Reprod. |
pmid:19211809
|
Chakravorty M et al. |
IL1B promoter polymorphism regulates the expression of gastric acid stimulating hormone gastrin. |
2009 |
Int. J. Biochem. Cell Biol. |
pmid:19166966
|
Zhang D et al. |
[Synergistic cytotoxicity effect of histone deacetylase inhibitor combined with paclitaxel on lung cancer cell lines and its mechanism]. |
2009 |
Ai Zheng |
pmid:19958621
|
Lu MC et al. |
Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A. |
2009 |
Arch. Toxicol. |
pmid:18709356
|
Sharma A et al. |
Trichostatin a inhibits corneal haze in vitro and in vivo. |
2009 |
Invest. Ophthalmol. Vis. Sci. |
pmid:19168895
|
Li X et al. |
Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos. |
2009 |
Blood |
pmid:19864643
|
Zubia A et al. |
Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity. |
2009 |
Oncogene |
pmid:19169274
|
Meng Q et al. |
Live birth of somatic cell-cloned rabbits following trichostatin A treatment and cotransfer of parthenogenetic embryos. |
2009 |
Cloning Stem Cells |
pmid:19196041
|
Gray SG et al. |
Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications. |
2009 |
Eur. J. Cancer |
pmid:19818596
|
Zhang F et al. |
Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells. |
2009 |
Cancer Biol. Ther. |
pmid:19270532
|
Hara D et al. |
Persistent BDNF exon I-IX mRNA expression following the withdrawal of neuronal activity in neurons. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19818730
|
Tan HH and Porter AG |
p21(WAF1) negatively regulates DNMT1 expression in mammalian cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19275888
|
Li C et al. |
Induction of myelogenous leukemia cells with histone deacetylase inhibitors through down-regulating the Daxx protein expression. |
2009 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:19821084
|
Gavin DP et al. |
Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population. |
2009 |
J Psychiatr Res |
pmid:19187942
|
Liberatore RA et al. |
NF-kappaB activity is constitutively elevated in c-Abl null fibroblasts. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805123
|
Sasaki K et al. |
Real-time imaging of histone H4 hyperacetylation in living cells. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805290
|
Gibbs A et al. |
Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805354
|
Hoebeeck J et al. |
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. |
2009 |
Cancer Lett. |
pmid:18819746
|