Mukhopadhyay NK et al. |
Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer. |
2006 |
Ann. Thorac. Surg. |
pmid:16488717
|
Swanson S |
Invited commentary. |
2006 |
Ann. Thorac. Surg. |
pmid:16488718
|
Bieler A et al. |
Novel three-pronged strategy to enhance cancer cell killing in glioblastoma cell lines: histone deacetylase inhibitor, chemotherapy, and oncolytic adenovirus dl520. |
2006 |
Hum. Gene Ther. |
pmid:16409125
|
Lo PK et al. |
Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer. |
2006 |
Cancer Biol. Ther. |
pmid:16410723
|
Williams SA et al. |
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. |
2006 |
EMBO J. |
pmid:16319923
|
Zou B et al. |
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. |
2006 |
Gastroenterology |
pmid:17087954
|
Anderson I |
Deacetylase inhibitors aid recovery in muscular dystrophy. |
2006 |
Lancet Neurol |
pmid:17089447
|
Kiefer J et al. |
Mixtures of SCFA, composed according to physiologically available concentrations in the gut lumen, modulate histone acetylation in human HT29 colon cancer cells. |
2006 |
Br. J. Nutr. |
pmid:17092367
|
Bishop CL et al. |
Role for centromeric heterochromatin and PML nuclear bodies in the cellular response to foreign DNA. |
2006 |
Mol. Cell. Biol. |
pmid:16537904
|
Gagnon JF et al. |
Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer. |
2006 |
Clin. Cancer Res. |
pmid:16551870
|
Rebbaa A et al. |
The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis. |
2006 |
Cell Death Differ. |
pmid:16557274
|
Suuronen T et al. |
Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia. |
2006 |
Neurochem. Int. |
pmid:16797784
|
Wallace DM et al. |
Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:16799012
|
Pampalakis G and Sotiropoulou G |
Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. |
2006 |
Biol. Chem. |
pmid:16800739
|
Wang Y et al. |
Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. |
2006 |
Arthritis Rheum. |
pmid:16802366
|
Kong Y et al. |
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. |
2006 |
Circulation |
pmid:16735673
|
Dannenberg LO et al. |
Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. |
2006 |
Alcohol. Clin. Exp. Res. |
pmid:16737450
|
Cabrero JR et al. |
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. |
2006 |
Mol. Biol. Cell |
pmid:16738306
|
Vulcano F et al. |
HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers. |
2006 |
Exp. Cell Res. |
pmid:16739251
|
Qi H and Ratnam M |
Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. |
2006 |
Cancer Res. |
pmid:16740727
|
Scott SA et al. |
5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation. |
2006 |
Leuk. Res. |
pmid:16043219
|
Hofmann A et al. |
Epigenetic regulation of lentiviral transgene vectors in a large animal model. |
2006 |
Mol. Ther. |
pmid:16140581
|
Clem BF and Clark BJ |
Association of the mSin3A-histone deacetylase 1/2 corepressor complex with the mouse steroidogenic acute regulatory protein gene. |
2006 |
Mol. Endocrinol. |
pmid:16109738
|
Mai A et al. |
Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. |
2006 |
J. Med. Chem. |
pmid:17004718
|
Yao J et al. |
NF-kappaB signaling pathway is involved in growth inhibition, G2/M arrest and apoptosis induced by Trichostatin A in human tongue carcinoma cells. |
2006 |
Pharmacol. Res. |
pmid:17005413
|
Inoue K et al. |
Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. |
2006 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17008592
|
Baqir S and Smith LC |
Inhibitors of histone deacetylases and DNA methyltransferases alter imprinted gene regulation in embryonic stem cells. |
2006 |
Cloning Stem Cells |
pmid:17009896
|
Hong ZY et al. |
[Mechanism of apoptosis induced by trichostatin A in leukemia Molt-4 cells analyzed by microarray]. |
2006 |
Ai Zheng |
pmid:16965673
|
Jung JW et al. |
Effects of the histone deacetylases inhibitors sodium butyrate and trichostatin A on the inhibition of gap junctional intercellular communication by H2O2- and 12-O-tetradecanoylphorbol-13-acetate in rat liver epithelial cells. |
2006 |
Cancer Lett. |
pmid:16337085
|
Chen J et al. |
Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells. |
2006 |
Pharmazie |
pmid:16964716
|
Kim MY et al. |
A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16924111
|
Mühlethaler-Mottet A et al. |
Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. |
2006 |
BMC Cancer |
pmid:16930472
|
Suzuki T et al. |
Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. |
2006 |
J. Med. Chem. |
pmid:16884291
|
Kim TY et al. |
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. |
2006 |
Cancer Res. |
pmid:16885346
|
Kimura N et al. |
Alteration of developmental program in Paramecium by treatment with trichostatin a: a possible involvement of histone modification. |
2006 |
Protist |
pmid:16839811
|
Kim IA et al. |
Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53. |
2006 |
Clin. Cancer Res. |
pmid:16467109
|
Osborn NK et al. |
Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia. |
2006 |
Clin. Gastroenterol. Hepatol. |
pmid:16469682
|
Baraz L et al. |
Tumor suppressor p53 regulates heparanase gene expression. |
2006 |
Oncogene |
pmid:16474844
|
Gialitakis M et al. |
Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. |
2006 |
Nucleic Acids Res. |
pmid:16452299
|
Cecconi D et al. |
Proteomic analysis of pancreatic ductal carcinoma cells after combined treatment with gemcitabine and trichostatin A. |
2005 Nov-Dec |
J. Proteome Res. |
pmid:16335935
|
Garcia BA et al. |
Resetting the epigenetic histone code in the MRL-lpr/lpr mouse model of lupus by histone deacetylase inhibition. |
2005 Nov-Dec |
J. Proteome Res. |
pmid:16335948
|
Huang W et al. |
Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex. |
2005 |
J. Biol. Chem. |
pmid:15647279
|
Choi JH et al. |
Trichostatin A attenuates airway inflammation in mouse asthma model. |
2005 |
Clin. Exp. Allergy |
pmid:15649272
|
Varshochi R et al. |
ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line. |
2005 |
J. Biol. Chem. |
pmid:15557281
|
Goeman F et al. |
Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras. |
2005 |
Mol. Cell. Biol. |
pmid:15601862
|
Tai HH et al. |
Dynamic histone acetylation of late embryonic genes during seed germination. |
2005 |
Plant Mol. Biol. |
pmid:16307366
|
Noh EJ et al. |
Methyl CpG-binding domain protein 3 mediates cancer-selective cytotoxicity by histone deacetylase inhibitors via differential transcriptional reprogramming in lung cancer cells. |
2005 |
Cancer Res. |
pmid:16357148
|
Wetzel M et al. |
Effect of trichostatin A, a histone deacetylase inhibitor, on glioma proliferation in vitro by inducing cell cycle arrest and apoptosis. |
2005 |
J. Neurosurg. |
pmid:16383255
|
Place RF et al. |
HDACs and the senescent phenotype of WI-38 cells. |
2005 |
BMC Cell Biol. |
pmid:16250917
|
Lee JH et al. |
Interactions with p300 enhance transcriptional activation by the PDZ-domain coactivator Bridge-1. |
2005 |
J. Endocrinol. |
pmid:16293776
|
Hazzalin CA and Mahadevan LC |
Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: analysis at c-fos and c-jun. |
2005 |
PLoS Biol. |
pmid:16262446
|
Hohl M and Thiel G |
Cell type-specific regulation of RE-1 silencing transcription factor (REST) target genes. |
2005 |
Eur. J. Neurosci. |
pmid:16262660
|
Bernes S et al. |
Epigenetic and classical activation of Entamoeba histolytica heat shock protein 100 (EHsp100) expression. |
2005 |
FEBS Lett. |
pmid:16263115
|
Gao S et al. |
CpG methylation of the PAI-1 gene 5'-flanking region is inversely correlated with PAI-1 mRNA levels in human cell lines. |
2005 |
Thromb. Haemost. |
pmid:16268485
|
Li XX et al. |
Function of c-Fos-like and c-Jun-like proteins on trichostatin A-induced G2/M arrest in Physarum polycephalum. |
2005 |
Acta Biochim. Biophys. Sin. (Shanghai) |
pmid:16270156
|
Osada H et al. |
Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines. |
2005 |
Mol. Carcinog. |
pmid:16163707
|
Rogier E et al. |
A novel biological assay to detect the active form of TGF-beta in urine to monitor renal allograft rejection. |
2005 |
Kidney Int. |
pmid:16164666
|
Di-Poï N et al. |
Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins. |
2005 |
J. Biol. Chem. |
pmid:16166081
|
Spengler ML et al. |
Sumoylation of internally initiated Sp3 isoforms regulates transcriptional repression via a Trichostatin A-insensitive mechanism. |
2005 |
Cell. Signal. |
pmid:15494207
|
Lin KT et al. |
Epigenetic activation of alpha4, beta2 and beta6 integrins involved in cell migration in trichostatin A-treated Hep3B cells. |
2005 |
J. Biomed. Sci. |
pmid:16132114
|
Smardová J et al. |
CBP sensitizes v-myb-transformed monoblasts to differentiation inducers. |
2005 |
Differentiation |
pmid:16026544
|
Fandy TE et al. |
Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma. |
2005 |
Neoplasia |
pmid:16026644
|
Korutla L et al. |
The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal-like cultures. |
2005 |
J. Neurochem. |
pmid:16033423
|
Shindo N et al. |
The ESC-E(Z) complex participates in the hedgehog signaling pathway. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15652519
|
Kemp MG et al. |
The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells. |
2005 |
Nucleic Acids Res. |
pmid:15653633
|
Huang H et al. |
MEIS C termini harbor transcriptional activation domains that respond to cell signaling. |
2005 |
J. Biol. Chem. |
pmid:15654074
|
Danam RP et al. |
Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins. |
2005 |
Mol. Cancer Ther. |
pmid:15657354
|
Li Y et al. |
Histone deacetylation is required for progression through mitosis in tobacco cells. |
2005 |
Plant J. |
pmid:15659094
|
Zhao Y et al. |
Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors. |
2005 |
J. Exp. Biol. |
pmid:15695762
|
Galfi P et al. |
Divergent effects of resveratrol, a polyphenolic phytostilbene, on free radical levels and type of cell death induced by the histone deacetylase inhibitors butyrate and trichostatin A. |
2005 |
J. Steroid Biochem. Mol. Biol. |
pmid:15862948
|
Choi KH et al. |
Activation of CMV promoter-controlled glycosyltransferase and beta -galactosidase glycogenes by butyrate, tricostatin A, and 5-aza-2'-deoxycytidine. |
2005 |
Glycoconj. J. |
pmid:15864436
|
Touma SE et al. |
Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model. |
2005 |
Clin. Cancer Res. |
pmid:15867260
|
Fish JE et al. |
The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code. |
2005 |
J. Biol. Chem. |
pmid:15870070
|
Dyson MH et al. |
MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2. |
2005 |
J. Cell. Sci. |
pmid:15870105
|
Reid G et al. |
Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A. |
2005 |
Oncogene |
pmid:15870696
|
Kim MS et al. |
Sensitization to UV-induced apoptosis by the histone deacetylase inhibitor trichostatin A (TSA). |
2005 |
Exp. Cell Res. |
pmid:15878336
|
Rosenqvist N et al. |
Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain. |
2005 |
Cell Transplant |
pmid:15881422
|
Malago JJ et al. |
Anti-inflammatory properties of heat shock protein 70 and butyrate on Salmonella-induced interleukin-8 secretion in enterocyte-like Caco-2 cells. |
2005 |
Clin. Exp. Immunol. |
pmid:15958071
|
Whang YM et al. |
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells. |
2005 |
Cancer Chemother. Pharmacol. |
pmid:15959780
|
Gunin AG et al. |
Effects of histone deacetylase inhibitors on estradiol-induced proliferation and hyperplasia formation in the mouse uterus. |
2005 |
J. Endocrinol. |
pmid:15930180
|
Wittich S et al. |
Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines. |
2005 |
Anticancer Drugs |
pmid:15930892
|
Kaneda R et al. |
Genome-wide screening for target regions of histone deacetylases in cardiomyocytes. |
2005 |
Circ. Res. |
pmid:16002748
|
Kusy S et al. |
Promoter characterization of Semaphorin SEMA3F, a tumor suppressor gene. |
2005 |
Biochim. Biophys. Acta |
pmid:16005989
|
Rho JH et al. |
Doxorubicin induces apoptosis with profile of large-scale DNA fragmentation and without DNA ladder in anaplastic thyroid carcinoma cells via histone hyperacetylation. |
2005 |
Int. J. Oncol. |
pmid:16010429
|
Choi YH |
Induction of apoptosis by trichostatin A, a histone deacetylase inhibitor, is associated with inhibition of cyclooxygenase-2 activity in human non-small cell lung cancer cells. |
2005 |
Int. J. Oncol. |
pmid:16010430
|
Taddei A et al. |
The effects of histone deacetylase inhibitors on heterochromatin: implications for anticancer therapy? |
2005 |
EMBO Rep. |
pmid:15940285
|
Fishel ML et al. |
Effect of cell cycle inhibition on Cisplatin-induced cytotoxicity. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15304523
|
Wagner S and Roemer K |
Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf. |
2005 |
Biochem. Pharmacol. |
pmid:15763542
|
Kawamura T et al. |
Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes. |
2005 |
J. Biol. Chem. |
pmid:15764815
|
Xiong Y et al. |
Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells. |
2005 |
Cancer Res. |
pmid:15805266
|
Kumakura S et al. |
Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells. |
2005 |
Cancer Res. |
pmid:15805278
|
Zhao W et al. |
The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island. |
2005 |
J. Biochem. |
pmid:15809347
|
Subramanian C et al. |
Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors. |
2005 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:15778293
|
Lu ZP et al. |
Histone deacetylase inhibitor Trichostatin A reduces anti-DNA autoantibody production and represses IgH gene transcription. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15781251
|
Nishigaki M et al. |
Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays. |
2005 |
Cancer Res. |
pmid:15781621
|
Bai J et al. |
Predominant Bcl-XL knockdown disables antiapoptotic mechanisms: tumor necrosis factor-related apoptosis-inducing ligand-based triple chemotherapy overcomes chemoresistance in pancreatic cancer cells in vitro. |
2005 |
Cancer Res. |
pmid:15781649
|
Rahmani M et al. |
Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species. |
2005 |
Cancer Res. |
pmid:15781658
|
Fujisawa K et al. |
Epigenetic status and aberrant expression of the maspin gene in human hepato-biliary tract carcinomas. |
2005 |
Lab. Invest. |
pmid:15608662
|
Bottardi S et al. |
Onset and inheritance of abnormal epigenetic regulation in hematopoietic cells. |
2005 |
Hum. Mol. Genet. |
pmid:15615768
|
Ezzat S et al. |
The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility. |
2005 |
Mol. Endocrinol. |
pmid:15618287
|