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The mouse tumor cell lines EL4 and RMA display mosaic expression of NK-related and certain other surface molecules and appear to have a common origin. |
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J. Immunol. |
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2000 |
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2000 |
Curr. Biol. |
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High levels of intracellular polyamines promote histone acetyltransferase activity resulting in chromatin hyperacetylation. |
2000 |
J. Cell. Biochem. |
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2000 |
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Nucleic Acids Res. |
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Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all-trans retinoic acid. |
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Cell signaling switches HOX-PBX complexes from repressors to activators of transcription mediated by histone deacetylases and histone acetyltransferases. |
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Mol. Cell. Biol. |
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Unique anti-activator protein-1 activity of retinoic acid receptor beta. |
2000 |
Cancer Res. |
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Hemavathy K et al. |
Human Slug is a repressor that localizes to sites of active transcription. |
2000 |
Mol. Cell. Biol. |
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Jin S et al. |
Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
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A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10920185
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Mao C and Shapiro DJ |
A histone deacetylase inhibitor potentiates estrogen receptor activation of a stably integrated vitellogenin promoter in HepG2 cells. |
2000 |
Endocrinology |
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2000 |
EMBO J. |
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Heat shock protein 90 mediates protein-protein interactions between human aminoacyl-tRNA synthetases. |
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Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase. |
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Mol. Cell. Biol. |
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Cell-cycle regulation of the DNA topoisomerase IIalpha promoter is mediated by proximal CCAAT boxes: possible involvement of acetylation. |
2000 |
Gene |
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Allele-specific histone acetylation accompanies genomic imprinting of the insulin-like growth factor II receptor gene. |
2000 |
Endocrinology |
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Improved recombinant retroviral titers utilizing trichostatin A. |
2000 |
BioTechniques |
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Promoter specific sensitivity to inhibition of histone deacetylases: implications for hormonal gene control, cellular differentiation and cancer. |
2000 Mar-Apr |
Anticancer Res. |
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Histone deacetylase activity is required for the induction of the MyoD muscle cell lineage in Xenopus. |
2000 Sep-Oct |
Biol. Chem. |
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The histone deacetylase inhibitor trichostatin A influences the development of Drosophila melanogaster. |
2001 |
Cell. Mol. Life Sci. |
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An essential role of histone deacetylases in postembryonic organ transformations in Xenopus laevis. |
2001 |
Int. J. Mol. Med. |
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Identification of factors mediating the developmental regulation of the early acting -3.9 kb chicken lysozyme enhancer element. |
2001 |
Nucleic Acids Res. |
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Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines. |
2001 |
Jpn. J. Cancer Res. |
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Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. |
2001 |
J. Biol. Chem. |
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DNA methylation regulates placental lactogen I gene expression. |
2001 |
Endocrinology |
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Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. |
2001 |
Endocrinology |
pmid:11517158
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Jorgensen JS and Nilson JH |
AR suppresses transcription of the alpha glycoprotein hormone subunit gene through protein-protein interactions with cJun and activation transcription factor 2. |
2001 |
Mol. Endocrinol. |
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Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. |
2001 |
J. Biol. Chem. |
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Functional knockout of the corepressor CtBP by the second exon of adenovirus E1a relieves repression of transcription. |
2001 |
Exp. Cell Res. |
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Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5. |
2001 |
J. Biol. Chem. |
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Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
2001 |
Nucleic Acids Res. |
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Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. |
2001 |
Mol. Cell. Biol. |
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The role of acetylation in rDNA transcription. |
2001 |
Nucleic Acids Res. |
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Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. |
2001 |
Oncogene |
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Chromatin remodeling at the Ig loci prior to V(D)J recombination. |
2001 |
J. Immunol. |
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Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. |
2001 |
Science |
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A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. |
2001 |
Genetics |
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3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. |
2001 |
J. Med. Chem. |
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Evidence for gene silencing in Haemophilus influenzae. |
2001 |
Mutat. Res. |
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Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. |
2001 |
Cancer Res. |
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Baur JA et al. |
Telomere position effect in human cells. |
2001 |
Science |
pmid:11408657
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Position effects are influenced by the orientation of a transgene with respect to flanking chromatin. |
2001 |
Mol. Cell. Biol. |
pmid:11113204
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Mehra-Chaudhary R et al. |
Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter. |
2001 |
Biochem. J. |
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Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. |
2001 |
Cancer Res. |
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Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11134513
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Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. |
2001 |
J. Biol. Chem. |
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Mechanisms involved in the homologous down-regulation of transcription of the follicle-stimulating hormone receptor gene in Sertoli cells. |
2001 |
Mol. Cell. Endocrinol. |
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Chang YC et al. |
Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. |
2001 |
Mol. Cell. Biol. |
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