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Breast Cancer Res. Treat. |
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Histone deacetylase inhibition improves meiotic competence but not developmental competence in growing pig oocytes. |
2009 |
Zygote |
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2009 |
BMC Cancer |
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Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes. |
2009 |
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Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. |
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Clin. Cancer Res. |
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2009 |
Bioorg. Med. Chem. Lett. |
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Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. |
2009 |
J Psychiatry Neurosci |
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The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation. |
2009 |
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Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors. |
2009 |
Prostate |
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Histone acetyltransferase GCN5 interferes with the miRNA pathway in Arabidopsis. |
2009 |
Cell Res. |
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HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: potential implications for the immunosurveillance of cancer. |
2009 |
Oncogene |
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Role of histone acetylation in the activity-dependent regulation of sulfiredoxin and sestrin 2. |
2009 |
Epigenetics |
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2009 Jul-Aug |
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Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells. |
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Trichostatin A sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by down-regulation of c-FLIPL via inhibition of EGFR pathway. |
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ATF-2 regulates lipopolysaccharide-induced transcription in macrophage cells. |
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Biochem. Biophys. Res. Commun. |
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2009 |
Stem Cells |
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Anti-inflammatory effect of Trichostatin-A on murine bone marrow-derived macrophages. |
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Haematologica |
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2009 |
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2009 |
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2009 |
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E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. |
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Gastroenterology |
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Histone deacetylase inhibitors promote neurosteroid-mediated cell differentiation and enhance serotonin-stimulated brain-derived neurotrophic factor gene expression in rat C6 glioma cells. |
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Enhancement of histone acetylation by trichostatin A during in vitro fertilization of bovine oocytes affects cell number of the inner cell mass of the resulting blastocysts. |
2009 |
Zygote |
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Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. |
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2009 |
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CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. |
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PLoS ONE |
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Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells. |
2009 |
Anticancer Res. |
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Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells. |
2009 |
Int. J. Cancer |
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The improvement of adenovirus vector production by increased expression of coxsackie adenovirus receptor. |
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Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. |
2009 |
Carcinogenesis |
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Identification and functional characterization of the promoter of the mouse sodium-activated sodium channel Na(x) gene (Scn7a). |
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Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum. |
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The anticancer effect of histone deacetylase inhibitors and combination with the cytotoxic agents in lung cancer cells: biological analyses for future clinical application. |
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JBIR-17, a novel trichostatin analog from Streptomyces sp. 26634. |
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J. Antibiot. |
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E1A has no effect on LPS-induced IL-6 secretion in rat alveolar epithelial cells. |
2009 |
Respiration |
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Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. |
2009 |
Proteomics |
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Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications. |
2009 |
Biochem. Biophys. Res. Commun. |
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Changes in acetylation on lysine 12 of histone H4 (acH4K12) of murine oocytes during maternal aging may affect fertilization and subsequent embryo development. |
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N-Hydroxy-(4-oxime)-cinnamide: a versatile scaffold for the synthesis of novel histone deacetylase [correction of deacetilase] (HDAC) inhibitors. |
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Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells. |
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The essential role of Oct-2 in LPS-induced expression of iNOS in RAW 264.7 macrophages and its regulation by trichostatin A. |
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Am. J. Physiol., Cell Physiol. |
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Mol. Biol. Rep. |
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p21(WAF1) negatively regulates DNMT1 expression in mammalian cells. |
2009 |
Biochem. Biophys. Res. Commun. |
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Cancer Biol. Ther. |
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Effect of trychostatin A treatment on gene expression in cloned mouse embryos. |
2009 |
Theriogenology |
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Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. |
2009 |
PLoS ONE |
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2009 |
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BMC Dev. Biol. |
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2009 |
Cloning Stem Cells |
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J Psychiatr Res |
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The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2'-deoxycytidine. |
2009 |
Zygote |
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Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. |
2009 |
Chromosome Res. |
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Using histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance. |
2009 Mar-Apr |
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Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. |
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Oncogene |
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2009 |
Invest. Ophthalmol. Vis. Sci. |
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Cell Cycle |
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2009 Mar-Apr |
Blood Cells Mol. Dis. |
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Histone deacetylase inhibitor, trichostatin A, affects gene expression patterns during morphogenesis of chicken limb buds in vivo. |
2009 |
Cells Tissues Organs (Print) |
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Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea. |
2009 |
J. Neurochem. |
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2008 |
Tsitologiia |
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[Nucleosome positioning within neomycinphosphotransferase gene (NPTII) on yeast plasmid in repressed and active state]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
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[NF-kappaB modulates activation of the BMP-2 gene by trichostatin A]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
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Endothelin-stimulated human B-type natriuretic peptide gene expression is mediated by Yin Yang 1 in association with histone deacetylase 2. |
2009 |
Hypertension |
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3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment. |
2009 |
Eur J Med Chem |
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Tubulin acetylation favors Hsp90 recruitment to microtubules and stimulates the signaling function of the Hsp90 clients Akt/PKB and p53. |
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Cell. Signal. |
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Promoter CpG methylation in cancer cells contributes to the regulation of MUC4. |
2009 |
Br. J. Cancer |
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Histone deacetylase inhibitors blocked activation and caused senescence of corneal stromal cells. |
2008 |
Mol. Vis. |
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Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. |
2009 |
Arterioscler. Thromb. Vasc. Biol. |
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HDAC3 influences phosphorylation of STAT3 at serine 727 by interacting with PP2A. |
2009 |
Biochem. Biophys. Res. Commun. |
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Dicer is regulated by cellular stresses and interferons. |
2009 |
Mol. Immunol. |
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Identification of novel targets for PGC-1alpha and histone deacetylase inhibitors in neuroblastoma cells. |
2009 |
Biochem. Biophys. Res. Commun. |
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Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cells. |
2008 |
Exp. Mol. Med. |
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Effect of trichostatin a on viability and microRNA expression in human pancreatic cancer cell line BxPC-3. |
2008 |
Exp. Oncol. |
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Novel HDAC6 isoform selective chiral small molecule histone deacetylase inhibitors. |
2009 |
Bioorg. Med. Chem. Lett. |
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Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation. |
2009 |
J. Med. Chem. |
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Inhibition of histone deacetylases antagonized FGF2 and IL-1beta effects on MMP expression in human articular chondrocytes. |
2009 |
Growth Factors |
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Identification of two independent SUMO-interacting motifs in Daxx: evolutionary conservation from Drosophila to humans and their biochemical functions. |
2009 |
Cell Cycle |
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Trichostatin A enhances OGD-astrocyte viability by inhibiting inflammatory reaction mediated by NF-kappaB. |
2009 |
Brain Res. Bull. |
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Stable protein, unstable plaque? |
2009 |
J. Mol. Cell. Cardiol. |
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Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. |
2009 |
Blood |
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Schistosoma mansoni: developmental arrest of miracidia treated with histone deacetylase inhibitors. |
2009 |
Exp. Parasitol. |
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[Effects of trichostatin A and paclitaxel on apoptosis and microtubule stabilization in endometrial carcinoma cells: an in vitro research]. |
2008 |
Zhonghua Yi Xue Za Zhi |
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Somatic cell nuclear transfer in the mouse. |
2009 |
Methods Mol. Biol. |
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Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. |
2008 |
Nutr Res |
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[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP]. |
2008 |
Ai Zheng |
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Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation. |
2009 May-Jun |
Photochem. Photobiol. |
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Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells. |
2008 |
Clin Lung Cancer |
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Caspase cleavage of Itch in chronic lymphocytic leukemia cells. |
2009 |
Biochem. Biophys. Res. Commun. |
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