Chen Z et al. |
BCL11A represses HBG transcription in K562 cells. |
2009 Mar-Apr |
Blood Cells Mol. Dis. |
pmid:19153051
|
Wang L et al. |
Using histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance. |
2009 Mar-Apr |
Immunol. Cell Biol. |
pmid:19172156
|
Pollack BP et al. |
Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation. |
2009 May-Jun |
Photochem. Photobiol. |
pmid:19076306
|
Luo W et al. |
Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer. |
2010 |
Cancer Res. |
pmid:20587525
|
Zaman MS et al. |
The functional significance of microRNA-145 in prostate cancer. |
2010 |
Br. J. Cancer |
pmid:20588276
|
Shu ST et al. |
Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells. |
2010 |
Anticancer Res. |
pmid:20651337
|
Paddock MN et al. |
The BRCT domain of PARP-1 is required for immunoglobulin gene conversion. |
2010 |
PLoS Biol. |
pmid:20652015
|
Mossman D et al. |
Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists. |
2010 |
BMC Cancer |
pmid:20618997
|
Ma J et al. |
Promoter hypermethylation and histone hypoacetylation contribute to pancreatic-duodenal homeobox 1 silencing in gastric cancer. |
2010 |
Carcinogenesis |
pmid:20622005
|
Oliveira CS et al. |
Effects of histone hyperacetylation on the preimplantation development of male and female bovine embryos. |
2010 |
Reprod. Fertil. Dev. |
pmid:20591338
|
Suo L et al. |
Changes in acetylation on lysine 12 of histone H4 (acH4K12) of murine oocytes during maternal aging may affect fertilization and subsequent embryo development. |
2010 |
Fertil. Steril. |
pmid:19285668
|
Xia J et al. |
Epigenetic modification of vomeronasal (V2r) precursor neurons by histone deacetylation. |
2010 |
Neuroscience |
pmid:20594945
|
Tian F et al. |
Effects of histone deacetylase inhibitor Trichostatin A on epigenetic changes and transcriptional activation of Bdnf promoter 1 by rat hippocampal neurons. |
2010 |
Ann. N. Y. Acad. Sci. |
pmid:20633124
|
Rössler R et al. |
Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons. |
2010 |
Neuroscience |
pmid:20643196
|
Rahman R et al. |
Histone deacetylase inhibition attenuates cell growth with associated telomerase inhibition in high-grade childhood brain tumor cells. |
2010 |
Mol. Cancer Ther. |
pmid:20643785
|
Tong JH et al. |
Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma. |
2010 |
BMC Cancer |
pmid:20525238
|
Han DS et al. |
Transcription activation of myostatin by trichostatin A in differentiated C2C12 myocytes via ASK1-MKK3/4/6-JNK and p38 mitogen-activated protein kinase pathways. |
2010 |
J. Cell. Biochem. |
pmid:20568119
|
Trtkova K et al. |
Binding of AR to SMRT/N-CoR complex and its co-operation with PSA promoter in prostate cancer cells treated with natural histone deacetylase inhibitor NaB. |
2010 |
Neoplasma |
pmid:20568894
|
Legartova S et al. |
Expression of RAN, ZHX-2, and CHC1L genes in multiple myeloma patients and in myeloma cell lines treated with HDAC and Dnmts inhibitors. |
2010 |
Neoplasma |
pmid:20568903
|
Chen J et al. |
Interplay of bromodomain and histone acetylation in the regulation of p300-dependent genes. |
2010 |
Epigenetics |
pmid:20505343
|
Liu YW et al. |
Inhibition of LPS-induced C/EBP delta by trichostatin A has a positive effect on LPS-induced cyclooxygenase 2 expression in RAW264.7 cells. |
2010 |
J. Cell. Biochem. |
pmid:20506344
|
Kitamoto S et al. |
Promoter hypomethylation contributes to the expression of MUC3A in cancer cells. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20510874
|
Liang Q et al. |
The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers. |
2010 |
Int. J. Cancer |
pmid:20112338
|
Beedanagari SR et al. |
Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines. |
2010 |
Toxicol. Lett. |
pmid:20116417
|
Lu Y et al. |
Trichostatin A, a histone deacetylase inhibitor, reduces lesion growth and hyperalgesia in experimentally induced endometriosis in mice. |
2010 |
Hum. Reprod. |
pmid:20118114
|
Davies GF et al. |
Troglitazone inhibits histone deacetylase activity in breast cancer cells. |
2010 |
Cancer Lett. |
pmid:19699029
|
Hajji N et al. |
Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide. |
2010 |
Oncogene |
pmid:20118981
|
Suh HS et al. |
Histone deacetylase inhibitors suppress the expression of inflammatory and innate immune response genes in human microglia and astrocytes. |
2010 |
J Neuroimmune Pharmacol |
pmid:20157787
|
Crosson CE et al. |
Inhibition of histone deacetylase protects the retina from ischemic injury. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
pmid:20164449
|
Jang ER et al. |
ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response. |
2010 |
Exp. Mol. Med. |
pmid:20164679
|
Desai D et al. |
SelSA, selenium analogs of SAHA as potent histone deacetylase inhibitors. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20167479
|
Ishimaru N et al. |
Differential epigenetic regulation of BDNF and NT-3 genes by trichostatin A and 5-aza-2'-deoxycytidine in Neuro-2a cells. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20188708
|
Popova AP et al. |
Autocrine production of TGF-beta1 promotes myofibroblastic differentiation of neonatal lung mesenchymal stem cells. |
2010 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:20190033
|
Wu Y et al. |
Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. |
2010 |
BMC Cancer |
pmid:20132554
|
Kim TH et al. |
The histone deacetylase inhibitor, trichostatin A, inhibits the development of 2,4-dinitrofluorobenzene-induced dermatitis in NC/Nga mice. |
2010 |
Int. Immunopharmacol. |
pmid:20728595
|
Aoyama M et al. |
Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways. |
2010 |
Nutrition |
pmid:20004081
|
Ji P et al. |
Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts. |
2010 |
Haematologica |
pmid:20823130
|
Nunes MJ et al. |
Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription. |
2010 |
J. Neurochem. |
pmid:20096088
|
Weng YI et al. |
Epigenetic influences of low-dose bisphenol A in primary human breast epithelial cells. |
2010 |
Toxicol. Appl. Pharmacol. |
pmid:20678512
|
Aizawa S and Yamamuro Y |
Involvement of histone acetylation in the regulation of choline acetyltransferase gene in NG108-15 neuronal cells. |
2010 |
Neurochem. Int. |
pmid:20100532
|
Tamannai M et al. |
The inhibitor of growth 1 (ING1) is involved in trichostatin A-induced apoptosis and caspase 3 signaling in p53-deficient glioblastoma cells. |
2010 |
Oncol. Res. |
pmid:20681406
|
Wu J et al. |
Trichostatin A sensitizes cisplatin-resistant A549 cells to apoptosis by up-regulating death-associated protein kinase. |
2010 |
Acta Pharmacol. Sin. |
pmid:20048748
|
Sonnemann J et al. |
Serine proteases in histone deacetylase inhibitor-induced apoptosis. |
2010 |
Mol. Cancer Ther. |
pmid:20682651
|
Hebbel RP et al. |
The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice. |
2010 |
Blood |
pmid:20053759
|
Fu J et al. |
Discovery of 1H-benzo[d][1,2,3]triazol-1-yl 3,4,5-trimethoxybenzoate as a potential antiproliferative agent by inhibiting histone deacetylase. |
2010 |
Bioorg. Med. Chem. |
pmid:21067930
|
He R et al. |
Synthesis and biological evaluation of triazol-4-ylphenyl-bearing histone deacetylase inhibitors as anticancer agents. |
2010 |
J. Med. Chem. |
pmid:20055418
|
Nicodeme E et al. |
Suppression of inflammation by a synthetic histone mimic. |
2010 |
Nature |
pmid:21068722
|
Ajiro K et al. |
Reciprocal epigenetic modification of histone H2B occurs in chromatin during apoptosis in vitro and in vivo. |
2010 |
Cell Death Differ. |
pmid:20057502
|
Auzzas L et al. |
Non-natural macrocyclic inhibitors of histone deacetylases: design, synthesis, and activity. |
2010 |
J. Med. Chem. |
pmid:21073160
|
Choi YS et al. |
Differentiation of human adipose-derived stem cells into beating cardiomyocytes. |
2010 |
J. Cell. Mol. Med. |
pmid:20070436
|
Lee KJ et al. |
Downregulation of a tumor suppressor RECK by hypoxia through recruitment of HDAC1 and HIF-1alpha to reverse HRE site in the promoter. |
2010 |
Biochim. Biophys. Acta |
pmid:20080132
|
Grabiec AM et al. |
Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue. |
2010 |
J. Immunol. |
pmid:20100935
|
Chatterjee A et al. |
An efficient synthesis of (+/-)-trichostatic Acid and analogues: a new route to (+/-)-trichostatin A. |
2010 |
Org. Lett. |
pmid:20104892
|
Kicic A et al. |
Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium. |
2010 |
Am. J. Respir. Crit. Care Med. |
pmid:20110557
|
Su Y et al. |
Human RecQL4 helicase plays critical roles in prostate carcinogenesis. |
2010 |
Cancer Res. |
pmid:21045146
|
Taura A et al. |
Histone deacetylase inhibition enhances adenoviral vector transduction in inner ear tissue. |
2010 |
Neuroscience |
pmid:20060033
|
Xu J et al. |
CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors. |
2010 |
Breast Cancer Res. Treat. |
pmid:19466541
|
Li Y et al. |
Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells. |
2010 |
Mol. Cancer |
pmid:20946668
|
Gupta PK et al. |
Inhibitors selective for HDAC6 in enzymes and cells. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20947351
|
Watson JA et al. |
Hyperacetylation in prostate cancer induces cell cycle aberrations, chromatin reorganization and altered gene expression profiles. |
2010 |
J. Cell. Mol. Med. |
pmid:19583812
|
Song S et al. |
Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1. |
2010 |
Cardiovasc. Res. |
pmid:19633316
|
Eskeland R et al. |
Histone acetylation and the maintenance of chromatin compaction by Polycomb repressive complexes. |
2010 |
Cold Spring Harb. Symp. Quant. Biol. |
pmid:21502416
|
Shiau RJ et al. |
Genistein and beta-carotene enhance the growth-inhibitory effect of trichostatin A in A549 cells. |
2010 |
Eur J Nutr |
pmid:19639378
|
Zein S et al. |
Identification of fetal hemoglobin-inducing agents using the human leukemia KU812 cell line. |
2010 |
Exp. Biol. Med. (Maywood) |
pmid:20975082
|
Chao KC et al. |
Anti-tumor activity of histone deacetylase inhibitors and the effect on ATP-binding cassette in ovarian carcinoma cells. |
2010 |
Eur. J. Gynaecol. Oncol. |
pmid:20882882
|
Lee CS et al. |
18β-Glycyrrhetinic acid potentiates apoptotic effect of trichostatin A on human epithelial ovarian carcinoma cell lines. |
2010 |
Eur. J. Pharmacol. |
pmid:20868669
|
Yuan GB et al. |
Combined effects of all-trans-retinoic acid and trichostatin A on the induction of differentiation of thyroid carcinoma cells. |
2010 |
Chin J Cancer |
pmid:20346212
|
Wang QH et al. |
Opposite effects of Trichostatin A on activation of mast cells by different stimulants. |
2010 |
FEBS Lett. |
pmid:20371366
|
Simboeck E et al. |
A phosphorylation switch regulates the transcriptional activation of cell cycle regulator p21 by histone deacetylase inhibitors. |
2010 |
J. Biol. Chem. |
pmid:20952396
|
Robertson DM et al. |
C-terminal cleavage of DeltaNp63alpha is associated with TSA-induced apoptosis in immortalized corneal epithelial cells. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
pmid:20375332
|
Halili MA et al. |
Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. |
2010 |
J. Leukoc. Biol. |
pmid:20200406
|
Karagiannis TC et al. |
Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes. |
2010 |
Aging (Albany NY) |
pmid:20930262
|
Reichrath S et al. |
Notch- and vitamin D signaling in 1,25(OH)2D3-resistant glioblastoma multiforme (GBM) cell lines. |
2010 |
J. Steroid Biochem. Mol. Biol. |
pmid:20206691
|
Milagre I et al. |
Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination. |
2010 |
J. Alzheimers Dis. |
pmid:20930312
|
Bertrand P |
Inside HDAC with HDAC inhibitors. |
2010 |
Eur J Med Chem |
pmid:20223566
|
Gao A et al. |
Methylation of PARP-1 promoter involved in the regulation of benzene-induced decrease of PARP-1 mRNA expression. |
2010 |
Toxicol. Lett. |
pmid:20230882
|
Majid S et al. |
Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer. |
2010 |
Cancer Res. |
pmid:20332239
|
Khobta A et al. |
Gene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region. |
2010 |
Nucleic Acids Res. |
pmid:20338881
|
Kim SH et al. |
Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein. |
2010 |
Breast Cancer Res. |
pmid:20388208
|
Marumo T et al. |
Histone deacetylase modulates the proinflammatory and -fibrotic changes in tubulointerstitial injury. |
2010 |
Am. J. Physiol. Renal Physiol. |
pmid:19906951
|
Yakovlev A et al. |
Epigenetic regulation of caspase-3 gene expression in rat brain development. |
2010 |
Gene |
pmid:19909801
|
Freidkin I et al. |
Effects of histone deacetylase inhibitors on rat mesangial cells. |
2010 |
Am. J. Physiol. Renal Physiol. |
pmid:19923417
|
Perisic T et al. |
Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes. |
2010 |
Neuropsychopharmacology |
pmid:19924110
|
Kitano A et al. |
Therapeutic potential of trichostatin A to control inflammatory and fibrogenic disorders of the ocular surface. |
2010 |
Mol. Vis. |
pmid:21203344
|
Sponziello M et al. |
Regulation of sodium/iodide symporter and lactoperoxidase expression in four human breast cancer cell lines. |
2010 |
J. Endocrinol. Invest. |
pmid:19794300
|
Himaki T et al. |
Effects of trichostatin A on in vitro development and transgene function in somatic cell nuclear transfer embryos derived from transgenic Clawn miniature pig cells. |
2010 |
Anim. Sci. J. |
pmid:20887307
|
Wu P et al. |
Ubiquitin B: an essential mediator of trichostatin A-induced tumor-selective killing in human cancer cells. |
2010 |
Cell Death Differ. |
pmid:19798105
|
Peidis P et al. |
HDAC pharmacological inhibition promotes cell death through the eIF2α kinases PKR and GCN2. |
2010 |
Aging (Albany NY) |
pmid:21076179
|
Di Renzo F et al. |
VPA-related axial skeletal defects and apoptosis: a proposed event cascade. |
2010 |
Reprod. Toxicol. |
pmid:19850124
|
Patil V et al. |
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group. |
2010 |
Bioorg. Med. Chem. |
pmid:19914074
|
Choi JH et al. |
TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:19914212
|
Dong G et al. |
Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells. |
2010 |
Am. J. Physiol. Renal Physiol. |
pmid:19889954
|
Li X et al. |
Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation. |
2010 |
Br. J. Haematol. |
pmid:19807731
|
Ninios YP et al. |
Differential sensitivity of human leukemic cell lines to the histone deacetylase inhibitor, trichostatin A. |
2010 |
Leuk. Res. |
pmid:19782399
|
Higashiyama R et al. |
Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis. |
2010 |
Mod Rheumatol |
pmid:19784544
|
Law AY and Wong CK |
Stanniocalcin-2 is a HIF-1 target gene that promotes cell proliferation in hypoxia. |
2010 |
Exp. Cell Res. |
pmid:19786016
|
Estiu G et al. |
On the inhibition of histone deacetylase 8. |
2010 |
Bioorg. Med. Chem. |
pmid:20472442
|
Kobori A et al. |
Butyrate stimulates IL-32alpha expression in human intestinal epithelial cell lines. |
2010 |
World J. Gastroenterol. |
pmid:20480520
|
Kiyokawa S et al. |
New orally bioavailable 2-aminobenzamide-type histone deacetylase inhibitor possessing a (2-hydroxyethyl)(4-(thiophen-2-yl)benzyl)amino group. |
2010 |
Bioorg. Med. Chem. |
pmid:20452226
|
Barua S and Rege K |
The influence of mediators of intracellular trafficking on transgene expression efficacy of polymer-plasmid DNA complexes. |
2010 |
Biomaterials |
pmid:20452664
|