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High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma. |
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J. Clin. Pathol. |
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Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells. |
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Mol. Cancer Res. |
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Activities of maturation-promoting factor (MPF) and mitogen-activated protein kinase (MAPK) are not required for the global histone deacetylation observed after germinal vesicle breakdown (GVBD) in porcine oocytes. |
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Reproduction |
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Effect of downregulation of survivin expression on radiosensitivity of human epidermoid carcinoma cells. |
2006 |
Int. J. Radiat. Oncol. Biol. Phys. |
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Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells. |
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Oncol. Rep. |
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Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells. |
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Mol. Cancer |
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Epigenetic abnormalities of the mouse paternal zygotic genome associated with microinsemination of round spermatids. |
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Dev. Biol. |
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Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes. |
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Mol. Cell. Probes |
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Dual effects of histone deacetylase inhibition by trichostatin A on endothelial nitric oxide synthase expression in endothelial cells. |
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Biochem. Biophys. Res. Commun. |
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Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatin. |
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Mol. Biol. Cell |
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Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. |
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J. Med. Chem. |
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Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. |
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Mol. Cell. Biol. |
pmid:16354677
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Significant improvement of mouse cloning technique by treatment with trichostatin A after somatic nuclear transfer. |
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Biochem. Biophys. Res. Commun. |
pmid:16356478
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Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells. |
2006 |
Endocr. Relat. Cancer |
pmid:17158768
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TSA-induced cell death in prostate cancer cell lines is caspase-2 dependent and involves the PIDDosome. |
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Cancer Biol. Ther. |
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[Basic research for renal regeneration]. |
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Nippon Rinsho |
pmid:16895225
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Inhibition of histone deacetylation protects wild-type but not gelsolin-deficient neurons from oxygen/glucose deprivation. |
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J. Neurochem. |
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Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. |
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FASEB J. |
pmid:16246867
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Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. |
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Biol. Chem. |
pmid:16800739
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Wang Y et al. |
Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. |
2006 |
Arthritis Rheum. |
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Trichostatin A cooperates with Fas-mediated signal to induce apoptosis in rheumatoid arthritis synovial fibroblasts. |
2006 |
J. Rheumatol. |
pmid:16755652
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Involvement of caspase activation and mitochondrial stress in trichostatin A-induced apoptosis of Burkitt's lymphoma cell line, Akata. |
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J. Cell. Biochem. |
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RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. |
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Cancer Res. |
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The transcriptional regulation role of BRD7 by binding to acetylated histone through bromodomain. |
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J. Cell. Biochem. |
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Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. |
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Cancer Res. |
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Estrogen receptor-alpha methylation predicts melanoma progression. |
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Cancer Res. |
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Deficient expression of the DPD gene is caused by epigenetic modification in biliary tract cancer cells, and induces high sensitivity to 5-FU treatment. |
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Int. J. Oncol. |
pmid:16820886
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Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. |
2006 |
Cancer Res. |
pmid:16740727
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Nusinzon I and Horvath CM |
Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation. |
2006 |
Mol. Cell. Biol. |
pmid:16581785
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Identification of novel target genes by an epigenetic reactivation screen of renal cancer. |
2006 |
Cancer Res. |
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Histone deacetylase inhibitors suppress the inducibility of nuclear factor-kappaB by tumor necrosis factor-alpha receptor-1 down-regulation. |
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Cancer Res. |
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Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors. |
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Virol. J. |
pmid:16603064
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E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer. |
2006 |
Oncogene |
pmid:16158053
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Hwang DY and Ismail-Beigi F |
Control of Glut1 promoter activity under basal conditions and in response to hyperosmolarity: role of Sp1. |
2006 |
Am. J. Physiol., Cell Physiol. |
pmid:16162661
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Kim MY et al. |
Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. |
2006 |
Mol. Endocrinol. |
pmid:16497729
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Leng Y and Chuang DM |
Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. |
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J. Neurosci. |
pmid:16837598
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LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression. |
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FASEB J. |
pmid:16816106
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[Mechanism of apoptosis induced by trichostatin A in leukemia Molt-4 cells analyzed by microarray]. |
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Ai Zheng |
pmid:16965673
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Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. |
2006 |
Clin. Cancer Res. |
pmid:16609009
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Ryu JK et al. |
SK-7041, a new histone deacetylase inhibitor, induces G2-M cell cycle arrest and apoptosis in pancreatic cancer cell lines. |
2006 |
Cancer Lett. |
pmid:16009488
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Alteration of developmental program in Paramecium by treatment with trichostatin a: a possible involvement of histone modification. |
2006 |
Protist |
pmid:16839811
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MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16847267
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Zaveri NT et al. |
Regulation of the prepronociceptin gene and its effect on neuronal differentiation. |
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Gene |
pmid:16935438
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Dokras A et al. |
Epigenetic regulation of maspin expression in the human placenta. |
2006 |
Mol. Hum. Reprod. |
pmid:16936308
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Yamamura K et al. |
Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis. |
2006 |
Br. J. Haematol. |
pmid:16939493
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Das PM et al. |
Methylation mediated silencing of TMS1/ASC gene in prostate cancer. |
2006 |
Mol. Cancer |
pmid:16848908
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Puppin C et al. |
HEX expression and localization in normal mammary gland and breast carcinoma. |
2006 |
BMC Cancer |
pmid:16854221
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Dannenberg LO and Edenberg HJ |
Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation. |
2006 |
BMC Genomics |
pmid:16854234
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