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Histone deacetylase inhibitors such as sodium butyrate and trichostatin A inhibit vascular endothelial growth factor (VEGF) secretion from human glioblastoma cells. |
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Cancer Cell |
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Curr Opin Chem Biol |
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The expression of gamma-glutamyltransferase in rat colon carcinoma cells is distinctly regulated during differentiation and oxidative stress. |
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A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. |
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DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines. |
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Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation. |
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Biochemistry |
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Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation. |
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Circ. Res. |
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Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention. |
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Cancer Res. |
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NuA4 subunit Yng2 function in intra-S-phase DNA damage response. |
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Mol. Cell. Biol. |
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Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. |
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Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. |
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Caprylic acid and medium-chain triglycerides inhibit IL-8 gene transcription in Caco-2 cells: comparison with the potent histone deacetylase inhibitor trichostatin A. |
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Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. |
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Mol. Genet. Metab. |
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2001 Jul-Sep |
Acta Gastroenterol. Belg. |
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Mol. Endocrinol. |
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Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. |
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Science |
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