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2012 |
Biochem. Biophys. Res. Commun. |
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Neuroreport |
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2012 |
Epigenetics |
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Histone deacetylase activity is required for human oligodendrocyte progenitor differentiation. |
2012 |
Glia |
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2012 |
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Epigenetic modification of TLRs in leukocytes is associated with increased susceptibility to Salmonella enteritidis in chickens. |
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Histone deacetylase inhibitors promote mice corneal allograft survival through alteration of CD4+ effector T cells and induction of Foxp3+ regulatory T cells. |
2012 May-Jun |
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Hypoxia-induced deacetylation is required for tetraploid differentiation in response to testicular ischemia-reperfusion (IR) injury. |
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2012 Nov-Dec |
Biochim. Biophys. Acta |
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Protocadherin 10 is frequently downregulated by promoter methylation and functions as a tumor suppressor gene in non-small cell lung cancer. |
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Cancer Biomark |
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HDAC inhibition decreases XIST expression on female IVP bovine blastocysts. |
2013 |
Reproduction |
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2013 |
Mol. Cell. Biochem. |
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Histone deacetylase inhibition activates transgene expression from integration-defective lentiviral vectors in dividing and non-dividing cells. |
2013 |
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Trichostatin A induces apoptotic cell death of HeLa cells in a Bcl-2 and oxidative stress-dependent manner. |
2013 |
Int. J. Oncol. |
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Recent advancements in cloning by somatic cell nuclear transfer. |
2013 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
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5-aza-2'-deoxycytidine has minor effects on differentiation in human thyroid cancer cell lines, but modulates genes that are involved in adaptation in vitro. |
2013 |
Thyroid |
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High mobility group box 1 released from necrotic cells enhances regrowth and metastasis of cancer cells that have survived chemotherapy. |
2013 |
Eur. J. Cancer |
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Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation. |
2013 |
Arthritis Rheum. |
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Scavenger receptor class A member 3 (SCARA3) in disease progression and therapy resistance in multiple myeloma. |
2013 |
Leuk. Res. |
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Epigenetic regulation of canonical TNFα pathway by HDAC1 determines survival of cardiac myocytes. |
2013 |
Am. J. Physiol. Heart Circ. Physiol. |
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Preincubation of pituitary tumor cells with the epidrugs zebularine and trichostatin A are permissive for retinoic acid-augmented expression of the BMP-4 and D2R genes. |
2013 |
Endocrinology |
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HDAC inhibitors prevent the induction of the immediate-early gene FOSL1, but do not alter the nucleosome response. |
2013 |
FEBS Lett. |
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Prevention of cytotoxicity of nickel by quercetin: the role of reactive oxygen species and histone acetylation. |
2013 |
Toxicol Ind Health |
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HDAC inhibitor trichostatin A suppresses esophageal squamous cell carcinoma metastasis through HADC2 reduced MMP-2/9. |
2013 |
Clin Invest Med |
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Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells. |
2013 |
Cell Prolif. |
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Epithelial-mesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cells. |
2013 |
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Trichostatin A, an HDAC class I/II inhibitor, promotes Pi-induced vascular calcification via up-regulation of the expression of alkaline phosphatase. |
2013 |
J. Atheroscler. Thromb. |
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Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. |
2013 |
Mol. Carcinog. |
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Inhibition of histone deacetylase activity suppresses IFN-γ induction of tripartite motif 22 via CHIP-mediated proteasomal degradation of IRF-1. |
2013 |
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Antiviral Res. |
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2013 |
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2013 |
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Nat. Rev. Neurosci. |
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HDAC inhibition elicits myocardial protective effect through modulation of MKK3/Akt-1. |
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PLoS ONE |
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2013 |
Bioorg. Med. Chem. |
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2013 |
Vet. Immunol. Immunopathol. |
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Direct differentiation of hepatic stem-like WB cells into insulin-producing cells using small molecules. |
2013 |
Sci Rep |
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Regulation of primitive hematopoiesis by class I histone deacetylases. |
2013 |
Dev. Dyn. |
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In vivo effects of Trichostatin A - A histone deacetylase inhibitor - On chromatin remodeling during Triturus cristatus spermatogenesis. |
2013 |
Anim. Reprod. Sci. |
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Compound K, a metabolite of ginseng saponin, inhibits colorectal cancer cell growth and induces apoptosis through inhibition of histone deacetylase activity. |
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Inhibition of histone deacetylase in utero causes sociability deficits in postnatal mice. |
2013 |
Behav. Brain Res. |
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Suppressed expression of NDRG2 correlates with poor prognosis in pancreatic cancer. |
2013 |
Biochem. Biophys. Res. Commun. |
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Histone deacetylase inhibitors induce human renal cell carcinoma cell apoptosis through p-JNK activation. |
2013 |
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[Tricostantin A inhibits self-renewal of breast cancer stem cells in vitro]. |
2013 |
Nan Fang Yi Ke Da Xue Xue Bao |
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The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial-mesenchymal transition of lens epithelial cells. |
2013 |
Cell Death Dis |
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Identification of a novel human testicular interstitial gene, RNF148, and its expression regulated by histone deacetylases. |
2013 |
Genet. Mol. Res. |
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DNA methylation pyrosequencing assay is applicable for the assessment of epigenetic active environmental or clinical relevant chemicals. |
2013 |
Biomed Res Int |
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Up-regulation of miR-182 expression after epigenetic modulation of human melanoma cells. |
2013 |
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Combined histone deacetylase and cyclooxygenase inhibition achieves enhanced antiangiogenic effects in lung cancer cells. |
2013 |
Mol. Carcinog. |
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Histone deacetylase inhibitor reduces hypertrophic scarring in a rabbit ear model. |
2013 |
Plast. Reconstr. Surg. |
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Trichostatin-A modulates claudin-1 mRNA stability through the modulation of Hu antigen R and tristetraprolin in colon cancer cells. |
2013 |
Carcinogenesis |
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Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer. |
2013 |
Mol. Cancer |
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Effect of dynamic DNA methylation and histone acetylation on cPouV expression in differentiation of chick embryonic germ cells. |
2013 |
Stem Cells Dev. |
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Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters. |
2013 |
PLoS ONE |
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Increased alternative lengthening of telomere phenotypes of telomerase-negative immortal cells upon trichostatin--a treatment. |
2013 |
Anticancer Res. |
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Epigenetic silencing of the proapoptotic gene BIM in anaplastic large cell lymphoma through an MeCP2/SIN3a deacetylating complex. |
2013 |
Neoplasia |
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HDAC inhibitor confers radiosensitivity to prostate stem-like cells. |
2013 |
Br. J. Cancer |
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The NR4A2 nuclear receptor is recruited to novel nuclear foci in response to UV irradiation and participates in nucleotide excision repair. |
2013 |
PLoS ONE |
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Hu X et al. |
Histone deacetylase inhibitor trichostatin A promotes the osteogenic differentiation of rat adipose-derived stem cells by altering the epigenetic modifications on Runx2 promoter in a BMP signaling-dependent manner. |
2013 |
Stem Cells Dev. |
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Expression loss and revivification of RhoB gene in ovary carcinoma carcinogenesis and development. |
2013 |
PLoS ONE |
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Incompatible effects of p53 and HDAC inhibition on p21 expression and cell cycle progression. |
2013 |
Cell Death Dis |
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Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer. |
2013 |
Mol. Cancer |
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PSG gene expression is up-regulated by lysine acetylation involving histone and nonhistone proteins. |
2013 |
PLoS ONE |
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Small chemical chromatin effectors alter secondary metabolite production in Aspergillus clavatus. |
2013 |
Toxins (Basel) |
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Kim TW et al. |
Nuclear-encoded mitochondrial MTO1 and MRPL41 are regulated in an opposite epigenetic mode based on estrogen receptor status in breast cancer. |
2013 |
BMC Cancer |
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Gene expression-based prediction of myeloma cell sensitivity to histone deacetylase inhibitors. |
2013 |
Br. J. Cancer |
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Curcumin enhances the anticancer effects of trichostatin a in breast cancer cells. |
2013 |
Mol. Carcinog. |
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Identification of genes specifically methylated in Epstein-Barr virus-associated gastric carcinomas. |
2013 |
Cancer Sci. |
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Effects of trichostatin A on histone acetylation and methylation characteristics in early porcine embryos after somatic cell nuclear transfer. |
2013 |
Anim. Sci. J. |
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Histone deacetylase inhibition by trichostatin A mitigates LPS induced TNFα and IL-10 production in human placental explants. |
2013 |
Placenta |
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Epigenetic switching by the metabolism-sensing factors in the generation of orexin neurons from mouse embryonic stem cells. |
2013 |
J. Biol. Chem. |
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EBV-transformed lymphoblastoid cell lines as vaccines against cancer testis antigen-positive tumors. |
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Cancer Immunol. Immunother. |
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Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells. |
2013 |
Biochem. Pharmacol. |
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Inhibition of DNA methyltransferases and histone deacetylases induces astrocytic differentiation of neural progenitors. |
2013 |
Stem Cell Res |
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Mapping the telomere integrated genome of human herpesvirus 6A and 6B. |
2013 |
Virology |
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Structural basis for the design and synthesis of selective HDAC inhibitors. |
2013 |
Bioorg. Med. Chem. |
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Effects of trichostatin A in a rat model of acute graft-versus-host disease after liver transplantation. |
2013 |
Transplantation |
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Inhibition of HDAC2 protects the retina from ischemic injury. |
2013 |
Invest. Ophthalmol. Vis. Sci. |
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Synergistic induction of miR-126 by hypoxia and HDAC inhibitors in cardiac myocytes. |
2013 |
Biochem. Biophys. Res. Commun. |
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The multidimensional perturbation value: a single metric to measure similarity and activity of treatments in high-throughput multidimensional screens. |
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J Biomol Screen |
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Evaluation of long-term transgene expression in piggyBac-modified human T lymphocytes. |
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Induction of apoptosis by Trichostatin A in human breast cancer cell lines: involvement of 15-Lox-1. |
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Tumour Biol. |
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Overcoming chemotherapy resistance of ovarian cancer cells by liposomal cisplatin: molecular mechanisms unveiled by gene expression profiling. |
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Biochem. Pharmacol. |
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Histone deacetylase induces accelerated maturation in Xenopus laevis oocytes. |
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Dev. Growth Differ. |
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Improvement of porcine cloning efficiency by trichostain A through early-stage induction of embryo apoptosis. |
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Theriogenology |
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Histone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and efflux. |
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PLoS ONE |
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Histone deacetylase inhibitor Trichostatin A induces neural tube defects and promotes neural crest specification in the chicken neural tube. |
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Differentiation |
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2013 |
Cell Oncol (Dordr) |
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