Bai L and Merchant JL |
ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17560543
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Rigamonti D et al. |
Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators. |
2007 |
J. Biol. Chem. |
pmid:17565993
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Changes in histone acetylation during postovulatory aging of mouse oocyte. |
2007 |
Biol. Reprod. |
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Design, synthesis, and evaluation of isoindolinone-hydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors. |
2007 |
Bioorg. Med. Chem. Lett. |
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Protein kinase C-alpha antagonizes apoptosis induction by histone deacetylase inhibitors in multidrug resistant leukaemia cells. |
2007 |
Int. J. Biochem. Cell Biol. |
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Trichostatin A, a critical factor in maintaining the functional differentiation of primary cultured rat hepatocytes. |
2007 |
Toxicol. Appl. Pharmacol. |
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Histone acetylation and subcellular localization of chromosomal protein BRD4 during mouse oocyte meiosis and mitosis. |
2007 |
Mol. Hum. Reprod. |
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Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. |
2007 |
Mol. Cell. Biol. |
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Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation. |
2007 |
Nat. Med. |
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Liu L and Clipstone NA |
Prostaglandin F2alpha inhibits adipocyte differentiation via a G alpha q-calcium-calcineurin-dependent signaling pathway. |
2007 |
J. Cell. Biochem. |
pmid:16888802
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Loudni L et al. |
Design, synthesis and biological evaluation of 1,4-benzodiazepine-2,5-dione-based HDAC inhibitors. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17624773
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Kato N et al. |
Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells. |
2007 |
Leukemia |
pmid:17625602
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Bu Y and Gelman IH |
v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex. |
2007 |
J. Biol. Chem. |
pmid:17626016
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Dombrowsky H and Uhlig S |
Steroids and histone deacetylase in ventilation-induced gene transcription. |
2007 |
Eur. Respir. J. |
pmid:17626110
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Zampetaki A et al. |
Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-alpha is rescued by HDAC inhibitor trichostatin A. |
2007 |
Am. J. Physiol., Cell Physiol. |
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Strobl JS et al. |
Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro. |
2007 |
J. Parasitol. |
pmid:17626366
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Acetylation of histone H3 and adrenergic-regulated gene transcription in rat pinealocytes. |
2007 |
Endocrinology |
pmid:17628002
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Gahr S et al. |
The combination of the histone-deacetylase inhibitor trichostatin A and gemcitabine induces inhibition of proliferation and increased apoptosis in pancreatic carcinoma cells. |
2007 |
Int. J. Oncol. |
pmid:17671683
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Epigenetic regulation of CD20 protein expression in a novel B-cell lymphoma cell line, RRBL1, established from a patient treated repeatedly with rituximab-containing chemotherapy. |
2007 |
Int. J. Hematol. |
pmid:17675267
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Wang J et al. |
Histone deacetylase inhibitors suppress TF-kappaB-dependent agonist-driven tissue factor expression in endothelial cells and monocytes. |
2007 |
J. Biol. Chem. |
pmid:17675290
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Boric acid inhibits embryonic histone deacetylases: a suggested mechanism to explain boric acid-related teratogenicity. |
2007 |
Toxicol. Appl. Pharmacol. |
pmid:17320131
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FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism. |
2007 |
Br. J. Pharmacol. |
pmid:17325654
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Hishiki T et al. |
BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3. |
2007 |
J. Biol. Chem. |
pmid:17644518
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Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis. |
2007 |
Arthritis Rheum. |
pmid:17665426
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Ishihara K et al. |
Differentiation of eosinophilic leukemia EoL-1 cells into eosinophils induced by histone deacetylase inhibitors. |
2007 |
Life Sci. |
pmid:17258775
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Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity. |
2007 |
Neuron |
pmid:17329213
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Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma. |
2007 |
Neuro-oncology |
pmid:17329407
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Pan L et al. |
Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression. |
2007 |
Cancer |
pmid:17330857
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Robertson DM et al. |
Insulin-like Growth Factor Binding Protein-3 expression in the human corneal epithelium. |
2007 |
Exp. Eye Res. |
pmid:17709104
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Chen WY et al. |
Histone deacetylase inhibitors reduce steroidogenesis through SCF-mediated ubiquitination and degradation of steroidogenic factor 1 (NR5A1). |
2007 |
Mol. Cell. Biol. |
pmid:17709382
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Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes. |
2007 |
Mol. Cell. Biol. |
pmid:17709385
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Suppression of lipopolysaccharide- and tumour necrosis factor-alpha-induced interleukin (IL)-8 expression by glucocorticoids involves changes in IL-8 promoter acetylation. |
2007 |
Clin. Exp. Immunol. |
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Markova NG et al. |
Inhibition of histone deacetylation promotes abnormal epidermal differentiation and specifically suppresses the expression of the late differentiation marker profilaggrin. |
2007 |
J. Invest. Dermatol. |
pmid:17195011
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Histone deacetylase inhibitors preferentially augment transient transgene expression in human dermal fibroblasts. |
2007 |
Br. J. Dermatol. |
pmid:17711521
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Fujita Y et al. |
Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. |
2007 |
Dev. Cell |
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HDAC inhibitors TSA and sodium butyrate enhanced the human IL-5 expression by altering histone acetylation status at its promoter region. |
2007 |
Immunol. Lett. |
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Effect of histone deacetylase inhibitor trichostatin A (TSA) on the microtubular system of Tetrahymena. |
2007 |
Acta. Biol. Hung. |
pmid:18277464
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[Role of human telomerase reverse transcriptase in apoptosis of human umbilical vein endothelial cells induced by trichostatin A]. |
2007 |
Zhonghua Zhong Liu Za Zhi |
pmid:17892126
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Downregulation of microRNAs-143 and -145 in B-cell malignancies. |
2007 |
Cancer Sci. |
pmid:17892514
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Global chromatin compaction limits the strength of the DNA damage response. |
2007 |
J. Cell Biol. |
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The histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes. |
2007 |
Biochim. Biophys. Acta |
pmid:17894944
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Oshima M et al. |
Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17949687
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Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. |
2007 |
J. Med. Chem. |
pmid:17929798
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A proteomic analysis of protein variations during differentiation of v-myb-transformed monoblasts. |
2007 |
Leuk. Res. |
pmid:16930693
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Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression. |
2007 |
Exp. Hematol. |
pmid:17258075
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Hummel M et al. |
Transcriptional reactivation of murine cytomegalovirus ie gene expression by 5-aza-2'-deoxycytidine and trichostatin A in latently infected cells despite lack of methylation of the major immediate-early promoter. |
2007 |
J. Gen. Virol. |
pmid:17374752
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Appanah R et al. |
An unmethylated 3' promoter-proximal region is required for efficient transcription initiation. |
2007 |
PLoS Genet. |
pmid:17305432
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Epigenetic alteration of the donor cells does not recapitulate the reprogramming of DNA methylation in cloned embryos. |
2007 |
Reproduction |
pmid:18042635
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Bui HT et al. |
Regulation of chromatin and chromosome morphology by histone H3 modifications in pig oocytes. |
2007 |
Reproduction |
pmid:17307905
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Hattori N et al. |
Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells. |
2007 |
Genes Cells |
pmid:17352742
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Kwon HS et al. |
Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression. |
2006 Mar-Apr |
Biochim. Biophys. Acta |
pmid:16757381
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Mukhopadhyay NK et al. |
Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer. |
2006 |
Ann. Thorac. Surg. |
pmid:16488717
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Swanson S |
Invited commentary. |
2006 |
Ann. Thorac. Surg. |
pmid:16488718
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Song YF et al. |
High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma. |
2006 |
J. Clin. Pathol. |
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Rokhlin OW et al. |
Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells. |
2006 |
Mol. Cancer Res. |
pmid:16513842
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Activities of maturation-promoting factor (MPF) and mitogen-activated protein kinase (MAPK) are not required for the global histone deacetylation observed after germinal vesicle breakdown (GVBD) in porcine oocytes. |
2006 |
Reproduction |
pmid:16514187
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Sah NK et al. |
Effect of downregulation of survivin expression on radiosensitivity of human epidermoid carcinoma cells. |
2006 |
Int. J. Radiat. Oncol. Biol. Phys. |
pmid:17011457
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Kumar KS et al. |
Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells. |
2006 |
Oncol. Rep. |
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Alao JP et al. |
Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells. |
2006 |
Mol. Cancer |
pmid:17018141
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Kishigami S et al. |
Epigenetic abnormalities of the mouse paternal zygotic genome associated with microinsemination of round spermatids. |
2006 |
Dev. Biol. |
pmid:16325170
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Mogal A and Abdulkadir SA |
Effects of Histone Deacetylase Inhibitor (HDACi); Trichostatin-A (TSA) on the expression of housekeeping genes. |
2006 |
Mol. Cell. Probes |
pmid:16326072
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Gan Y et al. |
Dual effects of histone deacetylase inhibition by trichostatin A on endothelial nitric oxide synthase expression in endothelial cells. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16338217
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Nishiyama A et al. |
Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatin. |
2006 |
Mol. Biol. Cell |
pmid:16339075
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Trapp J et al. |
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. |
2006 |
J. Med. Chem. |
pmid:17149860
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Solomon JM et al. |
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. |
2006 |
Mol. Cell. Biol. |
pmid:16354677
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Kishigami S et al. |
Significant improvement of mouse cloning technique by treatment with trichostatin A after somatic nuclear transfer. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16356478
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Baradari V et al. |
Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells. |
2006 |
Endocr. Relat. Cancer |
pmid:17158768
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Taghiyev AF et al. |
TSA-induced cell death in prostate cancer cell lines is caspase-2 dependent and involves the PIDDosome. |
2006 |
Cancer Biol. Ther. |
pmid:17110788
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Hishikawa K and Fujita T |
[Basic research for renal regeneration]. |
2006 |
Nippon Rinsho |
pmid:16895225
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Meisel A et al. |
Inhibition of histone deacetylation protects wild-type but not gelsolin-deficient neurons from oxygen/glucose deprivation. |
2006 |
J. Neurochem. |
pmid:16895577
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Krishnan M et al. |
Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. |
2006 |
FASEB J. |
pmid:16246867
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Pampalakis G and Sotiropoulou G |
Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer. |
2006 |
Biol. Chem. |
pmid:16800739
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Wang Y et al. |
Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts. |
2006 |
Arthritis Rheum. |
pmid:16802366
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Morinobu A et al. |
Trichostatin A cooperates with Fas-mediated signal to induce apoptosis in rheumatoid arthritis synovial fibroblasts. |
2006 |
J. Rheumatol. |
pmid:16755652
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Son YO et al. |
Involvement of caspase activation and mitochondrial stress in trichostatin A-induced apoptosis of Burkitt's lymphoma cell line, Akata. |
2006 |
J. Cell. Biochem. |
pmid:16817225
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Lau QC et al. |
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. |
2006 |
Cancer Res. |
pmid:16818622
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Peng C et al. |
The transcriptional regulation role of BRD7 by binding to acetylated histone through bromodomain. |
2006 |
J. Cell. Biochem. |
pmid:16265664
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Foltz G et al. |
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. |
2006 |
Cancer Res. |
pmid:16818640
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Mori T et al. |
Estrogen receptor-alpha methylation predicts melanoma progression. |
2006 |
Cancer Res. |
pmid:16818643
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Sato K et al. |
Deficient expression of the DPD gene is caused by epigenetic modification in biliary tract cancer cells, and induces high sensitivity to 5-FU treatment. |
2006 |
Int. J. Oncol. |
pmid:16820886
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Qi H and Ratnam M |
Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. |
2006 |
Cancer Res. |
pmid:16740727
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Nusinzon I and Horvath CM |
Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation. |
2006 |
Mol. Cell. Biol. |
pmid:16581785
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Ibanez de Caceres I et al. |
Identification of novel target genes by an epigenetic reactivation screen of renal cancer. |
2006 |
Cancer Res. |
pmid:16707423
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Imre G et al. |
Histone deacetylase inhibitors suppress the inducibility of nuclear factor-kappaB by tumor necrosis factor-alpha receptor-1 down-regulation. |
2006 |
Cancer Res. |
pmid:16707469
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Jaalouk DE et al. |
Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors. |
2006 |
Virol. J. |
pmid:16603064
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Lu Z et al. |
E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer. |
2006 |
Oncogene |
pmid:16158053
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Hwang DY and Ismail-Beigi F |
Control of Glut1 promoter activity under basal conditions and in response to hyperosmolarity: role of Sp1. |
2006 |
Am. J. Physiol., Cell Physiol. |
pmid:16162661
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Kim MY et al. |
Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. |
2006 |
Mol. Endocrinol. |
pmid:16497729
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Leng Y and Chuang DM |
Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. |
2006 |
J. Neurosci. |
pmid:16837598
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Aung HT et al. |
LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression. |
2006 |
FASEB J. |
pmid:16816106
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Hong ZY et al. |
[Mechanism of apoptosis induced by trichostatin A in leukemia Molt-4 cells analyzed by microarray]. |
2006 |
Ai Zheng |
pmid:16965673
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Banwell CM et al. |
Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. |
2006 |
Clin. Cancer Res. |
pmid:16609009
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Kim TY et al. |
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. |
2006 |
Cancer Res. |
pmid:16885346
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Kimura N et al. |
Alteration of developmental program in Paramecium by treatment with trichostatin a: a possible involvement of histone modification. |
2006 |
Protist |
pmid:16839811
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Monte M et al. |
MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16847267
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Zaveri NT et al. |
Regulation of the prepronociceptin gene and its effect on neuronal differentiation. |
2006 |
Gene |
pmid:16935438
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Dokras A et al. |
Epigenetic regulation of maspin expression in the human placenta. |
2006 |
Mol. Hum. Reprod. |
pmid:16936308
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Yamamura K et al. |
Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis. |
2006 |
Br. J. Haematol. |
pmid:16939493
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Das PM et al. |
Methylation mediated silencing of TMS1/ASC gene in prostate cancer. |
2006 |
Mol. Cancer |
pmid:16848908
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Puppin C et al. |
HEX expression and localization in normal mammary gland and breast carcinoma. |
2006 |
BMC Cancer |
pmid:16854221
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