Amin HM et al. |
Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). |
2001 |
Br. J. Haematol. |
pmid:11703323
|
Pile LA et al. |
The histone deacetylase inhibitor trichostatin A influences the development of Drosophila melanogaster. |
2001 |
Cell. Mol. Life Sci. |
pmid:11706997
|
Sachs LM et al. |
An essential role of histone deacetylases in postembryonic organ transformations in Xenopus laevis. |
2001 |
Int. J. Mol. Med. |
pmid:11712071
|
Lefevre P et al. |
Identification of factors mediating the developmental regulation of the early acting -3.9 kb chicken lysozyme enhancer element. |
2001 |
Nucleic Acids Res. |
pmid:11713304
|
Sekita N et al. |
Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines. |
2001 |
Jpn. J. Cancer Res. |
pmid:11572762
|
Jorgensen JS and Nilson JH |
AR suppresses transcription of the alpha glycoprotein hormone subunit gene through protein-protein interactions with cJun and activation transcription factor 2. |
2001 |
Mol. Endocrinol. |
pmid:11518798
|
Phiel CJ et al. |
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. |
2001 |
J. Biol. Chem. |
pmid:11473107
|
Sundqvist A et al. |
Functional knockout of the corepressor CtBP by the second exon of adenovirus E1a relieves repression of transcription. |
2001 |
Exp. Cell Res. |
pmid:11478854
|
Jacob AL et al. |
Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5. |
2001 |
J. Biol. Chem. |
pmid:11479297
|
Benjamin D and Jost JP |
Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation. |
2001 |
Nucleic Acids Res. |
pmid:11522830
|
Li J et al. |
Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. |
2001 |
Mol. Cell. Biol. |
pmid:11689710
|
Hirschler-Laszkiewicz I et al. |
The role of acetylation in rDNA transcription. |
2001 |
Nucleic Acids Res. |
pmid:11600700
|
Rashid SF et al. |
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. |
2001 |
Oncogene |
pmid:11313934
|
Wang H et al. |
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. |
2001 |
Science |
pmid:11387442
|
Klar AJ et al. |
A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans. |
2001 |
Genetics |
pmid:11404352
|
Massa S et al. |
3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. |
2001 |
J. Med. Chem. |
pmid:11405644
|
Setlow JK et al. |
Evidence for gene silencing in Haemophilus influenzae. |
2001 |
Mutat. Res. |
pmid:11406170
|
Singal R et al. |
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. |
2001 |
Cancer Res. |
pmid:11406558
|
Baur JA et al. |
Telomere position effect in human cells. |
2001 |
Science |
pmid:11408657
|
Zelivianski S et al. |
Multipathways for transdifferentiation of human prostate cancer cells into neuroendocrine-like phenotype. |
2001 |
Biochim. Biophys. Acta |
pmid:11389966
|
Harada Y et al. |
A hematopoietic-specific transmembrane protein, Art-1, is possibly regulated by AML1. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11396961
|
Arthur JL et al. |
Herpes simplex virus type 1 promoter activity during latency establishment, maintenance, and reactivation in primary dorsal root neurons in vitro. |
2001 |
J. Virol. |
pmid:11264377
|
Wu JT et al. |
Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:11171632
|
Taddei A et al. |
Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases. |
2001 |
Nat. Cell Biol. |
pmid:11175742
|
Ferrara FF et al. |
Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. |
2001 |
Cancer Res. |
pmid:11196162
|
Furumai R et al. |
Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11134513
|
Johnson CA et al. |
Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. |
2001 |
J. Biol. Chem. |
pmid:11136718
|
Griswold MD et al. |
Mechanisms involved in the homologous down-regulation of transcription of the follicle-stimulating hormone receptor gene in Sertoli cells. |
2001 |
Mol. Cell. Endocrinol. |
pmid:11223181
|
He LZ et al. |
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. |
2001 |
J. Clin. Invest. |
pmid:11696577
|
Rombouts K et al. |
Trichostatin A, lead compound for development of antifibrogenic drugs. |
2001 Jul-Sep |
Acta Gastroenterol. Belg. |
pmid:11680040
|
McGuinness MC et al. |
Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. |
2001 Sep-Oct |
Mol. Genet. Metab. |
pmid:11592822
|
López-Solache I et al. |
Regulation of uncoupling protein-2 mRNA in L6 myotubules: II: Thyroid hormone amplifies stimulation of uncoupling protein-2 gene by thiazolidinediones and other peroxisome proliferator-activated receptor ligands in L6 myotubules: evidence for a priming effect. |
2002 |
Endocrine |
pmid:12588052
|
Stimson KM and Vertino PM |
Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture. |
2002 |
J. Biol. Chem. |
pmid:11733524
|
Guo WH et al. |
Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor. |
2002 |
Oncogene |
pmid:12447699
|
Marin-Husstege M et al. |
Histone deacetylase activity is necessary for oligodendrocyte lineage progression. |
2002 |
J. Neurosci. |
pmid:12451133
|
Wang ZM et al. |
Trichostatin A inhibits proliferation and induces expression of p21WAF and p27 in human brain tumor cell lines. |
2002 |
Ai Zheng |
pmid:12508652
|
Duharcourt S and Yao MC |
Role of histone deacetylation in developmentally programmed DNA rearrangements in Tetrahymena thermophila. |
2002 |
Eukaryotic Cell |
pmid:12455963
|
Strait KA et al. |
Cell cycle blockade and differentiation of ovarian cancer cells by the histone deacetylase inhibitor trichostatin A are associated with changes in p21, Rb, and Id proteins. |
2002 |
Mol. Cancer Ther. |
pmid:12479699
|
Blagosklonny MV et al. |
Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity. |
2002 |
Mol. Cancer Ther. |
pmid:12481415
|
Kim JY et al. |
Probing lysine acetylation with a modification-specific marker ion using high-performance liquid chromatography/electrospray-mass spectrometry with collision-induced dissociation. |
2002 |
Anal. Chem. |
pmid:12433071
|
Elaut G et al. |
Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes. |
2002 |
Drug Metab. Dispos. |
pmid:12433798
|
Yáñez RJ and Porter AC |
A chromosomal position effect on gene targeting in human cells. |
2002 |
Nucleic Acids Res. |
pmid:12433992
|
Wilson MA et al. |
The histone deacetylase inhibitor trichostatin A blocks progesterone receptor-mediated transactivation of the mouse mammary tumor virus promoter in vivo. |
2002 |
J. Biol. Chem. |
pmid:11821430
|
Takechi S et al. |
Chicken HDAC2 down-regulates IgM light chain gene promoter activity. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12437980
|
Deroanne CF et al. |
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling. |
2002 |
Oncogene |
pmid:11821955
|
Ego T et al. |
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression. |
2002 |
Oncogene |
pmid:12370815
|
Zhang W and Kone BC |
NF-kappaB inhibits transcription of the H(+)-K(+)-ATPase alpha(2)-subunit gene: role of histone deacetylases. |
2002 |
Am. J. Physiol. Renal Physiol. |
pmid:12372765
|
Handumrongkul C et al. |
Distinct sets of cellular genes control the expression of transfected, nuclear-localized genes. |
2002 |
Mol. Ther. |
pmid:11829526
|
Ailenberg M and Silverman M |
Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12379227
|
Herold C et al. |
The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells. |
2002 |
J. Hepatol. |
pmid:11830335
|
Zhou DC et al. |
Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo. |
2002 |
Blood |
pmid:11830487
|
Valapour M et al. |
Histone deacetylation inhibits IL4 gene expression in T cells. |
2002 |
J. Allergy Clin. Immunol. |
pmid:11842291
|
McBurney MW et al. |
Evidence for repeat-induced gene silencing in cultured Mammalian cells: inactivation of tandem repeats of transfected genes. |
2002 |
Exp. Cell Res. |
pmid:11855851
|
Hou M et al. |
The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells. |
2002 |
Exp. Cell Res. |
pmid:11855854
|
Remiszewski SW et al. |
Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates. |
2002 |
J. Med. Chem. |
pmid:11831887
|
Kiefer SM et al. |
Murine Sall1 represses transcription by recruiting a histone deacetylase complex. |
2002 |
J. Biol. Chem. |
pmid:11836251
|
Roddie PH et al. |
Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1. |
2002 |
Leukemia |
pmid:11840267
|
Taniura S et al. |
Transcriptional regulation of cyclooxygenase-1 by histone deacetylase inhibitors in normal human astrocyte cells. |
2002 |
J. Biol. Chem. |
pmid:11877441
|
Heltweg B and Jung M |
A microplate reader-based nonisotopic histone deacetylase activity assay. |
2002 |
Anal. Biochem. |
pmid:11878795
|
Kamitani H et al. |
Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced. |
2002 |
Neuro-oncology |
pmid:11916500
|
Kishikawa S et al. |
Roles of histone acetylation in the Dnmt1 gene expression. |
2002 |
Nucleic Acids Res. Suppl. |
pmid:12903179
|
Rombouts K et al. |
Trichostatin A, a histone deacetylase inhibitor, suppresses collagen synthesis and prevents TGF-beta(1)-induced fibrogenesis in skin fibroblasts. |
2002 |
Exp. Cell Res. |
pmid:12169274
|
Waterborg JH and Kapros T |
Kinetic analysis of histone acetylation turnover and Trichostatin A induced hyper- and hypoacetylation in alfalfa. |
2002 |
Biochem. Cell Biol. |
pmid:12123281
|
Mikkelsen IM et al. |
Activation of the gamma-glutamyltransferase promoter 2 in the rat colon carcinoma cell line CC531 by histone deacetylase inhibitors is mediated through the Sp1 binding motif. |
2002 |
Biochem. Pharmacol. |
pmid:12123752
|
Petti MC et al. |
Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies. |
2002 |
Blood |
pmid:12130525
|
Avram D et al. |
COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein. |
2002 |
Biochem. J. |
pmid:12196208
|
Guo Y et al. |
Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion. |
2002 |
J. Biol. Chem. |
pmid:12198113
|
Wittich S et al. |
Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells. |
2002 |
J. Med. Chem. |
pmid:12109913
|
Toyooka S et al. |
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures. |
2002 |
Clin. Cancer Res. |
pmid:12114433
|
Choi HS et al. |
Trichostatin A, a histone deacetylase inhibitor, activates the IGFBP-3 promoter by upregulating Sp1 activity in hepatoma cells: alteration of the Sp1/Sp3/HDAC1 multiprotein complex. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12200149
|
Maecker HL et al. |
Epigenetic changes in tumor Fas levels determine immune escape and response to therapy. |
2002 |
Cancer Cell |
pmid:12204534
|
Fang D et al. |
Selective down-regulation of tyrosinase family gene TYRP1 by inhibition of the activity of melanocyte transcription factor, MITF. |
2002 |
Nucleic Acids Res. |
pmid:12136092
|
Zschocke J et al. |
Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells. |
2002 |
J. Biol. Chem. |
pmid:12138116
|
Yu Z et al. |
Histone deacetylases augment cytokine induction of the iNOS gene. |
2002 |
J. Am. Soc. Nephrol. |
pmid:12138131
|
Li J et al. |
Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. |
2002 |
Mol. Cell. Biol. |
pmid:12138181
|
Aapola U et al. |
Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity. |
2002 |
Nucleic Acids Res. |
pmid:12177302
|
Chang TH and Szabo E |
Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. |
2002 |
Clin. Cancer Res. |
pmid:11948134
|
Nair RR et al. |
Enhancement of transgene expression by combining glucocorticoids and anti-mitotic agents during transient transfection using DNA-cationic liposomes. |
2002 |
Mol. Ther. |
pmid:11945073
|
Qiu P and Li L |
Histone acetylation and recruitment of serum responsive factor and CREB-binding protein onto SM22 promoter during SM22 gene expression. |
2002 |
Circ. Res. |
pmid:11988486
|
Mai A et al. |
Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation. |
2002 |
J. Med. Chem. |
pmid:11960489
|
Merezak C et al. |
Inhibition of histone deacetylases induces bovine leukemia virus expression in vitro and in vivo. |
2002 |
J. Virol. |
pmid:11967319
|
Weston AD et al. |
Requirement for RAR-mediated gene repression in skeletal progenitor differentiation. |
2002 |
J. Cell Biol. |
pmid:12105181
|
Toyooka S et al. |
Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. |
2002 |
Oncogene |
pmid:12082623
|
Maehara K et al. |
Effects of histone acetylation on transcriptional regulation of manganese superoxide dismutase gene. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12083788
|
Iezzi S et al. |
Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12032356
|
Nielsen J |
Combinatorial synthesis of natural products. |
2002 |
Curr Opin Chem Biol |
pmid:12023109
|
Mikkelsen IM et al. |
The expression of gamma-glutamyltransferase in rat colon carcinoma cells is distinctly regulated during differentiation and oxidative stress. |
2002 |
Mol. Cell. Biochem. |
pmid:12030384
|
Bharadwaj S and Prasad GL |
Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. |
2002 |
Cancer Lett. |
pmid:12065096
|
Ito K et al. |
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12070353
|
Katula KS et al. |
Cell cycle specific changes in the human cyclin B1 gene regulatory region as revealed by response to trichostatin A. |
2002 |
Arch. Biochem. Biophys. |
pmid:12054478
|
Wang XQ et al. |
Histone deacetylase inhibition results in decreased macrophage CD9 expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12056820
|
Rahmani M et al. |
The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process. |
2002 |
Exp. Cell Res. |
pmid:12061815
|
Woo SH et al. |
Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors. |
2002 |
J. Med. Chem. |
pmid:12061890
|
Chen Y et al. |
On the epigenetic regulation of the human reelin promoter. |
2002 |
Nucleic Acids Res. |
pmid:12087179
|
Travers H et al. |
Human CD34+ hematopoietic progenitor cells hyperacetylate core histones in response to sodium butyrate, but not trichostatin A. |
2002 |
Exp. Cell Res. |
pmid:12413881
|
Wilson AJ et al. |
Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention. |
2002 |
Cancer Res. |
pmid:12414619
|
Choy JS and Kron SJ |
NuA4 subunit Yng2 function in intra-S-phase DNA damage response. |
2002 |
Mol. Cell. Biol. |
pmid:12417725
|
Ghoshal K et al. |
Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. |
2002 |
Mol. Cell. Biol. |
pmid:12417732
|
Hauser C et al. |
Activation of the mouse histone deacetylase 1 gene by cooperative histone phosphorylation and acetylation. |
2002 |
Mol. Cell. Biol. |
pmid:12391151
|
Westendorf JJ et al. |
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. |
2002 |
Mol. Cell. Biol. |
pmid:12391164
|