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2008 |
Oncogene |
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2008 |
Exp. Mol. Pathol. |
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Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. |
2008 |
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2008 |
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The effect of histone deacetylase inhibitor trichostatin A (TSA) on the incorporation of 32P (Pi) and 3H-palmitic acid into the phospholipids of Tetrahymena. |
2008 Jan-Feb |
Cell Biochem. Funct. |
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Smetana K et al. |
To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A. |
2008 Jul-Sep |
Eur J Histochem |
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In vivo application of histone deacetylase inhibitor trichostatin-a impairs murine male meiosis. |
2008 Mar-Apr |
J. Androl. |
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Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9. |
2008 May-Jun |
Jpn. J. Ophthalmol. |
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[NF-kappaB modulates activation of the BMP-2 gene by trichostatin A]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
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[Nucleosome positioning within neomycinphosphotransferase gene (NPTII) on yeast plasmid in repressed and active state]. |
2008 Nov-Dec |
Mol. Biol. (Mosk.) |
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Short-chain fatty acids and trichostatin A alter tight junction permeability in human umbilical vein endothelial cells. |
2008 Nov-Dec |
Nutrition |
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Regulatory roles for histone deacetylation in IL-1beta-induced nitric oxide release in pancreatic beta-cells. |
2008 Sep-Oct |
J. Cell. Mol. Med. |
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Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661W cells and the retina. |
2009 |
J. Neurosci. Res. |
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Upregulation of human with-no-lysine kinase-4 gene expression by GATA-1 acetylation. |
2009 |
Int. J. Biochem. Cell Biol. |
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JBIR-17, a novel trichostatin analog from Streptomyces sp. 26634. |
2009 |
J. Antibiot. |
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The anticancer effect of histone deacetylase inhibitors and combination with the cytotoxic agents in lung cancer cells: biological analyses for future clinical application. |
2009 |
J Nippon Med Sch |
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Endothelin-stimulated human B-type natriuretic peptide gene expression is mediated by Yin Yang 1 in association with histone deacetylase 2. |
2009 |
Hypertension |
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Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs. |
2009 |
Clin. Cancer Res. |
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Evaluation of in vitro cultured rat oocytes, from different strains, by spindle morphology and maturation-promoting-factor activity combined with nuclear-transfer experiments. |
2009 |
Cloning Stem Cells |
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Wang X et al. |
Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin-modifying agents. |
2009 |
Cancer Res. |
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Hirata H et al. |
Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways. |
2009 |
Clin. Cancer Res. |
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Up-regulation of GADD45alpha expression by NSAIDs leads to apoptotic and necrotic colon cancer cell deaths. |
2009 |
Apoptosis |
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Anti-leukemia activity of MS-275 histone deacetylase inhibitor implicates 4-1BBL/4-1BB immunomodulatory functions. |
2009 |
PLoS ONE |
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Cytochalasin B and trichostatin a treatment postactivation improves in vitro development of porcine somatic cell nuclear transfer embryos. |
2009 |
Cloning Stem Cells |
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Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic alpha3beta-tetrapeptides. |
2009 |
J. Med. Chem. |
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Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy. |
2009 |
J. Mol. Cell. Cardiol. |
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Inhibition of histone deacetylase causes reduction of appressorium formation in the rice blast fungus Magnaporthe oryzae. |
2009 |
J. Gen. Appl. Microbiol. |
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Acetylation level of histone H3 in early embryonic stages affects subsequent development of miniature pig somatic cell nuclear transfer embryos. |
2009 |
J. Reprod. Dev. |
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Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives. |
2009 |
Bioorg. Med. Chem. |
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Gao J et al. |
Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site. |
2009 |
Glia |
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An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner. |
2009 |
Biochem. Biophys. Res. Commun. |
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HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells. |
2009 |
J. Mol. Cell. Cardiol. |
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2009 |
Biochem. Biophys. Res. Commun. |
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Timing is everything: order of administration of 5-aza 2' deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity. |
2009 |
Cancer Lett. |
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Suppression of caspase-11 expression by histone deacetylase inhibitors. |
2009 |
Biochem. Biophys. Res. Commun. |
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Promoter CpG methylation in cancer cells contributes to the regulation of MUC4. |
2009 |
Br. J. Cancer |
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2009 |
Methods Mol. Biol. |
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2009 |
J. Mol. Cell. Cardiol. |
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Trichostatin A enhances OGD-astrocyte viability by inhibiting inflammatory reaction mediated by NF-kappaB. |
2009 |
Brain Res. Bull. |
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Identification of two independent SUMO-interacting motifs in Daxx: evolutionary conservation from Drosophila to humans and their biochemical functions. |
2009 |
Cell Cycle |
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HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling. |
2009 |
J. Biol. Chem. |
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Dynamic histone variant exchange accompanies gene induction in T cells. |
2009 |
Mol. Cell. Biol. |
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Inhibition of p27Kip1 gene transcription by mitogens. |
2009 |
Cell Cycle |
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Inhibition of histone deacetylases antagonized FGF2 and IL-1beta effects on MMP expression in human articular chondrocytes. |
2009 |
Growth Factors |
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Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
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J. Med. Chem. |
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Novel HDAC6 isoform selective chiral small molecule histone deacetylase inhibitors. |
2009 |
Bioorg. Med. Chem. Lett. |
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Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL. |
2009 |
Eur. J. Pharmacol. |
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Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2. |
2009 |
Mol. Cell Proteomics |
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Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas. |
2009 |
Lab. Invest. |
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Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice. |
2009 |
Curr Cancer Drug Targets |
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The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons. |
2009 |
J. Cell. Sci. |
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Trichostatin A with adenovirus-mediated p53 gene transfer synergistically induces apoptosis in breast cancer cell line MDA-MB-231. |
2009 |
Oncol. Rep. |
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MicroRNA-1 and MicroRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells. |
2009 |
Circ. J. |
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Interspecies somatic cell nucleus transfer with porcine oocytes as recipients: A novel bioassay system for assessing the competence of canine somatic cells to develop into embryos. |
2009 |
Theriogenology |
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Restoration of immune response gene induction in trophoblast tumor cells associated with cellular senescence. |
2009 |
J. Reprod. Immunol. |
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Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues. |
2009 |
Exp. Hematol. |
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Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer. |
2009 |
Oncogene |
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Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1. |
2009 |
J. Neurochem. |
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Anti-inflammatory effect of Trichostatin-A on murine bone marrow-derived macrophages. |
2009 |
Arch. Pharm. Res. |
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Structural and functional studies of the yeast class II Hda1 histone deacetylase complex. |
2009 |
J. Mol. Biol. |
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PTEN/AKT pathway involved in histone deacetylases inhibitor induced cell growth inhibition and apoptosis of oral squamous cell carcinoma cells. |
2009 |
Oral Oncol. |
pmid:19574087
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[Recent advances in DNA demethylation in tumor therapy]. |
2009 |
Zhonghua Bing Li Xue Za Zhi |
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Histone deacetylases regulate multicellular development in the social amoeba Dictyostelium discoideum. |
2009 |
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Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells. |
2009 |
Cancer Res. |
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Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury. |
2009 |
Am. J. Physiol. Renal Physiol. |
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Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes. |
2009 |
FASEB J. |
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MLH1 protects from resistance acquisition by the histone deacetylase inhibitor trichostatin A in colon tumor cells. |
2009 |
Int. J. Oncol. |
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[Role of histone deacetylase in inhibiting invasion of human gastric carcinoma cell line SGC-7901 by PPARgamma-mediated pathway]. |
2009 |
Ai Zheng |
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Microarray study of mechanism of trichostatin a inducing apoptosis of Molt-4 cells. |
2009 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
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Histone deacetylase inhibitor uses p21(Cip1) to maintain anergy in CD4+ T cells. |
2009 |
Int. Immunopharmacol. |
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Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation. |
2009 |
Biochem. Biophys. Res. Commun. |
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Co-treatment with deoxycholic acid and azoxymethane accelerates secretion of HMGB1 in IEC6 intestinal epithelial cells. |
2009 |
Cell Prolif. |
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Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy. |
2009 |
Am. J. Physiol. Renal Physiol. |
pmid:19640900
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Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts. |
2009 |
Anticancer Drugs |
pmid:19606018
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Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis. |
2009 |
Arthritis Rheum. |
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Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes. |
2009 |
Haematologica |
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Regulation of adipocyte differentiation by histone deacetylase inhibitors. |
2009 |
Arch. Pharm. Res. |
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ATF-2 regulates lipopolysaccharide-induced transcription in macrophage cells. |
2009 |
Biochem. Biophys. Res. Commun. |
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Trichostatin A sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by down-regulation of c-FLIPL via inhibition of EGFR pathway. |
2009 |
Biochem. Pharmacol. |
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Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells. |
2009 |
Arch. Med. Res. |
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HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: potential implications for the immunosurveillance of cancer. |
2009 |
Oncogene |
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Histone acetylation is recruited in consolidation as a molecular feature of stronger memories. |
2009 |
Learn. Mem. |
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HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer. |
2009 |
Mol. Endocrinol. |
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Zn(II)-dependent histone deacetylase inhibitors: suberoylanilide hydroxamic acid and trichostatin A. |
2009 |
Int. J. Biochem. Cell Biol. |
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2009 |
J. Cell Biol. |
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Induction of E-cadherin in lung cancer and interaction with growth suppression by histone deacetylase inhibition. |
2009 |
J Thorac Oncol |
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DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. |
2009 |
Gut |
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Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening. |
2009 |
PLoS ONE |
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Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A. |
2009 |
Arch. Toxicol. |
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Identification of trichostatin A as a novel transcriptional up-regulator of scavenger receptor BI both in HepG2 and RAW 264.7 cells. |
2009 |
Atherosclerosis |
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The Scar-in-a-Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well. |
2009 |
Br. J. Pharmacol. |
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Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma. |
2009 |
Genes Chromosomes Cancer |
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Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells. |
2009 |
Oncol. Rep. |
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High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth. |
2009 |
Clin. Cancer Res. |
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Screening of amide analogues of Trichostatin A in cultures of primary rat hepatocytes: search for potent and safe HDAC inhibitors. |
2009 |
Invest New Drugs |
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Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. |
2009 |
Cancer Lett. |
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Comparative epigenomics of human and mouse mammary tumors. |
2009 |
Genes Chromosomes Cancer |
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Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells. |
2009 |
Oncogene |
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The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells. |
2009 |
Cancer Gene Ther. |
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