Sanyal S et al. |
Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. |
2002 |
J. Biol. Chem. |
pmid:11705994
|
Galasinski SC et al. |
Global regulation of post-translational modifications on core histones. |
2002 |
J. Biol. Chem. |
pmid:11709551
|
Sawa H et al. |
Histone deacetylase inhibitors such as sodium butyrate and trichostatin A inhibit vascular endothelial growth factor (VEGF) secretion from human glioblastoma cells. |
2002 |
Brain Tumor Pathol |
pmid:12622137
|
Suzuki-Mizushima Y et al. |
Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells. |
2002 |
Brain Res. |
pmid:12270499
|
Boutillier AL et al. |
Constitutive repression of E2F1 transcriptional activity through HDAC proteins is essential for neuronal survival. |
2002 |
Ann. N. Y. Acad. Sci. |
pmid:12485907
|
Zarnegar R et al. |
Increasing the effectiveness of radioactive iodine therapy in the treatment of thyroid cancer using Trichostatin A, a histone deacetylase inhibitor. |
2002 |
Surgery |
pmid:12490845
|
Chen T et al. |
Histone acetylation is involved in hsp70 gene transcription regulation in Drosophila melanogaster. |
2002 |
Arch. Biochem. Biophys. |
pmid:12464268
|
Rombouts K et al. |
Actin filament formation, reorganization and migration are impaired in hepatic stellate cells under influence of trichostatin A, a histone deacetylase inhibitor. |
2002 |
J. Hepatol. |
pmid:12445420
|
Guo WH et al. |
Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor. |
2002 |
Oncogene |
pmid:12447699
|
Marin-Husstege M et al. |
Histone deacetylase activity is necessary for oligodendrocyte lineage progression. |
2002 |
J. Neurosci. |
pmid:12451133
|
Herold C et al. |
The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells. |
2002 |
J. Hepatol. |
pmid:11830335
|
Zhou DC et al. |
Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in vivo. |
2002 |
Blood |
pmid:11830487
|
Valapour M et al. |
Histone deacetylation inhibits IL4 gene expression in T cells. |
2002 |
J. Allergy Clin. Immunol. |
pmid:11842291
|
McBurney MW et al. |
Evidence for repeat-induced gene silencing in cultured Mammalian cells: inactivation of tandem repeats of transfected genes. |
2002 |
Exp. Cell Res. |
pmid:11855851
|
Hou M et al. |
The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells. |
2002 |
Exp. Cell Res. |
pmid:11855854
|
Remiszewski SW et al. |
Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates. |
2002 |
J. Med. Chem. |
pmid:11831887
|
Kiefer SM et al. |
Murine Sall1 represses transcription by recruiting a histone deacetylase complex. |
2002 |
J. Biol. Chem. |
pmid:11836251
|
Roddie PH et al. |
Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1. |
2002 |
Leukemia |
pmid:11840267
|
Taniura S et al. |
Transcriptional regulation of cyclooxygenase-1 by histone deacetylase inhibitors in normal human astrocyte cells. |
2002 |
J. Biol. Chem. |
pmid:11877441
|
Heltweg B and Jung M |
A microplate reader-based nonisotopic histone deacetylase activity assay. |
2002 |
Anal. Biochem. |
pmid:11878795
|
Kamitani H et al. |
Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced. |
2002 |
Neuro-oncology |
pmid:11916500
|
Kishikawa S et al. |
Roles of histone acetylation in the Dnmt1 gene expression. |
2002 |
Nucleic Acids Res. Suppl. |
pmid:12903179
|
Mikkelsen IM et al. |
Activation of the gamma-glutamyltransferase promoter 2 in the rat colon carcinoma cell line CC531 by histone deacetylase inhibitors is mediated through the Sp1 binding motif. |
2002 |
Biochem. Pharmacol. |
pmid:12123752
|
Petti MC et al. |
Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies. |
2002 |
Blood |
pmid:12130525
|
Avram D et al. |
COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein. |
2002 |
Biochem. J. |
pmid:12196208
|
Guo Y et al. |
Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion. |
2002 |
J. Biol. Chem. |
pmid:12198113
|
Wittich S et al. |
Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells. |
2002 |
J. Med. Chem. |
pmid:12109913
|
Toyooka S et al. |
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures. |
2002 |
Clin. Cancer Res. |
pmid:12114433
|
Choi HS et al. |
Trichostatin A, a histone deacetylase inhibitor, activates the IGFBP-3 promoter by upregulating Sp1 activity in hepatoma cells: alteration of the Sp1/Sp3/HDAC1 multiprotein complex. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12200149
|
Maecker HL et al. |
Epigenetic changes in tumor Fas levels determine immune escape and response to therapy. |
2002 |
Cancer Cell |
pmid:12204534
|
Fang D et al. |
Selective down-regulation of tyrosinase family gene TYRP1 by inhibition of the activity of melanocyte transcription factor, MITF. |
2002 |
Nucleic Acids Res. |
pmid:12136092
|
Zschocke J et al. |
Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells. |
2002 |
J. Biol. Chem. |
pmid:12138116
|
Yu Z et al. |
Histone deacetylases augment cytokine induction of the iNOS gene. |
2002 |
J. Am. Soc. Nephrol. |
pmid:12138131
|
Li J et al. |
Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. |
2002 |
Mol. Cell. Biol. |
pmid:12138181
|
Aapola U et al. |
Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity. |
2002 |
Nucleic Acids Res. |
pmid:12177302
|
Merezak C et al. |
Inhibition of histone deacetylases induces bovine leukemia virus expression in vitro and in vivo. |
2002 |
J. Virol. |
pmid:11967319
|
Weston AD et al. |
Requirement for RAR-mediated gene repression in skeletal progenitor differentiation. |
2002 |
J. Cell Biol. |
pmid:12105181
|
Toyooka S et al. |
Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells. |
2002 |
Oncogene |
pmid:12082623
|
Maehara K et al. |
Effects of histone acetylation on transcriptional regulation of manganese superoxide dismutase gene. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12083788
|
Iezzi S et al. |
Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12032356
|
Nielsen J |
Combinatorial synthesis of natural products. |
2002 |
Curr Opin Chem Biol |
pmid:12023109
|
Mikkelsen IM et al. |
The expression of gamma-glutamyltransferase in rat colon carcinoma cells is distinctly regulated during differentiation and oxidative stress. |
2002 |
Mol. Cell. Biochem. |
pmid:12030384
|
Bharadwaj S and Prasad GL |
Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. |
2002 |
Cancer Lett. |
pmid:12065096
|
Ito K et al. |
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12070353
|
Katula KS et al. |
Cell cycle specific changes in the human cyclin B1 gene regulatory region as revealed by response to trichostatin A. |
2002 |
Arch. Biochem. Biophys. |
pmid:12054478
|
Wang XQ et al. |
Histone deacetylase inhibition results in decreased macrophage CD9 expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12056820
|
Rahmani M et al. |
The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process. |
2002 |
Exp. Cell Res. |
pmid:12061815
|
Woo SH et al. |
Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors. |
2002 |
J. Med. Chem. |
pmid:12061890
|
Chen Y et al. |
On the epigenetic regulation of the human reelin promoter. |
2002 |
Nucleic Acids Res. |
pmid:12087179
|
Im H et al. |
Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain. |
2002 |
Biochemistry |
pmid:12484752
|
Gong XQ and Li L |
Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation. |
2002 |
J. Biol. Chem. |
pmid:11809751
|
Rössig L et al. |
Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis. |
2002 |
Circ. Res. |
pmid:12411399
|
Ghoshal K et al. |
Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure. |
2002 |
Mol. Cell. Biol. |
pmid:12417732
|
Hauser C et al. |
Activation of the mouse histone deacetylase 1 gene by cooperative histone phosphorylation and acetylation. |
2002 |
Mol. Cell. Biol. |
pmid:12391151
|
Westendorf JJ et al. |
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. |
2002 |
Mol. Cell. Biol. |
pmid:12391164
|
Sourlingas TG et al. |
The effect of the histone deacetylase inhibitor, trichostatin A, on total histone synthesis, H1(0) synthesis and histone H4 acetylation in peripheral blood lymphocytes increases as a function of increasing age: a model study. |
2002 Jan-Mar |
Exp. Gerontol. |
pmid:11772521
|
Iwata K et al. |
Trichostatin A, a histone deacetylase inhibitor, down-regulates interleukin-12 transcription in SV-40-transformed lung epithelial cells. |
2002 Jul-Aug |
Cell. Immunol. |
pmid:12470611
|
Noss KR et al. |
Methylation state of the prostate specific membrane antigen (PSMA) CpG island in prostate cancer cell lines. |
2002 May-Jun |
Anticancer Res. |
pmid:12168830
|
Rahman I et al. |
Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation. |
2002 May-Jun |
Mol. Cell. Biochem. |
pmid:12162440
|
Henderson C et al. |
Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA). |
2003 |
J. Biol. Chem. |
pmid:12556448
|
Palazzo A et al. |
Cell biology: Tubulin acetylation and cell motility. |
2003 |
Nature |
pmid:12529632
|
Fernandes I et al. |
Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms. |
2003 |
Mol. Cell |
pmid:12535528
|
Rahman MM et al. |
Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages. |
2003 |
Blood |
pmid:12511413
|
Musikacharoen T et al. |
Histone acetylation and activation of cAMP-response element-binding protein regulate transcriptional activation of MKP-M in lipopolysaccharide-stimulated macrophages. |
2003 |
J. Biol. Chem. |
pmid:12511574
|
Gusterson RJ et al. |
The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity. |
2003 |
J. Biol. Chem. |
pmid:12477714
|
Kondo Y et al. |
Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. |
2003 |
Mol. Cell. Biol. |
pmid:12482974
|
Haggarty SJ et al. |
Small molecule modulation of the human chromatid decatenation checkpoint. |
2003 |
Chem. Biol. |
pmid:14700634
|
Kim DK et al. |
Synthesis and biological evaluation of 3-(4-substituted-phenyl)-N-hydroxy-2-propenamides, a new class of histone deacetylase inhibitors. |
2003 |
J. Med. Chem. |
pmid:14667227
|
Huang H et al. |
Expression of P53, P21 in human lung adenocarcinoma A549 cell strains under hypoxia conditions and the effect of TSA on their expression. |
2003 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:15015635
|
Massillon D et al. |
Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. |
2003 |
J. Biol. Chem. |
pmid:12915406
|
Hong CY et al. |
Expression of MIS in the testis is downregulated by tumor necrosis factor alpha through the negative regulation of SF-1 transactivation by NF-kappa B. |
2003 |
Mol. Cell. Biol. |
pmid:12917325
|
Le Masson I et al. |
Yaf9, a novel NuA4 histone acetyltransferase subunit, is required for the cellular response to spindle stress in yeast. |
2003 |
Mol. Cell. Biol. |
pmid:12917332
|
Zhong S et al. |
Phosphorylation at serine 28 and acetylation at lysine 9 of histone H3 induced by trichostatin A. |
2003 |
Oncogene |
pmid:12917630
|
Condon JC et al. |
A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12886011
|
Ryu JR and Arnosti DN |
Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities. |
2003 |
Nucleic Acids Res. |
pmid:12888527
|
Pivot-Pajot C et al. |
Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. |
2003 |
Mol. Cell. Biol. |
pmid:12861021
|
Tominaga K et al. |
MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner. |
2003 |
J. Biol. Chem. |
pmid:14506250
|
Kawai H et al. |
Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor alpha. |
2003 |
Int. J. Cancer |
pmid:14506733
|
Bhakat KK and Mitra S |
CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration. |
2003 |
Carcinogenesis |
pmid:12807730
|
Lopatina NG et al. |
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12810068
|
Liu LT et al. |
Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. |
2003 |
Cancer Res. |
pmid:12810630
|
Shin HJ et al. |
Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation. |
2003 |
Oncogene |
pmid:12813458
|
Kim TY et al. |
Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells. |
2003 |
Oncogene |
pmid:12813468
|
Kim JM et al. |
Changes in histone acetylation during mouse oocyte meiosis. |
2003 |
J. Cell Biol. |
pmid:12835313
|
Camarero N et al. |
Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site. |
2003 |
Nucleic Acids Res. |
pmid:12626711
|
Park KK et al. |
Modulation of Sp1-dependent transcription by a cis-acting E2F element in dhfr promoter. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12788094
|
Shteper PJ et al. |
Role of promoter methylation in regulation of the mammalian heparanase gene. |
2003 |
Oncogene |
pmid:14586400
|
Hirose T et al. |
p53-independent induction of Gadd45 by histone deacetylase inhibitor: coordinate regulation by transcription factors Oct-1 and NF-Y. |
2003 |
Oncogene |
pmid:14586402
|
Kim EJ et al. |
Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML. |
2003 |
Nucleic Acids Res. |
pmid:12954772
|
Brugarolas JB et al. |
TSC2 regulates VEGF through mTOR-dependent and -independent pathways. |
2003 |
Cancer Cell |
pmid:12957289
|
Cimini D et al. |
Histone hyperacetylation in mitosis prevents sister chromatid separation and produces chromosome segregation defects. |
2003 |
Mol. Biol. Cell |
pmid:12972566
|
Schuettengruber B et al. |
Autoregulation of mouse histone deacetylase 1 expression. |
2003 |
Mol. Cell. Biol. |
pmid:12972616
|
Yang Y et al. |
The histone code regulating expression of the imprinted mouse Igf2r gene. |
2003 |
Endocrinology |
pmid:12975326
|
Hu E et al. |
Identification of novel isoform-selective inhibitors within class I histone deacetylases. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12975486
|
Craig JM et al. |
Centromeric chromatin pliability and memory at a human neocentromere. |
2003 |
EMBO J. |
pmid:12743043
|
Enright BP et al. |
Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2'-deoxycytidine. |
2003 |
Biol. Reprod. |
pmid:12748129
|
Jang IC et al. |
Structure and expression of the rice class-I type histone deacetylase genes OsHDAC1-3: OsHDAC1 overexpression in transgenic plants leads to increased growth rate and altered architecture. |
2003 |
Plant J. |
pmid:12581311
|
Bouchain G et al. |
Development of potential antitumor agents. Synthesis and biological evaluation of a new set of sulfonamide derivatives as histone deacetylase inhibitors. |
2003 |
J. Med. Chem. |
pmid:12593661
|
Castro-Galache MD et al. |
Susceptibility of multidrug resistance tumor cells to apoptosis induction by histone deacetylase inhibitors. |
2003 |
Int. J. Cancer |
pmid:12594812
|
Teyssier C et al. |
Receptor-interacting protein 140 binds c-Jun and inhibits estradiol-induced activator protein-1 activity by reversing glucocorticoid receptor-interacting protein 1 effect. |
2003 |
Mol. Endocrinol. |
pmid:12554755
|