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The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. |
2001 |
Mol. Cell. Biol. |
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Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines. |
2001 |
Jpn. J. Cancer Res. |
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2001 |
J. Biol. Chem. |
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Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo. |
2001 |
Carcinogenesis |
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Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. |
2001 |
Cancer Res. |
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The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1). |
2001 |
Mol. Cell. Biol. |
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Histone deacetylase as a new target for cancer chemotherapy. |
2001 |
Cancer Chemother. Pharmacol. |
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Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy. |
2001 Sep-Oct |
Mol. Genet. Metab. |
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Design and synthesis of a novel class of histone deacetylase inhibitors. |
2001 |
Bioorg. Med. Chem. Lett. |
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Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts. |
2001 |
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The role of acetylation in rDNA transcription. |
2001 |
Nucleic Acids Res. |
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Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer. |
2001 |
Exp. Cell Res. |
pmid:11640883
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Involvement of histone deacetylase at two distinct steps in gene regulation during intestinal development in Xenopus laevis. |
2001 |
Dev. Dyn. |
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Laribee RN and Klemsz MJ |
Loss of PU.1 expression following inhibition of histone deacetylases. |
2001 |
J. Immunol. |
pmid:11673528
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Rombouts K et al. |
Trichostatin A, lead compound for development of antifibrogenic drugs. |
2001 Jul-Sep |
Acta Gastroenterol. Belg. |
pmid:11680040
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Chemical agents that promote chromatin compaction radiosensitize tumour cells. |
2001 |
Int. J. Radiat. Biol. |
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Mishra SK et al. |
Dynamic chromatin remodeling on the HER2 promoter in human breast cancer cells. |
2001 |
FEBS Lett. |
pmid:11682064
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Sharma M and Sun Z |
5'TG3' interacting factor interacts with Sin3A and represses AR-mediated transcription. |
2001 |
Mol. Endocrinol. |
pmid:11682623
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Singal R et al. |
Methylation of promoter proximal-transcribed sequences of an embryonic globin gene inhibits transcription in primary erythroid cells and promotes formation of a cell type-specific methyl cytosine binding complex. |
2002 |
J. Biol. Chem. |
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Li J et al. |
Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. |
2001 |
Mol. Cell. Biol. |
pmid:11689710
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Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. |
2001 |
J. Clin. Invest. |
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Amin HM et al. |
Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17). |
2001 |
Br. J. Haematol. |
pmid:11703323
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Sanyal S et al. |
Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. |
2002 |
J. Biol. Chem. |
pmid:11705994
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The histone deacetylase inhibitor trichostatin A influences the development of Drosophila melanogaster. |
2001 |
Cell. Mol. Life Sci. |
pmid:11706997
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Global regulation of post-translational modifications on core histones. |
2002 |
J. Biol. Chem. |
pmid:11709551
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Sachs LM et al. |
An essential role of histone deacetylases in postembryonic organ transformations in Xenopus laevis. |
2001 |
Int. J. Mol. Med. |
pmid:11712071
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Identification of factors mediating the developmental regulation of the early acting -3.9 kb chicken lysozyme enhancer element. |
2001 |
Nucleic Acids Res. |
pmid:11713304
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Hatama S et al. |
Isolation and sequencing of infectious clones of feline foamy virus and a human/feline foamy virus Env chimera. |
2001 |
J. Gen. Virol. |
pmid:11714976
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Yoshioka H et al. |
A novel in vitro system for analyzing parental allele-specific histone acetylation in genomic imprinting. |
2001 |
J. Hum. Genet. |
pmid:11721881
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Stimson KM and Vertino PM |
Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture. |
2002 |
J. Biol. Chem. |
pmid:11733524
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Regulation of the cellular prion protein gene expression depends on chromatin conformation. |
2002 |
J. Biol. Chem. |
pmid:11739375
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Park SH et al. |
Transcriptional regulation of the transforming growth factor beta type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells. |
2002 |
J. Biol. Chem. |
pmid:11744689
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Pujuguet P et al. |
Trichostatin A inhibits beta-casein expression in mammary epithelial cells. |
2001 |
J. Cell. Biochem. |
pmid:11746508
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Matsusue K et al. |
Characterization of mouse metastasis-associated gene 2: genomic structure, nuclear localization signal, and alternative potentials as transcriptional activator and repressor. |
2001 |
DNA Cell Biol. |
pmid:11749719
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Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression. |
2001 |
Am. J. Hematol. |
pmid:11754398
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The effect of the histone deacetylase inhibitor, trichostatin A, on total histone synthesis, H1(0) synthesis and histone H4 acetylation in peripheral blood lymphocytes increases as a function of increasing age: a model study. |
2002 Jan-Mar |
Exp. Gerontol. |
pmid:11772521
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Bordonaro M et al. |
Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate. |
2002 |
Int. J. Cancer |
pmid:11774242
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Kikuchi T et al. |
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. |
2002 |
Int. J. Cancer |
pmid:11774276
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Ginjala V et al. |
Multiple cis elements within the Igf2/H19 insulator domain organize a distance-dependent silencer. A cautionary note. |
2002 |
J. Biol. Chem. |
pmid:11777900
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Williams RJ |
Trichostatin A, an inhibitor of histone deacetylase, inhibits hypoxia-induced angiogenesis. |
2001 |
Expert Opin Investig Drugs |
pmid:11785457
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Gurova KV et al. |
Expression of prostate specific antigen (PSA) is negatively regulated by p53. |
2002 |
Oncogene |
pmid:11791186
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Suenaga M et al. |
Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells. |
2002 |
Int. J. Cancer |
pmid:11807787
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Gong XQ and Li L |
Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation. |
2002 |
J. Biol. Chem. |
pmid:11809751
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Maeda Y et al. |
Repression of hepatocyte nuclear factor 4alpha tumor suppressor p53: involvement of the ligand-binding domain and histone deacetylase activity. |
2002 |
Mol. Endocrinol. |
pmid:11818510
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Gregory RI et al. |
Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells. |
2002 |
J. Biol. Chem. |
pmid:11821379
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Lim Y et al. |
Trichostatin A-induced detransformation correlates with decreased focal adhesion kinase phosphorylation at tyrosine 861 in ras-transformed fibroblasts. |
2002 |
J. Biol. Chem. |
pmid:11821402
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Wilson MA et al. |
The histone deacetylase inhibitor trichostatin A blocks progesterone receptor-mediated transactivation of the mouse mammary tumor virus promoter in vivo. |
2002 |
J. Biol. Chem. |
pmid:11821430
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Deroanne CF et al. |
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling. |
2002 |
Oncogene |
pmid:11821955
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Sourlingas TG et al. |
Histone deacetylase inhibitors induce apoptosis in peripheral blood lymphocytes along with histone H4 acetylation and the expression of the linker histone variant, H1 degrees. |
2001 |
Eur. J. Cell Biol. |
pmid:11824792
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Handumrongkul C et al. |
Distinct sets of cellular genes control the expression of transfected, nuclear-localized genes. |
2002 |
Mol. Ther. |
pmid:11829526
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