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Hyaluronate synthase-2 overexpression alters estrogen dependence and induces histone deacetylase inhibitor-like effects on ER-driven genes in MCF7 breast tumor cells. |
2017 |
Mol. Cell. Endocrinol. |
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Gilardini Montani MS et al. |
Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells. |
2017 |
Cell Oncol (Dordr) |
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HDAC inhibition in the cpfl1 mouse protects degenerating cone photoreceptors in vivo. |
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Hum. Mol. Genet. |
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Suppression of Excessive Histone Deacetylases Activity in Diabetic Hearts Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondria Apoptosis Pathway. |
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J Diabetes Res |
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Li LF et al. |
Trichostatin A attenuates ventilation-augmented epithelial-mesenchymal transition in mice with bleomycin-induced acute lung injury by suppressing the Akt pathway. |
2017 |
PLoS ONE |
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Silencing of ATP4B of ATPase H/K Transporting Beta Subunit by Intragenic Epigenetic Alteration in Human Gastric Cancer Cells. |
2017 |
Oncol. Res. |
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In vitro drug testing based on contractile activity of C2C12 cells in an epigenetic drug model. |
2017 |
Sci Rep |
pmid:28300163
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Chang YW and Singh KP |
Long-term exposure to estrogen enhances chemotherapeutic efficacy potentially through epigenetic mechanism in human breast cancer cells. |
2017 |
PLoS ONE |
pmid:28323900
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Kim YH and Lee JK |
Histone deacetylase inhibitors suppress immature dendritic cell's migration by regulating CC chemokine receptor 1 expression. |
2017 |
Cell. Immunol. |
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In vitro analysis of factors influencing expression as potential determinants of interindividual variation. |
2017 |
Pharmacol Res Perspect |
pmid:28357125
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Shao G et al. |
Inactivation of EGFR/AKT signaling enhances TSA-induced ovarian cancer cell differentiation. |
2017 |
Oncol. Rep. |
pmid:28393191
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Anderson L et al. |
Histone deacetylase inhibition modulates histone acetylation at gene promoter regions and affects genome-wide gene transcription in Schistosoma mansoni. |
2017 |
PLoS Negl Trop Dis |
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Klotho restoration via acetylation of Peroxisome Proliferation-Activated Receptor γ reduces the progression of chronic kidney disease. |
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Kidney Int. |
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High-throughput cell mechanical phenotyping for label-free titration assays of cytoskeletal modifications. |
2017 |
Cytoskeleton (Hoboken) |
pmid:28445605
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HLJ1 (DNAJB4) Gene Is a Novel Biomarker Candidate in Breast Cancer. |
2017 |
OMICS |
pmid:28481734
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Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription. |
2017 |
Cell Res. |
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Biosynthetic Origin of the Hydroxamic Acid Moiety of Trichostatin A: Identification of Unprecedented Enzymatic Machinery Involved in Hydroxylamine Transfer. |
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J. Am. Chem. Soc. |
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Naturally occurring benzoic acid derivatives retard cancer cell growth by inhibiting histone deacetylases (HDAC). |
2017 |
Cancer Biol. Ther. |
pmid:28506198
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Duan HY et al. |
Effect of Histone Deacetylase Inhibition on the Expression of Multidrug Resistance-associated Protein 2 in a Human Placental Trophoblast Cell Line. |
2017 |
Chin. Med. J. |
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Pandey P et al. |
Dynamics of post-translationally modified histones during barley pollen embryogenesis in the presence or absence of the epi-drug trichostatin A. |
2017 |
Plant Reprod |
pmid:28526911
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Ilicic M et al. |
Modulation of Progesterone Receptor Isoform Expression in Pregnant Human Myometrium. |
2017 |
Biomed Res Int |
pmid:28540297
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Yeakley JM et al. |
A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling. |
2017 |
PLoS ONE |
pmid:28542535
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Gurgul A et al. |
The effect of histone deacetylase inhibitor trichostatin A on porcine mesenchymal stem cell transcriptome. |
2017 |
Biochimie |
pmid:28552396
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Hou X et al. |
HDAC inhibitor TSA ameliorates mechanical hypersensitivity and potentiates analgesic effect of morphine in a rat model of bone cancer pain by restoring μ-opioid receptor in spinal cord. |
2017 |
Brain Res. |
pmid:28559159
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Opiela J et al. |
In vitro development and cytological quality of inter-species (porcine→bovine) cloned embryos are affected by trichostatin A-dependent epigenomic modulation of adult mesenchymal stem cells. |
2017 |
Theriogenology |
pmid:28583605
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Bouzelfen A et al. |
Heterogeneous epigenetic regulation of HACE1 in Burkitt- Lymphoma-derived cells. |
2017 |
Leuk. Res. |
pmid:28651105
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Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription. |
2017 |
Nature |
pmid:28682306
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Nucleoporins redistribute inside the nucleus after cell cycle arrest induced by histone deacetylases inhibition. |
2017 |
Nucleus |
pmid:28696859
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Wang SC et al. |
Trichostatin A induces bladder cancer cell death via intrinsic apoptosis at the early phase and Sp1‑survivin downregulation at the late phase of treatment. |
2017 |
Oncol. Rep. |
pmid:28713892
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Jayaraman A et al. |
The epigenetic drug Trichostatin A ameliorates experimental autoimmune encephalomyelitis via T cell tolerance induction and impaired influx of T cells into the spinal cord. |
2017 |
Neurobiol. Dis. |
pmid:28736194
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Green AL et al. |
Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1. |
2017 |
Neuropharmacology |
pmid:28743636
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Stimulation of functional neuronal regeneration from Müller glia in adult mice. |
2017 |
Nature |
pmid:28746305
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Trichostatin A increases embryo and green plant regeneration in wheat. |
2017 |
Plant Cell Rep. |
pmid:28752355
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Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite . |
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Front Cell Infect Microbiol |
pmid:28791254
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Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS. |
2017 |
J Vis Exp |
pmid:28829415
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Tao LL et al. |
TSA increases C/EBP‑α expression by increasing its lysine acetylation in hepatic stellate cells. |
2017 |
Mol Med Rep |
pmid:28849174
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Guo Y et al. |
Trichostatin A attenuates oxidative stress-mediated myocardial injury through the FoxO3a signaling pathway. |
2017 |
Int. J. Mol. Med. |
pmid:28849190
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Kruppel-like factor 4 regulates matrix metalloproteinase and aggrecanase gene expression in chondrocytes. |
2017 |
Cell Tissue Res. |
pmid:28856432
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Histone Deacetylase Inhibitors Relax Mouse Aorta Partly through Their Inhibitory Action on L-Type Ca Channels. |
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J. Pharmacol. Exp. Ther. |
pmid:28860353
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Trichostatin A Sensitizes Hepatocellular Carcinoma Cells to Enhanced NK Cell-mediated Killing by Regulating Immune-related Genes. |
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Cancer Genomics Proteomics |
pmid:28871002
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Buishand FO et al. |
Trichostatin A preferentially reverses the upregulation of gene-expression levels induced by gain of chromosome 7 in colorectal cancer cell lines. |
2018 |
Genes Chromosomes Cancer |
pmid:28940826
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Zhang C et al. |
An epigenetic bioactive composite scaffold with well-aligned nanofibers for functional tendon tissue engineering. |
2018 |
Acta Biomater |
pmid:28963019
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Wei ZQ et al. |
Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation. |
2017 |
World J. Gastroenterol. |
pmid:28974891
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Nagaraja SS et al. |
Effect of Trichostatin A on radiation induced epithelial-mesenchymal transition in A549Â cells. |
2017 |
Biochem. Biophys. Res. Commun. |
pmid:28993195
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Song Y et al. |
Trichostatin A and 5-Aza-2'-Deoxycytidine influence the expression of cold-induced genes in Arabidopsis. |
2017 |
Plant Signal Behav |
pmid:29027833
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Androutsopoulos VP and Spandidos DA |
Antiproliferative effects of TSA, PXD‑101 and MS‑275 in A2780 and MCF7 cells: Acetylated histone H4 and acetylated tubulin as markers for HDACi potency and selectivity. |
2017 |
Oncol. Rep. |
pmid:29039546
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Zhang Z et al. |
Role of histone acetylation in activation of nuclear factor erythroid 2-related factor 2/heme oxygenase 1 pathway by manganese chloride. |
2017 |
Toxicol. Appl. Pharmacol. |
pmid:29054681
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Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in . |
2017 |
Mol. Syst. Biol. |
pmid:29061669
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Histone deacetylase inhibitor stimulates E2 and P4 secretion in sika deer ovarian granulosa cells at a moderate dose. |
2018 |
Cell Biol. Int. |
pmid:29064603
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Ma T et al. |
Suppression of BMP-7 by histone deacetylase 2 promoted apoptosis of renal tubular epithelial cells in acute kidney injury. |
2017 |
Cell Death Dis |
pmid:29072686
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