Rolliniastatin-1

Rolliniastatin-1 is a lipid of Polyketides (PK) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 351 references associated with Rolliniastatin-1 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Rolliniastatin-1

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Rolliniastatin-1

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Total 1

NCBI Entrez Crosslinks

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Authors Title Published Journal PubMed Link
Chih HW et al. Bullatacin, a potent antitumor annonaceous acetogenin, inhibits proliferation of human hepatocarcinoma cell line 2.2.15 by apoptosis induction. 2001 Life Sci. pmid:11521756
Tormo JR et al. Gamma-lactone-Functionalized antitumoral acetogenins are the most potent inhibitors of mitochondrial complex I. 2001 Bioorg. Med. Chem. Lett. pmid:11266168
Jiang S et al. Mimicry of annonaceous acetogenins: enantioselective synthesis of a (4R)-hydroxy analogue having potent antitumor activity. 2002 J. Org. Chem. pmid:12003552
Chiu HF et al. Bullatacin, a potent antitumor Annonaceous acetogenin, induces apoptosis through a reduction of intracellular cAMP and cGMP levels in human hepatoma 2.2.15 cells. 2003 Biochem. Pharmacol. pmid:12527325
Marshall JA et al. A modular synthesis of annonaceous acetogenins. 2003 J. Org. Chem. pmid:12608790
Hamada T et al. Synthesis and inhibitory action of novel acetogenin mimics with bovine heart mitochondrial complex I. 2004 Biochemistry pmid:15035635
Tinsley JM and Roush WR Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. 2005 J. Am. Chem. Soc. pmid:16076173
Keum G et al. Stereoselective syntheses of rolliniastatin 1, rollimembrin, and membranacin. 2005 J. Am. Chem. Soc. pmid:16028952
Tinsley JM et al. Synthesis of (+)-bullatacin via the highly diastereoselective [3+2] annulation reaction of a racemic aldehyde and a nonracemic allylsilane. 2005 Org. Lett. pmid:16146398
Marshall JA and Sabatini JJ An outside-in approach to adjacent bistetrahydrofuran annonaceous acetogenins with C2 core symmetry. Total synthesis of asimicin and a C32 analogue. 2006 Org. Lett. pmid:16869659
Zhao H et al. Advances in Lewis acid controlled carbon-carbon bond-forming reactions enable a concise and convergent total synthesis of bullatacin. 2006 Org. Lett. pmid:16956231
Sinha SC et al. Alteration of the bis-tetrahydrofuran core stereochemistries in asimicin can affect the cytotoxicity. 2008 J. Med. Chem. pmid:18975929
Pomper KW et al. Identification of annonaceous acetogenins in the ripe fruit of the North American pawpaw ( Asimina triloba ). 2009 J. Agric. Food Chem. pmid:19711911
Fato R et al. Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species. 2009 Biochim. Biophys. Acta pmid:19059197
Rodrigues dos Santos Lima LA et al. Two new adjacent bis-tetrahydrofuran annonaceous acetogenins from seeds of Annona cornifolia. 2009 Planta Med. pmid:19039734
Liang YJ et al. Bullatacin triggered ABCB1-overexpressing cell apoptosis via the mitochondrial-dependent pathway. 2009 J. Biomed. Biotechnol. pmid:19639048
Nakamaru-Ogiso E et al. The membrane subunit NuoL(ND5) is involved in the indirect proton pumping mechanism of Escherichia coli complex I. 2010 J. Biol. Chem. pmid:20826797
Kakutani N et al. Exploring the binding site of delta(lac)-acetogenin in bovine heart mitochondrial NADH-ubiquinone oxidoreductase. 2010 Biochemistry pmid:20459120
Luna-Cazares LM and Gonzalez-Esquinca AR Susceptibility of complete bacteria and spheroplasts of Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi to rolliniastatin-2. 2010 Nat. Prod. Res. pmid:20582808
Nakamaru-Ogiso E et al. The ND2 subunit is labeled by a photoaffinity analogue of asimicin, a potent complex I inhibitor. 2010 FEBS Lett. pmid:20074573