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Epothilone D prevents binge methamphetamine-mediated loss of striatal dopaminergic markers. |
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J. Neurochem. |
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Nanomolar concentrations of epothilone D inhibit the proliferation of glioma cells and severely affect their tubulin cytoskeleton. |
2003 |
J. Neurooncol. |
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Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. |
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J. Neurosci. |
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Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027. |
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J. Neurosci. |
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The microtubule-stabilizing agent, epothilone D, reduces axonal dysfunction, neurotoxicity, cognitive deficits, and Alzheimer-like pathology in an interventional study with aged tau transgenic mice. |
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J. Neurosci. |
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Probing the SAR of dEpoB via chemical synthesis: a total synthesis evaluation of C26-(1,3-dioxolanyl)-12,13-desoxyepothilone B. |
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J. Org. Chem. |
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Total syntheses of [17]- and [18]dehydrodesoxyepothilones B via a concise ring-closing metathesis-based strategy: correlation of ring size with biological activity in the epothilone series. |
2002 |
J. Org. Chem. |
pmid:12398497
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Total synthesis of epothilones B and D: stannane equivalents for beta-keto ester dianions. |
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J. Org. Chem. |
pmid:18991385
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Total syntheses of epothilones B and d. |
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J. Org. Chem. |
pmid:15609966
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Total synthesis of epothilone D: the nerol/macroaldolization approach. |
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J. Org. Chem. |
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