6-deoxyerythronolide B

6-deoxyerythronolide B is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Biosynthetic Pathways and Synthesis. The associated genes with 6-deoxyerythronolide B are LARGE gene. The related lipids are Propionate.

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Introduction

To understand associated biological information of 6-deoxyerythronolide B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 6-deoxyerythronolide B

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 6-deoxyerythronolide B through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

What functions are associated with 6-deoxyerythronolide B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 6-deoxyerythronolide B?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 6-deoxyerythronolide B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 6-deoxyerythronolide B

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Authors Title Published Journal PubMed Link
Chen D et al. Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. 2014 PLoS ONE pmid:25250723
Paterson I and Temal-Laïb T Toward the combinatorial synthesis of polyketide libraries: asymmetric aldol reactions with alpha-chiral aldehydes on solid support. 2002 Org. Lett. pmid:12123354
Crimmins MT and Slade DJ Formal synthesis of 6-deoxyerythronolide B. 2006 Org. Lett. pmid:16671814
Pinto A et al. 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. 2012 Org. Lett. pmid:22519860
Pieper R et al. Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases. 1995 Nature pmid:7477343
Cupp-Vickery JR and Poulos TL Structure of cytochrome P450eryF involved in erythromycin biosynthesis. 1995 Nat. Struct. Biol. pmid:7749919
Akey DL et al. Structural basis for macrolactonization by the pikromycin thioesterase. 2006 Nat. Chem. Biol. pmid:16969372
Dechert-Schmitt AM et al. Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. 2014 Nat Prod Rep pmid:24514754
Stang EM and White MC Total synthesis and study of 6-deoxyerythronolide B by late-stage C-H oxidation. 2009 Nat Chem pmid:21378935
Gaisser S et al. Parallel pathways for oxidation of 14-membered polyketide macrolactones in Saccharopolyspora erythraea. 2002 Mol. Microbiol. pmid:11994157