6-deoxyerythronolide B

6-deoxyerythronolide B is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Biosynthetic Pathways and Synthesis. The associated genes with 6-deoxyerythronolide B are LARGE gene. The related lipids are Propionate.

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Introduction

To understand associated biological information of 6-deoxyerythronolide B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 6-deoxyerythronolide B

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 6-deoxyerythronolide B through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

What functions are associated with 6-deoxyerythronolide B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 6-deoxyerythronolide B?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 6-deoxyerythronolide B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 6-deoxyerythronolide B

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Authors Title Published Journal PubMed Link
Hu Z et al. A specific role of the Saccharopolyspora erythraea thioesterase II gene in the function of modular polyketide synthases. 2003 Microbiology (Reading, Engl.) pmid:12904561
Zhang H et al. Probing the heterologous metabolism supporting 6-deoxyerythronolide B biosynthesis in Escherichia coli. 2009 Microb Biotechnol pmid:21261933
Wang Y and Pfeifer BA 6-deoxyerythronolide B production through chromosomal localization of the deoxyerythronolide B synthase genes in E. coli. 2008 Metab. Eng. pmid:17959404
Wu J et al. Construction and performance of heterologous polyketide-producing K-12- and B-derived Escherichia coli. 2010 Lett. Appl. Microbiol. pmid:20565574
Khosla C Structures and mechanisms of polyketide synthases. 2009 J. Org. Chem. pmid:19711990
Keatinge-Clay A Crystal structure of the erythromycin polyketide synthase dehydratase. 2008 J. Mol. Biol. pmid:18952099
Murli S et al. Metabolic engineering of Escherichia coli for improved 6-deoxyerythronolide B production. 2003 J. Ind. Microbiol. Biotechnol. pmid:12898389
Boghigian BA et al. Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. 2011 J. Ind. Microbiol. Biotechnol. pmid:21487833
Ward SL et al. Precursor-directed biosynthesis of 6-deoxyerythronolide B analogues is improved by removal of the initial catalytic sites of the polyketide synthase. 2007 J. Ind. Microbiol. Biotechnol. pmid:17033784
Lau J et al. Development of a high cell-density fed-batch bioprocess for the heterologous production of 6-deoxyerythronolide B in Escherichia coli. 2004 J. Biotechnol. pmid:15099909