| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ashley GW and Carney JR | API-mass spectrometry of polyketides. II. Fragmentation analysis of 6-deoxyerythronolide B analogs. | 2004 | J. Antibiot. | pmid:15580959 |
| Kennedy J and Kealey JT | Tools for metabolic engineering in Escherichia coli: inactivation of panD by a point mutation. | 2004 | Anal. Biochem. | pmid:15033515 |
| Desai RP et al. | Combining classical, genetic, and process strategies for improved precursor-directed production of 6-deoxyerythronolide B analogues. | 2004 Jan-Feb | Biotechnol. Prog. | pmid:14763821 |
| Murli S et al. | Chemobiosynthesis of novel 6-deoxyerythronolide B analogues by mutation of the loading module of 6-deoxyerythronolide B synthase 1. | 2005 | Appl. Environ. Microbiol. | pmid:16085842 |
| Akey DL et al. | Structural basis for macrolactonization by the pikromycin thioesterase. | 2006 | Nat. Chem. Biol. | pmid:16969372 |
| González-Lergier J et al. | Analysis of the maximum theoretical yield for the synthesis of erythromycin precursors in Escherichia coli. | 2006 | Biotechnol. Bioeng. | pmid:16619212 |
| Crimmins MT and Slade DJ | Formal synthesis of 6-deoxyerythronolide B. | 2006 | Org. Lett. | pmid:16671814 |
| Khosla C et al. | Structure and mechanism of the 6-deoxyerythronolide B synthase. | 2007 | Annu. Rev. Biochem. | pmid:17328673 |
| Sharma KK and Boddy CN | The thioesterase domain from the pimaricin and erythromycin biosynthetic pathways can catalyze hydrolysis of simple thioester substrates. | 2007 | Bioorg. Med. Chem. Lett. | pmid:17428661 |
| Wang Y et al. | Improving heterologous polyketide production in Escherichia coli by overexpression of an S-adenosylmethionine synthetase gene. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17876579 |
| Ward SL et al. | Precursor-directed biosynthesis of 6-deoxyerythronolide B analogues is improved by removal of the initial catalytic sites of the polyketide synthase. | 2007 | J. Ind. Microbiol. Biotechnol. | pmid:17033784 |
| Keatinge-Clay A | Crystal structure of the erythromycin polyketide synthase dehydratase. | 2008 | J. Mol. Biol. | pmid:18952099 |
| Wang Y and Pfeifer BA | 6-deoxyerythronolide B production through chromosomal localization of the deoxyerythronolide B synthase genes in E. coli. | 2008 | Metab. Eng. | pmid:17959404 |
| Stang EM and White MC | Total synthesis and study of 6-deoxyerythronolide B by late-stage C-H oxidation. | 2009 | Nat Chem | pmid:21378935 |
| Zhang H et al. | Probing the heterologous metabolism supporting 6-deoxyerythronolide B biosynthesis in Escherichia coli. | 2009 | Microb Biotechnol | pmid:21261933 |
| Khosla C | Structures and mechanisms of polyketide synthases. | 2009 | J. Org. Chem. | pmid:19711990 |
| Pistorino M and Pfeifer BA | Efficient experimental design and micro-scale medium enhancement of 6-deoxyerythronolide B production through Escherichia coli. | 2009 Sep-Oct | Biotechnol. Prog. | pmid:19634176 |
| Kapur S et al. | Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21127271 |
| Zhang H et al. | Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production in Escherichia coli. | 2010 | Biotechnol. Bioeng. | pmid:19806677 |
| Wu J et al. | Construction and performance of heterologous polyketide-producing K-12- and B-derived Escherichia coli. | 2010 | Lett. Appl. Microbiol. | pmid:20565574 |
6-deoxyerythronolide B
6-deoxyerythronolide B is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Biosynthetic Pathways and Synthesis. The associated genes with 6-deoxyerythronolide B are LARGE gene. The related lipids are Propionate.
Cross Reference
Introduction
To understand associated biological information of 6-deoxyerythronolide B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 6-deoxyerythronolide B?
There are no associated biomedical information in the current reference collection.
No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 6-deoxyerythronolide B
Lipid pathways are not clear in current pathway databases. We organized associated pathways with 6-deoxyerythronolide B through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 6-deoxyerythronolide B?
There are no associated biomedical information in the current reference collection.
What functions are associated with 6-deoxyerythronolide B?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 6-deoxyerythronolide B?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 6-deoxyerythronolide B?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 6-deoxyerythronolide B?
There are no associated biomedical information in the current reference collection.