| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Roddis M et al. | Structural elucidation studies on 14- and 16-membered macrolide aglycones by accurate-mass electrospray sequential mass spectrometry. | 2002 | J. Am. Soc. Mass Spectrom. | pmid:12148810 |
| Gaisser S et al. | Parallel pathways for oxidation of 14-membered polyketide macrolactones in Saccharopolyspora erythraea. | 2002 | Mol. Microbiol. | pmid:11994157 |
| Winn PJ et al. | Comparison of the dynamics of substrate access channels in three cytochrome P450s reveals different opening mechanisms and a novel functional role for a buried arginine. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11959989 |
| Pfeifer B et al. | Process and metabolic strategies for improved production of Escherichia coli-derived 6-deoxyerythronolide B. | 2002 | Appl. Environ. Microbiol. | pmid:12089005 |
| Tsai SC et al. | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases. | 2002 | Biochemistry | pmid:12379102 |
| Lombó F et al. | Enhancing the atom economy of polyketide biosynthetic processes through metabolic engineering. | 2001 Jul-Aug | Biotechnol. Prog. | pmid:11485419 |
| Ferber D | Microbiology. Possible new route to polyketide synthesis. | 2001 | Science | pmid:11253181 |
| Tsuji SY et al. | Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules. | 2001 | Biochemistry | pmid:11327852 |
| Pfeifer BA et al. | Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli. | 2001 | Science | pmid:11230695 |
| Kim C et al. | The role of serine-246 in cytochrome P450eryF-catalyzed hydroxylation of 6-deoxyerythronolide B. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11388449 |
| Yin Y et al. | Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11412964 |
| Leaf T et al. | Precursor-directed biosynthesis of 6-deoxyerythronolide B analogs in Streptomyces coelicolor: understanding precursor effects. | 2000 Jul-Aug | Biotechnol. Prog. | pmid:10933827 |
| Wilkinson B et al. | Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase. | 2000 | Chem. Biol. | pmid:10662692 |
| Xiang H et al. | An A245T mutation conveys on cytochrome P450eryF the ability to oxidize alternative substrates. | 2000 | J. Biol. Chem. | pmid:10956654 |
| Ziermann R and Betlach MC | Recombinant polyketide synthesis in Streptomyces: engineering of improved host strains. | 1999 | BioTechniques | pmid:9894599 |
| Xue Q et al. | A multiplasmid approach to preparing large libraries of polyketides. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10518520 |
| Lau J et al. | Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units. | 1999 | Biochemistry | pmid:9931032 |
| Jacobsen JR et al. | Spontaneous priming of a downstream module in 6-deoxyerythronolide B synthase leads to polyketide biosynthesis. | 1998 | Biochemistry | pmid:9538011 |
| Rowe CJ et al. | Construction of new vectors for high-level expression in actinomycetes. | 1998 | Gene | pmid:9714812 |
| Jacobsen JR et al. | Precursor-directed biosynthesis of 12-ethyl erythromycin. | 1998 | Bioorg. Med. Chem. | pmid:9784859 |
6-deoxyerythronolide B
6-deoxyerythronolide B is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Biosynthetic Pathways and Synthesis. The associated genes with 6-deoxyerythronolide B are LARGE gene. The related lipids are Propionate.
Cross Reference
Introduction
To understand associated biological information of 6-deoxyerythronolide B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 6-deoxyerythronolide B?
There are no associated biomedical information in the current reference collection.
No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 6-deoxyerythronolide B
Lipid pathways are not clear in current pathway databases. We organized associated pathways with 6-deoxyerythronolide B through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 6-deoxyerythronolide B?
There are no associated biomedical information in the current reference collection.
What functions are associated with 6-deoxyerythronolide B?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 6-deoxyerythronolide B?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 6-deoxyerythronolide B?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 6-deoxyerythronolide B?
There are no associated biomedical information in the current reference collection.