6-deoxyerythronolide B

6-deoxyerythronolide B is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Biosynthetic Pathways and Synthesis. The associated genes with 6-deoxyerythronolide B are LARGE gene. The related lipids are Propionate.

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Introduction

To understand associated biological information of 6-deoxyerythronolide B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 6-deoxyerythronolide B

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 6-deoxyerythronolide B through full-text articles, including metabolic pathways or pathways of biological mechanisms.

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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

What functions are associated with 6-deoxyerythronolide B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 6-deoxyerythronolide B?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 6-deoxyerythronolide B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 6-deoxyerythronolide B

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Authors Title Published Journal PubMed Link
Desai RP et al. Combining classical, genetic, and process strategies for improved precursor-directed production of 6-deoxyerythronolide B analogues. 2004 Jan-Feb Biotechnol. Prog. pmid:14763821
Pistorino M and Pfeifer BA Efficient experimental design and micro-scale medium enhancement of 6-deoxyerythronolide B production through Escherichia coli. 2009 Sep-Oct Biotechnol. Prog. pmid:19634176
Lombó F et al. Enhancing the atom economy of polyketide biosynthetic processes through metabolic engineering. 2001 Jul-Aug Biotechnol. Prog. pmid:11485419
Chuck JA et al. Molecular recognition of diketide substrates by a beta-ketoacyl-acyl carrier protein synthase domain within a bimodular polyketide synthase. 1997 Chem. Biol. pmid:9375254
Wilkinson B et al. Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase. 2000 Chem. Biol. pmid:10662692
Donadio S and Katz L Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea. 1992 Gene pmid:1547954
Rowe CJ et al. Construction of new vectors for high-level expression in actinomycetes. 1998 Gene pmid:9714812
Gao X et al. Total synthesis of 6-deoxyerythronolide B via C-C bond-forming transfer hydrogenation. 2013 J. Am. Chem. Soc. pmid:23464668
Roddis M et al. Structural elucidation studies on 14- and 16-membered macrolide aglycones by accurate-mass electrospray sequential mass spectrometry. 2002 J. Am. Soc. Mass Spectrom. pmid:12148810
Ashley GW and Carney JR API-mass spectrometry of polyketides. II. Fragmentation analysis of 6-deoxyerythronolide B analogs. 2004 J. Antibiot. pmid:15580959