6-deoxyerythronolide B

6-deoxyerythronolide B is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Biosynthetic Pathways and Synthesis. The associated genes with 6-deoxyerythronolide B are LARGE gene. The related lipids are Propionate.

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Introduction

To understand associated biological information of 6-deoxyerythronolide B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 6-deoxyerythronolide B

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 6-deoxyerythronolide B through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

What functions are associated with 6-deoxyerythronolide B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 6-deoxyerythronolide B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 6-deoxyerythronolide B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 6-deoxyerythronolide B?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 6-deoxyerythronolide B

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Authors Title Published Journal PubMed Link
Boghigian BA et al. Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. 2011 J. Ind. Microbiol. Biotechnol. pmid:21487833
Boghigian BA et al. Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. 2011 Biotechnol. Bioeng. pmid:21337322
Pinto A et al. 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. 2012 Org. Lett. pmid:22519860
Yuzawa S et al. Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases. 2012 Biochemistry pmid:22509729
He Z et al. [Reconstruction of erythromycin macrocyclic lactone synthesis pathway in Escherichia coli]. 2012 Sheng Wu Gong Cheng Xue Bao pmid:22667124
Gao X et al. Total synthesis of 6-deoxyerythronolide B via C-C bond-forming transfer hydrogenation. 2013 J. Am. Chem. Soc. pmid:23464668
Chen D et al. Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. 2014 PLoS ONE pmid:25250723
Dechert-Schmitt AM et al. Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. 2014 Nat Prod Rep pmid:24514754
Fayed B et al. Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. 2015 Appl. Environ. Microbiol. pmid:26431970
Yang J et al. Improving heterologous polyketide production in Escherichia coli by transporter engineering. 2015 Appl. Microbiol. Biotechnol. pmid:26062534