Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Harikrishnan P and Harden PN | Tacrolimus can resolve cyclosporin-induced gingival hyperplasia. | 1999 | Nephrol. Dial. Transplant. | pmid:10435907 |
Tsuji Y et al. | Effects of cyclosporin A, FK506 and steroid hormones on hair growth. | 1999 | Exp. Dermatol. | pmid:10439282 |
Sheikh AM et al. | Concomitant human immunodeficiency virus protease inhibitor therapy markedly reduces tacrolimus metabolism and increases blood levels. | 1999 | Transplantation | pmid:10440408 |
Moxey-Mims MM | Increased incidence of insulin-dependent diabetes mellitus in pediatric renal transplant patients receiving tacrolimus (FK506) | 1999 | Transplantation | pmid:10440413 |
Magee CC et al. | Nocardial infection in a renal transplant recipient on tacrolimus and mycophenolate mofetil. | 1999 | Clin. Nephrol. | pmid:10442495 |
Kur F et al. | Tacrolimus (FK506) as primary immunosuppressant after lung transplantation. | 1999 | Thorac Cardiovasc Surg | pmid:10443520 |
Uchiyama H et al. | Approach to withdrawal from tacrolimus in a fully allogeneic murine skin graft model. | 1999 | Immunology | pmid:10447745 |
Volbracht C et al. | ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation. | 1999 | Mol. Med. | pmid:10449809 |
Goulet MT et al. | C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10450986 |
Armstrong HM et al. | Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10450987 |