tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Neuroaspergillosis D020953 2 associated lipids
Delayed Graft Function D051799 2 associated lipids
Uterine Cervical Dysplasia D002578 2 associated lipids
Venous Insufficiency D014689 2 associated lipids
Cytomegalovirus Retinitis D017726 2 associated lipids
Telangiectasis D013684 2 associated lipids
Still's Disease, Adult-Onset D016706 2 associated lipids
Incontinentia Pigmenti D007184 2 associated lipids
Vitiligo D014820 2 associated lipids
Hypopigmentation D017496 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Waer M New immunosuppressive agents for organ transplantation. 1997 Acta Clin Belg pmid:9351290
Liang J et al. Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. 1999 Acta Crystallogr. D Biol. Crystallogr. pmid:10089303
Bracher A et al. Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. 2011 Acta Crystallogr. D Biol. Crystallogr. pmid:21636895
Li P et al. Structure of the N-terminal domain of human FKBP52. 2003 Acta Crystallogr. D Biol. Crystallogr. pmid:12499534
Schreier MH Immunophilins and immunosuppression by cyclosporins and macrolide structures. 1994 Acta Derm Venereol Suppl (Stockh) pmid:7521103
Segura S et al. Eczema herpeticum during treatment of atopic dermatitis with 1% pimecrolimus cream. 2005 Acta Derm. Venereol. pmid:16396803
Mercader P et al. Treatment of protein contact dermatitis with topical tacrolimus. 2005 Acta Derm. Venereol. pmid:16396818
Jungersted JM et al. Effects of topical corticosteroid and tacrolimus on ceramides and irritancy to sodium lauryl sulphate in healthy skin. 2011 Acta Derm. Venereol. pmid:21365172
Zattra E et al. Labial melanotic macule after application of topical tacrolimus: two case reports. 2010 Acta Derm. Venereol. pmid:20814635
Pagliarello C and Paradisi A Topical tacrolimus is useful for avoiding suction-blister epidermal grafting depigmentation in non-segmental vitiligo: a case report. 2012 Acta Derm. Venereol. pmid:22101735
Reitamo S et al. Long-term treatment with 0.1% tacrolimus ointment in adults with atopic dermatitis: results of a two-year, multicentre, non-comparative study. 2007 Acta Derm. Venereol. pmid:17721647
Mandelin J et al. Leg ulcers treated with topical tacrolimus in patients with rheumatoid arthritis. 2010 Acta Derm. Venereol. pmid:21057750
Mandelin J et al. One-year treatment with 0.1% tacrolimus ointment versus a corticosteroid regimen in adults with moderate to severe atopic dermatitis: A randomized, double-blind, comparative trial. 2010 Acta Derm. Venereol. pmid:20169301
Ujiie H et al. Successful treatment of nail lichen planus with topical tacrolimus. 2010 Acta Derm. Venereol. pmid:20169322
Halvorsen JA and Aasebø W Oral tacrolimus treatment of pruritus in prurigo nodularis. 2015 Acta Derm. Venereol. pmid:25804254
Honda Y et al. Disseminated Mycobacterium mantenii infection with multiple purulent cutaneous lesions. 2015 Acta Derm. Venereol. pmid:25881714
De Rie MA et al. Soluble interleukin-2 receptor (sIL-2R) is a marker of disease activity in psoriasis: a comparison of sIL-2R, sCD27, sCD4, sCD8 and sICAM-1. 1996 Acta Derm. Venereol. pmid:8891007
Yamamoto T and Nishioka K Deep dermatophytosis during topical tacrolimus therapy for psoriasis. 2003 Acta Derm. Venereol. pmid:12926803
Sand C Topical tacrolimus ointment may induce skin tags in treated patients. 2003 Acta Derm. Venereol. pmid:12926817
Park SW et al. Topical tacrolimus (FK506): treatment failure in four cases of alopecia universalis. 2002 Acta Derm. Venereol. pmid:12430746