tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hydronephrosis D006869 4 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Hyperparathyroidism, Secondary D006962 4 associated lipids
Bone Diseases D001847 4 associated lipids
Hepatitis B, Chronic D019694 4 associated lipids
Neoplasms, Second Primary D016609 4 associated lipids
Eczema D004485 4 associated lipids
Foot Ulcer D016523 4 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Neuritis D009443 4 associated lipids
Simian Acquired Immunodeficiency Syndrome D016097 4 associated lipids
Intracranial Hypertension D019586 4 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Autonomic Nervous System Diseases D001342 4 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Optic Nerve Injuries D020221 4 associated lipids
Headache D006261 4 associated lipids
Pain, Intractable D010148 4 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Reflex Sympathetic Dystrophy D012019 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Chen YH et al. [Nephrotoxicity of tacrolimus and preventive effect of diltiazem: experiment with rats]. 2009 Zhonghua Yi Xue Za Zhi pmid:19595068
Lu AW et al. [Dual, triple, and quadruple oral tacrolimus-based immunosuppression regimens after orthotopic liver transplantation: a randomised comparative study of regimens]. 2006 Zhonghua Yi Xue Za Zhi pmid:17313848
Li YX et al. [Preliminary experience with partial tolerance protocol in small bowel transplantation]. 2009 Zhonghua Yi Xue Za Zhi pmid:20137270
Feng HY et al. [Therapeutic efficacy and safety of tacrolimus for intractable myasthenia gravis: a report of 36 patients]. 2011 Zhonghua Yi Xue Za Zhi pmid:22333101
Huang HF et al. [Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: a 4-year prospective study]. 2011 Zhonghua Yi Xue Za Zhi pmid:22333250
Zhao SM et al. [Promotion of in vitro long term expansion of primitive multipotential hematopoietic cells by transduced JAK2 gene]. 2004 Zhonghua Yi Xue Za Zhi pmid:15329285
Wang J and Fan H [Assessment of P70S6 kinase phosphorylation after liver transplantation by phospho-flow cytometry]. 2014 Zhonghua Yi Xue Za Zhi pmid:25623311
Xia WL et al. [Effects of ciclosporin and tacrolimus on replication of hepatitis B virus in vitro: a comparative study]. 2006 Zhonghua Yi Xue Za Zhi pmid:16620716
Lü DC et al. [Effect of FK506 on axonal regeneration of rat sciatic nerve in regeneration chamber: an experimental study]. 2005 Zhonghua Yi Xue Za Zhi pmid:16313776
Zhang WG et al. [Favorable effect of chitosan sustained-release FK506 incorporated conduits on axonal regeneration in rat sciatic nerve]. 2006 Zhonghua Yi Xue Za Zhi pmid:16784713