Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kagaya H et al. | Prediction of Tacrolimus Exposure by CYP3A5 Genotype and Exposure of Co-Administered Everolimus in Japanese Renal Transplant Recipients. | 2018 | Int J Mol Sci | pmid:29547545 |
Tsujimura K et al. | Effect of Influenza Vaccine in Patients With Kidney Transplant. | 2018 | Transplant. Proc. | pmid:30316375 |
Hu YN et al. | High-dose calcineurin inhibitor-free everolimus as a maintenance regimen for heart transplantation may be a risk factor for Pneumocystis pneumonia. | 2017 | Transpl Infect Dis | pmid:28425200 |
Epperla N et al. | Impact of treatment and outcomes for patients with posttransplant drug-associated thrombotic microangiopathy. | 2017 | Transfusion | pmid:28836275 |
Müller EG et al. | Tacrolimus eye drops as monotherapy for vernal keratoconjunctivitis: a randomized controlled trial. | 2017 | Arq Bras Oftalmol | pmid:28832739 |
Solmaz S et al. | Tacrolimus-Induced Diabetic Ketoacidosis After Allogeneic Bone Marrow Transplant. | 2017 | Exp Clin Transplant | pmid:26643544 |
Arns W et al. | Pharmacokinetics and Clinical Outcomes of Generic Tacrolimus (Hexal) Versus Branded Tacrolimus in De Novo Kidney Transplant Patients: A Multicenter, Randomized Trial. | 2017 | Transplantation | pmid:28658202 |
Agarwal SK et al. | Impact of type of calcineurin inhibitor on post-transplant tuberculosis: Single-center study from India. | 2017 | Transpl Infect Dis | pmid:27775825 |
Charman C | A 5-year randomized trial on the safety and efficacy of pimecrolimus in atopic dermatitis: a critical appraisal - comment. | 2017 | Br. J. Dermatol. | pmid:28858382 |
Zaza G et al. | Impact of maintenance immunosuppressive therapy on the fecal microbiome of renal transplant recipients: Comparison between an everolimus- and a standard tacrolimus-based regimen. | 2017 | PLoS ONE | pmid:28542523 |
Ito A et al. | Sex Differences in the Blood Concentration of Tacrolimus in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients with CYP3A5*3/*3. | 2017 | Biochem. Genet. | pmid:28324194 |
Xiang DM et al. | [The observation of tacrolimus eye drops preventing the early immunological rejection after penetrating keratoplasty for fungal keratitis]. | 2017 | Zhonghua Yan Ke Za Zhi | pmid:28412805 |
Ayar Y et al. | Risk Factors Affecting Graft and Patient Survivals After Transplantation From Deceased Donors in a Developing Country: A Single-Center Experience. | 2017 | Transplant. Proc. | pmid:28219583 |
Keller F et al. | Correlation between pharmacokinetics of tacrolimus and pharmacodynamics on NFAT-regulated gene expression in stable kidney transplant recipients
. | 2017 | Clin. Nephrol. | pmid:28025957 |
Ren L et al. | Donors FMO3 polymorphisms affect tacrolimus elimination in Chinese liver transplant patients. | 2017 | Pharmacogenomics | pmid:28084894 |
Li R et al. | Effect of narrow band ultraviolet B phototherapy as monotherapy or combination therapy for vitiligo: a meta-analysis. | 2017 | Photodermatol Photoimmunol Photomed | pmid:27696531 |
Billing H et al. | Single-Nucleotide Polymorphism of CYP3A5 Impacts the Exposure to Tacrolimus in Pediatric Renal Transplant Recipients: A Pharmacogenetic Substudy of the TWIST Trial. | 2017 | Ther Drug Monit | pmid:28030534 |
Ordóñez-Robles M et al. | Streptomyces tsukubaensis as a new model for carbon repression: transcriptomic response to tacrolimus repressing carbon sources. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28983826 |
Dabrowska-Zamojcin E et al. | KCNJ11 and KCNQ1 Gene Polymorphisms Are Not Associated with Post-Transplant Diabetes Mellitus in Kidney Allograft Recipients Treated with Tacrolimus. | 2017 | Folia Biol. (Praha) | pmid:28805561 |
Furukawa T et al. | A case of neuromyelitis optica spectrum disorder (NMOSD) with Sjögren's syndrome manifested only brain involvement by preceding parotitis. | 2017 | Rinsho Shinkeigaku | pmid:28132975 |