Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nishimoto M et al. | Drug interactions and safety profiles with concomitant use of caspofungin and calcineurin inhibitors in allogeneic haematopoietic cell transplantation. | 2017 | Br J Clin Pharmacol | pmid:28407449 |
Bao LQ et al. | Tacrolimus prevents murine cerebral malaria. | 2017 | Immunology | pmid:27546479 |
Taber DJ et al. | Tacrolimus Trough Concentration Variability and Disparities in African American Kidney Transplantation. | 2017 | Transplantation | pmid:28658199 |
Cong M et al. | Novel oleyl amine-modified polymannuronic acid micelle loading tacrolimus for therapy of allergic conjunctivitis. | 2017 | Int. J. Biol. Macromol. | pmid:28655660 |
Yu Y et al. | Tacrolimus downregulates inflammation by regulating pro‑/anti‑inflammatory responses in LPS‑induced keratitis. | 2017 | Mol Med Rep | pmid:28849181 |
Schulte K et al. | Late conversion from tacrolimus to a belatacept-based immuno-suppression regime in kidney transplant recipients improves renal function, acid-base derangement and mineral-bone metabolism. | 2017 | J. Nephrol. | pmid:28540602 |
Miyamoto T et al. | Comparison of cyclosporine and tacrolimus combined with mycophenolate mofetil in prophylaxis for graft-versus-host disease after reduced-intensity umbilical cord blood transplantation. | 2017 | Int. J. Hematol. | pmid:27686673 |
Liu G et al. | FK506 Attenuates the Inflammation in Rat Spinal Cord Injury by Inhibiting the Activation of NF-κB in Microglia Cells. | 2017 | Cell. Mol. Neurobiol. | pmid:27572744 |
Shah SZA et al. | Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters. | 2017 | Neurotherapeutics | pmid:28083805 |
Koguchi-Yoshioka H et al. | Intravenous immunoglobulin contributes to the control of antimelanoma differentiation-associated protein 5 antibody-associated dermatomyositis with palmar violaceous macules/papules. | 2017 | Br. J. Dermatol. | pmid:28346662 |
Nambu M et al. | A calcineurin antifungal strategy with analogs of FK506. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28412204 |
Hayashi Y et al. | Neuropathological findings from an autopsied case showing posterior reversible encephalopathy syndrome-like neuroradiological findings associated with premedication including tacrolimus for autologous peripheral blood stem cell transplantation. | 2017 | J. Neurol. Sci. | pmid:28320172 |
Sinha A et al. | Mycophenolate mofetil is inferior to tacrolimus in sustaining remission in children with idiopathic steroid-resistant nephrotic syndrome. | 2017 | Kidney Int. | pmid:28318625 |
Sikma MA et al. | High tacrolimus blood concentrations early after lung transplantation and the risk of kidney injury. | 2017 | Eur. J. Clin. Pharmacol. | pmid:28132082 |
Sukma Dewi I et al. | Association of Serum MiR-142-3p and MiR-101-3p Levels with Acute Cellular Rejection after Heart Transplantation. | 2017 | PLoS ONE | pmid:28125729 |
Rozen-Zvi B et al. | Association of the combination of time-weighted variability of tacrolimus blood level and exposure to low drug levels with graft survival after kidney transplantation. | 2017 | Nephrol. Dial. Transplant. | pmid:28025383 |
Qi JC et al. | Tacrolimus protects vascular endothelial cells from injuries caused by Ox-LDL by regulating endoplasmic reticulum stress. | 2017 | Eur Rev Med Pharmacol Sci | pmid:28975964 |
Hirano Y et al. | Prolonged Administration of Twice-Daily Bolus Intravenous Tacrolimus in the Early Phase After Lung Transplantation. | 2017 | Ann. Transplant. | pmid:28798289 |
Higashi H et al. | First successful perinatal management of pregnancy after ABO-incompatible liver transplantation. | 2017 | World J. Gastroenterol. | pmid:28210092 |
Larche M and McGonagle D | A case of resistant spondyloarthritis (SpA) that responded to tacrolimus and mycophenolate treatment initiated at the time of renal transplantation for unrelated renal failure. | 2017 | Scand. J. Rheumatol. | pmid:26971928 |