tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bao LQ et al. | Tacrolimus prevents murine cerebral malaria. | 2017 | Immunology | pmid:27546479 |
| Solmaz S et al. | Tacrolimus-Induced Diabetic Ketoacidosis After Allogeneic Bone Marrow Transplant. | 2017 | Exp Clin Transplant | pmid:26643544 |
| Baluch A et al. | Successful management of Mycobacterium haemophilum lower extremity cutaneous infection in a matched-unrelated donor stem cell transplant recipient. | 2017 | Transpl Infect Dis | pmid:27775824 |
| Taber DJ et al. | Tacrolimus Trough Concentration Variability and Disparities in African American Kidney Transplantation. | 2017 | Transplantation | pmid:28658199 |
| Li X et al. | Tacrolimus Monotherapy after Intravenous Methylprednisolone in Adults with Minimal Change Nephrotic Syndrome. | 2017 | J. Am. Soc. Nephrol. | pmid:27807213 |
| Yu Y et al. | Tacrolimus downregulates inflammation by regulating pro‑/anti‑inflammatory responses in LPS‑induced keratitis. | 2017 | Mol Med Rep | pmid:28849181 |
| Jin J et al. | Effects of metformin on hyperglycemia in an experimental model of tacrolimus- and sirolimus-induced diabetic rats. | 2017 | Korean J. Intern. Med. | pmid:27688296 |
| Neustadtl AL et al. | Reduced cortical excitatory synapse number in APOE4 mice is associated with increased calcineurin activity. | 2017 | Neuroreport | pmid:28542068 |
| Schulte K et al. | Late conversion from tacrolimus to a belatacept-based immuno-suppression regime in kidney transplant recipients improves renal function, acid-base derangement and mineral-bone metabolism. | 2017 | J. Nephrol. | pmid:28540602 |
| Woillard JB et al. | Population Pharmacokinetics and Bayesian Estimators for Refined Dose Adjustment of a New Tacrolimus Formulation in Kidney and Liver Transplant Patients. | 2017 | Clin Pharmacokinet | pmid:28389935 |
| Kanate AS et al. | Recipient Immune Modulation with Atorvastatin for Acute Graft-versus-Host Disease Prophylaxis after Allogeneic Transplantation. | 2017 | Biol. Blood Marrow Transplant. | pmid:28412518 |
| Sauer R et al. | Good outcome of brain stem progressive multifocal leukoencephalopathy in an immunosuppressed renal transplant patient: Importance of early detection and rapid immune reconstitution. | 2017 | J. Neurol. Sci. | pmid:28320193 |
| Lepelley M et al. | [Pharmacokinetic drug interaction between miconazole mucoadhesive tablet and tacrolimus: About 3Â case-reports in transplant patients]. | 2017 | Therapie | pmid:28214069 |
| Sikma MA et al. | High tacrolimus blood concentrations early after lung transplantation and the risk of kidney injury. | 2017 | Eur. J. Clin. Pharmacol. | pmid:28132082 |
| Keller F et al. | Correlation between pharmacokinetics of tacrolimus and pharmacodynamics on NFAT-regulated gene expression in stable kidney transplant recipients
. | 2017 | Clin. Nephrol. | pmid:28025957 |
| Ren L et al. | Donors FMO3 polymorphisms affect tacrolimus elimination in Chinese liver transplant patients. | 2017 | Pharmacogenomics | pmid:28084894 |
| Zhu LB et al. | Efficacy and Safety of Tacrolimus Versus Cyclophosphamide for Primary Membranous Nephropathy: A Meta-Analysis. | 2017 | Drugs | pmid:28084563 |
| Qi JC et al. | Tacrolimus protects vascular endothelial cells from injuries caused by Ox-LDL by regulating endoplasmic reticulum stress. | 2017 | Eur Rev Med Pharmacol Sci | pmid:28975964 |
| Dabrowska-Zamojcin E et al. | KCNJ11 and KCNQ1 Gene Polymorphisms Are Not Associated with Post-Transplant Diabetes Mellitus in Kidney Allograft Recipients Treated with Tacrolimus. | 2017 | Folia Biol. (Praha) | pmid:28805561 |
| Wood LA et al. | New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision. | 2017 | J. Cell Biol. | pmid:28954824 |