Morris RE |
In vivo immunopharmacology of the macrolides FK 506 and rapamycin: toward the era of rational immunosuppressive drug discovery, development, and use. |
1991 |
Transplant. Proc. |
pmid:1721257
|
Kobayashi M et al. |
FK 506 assay past and present--characteristics of FK 506 ELISA. |
1991 |
Transplant. Proc. |
pmid:1721258
|
Warty VS et al. |
Practical aspects of FK 506 analysis (Pittsburgh experience). |
1991 |
Transplant. Proc. |
pmid:1721259
|
Jusko WJ and D'Ambrosio R |
Monitoring FK 506 concentrations in plasma and whole blood. |
1991 |
Transplant. Proc. |
pmid:1721260
|
Venkataramanan R et al. |
Pharmacokinetics of FK 506 in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721261
|
Christians U et al. |
High performance liquid chromatography/mass spectrometry of FK 506 and its metabolites in blood, bile, and urine of liver grafted patients. |
1991 |
Transplant. Proc. |
pmid:1721262
|
Beysens AJ et al. |
FK 506: monitoring in plasma or in whole blood? |
1991 |
Transplant. Proc. |
pmid:1721263
|
Grenier FC et al. |
A whole blood FK 506 assay for the IMx analyzer. |
1991 |
Transplant. Proc. |
pmid:1721264
|
Blanc P et al. |
Antiproliferative effect of FK 506 and cyclosporine on adult human hepatocytes in culture. |
1991 |
Transplant. Proc. |
pmid:1721288
|
Loréal O et al. |
FK 506 is less cytotoxic than cyclosporine to human and rat hepatocytes in vitro. |
1991 |
Transplant. Proc. |
pmid:1721289
|
McCauley J et al. |
Cyclosporine and FK 506 induced inhibition of renal epithelial cell proliferation. |
1991 |
Transplant. Proc. |
pmid:1721290
|
McLachlan G et al. |
Growth inhibition of the MOLT-4 human T-leukemia cell line. A comparison of cyclosporine and FK 506. |
1991 |
Transplant. Proc. |
pmid:1721291
|
Akselband Y et al. |
Rapamycin inhibits spontaneous and fibroblast growth factor beta-stimulated proliferation of endothelial cells and fibroblasts. |
1991 |
Transplant. Proc. |
pmid:1721292
|
Schreiber SL et al. |
Immunophilin-ligand complexes as probes of intracellular signaling pathways. |
1991 |
Transplant. Proc. |
pmid:1721293
|
Ullman KS et al. |
Site of action of cyclosporine and FK 506 in the pathways of communication between the T-lymphocyte antigen receptor and the early activation genes. |
1991 |
Transplant. Proc. |
pmid:1721294
|
Sigal NH et al. |
Is FKBP involved in the immunosuppressive and/or toxic mechanism of action of FK 506? |
1991 |
Transplant. Proc. |
pmid:1721295
|
Bierer BE et al. |
FK 506 and rapamycin: molecular probes of T-lymphocyte activation. |
1991 |
Transplant. Proc. |
pmid:1721296
|
Chen-Woan M et al. |
Diminished lymphocyte growth from endomyocardial biopsies from cardiac transplant patients on FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721320
|
Fukuzawa M et al. |
Effect of FK 506 on CD4+ and CD8+ T-cell function in vivo. |
1991 |
Transplant. Proc. |
pmid:1721321
|
Takaori K et al. |
Effects of FK 506 on in vivo immunity in comparison to cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721322
|
Jordan ML et al. |
Inhibition of T-cell function by FK 506 and cyclosporine is not accompanied by alterations in intracellular calcium. |
1991 |
Transplant. Proc. |
pmid:1721323
|
Motta I et al. |
FK 506 favors the generation of memory T cells in vitro. |
1991 |
Transplant. Proc. |
pmid:1721324
|
Nakata S et al. |
Immunosuppressive effect of FK 506 on cytotoxic T lymphocytes and delayed-type hypersensitivity in rats. |
1991 |
Transplant. Proc. |
pmid:1721325
|
Cooper MH et al. |
Evaluation of the influence of FK 506, rapamycin, and cyclosporine on processing and presentation of particulate antigen by macrophages: assessment of a drug "carry-over" effect. |
1991 |
Transplant. Proc. |
pmid:1721326
|
Didlake R and Grogan J |
Effect of FK 506 on rat leukocyte chemotaxis. |
1991 |
Transplant. Proc. |
pmid:1721327
|
Schreiber SL |
Chemistry and biology of the immunophilins and their immunosuppressive ligands. |
1991 |
Science |
pmid:1702904
|
Wasik M et al. |
Effect of FK506 versus cyclosporine on human natural and antibody-dependent cytotoxicity reactions in vitro. |
1991 |
Transplantation |
pmid:1702910
|
Green M et al. |
Infectious complications of pediatric liver transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721352
|
Carroll PB et al. |
Effect of the immunosuppressant FK506 on glucose-induced insulin secretion from adult rat islets of Langerhans. |
1991 |
Transplantation |
pmid:1702911
|
Torre-Cisneros J et al. |
The spectrum of aspergillosis in liver transplant patients: comparison of FK 506 and cyclosporine immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721353
|
Paul AA et al. |
CMV retinitis and the use of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721354
|
Reyes J et al. |
Posttransplant lymphoproliferative disorders occurring under primary FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721355
|
Whiteside TL et al. |
Serial monitoring of immunologic function and phenotype of lymphocytes in the blood of transplanted patients randomized to cyclosporine or FK 506. |
1991 |
Transplant. Proc. |
pmid:1721356
|
Van Thiel DH et al. |
Interferon therapy of hepatitis following liver transplantation under FK 506 or cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1721357
|
Armitage JM et al. |
The clinical trial of FK 506 as primary and rescue immunosuppression in adult cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721358
|
Armitage JM et al. |
The clinical trial of FK 506 as primary and rescue immunosuppression in pediatric cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721359
|
Dew MA et al. |
Quality-of-life advantages of FK 506 vs conventional immunosuppressive drug therapy in cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721360
|
Demetris AJ et al. |
Histopathology of human renal allograft rejection under FK 506: a comparison with cyclosporine. |
1991 |
Transplant. Proc. |
pmid:1703360
|
Thomson AW et al. |
The influence of FK 506 on the thymus: implications of drug-induced injury to thymic epithelial cells. |
1991 |
Transplant. Proc. |
pmid:1703361
|
Mieles L et al. |
Glycemia and insulin need following FK 506 rescue therapy in liver transplant recipients. |
1991 |
Transplant. Proc. |
pmid:1703362
|
Warty V et al. |
Distribution of FK 506 in plasma lipoproteins in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1703363
|
Kusne S et al. |
Early infections in kidney transplant recipients under FK 506. |
1991 |
Transplant. Proc. |
pmid:1703364
|
McCauley J et al. |
Changes in renal function after liver transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721385
|
Tauxe WN et al. |
A comparison of the renal effects (ERPF, GFR, and FF) of FK 506 and cyclosporine in patients with liver transplantation. |
1991 |
Transplant. Proc. |
pmid:1721386
|
McCauley J et al. |
Renal function after conversion from cyclosporine to FK 506 in liver transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721387
|
Hossein-Nia M et al. |
Urinary proteins as a marker of drug-induced renal damage following treatment with cyclosporine or FK 506. |
1991 |
Transplant. Proc. |
pmid:1721388
|
Winkler M et al. |
Association of elevated FK 506 plasma levels with nephrotoxicity in liver-grafted patients. |
1991 |
Transplant. Proc. |
pmid:1721389
|
Schmidt RJ et al. |
Hemolytic-uremic syndrome in a renal transplant recipient on FK 506 immunosuppression. |
1991 |
Transplant. Proc. |
pmid:1721390
|
Tze WJ et al. |
Effect of FK 506 on glucose metabolism and insulin secretion in normal rats. |
1991 |
Transplant. Proc. |
pmid:1721391
|
Doi R et al. |
Mechanisms by which FK 506 affects exocrine pancreas in rats. |
1991 |
Transplant. Proc. |
pmid:1721392
|
Rilo HL et al. |
Effect of FK 506 on function of human islets of Langerhans. |
1991 |
Transplant. Proc. |
pmid:1721393
|
Fukuzaki T et al. |
Induction of tolerance to islet allografts with preoperative donor spleen cell injection and a short course of FK 506 treatment. |
1991 |
Transplant. Proc. |
pmid:1721415
|
Tzakis AG et al. |
FK 506 rescue in chronic graft-versus-host-disease after bone marrow transplantation. |
1991 |
Transplant. Proc. |
pmid:1721416
|
Masaoka T et al. |
Phase II study of FK 506 for allogeneic bone marrow transplantation. |
1991 |
Transplant. Proc. |
pmid:1721417
|
Steinmann B et al. |
Mechanism of action of FK 506 and cyclosporin. |
1991 |
Lancet |
pmid:1704088
|
Markus PM et al. |
The effect of cyclosporine, rapamycin and FK 506 the survival following allogeneic bone marrow transplantation. |
1991 |
Transplant. Proc. |
pmid:1721418
|
Sewing KF and Christians U |
FK 506. |
1991 |
Lancet |
pmid:1704090
|
Cooper MH et al. |
The induction of pseudo-graft-versus-host disease following syngeneic bone marrow transplantation using FK 506. |
1991 |
Transplant. Proc. |
pmid:1721419
|
Boggs S et al. |
FK 506 has no short-term effects on endogenous or exogenous myeloid reconstitution in irradiated mice. |
1991 |
Transplant. Proc. |
pmid:1721420
|
Cooper MH et al. |
Prolonged prevention of acute graft-versus-host disease after allogeneic bone marrow transplantation by donor pretreatment using FK 506. |
1991 |
Transplant. Proc. |
pmid:1721421
|
Yoshimi F et al. |
Canine total orthotopic small bowel transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721422
|
Santiago SF et al. |
Effect of donor pretreatment with FK 506 upon small intestine allotransplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721423
|
Ringe D |
Immunosuppression. Binding by design. |
1991 |
Nature |
pmid:1710317
|
Tropschug M and Hofmann R |
FK506 and protein kinase C. |
1991 |
Nature |
pmid:1710319
|
Albers MW et al. |
Relationship of FKBP to PKCI-2. |
1991 |
Nature |
pmid:1710782
|
Stevens C et al. |
The effects of immunosuppressive agents on in vitro production of human immunoglobulins. |
1991 |
Transplantation |
pmid:1710843
|
Metcalfe S and Milner J |
Evidence that FK506 and rapamycin block T cell activation at different sites relative to early reversible phosphorylation involving the protein phosphatases PP1 and PP2A. |
1991 |
Transplantation |
pmid:1710844
|
Fabrega AJ et al. |
FK 506 enhances the beneficial effects of donor-specific blood transfusion on allograft survival in rats. |
1991 |
Transplant. Proc. |
pmid:1721447
|
Chang JY et al. |
FK506 and rapamycin: novel pharmacological probes of the immune response. |
1991 |
Trends Pharmacol. Sci. |
pmid:1710854
|
Davies CB et al. |
Effects of donor-specific transfusion, cyclosporine A and FK 506 on rat cardiac allograft survival. |
1991 |
Transplant. Proc. |
pmid:1721448
|
Neuberger J |
FK 506--a promise of good things to come? |
1991 |
Hepatology |
pmid:1711005
|
Abu-Elmagd K et al. |
FK 506: a new therapeutic agent for severe recalcitrant psoriasis. |
1991 |
Transplant. Proc. |
pmid:1721449
|
Halloran PF and Madrenas J |
The mechanism of action of cyclosporine: a perspective for the 90's. |
1991 |
Clin. Biochem. |
pmid:1711939
|
Nikolaidis NL et al. |
Metabolic effects of FK 506 in patients with severe psoriasis: short-term follow-up of seven cases. |
1991 |
Transplant. Proc. |
pmid:1721450
|
Palaszynski EW et al. |
Purification and characterization of cyclosporine and FK-506 binding proteins from a human T-helper cell line. |
1991 |
Clin. Biochem. |
pmid:1711940
|
Abu-Elmagd K et al. |
Efficacy of FK 506 in the treatment of recalcitrant pyoderma gangrenosum. |
1991 |
Transplant. Proc. |
pmid:1721451
|
Thomson AW et al. |
Influence of FK 506 on T lymphocytes, Langerhans' cells and the expression of cytokine receptors and adhesion molecules in psoriatic skin lesions: a preliminary study. |
1991 |
Transplant. Proc. |
pmid:1721452
|
Sainsbury TS et al. |
Differential effects of FK 506 and cyclosporine on hair regrowth in the DEBR model of alopecia areata. |
1991 |
Transplant. Proc. |
pmid:1721453
|
Fujino Y et al. |
FK 506 treatment of experimental autoimmune uveoretinitis in primates. |
1991 |
Transplant. Proc. |
pmid:1721454
|
Liversidge J et al. |
FK 506 modulates accessory cell adhesion molecule expression and inhibits CD4 lymphocyte adhesion to retinal pigment epithelial cells in vitro: implications for therapy of uveoretinitis. |
1991 |
Transplant. Proc. |
pmid:1721455
|
Starzl TE et al. |
Notes on FK 506. |
1991 |
Transplant. Proc. |
pmid:1714647
|
Haba T et al. |
Pathological and immunohistochemical examination in the rat treated with FK 506. |
1991 |
Transplant. Proc. |
pmid:1714649
|
Forrest MJ et al. |
FK-506 and cyclosporin A: selective inhibition of calcium ionophore-induced polymorphonuclear leukocyte degranulation. |
1991 |
Biochem. Pharmacol. |
pmid:1716098
|
Lautenschlager I et al. |
Efficiency of FK 506 and CyA to prevent acute cellular rejection of pig liver allografts. |
1991 |
Transplant. Proc. |
pmid:1714650
|
DiLella AG and Craig RJ |
Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains. |
1991 |
Biochemistry |
pmid:1716149
|
Epand RF and Epand RM |
The new potent immunosuppressant FK-506 reverses multidrug resistance in Chinese hamster ovary cells. |
1991 |
Anticancer Drug Des. |
pmid:1714737
|
McKeon F |
When worlds collide: immunosuppressants meet protein phosphatases. |
1991 |
Cell |
pmid:1716181
|
Christians U et al. |
Isolation of an immunosuppressive metabolite of FK506 generated by human microsome preparations. |
1991 |
Clin. Biochem. |
pmid:1714802
|
Petros AM et al. |
NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding. |
1991 |
J. Med. Chem. |
pmid:1716684
|
Turka LA and Thompson CB |
Structure-function relationship of immunosuppressive drugs: a cautionary tale. |
1991 |
Hepatology |
pmid:1714876
|
|
FK 506--an investigational immunosuppressant. |
1991 |
Med Lett Drugs Ther |
pmid:1716722
|
Ochiai T et al. |
[Immunosuppressive agents--advances of the developmental studies and the mode of action]. |
1991 |
Nippon Rinsho |
pmid:1715926
|
Brizuela L et al. |
Antifungal properties of the immunosuppressant FK-506: identification of an FK-506-responsive yeast gene distinct from FKB1. |
1991 |
Mol. Cell. Biol. |
pmid:1715022
|
Heitman J et al. |
Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. |
1991 |
Science |
pmid:1715094
|
Jiang H et al. |
Effect of FK-506 on heart allograft survival in the highly sensitized recipient rats as compared with ciclosporin and 15-deoxyspergualin. |
1991 |
Eur Surg Res |
pmid:1723683
|
Fung JJ et al. |
Conversion of liver allograft recipients from cyclosporine to FK 506-based immunosuppression: benefits and pitfalls. |
1991 |
Transplant. Proc. |
pmid:1703682
|
Wu J et al. |
Comparative immunoregulatory effects of rapamycin, FK 506 and cyclosporine on mitogen-induced cytokine production and lymphoproliferation. |
1991 |
Transplant. Proc. |
pmid:1703683
|
Yoshimura R et al. |
A comparative study between cyclosporine and FK 506 effects on renal microsomal P-450. |
1991 |
Transplant. Proc. |
pmid:1703686
|
Miyagawa S et al. |
Mechanism of unresponsiveness in rats induced by a short course of FK 506 or CyA. |
1991 |
Transplant. Proc. |
pmid:1703687
|
Carroll PB et al. |
Effect of the immunosuppressant FK 506 on insulin release from adult rat islets of Langerhans. |
1991 |
Transplant. Proc. |
pmid:1703688
|