tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Lichenoid Eruptions D017512 1 associated lipids
Feline Infectious Peritonitis D016766 1 associated lipids
Meningitis, Cryptococcal D016919 1 associated lipids
Oculomotor Nerve Diseases D015840 1 associated lipids
Cutis Laxa D003483 1 associated lipids
Invasive Pulmonary Aspergillosis D055744 1 associated lipids
Intestinal Volvulus D045822 1 associated lipids
Hand Injuries D006230 1 associated lipids
Beckwith-Wiedemann Syndrome D001506 1 associated lipids
Eye Diseases, Hereditary D015785 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
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Authors Title Published Journal PubMed Link
Segura S et al. Eczema herpeticum during treatment of atopic dermatitis with 1% pimecrolimus cream. 2005 Acta Derm. Venereol. pmid:16396803
Jungersted JM et al. Effects of topical corticosteroid and tacrolimus on ceramides and irritancy to sodium lauryl sulphate in healthy skin. 2011 Acta Derm. Venereol. pmid:21365172
Quist SR et al. Effects of Topical Tacrolimus and Polyunsaturated Fatty Acids on In Vivo Release of Eicosanoids in Atopic Dermatitis During Dermal Microdialysis. 2016 Acta Derm. Venereol. pmid:26911315
Zattra E et al. Labial melanotic macule after application of topical tacrolimus: two case reports. 2010 Acta Derm. Venereol. pmid:20814635
Hartmann A et al. Treatment of generalised vitiligo with tacrolimus 0.1% ointment vs. UVB intense pulsed light phototherapy: a pilot study. 2014 Acta Derm. Venereol. pmid:24473666
Hao D et al. Lymphocytic infiltration of the eyelid: two cases responding to tacrolimus and topical glucocorticoid. 2013 Acta Derm. Venereol. pmid:23423497
Pagliarello C and Paradisi A Topical tacrolimus is useful for avoiding suction-blister epidermal grafting depigmentation in non-segmental vitiligo: a case report. 2012 Acta Derm. Venereol. pmid:22101735
Mandelin J et al. Leg ulcers treated with topical tacrolimus in patients with rheumatoid arthritis. 2010 Acta Derm. Venereol. pmid:21057750
Nakamizo S et al. Treatment of neuropathic itch possibly due to trigeminal trophic syndrome with 0.1% topical tacrolimus and gabapentin. 2010 Acta Derm. Venereol. pmid:21057761
Mandelin J et al. One-year treatment with 0.1% tacrolimus ointment versus a corticosteroid regimen in adults with moderate to severe atopic dermatitis: A randomized, double-blind, comparative trial. 2010 Acta Derm. Venereol. pmid:20169301
Ujiie H et al. Successful treatment of nail lichen planus with topical tacrolimus. 2010 Acta Derm. Venereol. pmid:20169322
Inoue T et al. Prolonged topical application of tacrolimus inhibits immediate hypersensitivity reactions by reducing degranulation of mast cells. 2006 Acta Derm. Venereol. pmid:16585982
Ortonne JP et al. 0.3% Tacrolimus gel and 0.5% Tacrolimus cream show efficacy in mild to moderate plaque psoriasis: Results of a randomized, open-label, observer-blinded study. 2006 Acta Derm. Venereol. pmid:16585986
Tzung TY et al. Pimecrolimus and narrowband UVB as monotherapy or combination therapy in children and adolescents with atopic dermatitis. 2006 Acta Derm. Venereol. pmid:16585987
Pitarch G et al. Systemic absorption of topical tacrolimus in Pyoderma gangrenosum. 2006 Acta Derm. Venereol. pmid:16585995
Cunha PR Pimecrolimus cream 1% is effective in seborrhoeic dermatitis refractory to treatment with topical corticosteroids. 2006 Acta Derm. Venereol. pmid:16585998
Cunha PR and Rossi AB Pimecrolimus cream 1% is effective in a case of granulomatous rosacea. 2006 Acta Derm. Venereol. pmid:16585999
De Rie MA et al. Soluble interleukin-2 receptor (sIL-2R) is a marker of disease activity in psoriasis: a comparison of sIL-2R, sCD27, sCD4, sCD8 and sICAM-1. 1996 Acta Derm. Venereol. pmid:8891007
Yamamoto T and Nishioka K Deep dermatophytosis during topical tacrolimus therapy for psoriasis. 2003 Acta Derm. Venereol. pmid:12926803
Sand C Topical tacrolimus ointment may induce skin tags in treated patients. 2003 Acta Derm. Venereol. pmid:12926817